215 research outputs found
Status update on White-eared Night Heron Gorsachius magnificus in South China
White-eared Night Heron Gorsachius magnificus is probably the most threatened heron species in the world, and the highest priority for heron species conservation. From 1990 to 1998, there were sightings from only six localities in the wild. There are none in captivity. In 1998 a caged bird was found in a wildlife market in the city of Nanning, Guangxi Zhuang Autonomous Region, People's Republic of China. This finding prompted a 12-month survey in 1998-1999 of both markets and potential habitats in Guangxi. Several captured birds provided direct evidence of the existence of small populations in Guangxi and Guangdong Provinces. The respective habitats were surveyed in spring 2000, with emphasis on observations at dusk. The species was seen at two locations. Although some of the captured birds came from highly degraded habitat, the best sites seemed to be in areas near extensive primary forests, with streams, rice fields and marshes. The information obtained will be used to compile a detailed Action Plan designed to prevent the extinction of the species.published_or_final_versio
Prognosis of Nasopharyngeal Carcinoma in the Elderly is Worse than in Younger IndividualsâExperience of a Medical Institute
SummaryPurposeWe aimed to evaluate outcomes of the elderly (>65 years) by comparing with younger (<40 years) patients after treatments for nasopharyngeal carcinoma (NPC).Materials and methodsWe retrospectively obtained clinical data from charts for 23 older and 21 younger patients in whom NPC was diagnosed and who underwent curative managements during 2007 and 2011. Occurrence of local recurrence, distant metastasis, and death from any cause were recorded as endpoints. Cox proportional hazards regression was applied to determine age effects on survival risks after adjusting for the potential confounders.ResultsOlder patients more commonly received a diagnosis of chronic diseases than the younger patients (56.5% versus 23.8%, p = 0.036), whereas they were less likely to have received intensive treatments for NPC. After adjusting for medical history and neoadjuvant chemotherapy, older age was the only significant predictor in the study cohort for overall survival and progression-free survival. The adjusted hazard ratio (HR) for death from all causes in older patients was 6.3 (95% confidence interval [CI] = 1.3â30.2), and the adjusted HR for disease progression in older patients was 10.9 (95% CI = 2.3â50.6).ConclusionAging was the only independent prognostic risk factor in this study cohort. Medical history and treatment variations could not fully explain the difference in prognosis. Our results strengthen the need to ameliorate toxicities and improve supportive care for older patients with a diagnosis of NPC
Largeâscale changes in macrobenthic biodiversity driven by mangrove afforestation
1. Large- scale anthropogenic mangroves have been constructed in coastal regions worldwide but our understanding of their ecological effects is limited. In particu-lar, the question of whether and how anthropogenic mangroves influence biodi-versity patterns remains elusive.2. Here, we investigated the influence of large-scale anthropogenic mangroves on biodiversity patterns of mangrove macrobenthos. Specifically, we measure and seek to explain differences in species richness, abundance, assemblage composi-tion and distance-decay effect before and after the construction of anthropo-genic mangroves.3. We surveyed assemblages of gastropod, bivalve and crab species over a wide latitudinal extent (24â28°N) in subtropical China. For each, we calculated species richness, abundance, assemblage composition and distance-decay relationship before and after the construction of anthropogenic mangroves.4. After the large-scale anthropogenic mangroves, we found species richness of gas-tropods, bivalves and crabs increased by 23.81%, 100% and 20%, respectively. The distance-decay effects of gastropods and bivalves decreased by 25% and 91.43%, while that of crabs remained virtually unchanged, which mediated by in-creased dispersal rate of macrobenthos. With mangrove plantation, compositional similarity of crab and bivalve assemblages increased by 28.57% and 38.46%, sug-gesting that large-scale monospecific planting exacerbate biotic homogenization. Altogether, these results indicate that large-scale anthropogenic habitats increase the diversity of mangrove macrobenthos and change taxonomic compositions by reducing distance-decay effects and increasing dispersal rate of macrobenthos.5. Synthesis and applications. We emphasize that afforestation of coastal wetlands can drive major changes in benthonic communities. Monitoring and assessing the ecological effects of the anthropogenic habitats for the presence of functional faunas will be important in determining the future coastal restoration and main-taining economic aquaculture. Quantifying those effects in terms of regional bio-diversity composition will contribute to the management of coastal restoration to be based upon macroevidence rather than a one-sided local perspective.info:eu-repo/semantics/publishedVersio
