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Insight into the evolution of the Tagish Lake carbonaceous chondrite by analysis of the oxygen isotopic composition of extracted water and Mössbauer spectroscopy
Analysis of oxygen isotopes in water from Tagish Lake together with Mössbauer Spectroscopy suggest some similarities to the CI group of meteorites but also suggest differences in the extent of parent body hydrothermal alteration
Pseudo-Hall effect and anisotropic magnetoresistance in a micronscale Ni80Fe20 device
The pseudo-Hall effect (PHE) and anisotropic magnetoresistance (AMR) in a micronscale Ni80Fe20, six-terminal device, fabricated by optical lithography and wet chemical etching from a high quality UHV grown 30 Angstrom Au/300 Angstrom Ni80Fe20 film, have been studied. The magnetisation reversal in different parts of the device has been measured using magneto-optical Kerr effect (MOKE), The device gives a 50% change in PHE voltage with an ultrahigh sensitivity of 7.3%Oe(-1) at room temperature. The correlation between the magnetisation, magneto-transport properties, lateral shape of the device and directions of the external applied field is discussed based on extensive MOKE, AMR and PHE results
Influence of lateral geometry on magnetoresistance and magnetisation reversal in Ni80Fe20 wires
The magnetisation reversal processes and magnetoresistance behaviour in micron-sized Ni80Fe20 wires with triangular and rectangular modulated width have been studied. The wires were fabricated by electron beam lithography and a lift-off process. A combination of magnetic force microscopy (MFM), magneto-optical Kerr effect (MOKE) and magnetoresistance (MR) measurements shows that the lateral geometry of the wires greatly influences the magnetic and transport properties. The width modulations modify not only the shape-dependent demagnetising fields, but also the current density. The correlation between the lateral geometry, the magnetic and the transport properties is discussed based on MFM, MOKE and MR results
Magnetic domain evolution in permalloy mesoscopic dots
Permalloy (Ni80Fe20) squares (30 nm thick and w mu m wide; 1 less than or equal to w less than or equal to 200 mu m) and circular disks (30 nm thick and r mu m diameter; 1 less than or equal to r less than or equal to 200 mu m) prepared on a GaAs (100) substrate were observed in both their demagnetized and remanent states by magnetic force microscopy (MFM) associated with non-contact atomic force microscopy (NC-AFM). The squares (2 less than or equal to w mu m) exhibited conventional closure domains and the corner plays a very important role in creating new walls. The circular disks, on the other hand, formed either vortex domain (5 less than or equal to r less than or equal to 20 mu m) or multi-domain (50 less than or equal to r mu m) states, The magnetization rotation is observed by MFM to change according to the size and shape of the elements, The MFM observations are supported by micromagnetic calculations which confirm the effect of the corner on the domain wall formation
Magnetization reversal in mesoscopic Ni80Fe20 wires: A magnetic domain launching device
The magnetization reversal process in mesoscopic permalloy (Ni80Fe20) wire structures has been investigated using scanning Kerr microscopy, magnetic force microscopy (MFM) and micromagnetic calculations. We find that the junction offers a site for reversed domain wall nucleation in the narrow part of the wires. As a consequence, the switching field is dominated by the domain nucleation field and the junction region initiates reversal by the wall motion following the nucleation of domains. Our results suggest the possibility of designing structures that can be used to “launch” reverse domains in narrow wires within a controlled field rang
Magnetization reversal and magnetic anisotropy in Co network nanostructures
The magnetization reversal and magnetic anisotropy in Co network structures have been studied using magneto-optic Kerr effect (MOKE). An enhancement of the coercivity is observed in the network structures and is attributed to the pinning of domain walls by the hole edges in the vicinity of which the demagnetizing field spatially varies. We find that the magnetization reversal process is dominated by the intrinsic unaxial anisotropy (2K(u)/M(s)approximate to 200 Oe) in spite of the shape anisotropy induced by the hole edges. The influence of the cross-junction on the competition between the intrinsic uniaxial anisotropy and the induced shape anisotropy is discussed using micromagnetic simulations
Suppression of the near-infrared OH night sky lines with fibre Bragg gratings - first results
The background noise between 1 and 1.8 microns in ground-based instruments is
dominated by atmospheric emission from hydroxyl molecules. We have built and
commissioned a new instrument, GNOSIS, which suppresses 103 OH doublets between
1.47 - 1.7 microns by a factor of ~1000 with a resolving power of ~10,000. We
present the first results from the commissioning of GNOSIS using the IRIS2
spectrograph at the AAT. The combined throughput of the GNOSIS fore-optics,
grating unit and relay optics is ~36 per cent, but this could be improved to
~46 per cent with a more optimal design. We measure strong suppression of the
OH lines, confirming that OH suppression with fibre Bragg gratings will be a
powerful technology for low resolution spectroscopy. The integrated OH
suppressed background between 1.5 and 1.7 microns is reduced by a factor of 9
compared to a control spectrum using the same system without suppression. The
potential of low resolution OH suppressed spectroscopy is illustrated with
example observations.
The GNOSIS background is dominated by detector dark current below 1.67
microns and by thermal emission above 1.67 microns. After subtracting these we
detect an unidentified residual interline component of ~ 860 +/ 210
ph/s/m^2/micron/arcsec^2. This component is equally bright in the suppressed
and control spectra. We have investigated the possible source of the interline
component, but were unable to discriminate between a possible instrumental
artifact and intrinsic atmospheric emission. Resolving the source of this
emission is crucial for the design of fully optimised OH suppression
spectrographs. The next generation OH suppression spectrograph will be focussed
on resolving the source of the interline component, taking advantage of better
optimisation for a FBG feed. We quantify the necessary improvements for an
optimal OH suppressing fibre spectrograph design.Comment: Accepted for publication in MNRAS. 15 pages, 18 figure
Robotic-Assisted Laparoscopic Gynecologic Procedures in a Fellowship Training Program
An early evaluation of the feasibility of training fellows in robotic surgery suggests that it is feasible to incorporate a systematic approach to robotic-assisted laparoscopic training at the onset of incorporating this technology into current practice
High glucose up-regulates ENaC and SGK1 expression in HCD-cells
Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately regulate sodium resorption in response to hyperglycaemia. However, the mechanisms by which glucose alters sodium re-uptake have not been fully characterised.
Methods: Here we present RT-PCR, western blot and immunocytochemistry data confirming mRNA and protein expression of the serum and glucocorticoid inducible kinase (SGK1) and the a conducting subunit of the epithelial sodium channel (ENaC) in a model in vitro system of the human cortical collecting duct (HCD). We examined changes in expression of these elements in response to glucose challenge, designed to mimic hyperglycaemia associated with type 2 diabetes mellitus. Changes in Na+ concentration were assessed using single-cell microfluorimetry.
Results: Incubation with glucose, the Ca2+-ionophore ionomycin and the cytokine TGF-beta 1 were all found to evoke significant and time-dependent increases in both SGK1 and alpha ENaC protein expression. These molecular changes were correlated to an increase in Na+-uptake at the single-cell level.
Conclusion: Together these data offer a potential explanation for glucose-evoked Na+-resorption and a potential contributory role of SGK1 and ENaCs in development of secondary hypertension, commonly linked to diabetic nephropathy
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