5,050 research outputs found

    Importance of Baryon-Baryon Coupling in Hypernuclei

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    The ΛN−ΣN\Lambda N - \Sigma N coupling in Λ\Lambda--hypernuclei and ΛΛ−ΞN\Lambda \Lambda - \Xi N coupling in ΛΛ\Lambda \Lambda--hypernuclei produce novel physics not observed in the conventional, nonstrange sector. Effects of Λ↔Σ\Lambda \leftrightarrow \Sigma conversion in Λ3^3_{\Lambda}H are reviewed. The role of ΛN−ΣN\Lambda N - \Sigma N coupling suppression in the A=4,5A=4,5 Λ\Lambda--hypernuclei due to Pauli blocking is highlighted, and the implications for the structure of    Λ10^{10}_{\;\, \Lambda}B are explored. Suppression of ΛΛ−ΞN\Lambda \Lambda - \Xi N conversion in ΛΛ     6^{\;\;\, 6}_{\Lambda \Lambda}He is hypothesized as the reason that the matrix element is small. Measurement of ΛΛ     4^{\;\;\, 4}_{\Lambda \Lambda}H is proposed to investigate the full ΛΛ−ΞN\Lambda \Lambda - \Xi N interaction. The implication for ΛΛ\Lambda \Lambda analog states is discussed.Comment: 17 pages LATEX, 1 figure uuencoded postscrip

    Radiocarbon evidence for a possible abyssal front near 3.1 km in the glacial equatorial Pacific Ocean

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    Author Posting. © The Author(s), 2014. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Earth and Planetary Science Letters 425 (2015): 93-104, doi:10.1016/j.epsl.2015.05.025.We investigate the radiocarbon ventilation age in deep equatorial Pacific sediment cores using the difference in conventional 14C age between coexisting benthic and planktonic foraminifera, and integrate those results with similar data from around the North Pacific Ocean in a reconstruction for the last glaciation (15 to 25 conventional 14C ka). Most new data from both the Equatorial Pacific and the Emperor Seamounts in the northwestern Pacific come from maxima in abundance of benthic taxa because this strategy reduces the effect of bioturbation. Although there remains considerable scatter in the ventilation age estimates, on average, ventilation ages in the Equatorial Pacific were significantly greater below 3.2 km (~3080 ±1125 yrs, n=15) than in the depth interval 1.9 to 3.0 km (~1610 ± 250 yrs, n=12). When compared to the average modern seawater Δ14C profile for the North Pacific, the Equatorial Pacific glacial data suggest an abyssal front located somewhere between 3.0 and 3.2 km modern water depth. Above that depth, the data may indicate slightly better ventilation than today, and below that depth, glacial Equatorial Pacific data appear to be as old as last glacial maximum (LGM) deep water ages reported for the deep southern Atlantic. This suggests that a glacial reservoir of aged waters extended throughout the circumpolar Southern Ocean and into the Equatorial Pacific. Renewed ventilation of such a large volume of aged (and, by corollary, carbon-rich) water would help to account for the rise in atmospheric pCO2 and the fall in Δ14C as the glaciation drew to a close.This work was funded by NSF grants OCE-1031224 and OCE-0424861 to LDK and 0851391 to SJL

    Edge theories in Projected Entangled Pair State models

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    We study the edge physics of gapped quantum systems in the framework of Projected Entangled Pair State (PEPS) models. We show that the effective low-energy model for any region acts on the entanglement degrees of freedom at the boundary, corresponding to physical excitations located at the edge. This allows us to determine the edge Hamiltonian in the vicinity of PEPS models, and we demonstrate that by choosing the appropriate bulk perturbation, the edge Hamiltonian can exhibit a rich phase diagram and phase transitions. While for models in the trivial phase any Hamiltonian can be realized at the edge, we show that for topological models, the edge Hamiltonian is constrained by the topological order in the bulk which can e.g. protect a ferromagnetic Ising chain at the edge against spontaneous symmetry breaking.Comment: 5 pages, 4 figure

    Novelty Search in Competitive Coevolution

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    One of the main motivations for the use of competitive coevolution systems is their ability to capitalise on arms races between competing species to evolve increasingly sophisticated solutions. Such arms races can, however, be hard to sustain, and it has been shown that the competing species often converge prematurely to certain classes of behaviours. In this paper, we investigate if and how novelty search, an evolutionary technique driven by behavioural novelty, can overcome convergence in coevolution. We propose three methods for applying novelty search to coevolutionary systems with two species: (i) score both populations according to behavioural novelty; (ii) score one population according to novelty, and the other according to fitness; and (iii) score both populations with a combination of novelty and fitness. We evaluate the methods in a predator-prey pursuit task. Our results show that novelty-based approaches can evolve a significantly more diverse set of solutions, when compared to traditional fitness-based coevolution.Comment: To appear in 13th International Conference on Parallel Problem Solving from Nature (PPSN 2014

