369 research outputs found

    ВлияниС молСкулярной массы Π»ΠΈΠ³Π½ΠΎΡΡƒΠ»ΡŒΡ„ΠΎΠ½Π°Ρ‚Π° натрия Π½Π° рСологичСскиС свойства высококонцСнтрированных суспСнзий Π±ΡƒΡ€ΠΎΠ³ΠΎ угля

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    ДослідТСно Π²ΠΏΠ»ΠΈΠ² молСкулярної маси Π»Ρ–Π³Π½ΠΎΡΡƒΠ»ΡŒΡ„ΠΎΠ½Π°Ρ‚Ρƒ Π½Π°Ρ‚Ρ€Ρ–ΡŽ Π½Π° Ρ€Π΅ΠΎΠ»ΠΎΠ³Ρ–Ρ‡Π½Ρ– властивості висококонцСнтрованих Π²ΠΎΠ΄ΠΎΠ²ΡƒΠ³Ρ–Π»ΡŒΠ½ΠΈΡ… суспСнзій Π½Π° основі Π±ΡƒΡ€ΠΎΠ³ΠΎ вугілля ΠžΠ»Π΅ΠΊΡΠ°Π½Π΄Ρ€Ρ–ΠΉΡΡŒΠΊΠΎΠ³ΠΎ Ρ€ΠΎΠ΄ΠΎΠ²ΠΈΡ‰Π°. ВстановлСно, Ρ‰ΠΎ Π½ΠΈΠ·ΡŒΠΊΠΎΠΌΠΎΠ»Π΅ΠΊΡƒΠ»ΡΡ€Π½Ρ– Ρ„Ρ€Π°ΠΊΡ†Ρ–Ρ— ΡΠΏΡ€ΠΈΡΡŽΡ‚ΡŒ Ρ€ΠΎΠ·Ρ€Ρ–Π΄ΠΆΠ΅Π½Π½ΡŽ Π²ΠΎΠ΄ΠΎΠ²ΡƒΠ³Ρ–-Π»ΡŒΠ½ΠΈΡ… суспСнзій Π° високомолСкулярні Π²ΠΈΡΡ‚ΡƒΠΏΠ°ΡŽΡ‚ΡŒ Π² Ρ€ΠΎΠ»Ρ– стабілізаторів.ИсслСдовано влияниС молСкулярной массы Π»ΠΈΠ³Π½ΠΎΡΡƒΠ»ΡŒΡ„ΠΎΠ½Π°Ρ‚ΠΎΠ² натрия Π½Π° рСологичСскиС свойства высококонцСнтрированных Π²ΠΎΠ΄ΠΎΡƒΠ³ΠΎΠ»ΡŒΠ½Ρ‹Ρ… суспСнзий Π½Π° основС Π±ΡƒΡ€ΠΎΠ³ΠΎ угля АлСксандрийского мСстороТдСния. УстановлСно, Ρ‡Ρ‚ΠΎ низкомолСкулярныС Ρ„Ρ€Π°ΠΊΡ†ΠΈΠΈ ΡΠΎΠΏΡƒΡ‚ΡΡ‚Π²ΡƒΡŽΡ‚ Ρ€Π°Π·ΠΆΠΈΠΆΠ΅Π½ΠΈΡŽ Π²ΠΎΠ΄ΠΎΡƒΠ³ΠΎΠ»ΡŒΠ½Ρ‹Ρ… суспСнзий Π° высокомолСкулярныС Π²Ρ‹ΡΡ‚ΡƒΠΏΠ°ΡŽΡ‚ Π² Ρ€ΠΎΠ»ΠΈ стабилизаторов

    The identification of critical facilities from the position of cybersecurity violation by the example of energy

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    The article describes methods for identification of critical facilities, being a significant trend in researching critical infrastructures, particularly in the energy sector. The proposed methods are focused on the investigation of the energy object state in relation to the violation of cybersecurity of its information infrastructure. The cyber threats are believed to be important contemporary threats to energy security in Russia. The proposed methods formed the basis of development information-analytical system used for monitoring of cybersecurity violations in energy sector