Nanoparticles prepared from the water extract of Gusuibu (Drynaria fortunei J. Sm.) protects osteoblasts against insults and promotes cell maturation
Our previous study showed that Gusuibu (Drynaria fortunei J. Sm.) can stimulate osteoblast maturation. This study was further designed to evaluate the effects of nanoparticles prepared from the water extract of Gusuibu (WEG) on osteoblast survival and maturation. Primary osteoblasts were exposed to 1, 10, 100, and 1000 ÎŒg/mL nanoparticles of WEG (nWEG) for 24, 48, and 72 hours did not affect morphologies, viability, or apoptosis of osteoblasts. In comparison, treatment of osteoblasts with 1000 ÎŒg/mL WEG for 72 hours decreased cell viability and induced DNA fragmentation and cell apoptosis. nWEG had better antioxidant bioactivity in protecting osteoblasts from oxidative and nitrosative stress-induced apoptosis than WEG. In addition, nWEG stimulated greater osteoblast maturation than did WEG. Therefore, this study shows that WEG nanoparticles are safer to primary osteoblasts than are normal-sized products, and may promote better bone healing by protecting osteoblasts from apoptotic insults, and by promoting osteogenic maturation
A family-oriented therapy program for youths with substance abuse: long-term outcomes related to relapse and academic or social status
A family-oriented treatment program for youths with ketamine abuse and their caregivers: a pilot study in Taiwan
Natural Product Chemistry of Gorgonian Corals of Genus JunceellaâPart II
The structures, names, bioactivities, and references of 81 new secondary metabolites obtained from gorgonian corals belonging to the genus Junceella are described in this review. All compounds mentioned in this review were obtained from sea whip gorgonian corals Junceella fragilis and Junceella juncea, collected from the tropical and subtropical Indo-Pacific Ocean
Lobocrassins AâE: New Cembrane-Type Diterpenoids from the Soft Coral Lobophytum crassum
Five new cembrane-type diterpenoids, lobocrassins AâE (1â5), were isolated from the soft coral Lobophytum crassum. The structures of cembranes 1â5 were established by spectroscopic and chemical methods and by comparison of the spectral data with those of known cembrane analogues. Lobocrassin A (1) is the first cembranoid possessing an α-chloromethyl-α-hydroxy-Îł-lactone functionality and is the first chlorinated cembranoid from soft corals belonging to the genus Lobophytum. Lobocrassins B (2) and C (3) were found to be the stereoisomers of the known cembranes, 14-deoxycrassin (6) and pseudoplexaurol (7), respectively. Lobocrassin B (2) exhibited modest cytotoxicity toward K562, CCRF-CEM, Molt4, and HepG2 tumor cells and displayed significant inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils
Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae)
A new bioactive sterol glycoside, 3ÎČ-O-(3âČ,4âČ-di-O-acetyl-ÎČ-d-arabinopyranosyl) -25Ο-cholestane-3ÎČ,5α,6ÎČ,26-tetrol-26-acetate) (carijoside A, 1), was isolated from an octocoral identified as Carijoa sp. The structure of glycoside 1 was established by spectroscopic methods and by comparison with spectral data for the other known glycosides. Carijoside A (1) displayed significant inhibitory effects on superoxide anion generation and elastase release by human neutrophils and this compound exhibited moderate cytotoxicity toward DLD-1, P388D1, HL-60, and CCRF-CEM tumor cells
Cladielloides A and B: New Eunicellin-Type Diterpenoids from an Indonesian Octocoral Cladiella sp
Two new eunicellin-type diterpenoids, cladielloides A (1) and B (2), which were found to possess a 2-hydroxybutyroxy group in their structures, were isolated from an Indonesian octocoral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods. Cladielloide B (2) exhibited moderate cytotoxicity toward CCRF-CEM tumor cells and this compound displayed significant inhibitory effects on superoxide anion generation and elastase release by human neutrophils
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