1,885 research outputs found

    Biogeophysical controls on soil-atmosphere thermal differences: implications on warming Arctic ecosystems

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    Soil temperature (ST) has a key role in Arctic ecosystem functioning and global environmental change. However, soil thermal conditions do not necessarily follow synoptic temperature variations. This is because local biogeophysical processes can lead to a pronounced soil-atmosphere thermal offset (∆T) while altering the coupling (βT) between ST and ambient air temperature (AAT). Here, we aim to uncover the spatiotemporal variation in these parameters and identify their main environmental drivers. By deploying a unique network of 322 temperature loggers and surveying biogeophysical processes across an Arctic landscape, we found that the spatial variation in ∆T during the AAT≤0 period (mean ∆T=-0.6°C, standard deviation ± 1.0°C) was directly and indirectly constrained by local topography controlling snow depth. By contrast, during the AAT>0 period, ∆T was controlled by soil characteristics, vegetation and solar radiation (∆T=6.0°C ± 1.2°C). Importantly, ∆T was not constant throughout the seasons reflecting the influence of βT on the rate of local soil warming being stronger after (mean βT = 0.8 ± 0.1) than before (βT = 0.2 ± 0.2) snowmelt. Our results highlight the need for continuous microclimatic and local environmental monitoring, and suggest a potential for large buffering and non-uniform warming of snow-dominated Arctic ecosystems under projected temperature increase

    The long-term effect of complex regional pain syndrome type 1 on disability and quality of life after foot injury

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    PURPOSE: To study the long-term evolution of patients with lower-limb Complex Regional Pain Syndrome (CRPS), focusing on functional and proprioceptive aspects and quality of life. METHODS: In 20 patients suffering from chronic distal lower-limb CRPS diagnosed using Budapest criteria, we assessed joint position sense and strength of the knee muscles at the CRPS and unaffected leg, functional exercise capacity, pain, CRPS severity score, quality of life and kinesiophobia. Similar assessments were performed in 20 age-matched controls. RESULTS: The joint position performance (at 45°) was significantly lower for the CRPS leg as compared to controls. The knee extensor strength of the CRPS leg was significantly reduced as compared to the unaffected leg (−27%) and controls (−42%). CRPS patients showed significantly reduced performance at the 6 min-walk test as compared to their age group predicted value and controls. Patients suffering from CRPS for 3.8 years in average still exhibit high pain, severity and kinesiophobia scores. CONCLUSIONS: Long-term deficits in strength and proprioceptive impairments are observed at the knee joint of the CRPS leg. This persistent functional disability has significant repercussions on the quality of life. We highlight the importance of including strength and proprioceptive exercises in the therapeutic approaches for CPRS patients

    Mortality in non-exacerbating COPD: a longitudinal analysis of UK primary care data

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    Introduction: Non-exacerbating patients with chronic obstructive pulmonary disease (COPD) are a less studied phenotype. We investigated clinical characteristics, mortality rates and causes of death among non-exacerbating compared with exacerbating patients with COPD. Methods: We used data from the Clinical Practice Research Datalink, Hospital Episode Statistics and Office for National Statistics between 1 January 2004 and 31 December 2018. Ever smokers with a COPD diagnosis with minimum 3 years of baseline information were included. We compared overall using Cox regression and cause-specific mortality rates using competing risk analysis, adjusted for age, sex, deprivation, smoking status, body mass index, GOLD stage and comorbidities. Causes of death were identified using International Classification of Diseases-10 codes. Results: Among 67 516 patients, 17.3% did not exacerbate during the 3-year baseline period. Mean follow-up was 4 years. Non-exacerbators were more likely to be male (63.3% vs 52.4%, p<0.001) and less often had a history of asthma (33.9% vs 43.6%, p<0.001) or FEV1<50% predicted (23.7 vs 31.8%) compared with exacerbators. Adjusted HR for overall mortality in non-exacerbators compared with exacerbators was 0.62 (95% CI 0.56 to 0.70) in the first year of follow-up and 0.87 (95% CI 0.83 to 0.91) thereafter. Non-exacerbating patients with COPD died less of respiratory causes than exacerbators (29.2% vs 40.3%) and more of malignancies (29.4% vs 23.4%) and cardiovascular diseases (26.2% vs 22.9%). HRs for malignant and circulatory causes of death were increased after the first year of follow-up. Discussion: In this primary care cohort, non-exacerbators showed distinct clinical characteristics and lower mortality rates. Non-exacerbators were equally likely to die of respiratory, malignant or cardiovascular diseases

    The Yo-Yo intermittent recovery test level 1 is reliable in young high-level soccer players

