3,216 research outputs found
Li in a Three-Body Model with Realistic Forces: Separable vs. Non-separable Approach
{\bf Background:} Deuteron induced reactions are widely used to probe nuclear
structure and astrophysical information. Those (d,p) reactions may be viewed as
three-body reactions and described with Faddeev techniques.
{\bf Purpose:} Faddeev equations in momentum space have a long tradition of
utilizing separable interactions in order to arrive at sets of coupled integral
equations in one variable. However, it needs to be demonstrated that their
solution based on separable interactions agrees exactly with solutions based on
non-separable forces.
{\bf Results:} The ground state of Li is calculated via momentum space
Faddeev equations using the CD-Bonn neutron-proton force and a Woods-Saxon type
neutron(proton)-He force. For the latter the Pauli-forbidden -wave bound
state is projected out. This result is compared to a calculation in which the
interactions in the two-body subsystems are represented by separable
interactions derived in the Ernst-Shakin-Thaler framework.
{\bf Conclusions:} We find that calculations based on the separable
representation of the interactions and the original interactions give results
that agree to four significant figures for the binding energy, provided an
off-shell extension of the EST representation is employed in both subsystems.
The momentum distributions computed in both approaches also fully agree with
each other
Why are MD simulated protein folding times wrong?
The question of significant deviations of protein folding times simulated using molecular dynamics from experimental values is investigated. It is shown that in the framework of Markov State Model (MSM) describing the conformational dynamics of peptides and proteins, the folding time is very sensitive to the simulation model parameters, such as forcefield and temperature. Using two peptides as examples, we show that the deviations in the folding times can reach an order of magnitude for modest variations of the molecular model. We, therefore, conclude that the folding rate values obtained in molecular dynamics simulations have to be treated with care
Liver cancer immunoassay with magnetic nanoparticles and MgO-based magnetic tunnel junction sensors
This journal issue is proceedings of the 56th 56th Conference on Magnetism and Magnetic MaterialsSession DV - Sensors 2 (Poster Session): no. DV-07We have demonstrated the detection of alpha-fetoprotein (AFP) labeled with magnetic nanoparticles (MNPs) using MgO-based magnetic tunnel junction (MTJ) sensors. AFP is an important hepatic tumor biomarker and the detection of AFP has significant applications for clinical diagnostics and immunoassay for early-stage liver cancer indications. In this work, MgO-based MTJ sensors and 20-nm iron-oxide magnetic nanoparticles (MNPs) were used for detecting AFP antigens by a sandwich-assay configuration. The MTJ sensors with a sensing area of 4 × 2 μm 2 possess tunneling magnetoresistance (TMR) of 122 and sensitivity of 0.95/Oe at room temperature. The target AFP antigens of three concentrations were successfully detected, and the experimental data indicate that the resistance variations of the MTJ sensor increased with the AFP concentration ratios proportionally. These results demonstrate that MgO-based MTJ sensors together with MNPs are a promising biosensing platform for liver cancer immunoassay. © 2012 American Institute of Physics.published_or_final_versionThe 56th Conference on Magnetism and Magnetic Materials, Scottsdale, AZ., 30 October-3 November 2011. In Journal of Applied Physics, 2012, v. 111 n. 7, article no. 07E50
Quantum computation with two-level trapped cold ions beyond Lamb-Dicke limit
We propose a simple scheme for implementing quantum logic gates with a string
of two-level trapped cold ions outside the Lamb-Dicke limit. Two internal
states of each ion are used as one computational qubit (CQ) and the collective
vibration of ions acts as the information bus, i.e., bus qubit (BQ). Using the
quantum dynamics for the laser-ion interaction as described by a generalized
Jaynes-Cummings model, we show that quantum entanglement between any one CQ and
the BQ can be coherently manipulated by applying classical laser beams. As a
result, universal quantum gates, i.e. the one-qubit rotation and two-qubit
controlled gates, can be implemented exactly. The required experimental
parameters for the implementation, including the Lamb-Dicke (LD) parameter and
the durations of the applied laser pulses, are derived. Neither the LD
approximation for the laser-ion interaction nor the auxiliary atomic level is
needed in the present scheme.Comment: 12 pages, no figures, to appear in Phys. Rev.