    Π Π΅Π³ΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹Π΅ Ρ€ΡƒΠ΄ΠΎΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΠΈΡ€ΡƒΡŽΡ‰ΠΈΠ΅ структуры Π£Ρ€Π°Π»Π°

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    One of the most challenging requirements for the next generation EUV lithography is an extremely low amount of critically sized defects on mask blanks. Fast and reliable inspection of mask blanks is still a challenge. Here we present the current status of the development of our actinic Schwarzschild objective based microscope operating in dark field with EUV discharge produced plasma source. For characterization of the microscope performance, several programmed defect structures - artificial pits and bumps were created on top of multilayer mirror (ML) surfaces and investigated both with EUV microscope and atomic force microscope (AFM). Defect size sensitivity of actinic inspection in dark field mode without resolving the defects is under study. The dependency between defect shape, size and position in relation to the ML surface and its scattering signal will be discussed. Furthermore, first results of a defect mapping algorithm are presented

    ΠžΡΠΎΠ±Π΅Π½Π½ΠΎΡΡ‚ΠΈ Π°ΠΏΠΏΠ°Ρ€Π°Ρ‚Π½ΠΎΠΉ Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ Π°Π»Π³ΠΎΡ€ΠΈΡ‚ΠΌΠΎΠ² вычислСния ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒΠ½ΠΎΠΉ суммы CRC32

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    ΠŸΡ€ΠΈΠ²Π΅Π΄Π΅Π½ΠΎ описаниС Π°ΠΏΠΏΠ°Ρ€Π°Ρ‚Π½Ρ‹Ρ… Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΉ ΠΌΠ°Ρ‚Ρ€ΠΈΡ‡Π½ΠΎΠ³ΠΎ ΠΈ Ρ‚Π°Π±Π»ΠΈΡ‡Π½ΠΎΠ³ΠΎ Π°Π»Π³ΠΎΡ€ΠΈΡ‚ΠΌΠΎΠ² вычислСния ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒΠ½ΠΎΠΉ суммы CRC32 Π½Π° ΠŸΠ›Π˜Π‘ Cyclone Ρ„ΠΈΡ€ΠΌΡ‹ Altera ΠΌΠ°ΠΊΠ΅Ρ‚Π° SDK-6.1. ΠŸΠΎΠΊΠ°Π·Π°Π½Ρ‹ особСнности Π°ΠΏΠΏΠ°Ρ€Π°Ρ‚Π½ΠΎΠΉ Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ Π½Π° ΠΏΡ€ΠΈΠΌΠ΅Ρ€Π΅ описания Π±Π»ΠΎΠΊΠΎΠ² вычислСния CRC32 ΠΈ Ρ€Π°Π±ΠΎΡ‚ΠΎΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡ‚ΡŒ спроСктированных устройств Π½Π° ΠΊΠΎΠ½ΠΊΡ€Π΅Ρ‚Π½Ρ‹Ρ… ΠΏΡ€ΠΈΠΌΠ΅Ρ€Π°Ρ…

    ИсслСдованиС систСмы Π Π—Π­ (OH)3βˆ’NH4Cl ΠΏΡ€ΠΈ Π½Π°Π³Ρ€Π΅Π²Π°Π½ΠΈΠΈ

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    The temporal evolution of neon pinch plasmas, generated in a 2kJ plasma focus device, has been investigated by x-ray spectroscopic methods for two sets of device parameters. These two sets lead to characteristic differences of the K-shell emission. Stationary models are shown to fail to explain the experimental observations even qualitatively. Transient spectra analysis shows that the characteristic differences observed can be referred to different transient modes of plasma dynamics. The spectra analysis includes beside resonance lines also dielectronic satellites and recombination continua. The results concerning the development of the plasma parameters achieved by the spectra modeling are supported by independent measurements of the time resolved K-shell emission and by optical streak images of the pinch plasma dynamics, which confirms the reliability of the transient spectroscopic analysis presented

    \u3ci\u3e Glioblastoma derived exosomes contribute to tumor immune evasion \u3c/i\u3e