    Accounting for decarbonisation and reducing capital at risk in the S&P500

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    This document is the Accepted Manuscript version of the following article: Colin Haslam, Nick Tsitsianis, Glen Lehman, Tord Andersson, and John Malamatenios, ‘Accounting for decarbonisation and reducing capital at risk in the S&P500’, Accounting Forum, Vol. 42 91): 119-129, March 2018. Under embargo until 7 August 2019. The final, definitive version is available online at doi: https://doi.org/10.1016/j.accfor.2018.01.004.This article accounts for carbon emissions in the S&P 500 and explores the extent to which capital is at risk from decarbonising value chains. At a global level it is proving difficult to decouple carbon emissions from GDP growth. Top-down legal and regulatory arrangements envisaged by the Kyoto Protocol are practically redundant given inconsistent political commitment to mitigating global climate change and promoting sustainability. The United Nations Environment Programme (UNEP) and European Commission (EC) are promoting the role of financial markets and financial institutions as drivers of behavioural change mobilising capital allocations to decarbonise corporate activity.Peer reviewe

    Take Care- Use Antibiotics Responsibly Swine Practitioner Project

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    The Take Care - Use Antibrotics Responsibly® program is an antimicrobial resistance and use educat1on and awareness program for pork producers. The program is based on principles and guidelines intended to minimize the development of antimicrobial resistance whrle maximizing animal health The program was developed by the National Pork Board, but veterinarians are key in the delivery of the program on farm. Since there are many factors that contribute to the amounts and types of antimicrobrals used on farm it was decided that the best way to measure program effectiveness was through measurement of changes in the attitude and behaviors of program particrpants

    Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression

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    background: There is an acute need to uncover biomarkers that reflect the molecular pathologies, underpinning prostate cancer progression and poor patient outcome. We have previously demonstrated that in prostate cancer cell lines PDE4D7 is downregulated in advanced cases of the disease. To investigate further the prognostic power of PDE4D7 expression during prostate cancer progression and assess how downregulation of this PDE isoform may affect disease outcome, we have examined PDE4D7 expression in physiologically relevant primary human samples. methods: About 1405 patient samples across 8 publically available qPCR, Affymetrix Exon 1.0 ST arrays and RNA sequencing data sets were screened for PDE4D7 expression. The TMPRSS2-ERG gene rearrangement status of patient samples was determined by transformation of the exon array and RNA seq expression data to robust z-scores followed by the application of a threshold >3 to define a positive TMPRSS2-ERG gene fusion event in a tumour sample. results: We demonstrate that PDE4D7 expression positively correlates with primary tumour development. We also show a positive association with the highly prostate cancer-specific gene rearrangement between TMPRSS2 and the ETS transcription factor family member ERG. In addition, we find that in primary TMPRSS2-ERG-positive tumours PDE4D7 expression is significantly positively correlated with low-grade disease and a reduced likelihood of progression after primary treatment. Conversely, PDE4D7 transcript levels become significantly decreased in castration resistant prostate cancer (CRPC). conclusions: We further characterise and add physiological relevance to PDE4D7 as a novel marker that is associated with the development and progression of prostate tumours. We propose that the assessment of PDE4D7 levels may provide a novel, independent predictor of post-surgical disease progression

    The Case for Learned Index Structures

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    Indexes are models: a B-Tree-Index can be seen as a model to map a key to the position of a record within a sorted array, a Hash-Index as a model to map a key to a position of a record within an unsorted array, and a BitMap-Index as a model to indicate if a data record exists or not. In this exploratory research paper, we start from this premise and posit that all existing index structures can be replaced with other types of models, including deep-learning models, which we term learned indexes. The key idea is that a model can learn the sort order or structure of lookup keys and use this signal to effectively predict the position or existence of records. We theoretically analyze under which conditions learned indexes outperform traditional index structures and describe the main challenges in designing learned index structures. Our initial results show, that by using neural nets we are able to outperform cache-optimized B-Trees by up to 70% in speed while saving an order-of-magnitude in memory over several real-world data sets. More importantly though, we believe that the idea of replacing core components of a data management system through learned models has far reaching implications for future systems designs and that this work just provides a glimpse of what might be possible
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