QR-CODE PROJECT : Towards better traceability of field sampling data

Ensuring traceability of field experimental data or laboratory sampling data to conduct reproducible research is a challenge at the present time. Between the time when geolocalized specimens (biotic or abiotic) are taken, and the time the resulting data ends up in analysis published with a study, many manual operations take place and may generate errors. The French LTSER have joined forces at the national level to propose a solution as generic as possible to this problem of monitoring of the samples and the data associated with them. Compared to existing solutions (such as Laboratory Information Management Systems), we target a robust labeling solution adapted to outdoor working conditions, with the management of stocks and movements of samples. We designed and realized a prototype tested from end to end, using an open source software, cheap Zebra printers (mobile or not) and raspberries as devices. This solution provides sufficient flexibility for the wide variety of existing protocols. In strength is the record of all contextual data associated with the samples, which constitute important parameters of the subsequent analyses. At last, not only traceability is guaranteed, but also a gain of time and a rationalization of the storage of samples that will induce a return on investment

Les dimensions du Socinianisme

Le Moal Françoise. Les dimensions du Socinianisme. In: Revue d’histoire moderne et contemporaine, tome 15 N°4, Octobre-d�cembre 1968. pp. 557-596

Long-term effects of prenatal stress and postnatal handling on age-related glucocorticoid secretion and cognitive performance: a longitudinal study in the rat

International audienceThere is growing evidence that stress during prenatal and postnatal periods of life can modify adaptive capacities in adulthood. The hypothalamo-pituitary-adrenal axis may mediate an animal's responses to perinatal stressful events and thus serve as a neurobiological substrate of the behavioural consequences of these early events. However, little is known about the long-term effects of prenatal stressors throughout the entire life of the animals. The focus of the present study was to examine the long-term influences of a prenatal and postnatal stress on glucocorticoid secretion and cognitive performance. Prenatal stress of rat dams during the last week of pregnancy and postnatal daily handling of rat pups during the first 3 weeks of life were used as stressors. The long-term effects of these manipulations were analysed using a longitudinal approach throughout the entire life of the animals, and were repeatedly tested in adulthood (4-7 months), middle age (13-16 months) and in later life (20-24 months). The study demonstrated that prenatal stress and postnatal handling induced opposite effects on both glucocorticoid secretion and cognitive performance. Prenatal stress accelerated the age-related hypothalamo-pituitary-adrenal axis dysfunctions; indeed, circulating glucocorticoids levels of prenatally stressed middle-aged animals are similar to old control ones, and also induced cognitive impairments. In contrast, postnatal handling protected from the age-related neuroendocrine and behavioural alterations. These results show that the altered glucocorticoid secretion induced by early environmental manipulations is primary to the cognitive alterations observed only later in life and could be one cause of age-related memory deficits

Introduction to the special section on the EMSLAB-Juan de Fuca experiment

Electrical properties provide a window on processes that are of great interest in understanding Earth. Elec

Hormones corticostéroïdiennes et cerveau

L’axe corticotrope est fonctionnellement relié au système nerveux central et sa physiologie dépend largement de la nature des processus mis en jeu, au niveau des régions impliquées dans les mécanismes cognitivo-comportementaux. Les fonctions d’adaptation aux événements stressants ont pour base structurale les régions impliquées dans les motivations et émotions régulant et étant régulées par les hormones dites du stress. Les conséquences à long terme de contraintes environnementales – ou mentales – répétées ou chroniques commencent à être mieux comprises et leurs effets délétères sur le système nerveux sont fortement corrélés avec une dérégulation de l’axe corticotrope, en particulier les mécanismes de rétroaction d’origine centrale. Deux exemples illustrent la pathogénie de troubles adaptatifs par dérégulation de l’axe corticotrope au cours du développement, durant les périodes pré et post-natales. A long terme, parfois après des périodes silencieuses, apparaissent des perturbations émotionnelles et cognitives, notamment chez le sujet âgé. Ces données soulèvent la question des vulnérabilités cérébrales stress-dépendantes et, conséquemment, la question de la prédiction de ces troubles

VegFrance: A French database for a better knowledge of the national vegetation

International audienc