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    Glioblastoma multiforme (GBM) is the most frequent and lethal primary brain tumor in adults. Despite intense biomedical research, the median survival after diagnosis is 15 months. One factor contributing to this poor prognosis is the immune protection afforded by the tumor microenvironment. Tumors have a diverse repertoire of immune-evasive techniques. One method of evasion not well explored is the release of tumor-derived exosomes. Exosomes are tiny membrane-bound vesicles of endocytic origin that contain viable mRNA and functional proteins that can affect the physiology of recipient cells. Exosome release has been reported for numerous cancer types, including GBM. Exosomes from colon cancer have been shown to carry Fas ligand (FasL) and to induce apoptosis of activated T cells. The aim of this study was to elucidate whether the same immune-evasive technique is used in GBM. GBM exosomes were isolated from the serum-free culture medium of U87 MG and U138 MG cells by using differential ultracentrifugation and were then resuspended in phosphate-buffered saline. The protein concentration of the resulting exosome pellet was determined, and subsequent exosome treatments were based on protein concentration. A3T T cells were plated at a concentration of 10,000 cells per well in 96-well plates and were treated with quantified exosome fractions or with recombinant FasL, and T cell proliferation was determined. Our data demonstrated that tumor-derived exosomes significantly inhibited the proliferation of T cells and that the cellular inhibition resulting from the exosomes was comparable to that seen with the recombinant FasL. These results suggest that targeting FasL in GBM could greatly decrease the amount of immune suppression that occurs at the tumor site

    ΠžΡ‚ΠΊΠ°Π·ΠΎΡƒΡΡ‚ΠΎΠΉΡ‡ΠΈΠ²Ρ‹ΠΉ ΠΌΠ½ΠΎΠ³ΠΎΡ„Π°Π·Π½Ρ‹ΠΉ асинхронный элСктропривод с Π½Π΅ΡΠΈΠ½ΡƒΡΠΎΠΈΠ΄Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Ρ‚ΠΎΠΊΠ°ΠΌΠΈ

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    РассмотрСн ΠΏΡ€ΠΈΠ½Ρ†ΠΈΠΏ построСния ΠΌΠ½ΠΎΠ³ΠΎΡ„Π°Π·Π½ΠΎΠ³ΠΎ асинхронного элСктропривода, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‰Π΅Π³ΠΎ ΠΏΡ€ΠΈ Π½Π΅ΠΎΠ΄Π½ΠΎΠΊΡ€Π°Ρ‚Π½Ρ‹Ρ… ΠΎΡ‚ΠΊΠ°Π·Π°Ρ… прСобразоватСля частоты ΠΈ двигатСля ΠΎΠ±Π΅ΡΠΏΠ΅Ρ‡ΠΈΡ‚ΡŒ отказоустойчивоС ΡƒΠΏΡ€Π°Π²Π»Π΅Π½ΠΈΠ΅, Π½Π° основС ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠΈΡ€ΡƒΠ΅ΠΌΡ‹Ρ… Π½Π΅ΡΠΈΠ½ΡƒΡΠΎΠΈΠ΄Π°Π»ΡŒΠ½Ρ‹Ρ… Ρ‚ΠΎΠΊΠΎΠ² с восстановлСниСм работоспособности Π·Π° счСт Π°ΠΊΡ‚ΠΈΠ²ΠΈΠ·Π°Ρ†ΠΈΠΈ Π°Π»Π³ΠΎΡ€ΠΈΡ‚ΠΌΠ° восстановлСния Π² ΡƒΠΏΡ€Π°Π²Π»ΡΡŽΡ‰Π΅ΠΌ ΠΌΠΈΠΊΡ€ΠΎΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»Π»Π΅Ρ€Π΅. ΠŸΡ€ΠΈΠ²Π΅Π΄Π΅Π½Ρ‹ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ модСлирования для Π°Π²Π°Ρ€ΠΈΠΉΠ½ΠΎΠΉ ситуации Ρ‚ΠΈΠΏΠ° "ΠΎΠ±Ρ€Ρ‹Π² Ρ„Π°Π·Ρ‹" для случая Ρ‚Ρ€Π΅Ρ…Ρ„Π°Π·Π½ΠΎΠ³ΠΎ двигатСля с частичным восстановлСниСм работоспособности асинхронного двигатСля

