40 research outputs found

    Examining the Delivery Mode of Mental Practice in Reducing Hemiparesis: A Randomized Controlled Trial

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    Background: Mental Practice (MP) is an effective intervention to address upper extremity (UE) hemiparesis post-stroke. However, parameters for the delivery mode of MP have not been defined. Therefore, this study\u27s purpose was to define delivery mode parameters by comparing the effectiveness of audio-guided and video-guided MP. Method: Eighteen participants, \u3c 1-month post-stroke, with UE hemiparesis were randomized to a MP, repetitive task practice (RTP) or control group. The MP groups performed audio-guided or video-guided MP, 5x/week. The RTP group physically performed the functional tasks. The control group received traditional stroke rehabilitation. The Fugl-Meyer Assessment (FMA-UE) and Wolf Motor Function Test (WMFT) were used to assess change in UE hemiparesis. Results: Wilcoxon signed-rank test demonstrated audio MP increased FMA-UE scores from pretest (Mdn = 34.0, Mean = 34.0, SD =9.56) to posttest (Mdn = 49.0, Mean = 49.6, SD =7.5), p = .042, r = .64. Similar improvement in FMA-UE scores was found with traditional therapy. Audio MP decreased WMFT time, pretest (Mdn = 10.5, Mean = 49.9, SD = 59.1) to posttest (Mdn = 4.1, Mean = 3.5, SD = 1.4), p =.043, r =.63. Conclusion: Audio MP and traditional therapy appear to decrease impairment and increase the functional abilities of the UE following stroke. Video MP and RTP does not have this effect

    Stomach and colonic microbiome of wild Japanese macaques

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    Within the gastrointestinal tract, the physiochemical microenvironments are highly diversified among the different stages of food digestion. Accordingly, gut microbiome composition and function vary at different gut sites. In this study, we examine and compare the compositional and functional potential between the stomach and colonic microbiome of wild Japanese macaques (Macaca fuscata yakui) living in the evergreen forest of Yakushima Island. We find a significantly lower microbial diversity in the stomach than in the colon, possibly due to the stomach's acidic and aerobic environment, which is suboptimal for microbial survival. According to past studies, the microbial taxa enriched in the stomach are aero- and acid-tolerant. By functional prediction through PICRUSt2, we reveal that the stomach microbiome is more enriched in pathways relating to the metabolism of simple sugars. On the contrary, the colonic microbiota is more enriched with fiber-degrading microbes, such as those from Lachnospiracea, Ruminococcaceae, and Prevotella. Our study shows a clear difference in the microbiome between the stomach and colon of Japanese macaques in both composition and function. This study provides a preliminary look at the alpha diversity and taxonomic composition within the stomach microbiome of Japanese macaques, a hindgut-fermenting nonhuman primate

    Representation of international marriages and foreign wives in public discourses in Singapore from 1980s to 2000s

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    There has been an abundance of social science research on marriage migration in Singapore, among which, illustrated the negative portrayals of foreign wives in media. Building on existing social science scholarship on marriage migration, the paper aims to develop a historical perspective to the topic of marriage migration and explores public discourses about international marriages and the figure of foreign wives in Singapore from 1980s to 2000s. The scope of public discourses examined in the paper consists of the state, civil society and media like newspaper, television, and films. Using various materials including newspaper articles and publications from women’s rights organisation, Association of Women for Action and Research (AWARE), the paper argues that the public discourses portrayed the figure of foreign wives as largely problematic since the 1980s through different means such as silences and the amplification of certain negative traits. While some discourses framed foreign wives as a collective group, some nationalities have been featured more than the others, namely Chinese and Vietnamese nationals.Bachelor of Arts in Histor

    Effects of diet and age–sex class on the fecal particle size of wild Japanese macaques (Macaca fuscata yakui)

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    Fecal particle size provides important information on the feeding and digestion of herbivores. Understanding the effects of the potential proximate determinants on fecal particle size helps us interpret this widely used measurement. In folivores, previous studies found that diet composition, dietary toughness, and age–sex-related factors, such as body size and tooth wear, influenced fecal particle size. However, the role of these factors remains unknown in frugivorous and omnivorous primates. This study aims to clarify how age–sex class and diet influence fecal particle size in omnivorous Japanese macaques in Yakushima. We expected that their variable diet and differences among age–sex classes would cause variations in fecal particle size. We simultaneously documented Japanese macaques' diet, dietary toughness, and fecal particle size in the lowland area of Yakushima in the period from March 2018 to April 2019. Unexpectedly, fecal particle size showed limited differences across months and no difference among age–sex classes. Dietary toughness showed no effects on fecal particle size, while the consumption of fruits showed only a marginally significant negative effect. Our data indicate that the results of chewing were not affected by dietary toughness in our study subjects, while age–sex classes showed no difference in food comminution. This lack of variation might derive from a diet with low dietary toughness. We also found that the physical structure of preferred foods played an important role in fecal particle size variations. These results suggest that food comminution is less variable in frugivorous and omnivorous primates compared to highly specialized species (e.g., geladas). Factors other than what we examined in this study, such as food physical structure and chewing behavior, should also be taken into consideration