Sudden drop of fractal dimension of electromagnetic emissions recorded prior to significant earthquake
The variation of fractal dimension and entropy during a damage evolution
process, especially approaching critical failure, has been recently
investigated. A sudden drop of fractal dimension has been proposed as a
quantitative indicator of damage localization or a likely precursor of an
impending catastrophic failure. In this contribution, electromagnetic emissions
recorded prior to significant earthquake are analysed to investigate whether
they also present such sudden fractal dimension and entropy drops as the main
catastrophic event is approaching. The pre-earthquake electromagnetic time
series analysis results reveal a good agreement to the theoretically expected
ones indicating that the critical fracture is approaching
Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice
Fractures are a common comorbidity in children with the neural tube defect (NTD) spina bifida. Mutations in the Wnt/planar cell polarity (PCP) pathway contribute to NTDs in humans and mice, but whether this pathway independently determines bone mass is poorly understood. Here, we first confirmed that core Wnt/PCP components are expressed in osteoblasts and osteoclasts in vitro. In vivo, we performed detailed µCT comparisons of bone structure in tibiae from young male mice heterozygous for NTD-associated mutations versus WT littermates. PCP signalling disruption caused by Vangl2 (Vangl2Lp/+) or Celsr1 (Celsr1Crsh/+) mutations significantly reduced trabecular bone mass and distal tibial cortical thickness. NTD-associated mutations in non-PCP transcription factors were also investigated. Pax3 mutation (Pax3Sp2H/+) had minimal effects on bone mass. Zic2 mutation (Zic2Ku/+) significantly altered the position of the tibia/fibula junction and diminished cortical bone in the proximal tibia. Beyond these genes, we bioinformatically documented the known extent of shared genetic networks between NTDs and bone properties. 46 genes involved in neural tube closure are annotated with bone-related ontologies. These findings document shared genetic networks between spina bifida risk and bone structure, including PCP components and Zic2. Genetic variants which predispose to spina bifida may therefore independently diminish bone mass
Nitrogen Level Changes the Interactions between a Native (Scirpus triqueter) and an Exotic Species (Spartina anglica) in Coastal China
The exotic species Spartina anglica, introduced from Europe in 1963, has been experiencing a decline in the past decade in coastal China, but the reasons for the decline are still not clear. It is hypothesized that competition with the native species Scirpus triqueter may have played an important role in the decline due to niche overlap in the field. We measured biomass, leaf number and area, asexual reproduction and relative neighborhood effect (RNE) of the two species in both monoculture and mixture under three nitrogen levels (control, low and high). S. anglica showed significantly lower biomass accumulation, leaf number and asexual reproduction in mixture than in monoculture. The inter- and intra-specific RNE of S. anglica were all positive, and the inter-specific RNE was significantly higher than the intra-specific RNE in the control. For S. triqueter, inter- and intra-specific RNE were negative at the high nitrogen level but positive in the control and at the low nitrogen level. This indicates that S. triqueter exerted an asymmetric competitive advantage over S. anglica in the control and low nitrogen conditions; however, S. anglica facilitated growth of S. triqueter in high nitrogen conditions. Nitrogen level changed the interactions between the two species because S. triqueter better tolerated low nitrogen. Since S. anglica is increasingly confined to upper, more nitrogen-limited marsh areas in coastal China, increased competition from S. triqueter may help explain its decline
Nanomechanical probing of the layer/substrate interface of an exfoliated InSe sheet on sapphire
Van der Waals (vdW) layered crystals and heterostructures have attracted substantial interest for potential applications in a wide range of emerging technologies. An important, but often overlooked, consideration in the development of implementable devices is phonon transport through the structure interfaces. Here we report on the interface properties of exfoliated InSe on a sapphire substrate. We use a picosecond acoustic technique to probe the phonon resonances in the InSe vdW layered crystal. Analysis of the nanomechanics indicates that the InSe is mechanically decoupled from the substrate and thus presents an elastically imperfect interface. A high degree of phonon isolation at the interface points toward applications in thermoelectric devices, or the inclusion of an acoustic transition layer in device design. These findings demonstrate basic properties of layered structures and so illustrate the usefulness of nanomechanical probing in nanolayer/nanolayer or nanolayer/substrate interface tuning in vdW heterostructures
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