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    The aim of the study was to investigate test reliability of the Yo-Yo intermittent recovery test level 1 (YYIR1) in 36 high-level youth soccer players, aged between 13 and 18 years. Players were divided into three age groups (U15, U17 and U19) and completed three YYIR1 in three consecutive weeks. Pairwise comparisons were used to investigate test reliability (for distances and heart rate responses) using technical error (TE), coefficient of variation (CV), intra-class correlation (ICC) and limits of agreement (LOA) with Bland-Altman plots. The mean YYIR1 distances for the U15, U17 and U19 groups were 2024 ± 470 m, 2404 ± 347 m and 2547 ± 337 m, respectively. The results revealed that the TEs varied between 74 and 172 m, CVs between 3.0 and 7.5%, and ICCs between 0.87 and 0.95 across all age groups for the YYIR1 distance. For heart rate responses, the TEs varied between 1 and 6 bpm, CVs between 0.7 and 4.8%, and ICCs between 0.73 and 0.97. The small ratio LOA revealed that any two YYIR1 performances in one week will not differ by more than 9 to 28% due to measurement error. In summary, the YYIR1 performance and the physiological responses have proven to be highly reliable in a sample of Belgian high-level youth soccer players, aged between 13 and 18 years. The demonstrated high level of intermittent endurance capacity in all age groups may be used for comparison of other prospective young soccer players

    Preconditioner-Based Contact Response and Application to Cataract Surgery

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    International audienceIn this paper we introduce a new method to compute, in real-time, the physical behavior of several colliding soft-tissues in a surgical simulation. The numerical approach is based on finite element modeling and allows for a fast update of a large number of tetrahedral elements. The speed-up is obtained by the use of a specific preconditioner that is updated at low frequency. The preconditioning enables an optimized computation of both large deformations and precise contact response. Moreover, homogeneous and inhomogeneous tissues are simulated with the same accuracy. Finally, we illustrate our method in a simulation of one step in a cataract surgery procedure, which require to handle contacts with non homogeneous objects precisely

    Phase II study in young CF adults with the recombinant acid lipase MERISPASE®

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    Relative age, biological maturation and anaerobic characteristics in elite youth soccer players

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    Being relatively older and having an advanced biological maturation status have been associated with increased likelihood of selection in young elite soccer players. The aims of the study were to investigate the presence of a relative age effect (RAE) and the influence of birth quarter on anthropometry, biological maturity and anaerobic parameters in 374 elite Belgian youth soccer players. The sample was divided into 3 age groups, each subdivided into 4 birth quarters (BQ). Players had their APHV estimated and height, weight, SBJ, CMJ, sprint 5 and 30 m were assessed. Overall, more players were born in BQ1 (42.3%) compared with players born in BQ4 (13.7%). Further, MANCOVA revealed no differences in all parameters between the 4 BQ's, controlled for age and APHV. These results suggest that relatively youngest players can offset the RAE if they enter puberty earlier. Furthermore, the results demonstrated possible differences between BQ1 and BQ4, suggesting that caution is necessary when estimating differences between players because of large discrepancies between statistical and practical significance. These findings also show that coaches should develop realistic expectations of the physical abilities of younger players and these expectations should be made in the context of biological characteristics rather than chronological age-based standards. © Georg Thieme Verlag KG Stuttgart. New York

    Sampling strategy matters to accurately estimate response curves' parameters in species distribution models

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    Aim: Assessing how different sampling strategies affect the accuracy and precision of species response curves estimated by parametric species distribution models.Major Taxa Studied: Virtual plant species.Location: Abruzzo (Italy).Time Period: Timeless (simulated data).Methods: We simulated the occurrence of two virtual species with different ecology (generalist vs specialist) and distribution extent. We sampled their occurrence following different sampling strategies: random, stratified, systematic, topographic, uniform within the environmental space (hereafter, uniform) and close to roads. For each sampling design and species, we ran 500 simulations at increasing sampling efforts (total: 42,000 replicates). For each replicate, we fitted a binomial generalised linear model, extracted model coefficients for precipitation and temperature, and compared them with true coefficients from the known species' equation. We evaluated the quality of the estimated response curves by computing bias, variance and root mean squared error (RMSE). Additionally, we (i) assessed the impact of missing covariates on the performance of the sampling approaches and (ii) evaluated the effect of incompletely sampling the environmental space on the uniform approach.Results: For the generalist species, we found the lowest RMSE when uniformly sampling the environmental space, while sampling occurrence data close to roads provided the worst performance. For the specialist species, all sampling designs showed comparable outcomes. Excluding important predictors similarly affected all sampling strategies. Sampling limited portions of the environmental space reduced the performance of the uniform approach, regardless of the portion surveyed.Main Conclusions: Our results suggest that a proper estimate of the species response curve can be obtained when the choice of the sampling strategy is guided by the species' ecology. Overall, uniformly sampling the environmental space seems more efficient for species with wide environmental tolerances. The advantage of seeking the most appropriate sampling strategy vanishes when modelling species with narrow realised niches
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