    Seasonal responses and host uniqueness of gut microbiome of Japanese macaques in lowland Yakushima

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    Background Changes in the gut microbial composition is an important response to cope with the seasonal fluctuations in the environment such as food availability. We examined the bacterial gut microbiome of the wild nonhuman primate, Japanese macaque (Macaca fuscata) in Yakushima over 13 months by noninvasive continuous sampling from three identified adult females. Results Dietary composition varied considerably over the study period and displayed marked shifts with the seasons. Feeding of leaves, fruits, and invertebrates were their main foods for at least one month. Diet had a significant influence on the gut microbiome. We also confirmed significant effect of host uniqueness in the gut microbiome among the three macaques. Leaf-dominated diet shaped unique gut microbiome structures where the macaques had the highest alpha diversity and their gut microbiome was enriched with Spirochaetes and Tenericutes. Diet-related differences in the putative function were detected, such as a differentially abundant urea cycle during the leaf-feeding season. Conclusion Both diet and host individuality exerted similar amounts of effect on gut microbe community composition. Major bacterial taxa showed a similar response to monthly fluctuations of fruit and invertebrate feeding, which was largely opposite to that of leaf feeding. The main constituents of fruits and invertebrates are both digestible with the enzyme of the host animals, but that of leaves is not available as an energy source without the aid of the fermentation of the gut microbiome

    Billion-pixel X-ray camera (BiPC-X)

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    The continuing improvement in quantum efficiency (above 90% for single visible photons), reduction in noise (below 1 electron per pixel), and shrink in pixel pitch (less than 1 micron) motivate billion-pixel X-ray cameras (BiPC-X) based on commercial CMOS imaging sensors. We describe BiPC-X designs and prototype construction based on flexible tiling of commercial CMOS imaging sensors with millions of pixels. Device models are given for direct detection of low energy X-rays (<< 10 keV) and indirect detection of higher energies using scintillators. Modified Birks's law is proposed for light-yield nonproportionality in scintillators as a function of X-ray energy. Single X-ray sensitivity and spatial resolution have been validated experimentally using laboratory X-ray source and the Argonne Advanced Photon Source. Possible applications include wide field-of-view (FOV) or large X-ray aperture measurements in high-temperature plasmas, the state-of-the-art synchrotron, X-ray Free Electron Laser (XFEL), and pulsed power facilities.Comment: 6 pages, 8 figure

    Fermentation Ability of Gut Microbiota of Wild Japanese Macaques in the Highland and Lowland Yakushima: In Vitro Fermentation Assay and Genetic Analyses

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    Wild Japanese macaques (Macaca fuscata Blyth) living in the highland and lowland areas of Yakushima are known to have different diets, with highland individuals consuming more leaves. We aim to clarify whether and how these differences in diet are also reflected by gut microbial composition and fermentation ability. Therefore, we conduct an in vitro fermentation assay using fresh feces from macaques as inoculum and dry leaf powder of Eurya japonica Thunb. as a substrate. Fermentation activity was higher for feces collected in the highland, as evidenced by higher gas and butyric acid production and lower pH. Genetic analysis indicated separation of highland and lowland in terms of both community structure and function of the gut microbiota. Comparison of feces and suspension after fermentation indicated that the community structure changed during fermentation, and the change was larger for lowland samples. Analysis of the 16S rRNA V3-V4 barcoding region of the gut microbiota showed that community structure was clearly clustered between the two areas. Furthermore, metagenomic analysis indicated separation by gene and pathway abundance patterns. Two pathways (glycogen biosynthesis I and D-galacturonate degradation I) were enriched in lowland samples, possibly related to the fruit-eating lifestyle in the lowland. Overall, we demonstrated that the more leaf-eating highland Japanese macaques harbor gut microbiota with higher leaf fermentation ability compared with the more fruit-eating lowland ones. Broad, non-specific taxonomic and functional gut microbiome differences suggest that this pattern may be driven by a complex interplay between many taxa and pathways rather than single functional traits
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