2,855 research outputs found

    Zika Virus: Infectious Process and Public Health Response

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    The Zika virus has become a growing concern as a global pandemic. Since being identified in Uganda in 1947, the virus has spread around the world, recently emerging in South America with a great impact on Brazil. As of 2016, Zika has made its appearance in the United States and is now actively being transmitted in Florida. The virus is a mosquito-vectored flavivirus primarily transmitted by the Aedes mosquito which infects a human through biting. Transmission through sexual intercourse is also possible as well as transmission from a pregnant woman to her fetus. This latter form of transmission presents the primary problem with the Zika virus; transmission to the fetus can cause microcephaly as well as other brain and developmental problems. Proper precautions should be taken based on these identified modes of transmission. Symptoms of Zika are similar to flu-like symptoms, such as low-grade fever, muscle pain and headache. About 20 percent of patients that come in contact with the Zika virus will originally present as asymptomatic and will not display symptoms until almost two weeks after initial contact with the virus. Zika virus can remain in the blood for about a week, but can remain in the semen for months. There are a number of methods used to detect the Zika virus—urine, blood or semen samples may be used to assess if a patient is infected

    Complete genome sequence of Liberibacter crescens BT-1

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    Liberibacter crescens BT-1, a Gram-negative, rod-shaped bacterial isolate, was previously recovered from mountain papaya to gain insight on Huanglongbing (HLB) and Zebra Chip (ZC) diseases. The genome of BT-1 was sequenced at the Interdisciplinary Center for Biotechnology Research (ICBR) at the University of Florida. A finished assembly and annotation yielded one chromosome with a length of 1,504,659 bp and a G+C content of 35.4%. Comparison to other species in the Liberibacter genus, L. crescens has many more genes in thiamine and essential amino acid biosynthesis. This likely explains why L. crescens BT-1 is culturable while the known Liberibacter strains have not yet been cultured. Similar to Candidatus L. asiaticus psy62, the L. crescens BT-1 genome contains two prophage regions

    How to Carry Out Bathymetric and Elevation Surveys on a Tight Budget: Basic Surveying Techniques for Sustainabilty Scientists

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    Sustainability scientists often face a difficult task to conduct research or carry out preliminary investigations around coastal areas in developing countries, due to the limitation in the availability of topographical and bathymetry data. These limitations can be particularly important for the case of ports, on which the livelihoods of many fishing communities depend on. Often, cost is cited as a reason regarding the absence of any such data. However, in the present technical note the authors highlight how existing “low-level” surveying methods can be inexpensive and allow sustainability scientists to conduct a reasonably accurate survey for less than 1,000 USD, provided that researchers possess a reasonable knowledge of mathematics and geometry (high-school equivalent)

    State and Agriculture in Africa: A Case of Means and Ends

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    SUMMARY This article examines the argument that the problems of implementing the development programmes of African governments arise from the political necessity to maintain power. In response to this, it is argued that the success and failure of policies, the distortive effects of sectional interests and the necessity to use particular methods to maintain power are determined by a wider context, that of the state as a whole, and its social role in creating and sustaining the institutions — political and economic — which regulate relations between the citizens of African states. SOMMAIRE Cet article examine l'argument selon lequel les problĂšmes de mĂŹse en oeuvre et de dĂ©veloppement des programmes des gouvernements africains, proviennent de la nĂ©cessitĂ© politique de maintenir le pouvoir. En rĂ©ponse Ă  cela, il est argumentĂ© que le succĂšs et l'Ă©chec des politiques, les effets de distorsĂ­on des intĂ©rĂȘts sectoriels et la nĂ©cessitĂ© d'utiliser des mĂ©thodes particuliĂšres pour maintenir le pouvoir, sont dĂ©terminĂ©s par un contexte plus large celui de l'Ă©tat, et son rĂŽle social de crĂ©er et de soutenir les institutions — politiques et Ă©conomiques — qui rĂ©gissent les relations entre les citoyens des Ă©tats africains. RESUMEN Este articulo examina el argumento de que los problema de los gobiernos africanos para implementar programas de desarrollo, surge de la necesidad polĂ­tica de mantener el poder. En respuesta a esto, se arguye que los exitos y fracasos de la polĂ­ticas, los efectos distorsionadores de intereses contrapuestos y la necesidad de usar mĂ©todos especiales para mantener el poder, estĂĄn determinados por un contexto mas amplio que consiste en el estado como un todo y en su rol social en la creaciĂłn y mantenciĂłn de las instituciones — polĂ­ticas y econĂłmicas — que regulan las relaciones entre los ciudadanos de los estados africanos

    Early stressful experiences are associated with reduced neural responses to naturalistic emotional and social content in children

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    How do children’s experiences relate to their naturalistic emotional and social processing? Because children can struggle with tasks in the scanner, we collected fMRI data while 4-to-11-year-olds watched a short film with positive and negative emotional events, and rich parent-child interactions (n = 70). We captured broad, normative stressful experiences by examining socioeconomic status (SES) and stressful life events, as well as children’s more proximal experiences with their parents. For a sub-sample (n = 30), parenting behaviors were measured during a parent-child interaction, consisting of a picture book, a challenging puzzle, and free play with novel toys. We characterized positive parenting behaviors (e.g., warmth, praise) and negative parenting behaviors (e.g., harsh tone, physical control). We found that higher SES was related to greater activity in medial orbitofrontal cortex during parent-child interaction movie events. Negative parenting behaviors were associated with less activation of the ventral tegmental area and cerebellum during positive emotional events. In a region-of-interest analysis, we found that stressful life events and negative parenting behaviors were associated with less activation of the amygdala during positive emotional events. These exploratory results demonstrate the promise of using movie fMRI to study how early experiences may shape emotional, social, and motivational processes

    From Human Days to Machine Seconds: Automatically Answering and Generating Machine Learning Final Exams

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    A final exam in machine learning at a top institution such as MIT, Harvard, or Cornell typically takes faculty days to write, and students hours to solve. We demonstrate that large language models pass machine learning finals at a human level, on finals available online after the models were trained, and automatically generate new human-quality final exam questions in seconds. Previous work has developed program synthesis and few-shot learning methods to solve university-level problem set questions in mathematics and STEM courses. In this work, we develop and compare methods that solve final exams, which differ from problem sets in several ways: the questions are longer, have multiple parts, are more complicated, and span a broader set of topics. We curate a dataset and benchmark of questions from machine learning final exams available online and code for answering these questions and generating new questions. We show how to generate new questions from other questions and course notes. For reproducibility and future research on this final exam benchmark, we use automatic checkers for multiple-choice, numeric, and questions with expression answers. We perform ablation studies comparing zero-shot learning with few-shot learning and chain-of-thought prompting using GPT-3, OPT, Codex, and ChatGPT across machine learning topics and find that few-shot learning methods perform best. We highlight the transformative potential of language models to streamline the writing and solution of large-scale assessments, significantly reducing the workload from human days to mere machine seconds. Our results suggest that rather than banning large language models such as ChatGPT in class, instructors should teach students to harness them by asking students meta-questions about correctness, completeness, and originality of the responses generated, encouraging critical thinking in academic studies.Comment: 9 page
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