    Π Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ° Ρ‚Π΅ΠΏΠ»ΠΎΠΎΠ±ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ оборудования участка слива-Π½Π°Π»ΠΈΠ²Π° Π½Π΅Ρ„Ρ‚Π΅ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ² Яйского ΠΠŸΠ—

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    Π’ Π΄ΠΈΠΏΠ»ΠΎΠΌΠ½ΠΎΠΌ ΠΏΡ€ΠΎΠ΅ΠΊΡ‚Π΅ рассмотрСна установка слива-Π½Π°Π»ΠΈΠ²Π° Π½Π΅Ρ„Ρ‚Π΅ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ² Π² ΠΆΠ΅Π»Π΅Π·Π½ΠΎΠ΄ΠΎΡ€ΠΎΠΆΠ½Ρ‹Π΅ Π²Π°Π³ΠΎΠ½Ρ‹-цистСрны с Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠΎΠΉ Ρ‚Π΅ΠΏΠ»ΠΎΠΎΠ±ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ оборудования. Π’ Π΄ΠΈΠΏΠ»ΠΎΠΌΠ½ΠΎΠΌ ΠΏΡ€ΠΎΠ΅ΠΊΡ‚Π΅ рассмотрСны Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Π΅ конструкции Ρ‚Π΅ΠΏΠ»ΠΎΠΎΠ±ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ оборудования. ΠŸΡ€ΠΈΠ²Π΅Π΄Π΅Π½Ρ‹ расчСты основных тСхнологичСских, конструктивных ΠΈ прочностных ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ Π°ΠΏΠΏΠ°Ρ€Π°Ρ‚Π°. ΠŸΡ€ΠΈΠ²Π΅Π΄Π΅Π½Ρ‹ расчСты основных Ρ‚Π΅Ρ…Π½ΠΈΠΊΠΎ-экономичСских ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ, Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ Π³ΠΎΠ΄ΠΎΠ²ΠΎΠΉ Π³Ρ€Π°Ρ„ΠΈΠΊ Планово-ΠΏΡ€Π΅Π΄ΡƒΠΏΡ€Π΅Π΄ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… Ρ€Π°Π±ΠΎΡ‚, ΠΏΠΎ ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΌ Π²ΠΈΠ΄Π½ΠΎ, Ρ‡Ρ‚ΠΎ Ρ€Π°Π±ΠΎΡ‚Π° участка слива-Π½Π°Π»ΠΈΠ²Π° Π½Π΅Ρ„Ρ‚Π΅ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ² эффСктивна ΠΈ Ρ€Π΅Π½Ρ‚Π°Π±Π΅Π»ΡŒΠ½Π°.The setting of oil drain loading into railroad tanks with the development of heat transfer equipment and different constructions of the heat transfer equipment are considered in the diploma project. There are the calculations of the basic design, structural properties, technical and economic indicators in the diploma. The annual schedule of scheduled and preventative work is performed. It shows that the work of oil drain loading sector is effective and profitable. The diploma project contains the estimated explanatory note

    Π Π΅ΠΈΠ½ΠΆΠΈΠ½ΠΈΡ€ΠΈΠ½Π³ процСссов Π² ΠΎΡ‚Π΄Π΅Π»Π΅ экономики ΠΈ финансов ΠšΡ€Π°ΡΠ½ΠΎΡΡ€ΡΠΊΠΎΠ³ΠΎ ЦЀВО с использованиСм BestPractices

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    The development of new types of sophisticated soft x-ray sources requires the knowledge of their emission characteristics such as photon flux, spectral distribution, and size of the radiation source. Calibrated spectrographs for the soft x-ray region are needed to determine these properties. The components of a soft x-ray spectrograph consisting of a pinhole gold transmission grating and a charge coupled device (CCD) camera are calibrated at the radiometry laboratory of the Physikalisch-Technische Bundesanstalt using the synchrotron radiation facility BESSY. Two different kinds of CCD-based photon detectors (one thinned and back illuminated, one coated with a phosphorous layer) are compared with regard to their sensitivities in the spectral range between 50 eV and 1.7 keV. The results obtained for the thinned CCD are compared with theoretical calculations of the sensitivity
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