326 research outputs found

    Open Space – a collaborative process for facilitating Tourism IT partnerships

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    The success of IT projects depends on the success of the partnerships on which they are based. However past research by the author has identified a significant rate of failure in these partnerships, predominantly due to an overly technical mindset, leading to the question: “how do we ensure that, as technological solutions are implemented within tourism, due consideration is given to human-centred issues?” The tourism partnership literature is explored for additional insights revealing that issues connected with power, participation and normative positions play a major role. The method, Open Space, is investigated for its ability to engage stakeholders in free and open debate. This paper reports on a one-day Open Space event sponsored by two major intermediaries in the UK travel industry who wanted to consult their business partners. Both the running of the event and its results reveal how Open Space has the potential to address some of the weaknesses associated with tourism partnerships

    Expanding the reflexive space: resilient young adults, institutional cultures, and cognitive schemas

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    For many U.S. young adults, being resilient to stressful events hinges on making meaning of such events and thereby minimizing their negative emotional impact. Yet why are some better able to do this than others? In this study, which uses an innovative outlier sampling strategy and linked survey and interview data, we argue that one important factor is connection to institutional cultures associated with higher education, religion/spirituality, and the military. Such cultures provide material for the development of cognitive schemas that can be adopted and applied to their stressful experiences, which include narratives of social progress, divine providence, and self‐discipline. Using a metaphor adapted from the pragmatist philosopher Charles Sanders Peirce, we argue the resulting schemas have the effect of “expanding the space” of reflexive thought, providing new cognitive material for interpreting stress and supporting resilience. Finally, we argue this framing improves in several ways on the concept of meaning making often used in stress process research.Accepted manuscrip

    Using Narrative Research and Portraiture to Inform Design Research

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    Abstract. Employing an interdisciplinary perspective, this paper addresses how narrative research and portraiture- methods originating from, and commonly used in social sciences- can be beneficial for HCI and design research communities. Narrative research takes stories as a basis for data collection and analysis, while portraiture can be used to create written narratives about interview participants. Drawing on this knowledge, we show how a focus on narrative data, and analysis of such data through portraiture, can be adopted for the specific purpose of enhancing design processes. We hope to encourage design and HCI researchers to consider adopting these methods. By drawing on an illustrative example, we show how these methods served to inform design ideas for digital crafting. Based on our experiences, we present guidelines for using narrative research and portraiture for design research, as well as discussing opportunities and strengths, and limitations and risks

    Time for curriculum reform: the case of mathematics

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    Mathematics education is rarely out of the policy spotlight in England. Over the last ten years, considerable attention has been given to improving 14-19 mathematics curriculum pathways. In this paper we consider some of the challenges of enacting curriculum change by drawing upon evidence from our evaluation of the Mathematics Pathways Project. From 2004-10 this project, which was directed by England’s Qualifications and Curriculum Authority, aimed to improve the engagement, attainment and participation rates of 14-19 year old learners of mathematics. Our particular focus is upon the temporal problems of piloting new curriculum and assessment and we draw on Lemke’s discussion of time-scales, heterochrony and the adiabatic principle to consider the interlocking and interference of various change processes

    On biocoloniality and 'respectability' in contemporary London.

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    This essay is framed by discussions on the civil unrest in British cities in 2011, the politics of austerity, the mass unemployment of the young, ‘the war on terror’ and ‘radicalisation’ and the vulnerability of the poor and ‘unrespectable’. It advances a concept of biocoloniality and explores ‘respectability’, class and transnational postcolonial urban cultures in contemporary London. The essay argues for a theorisation which can account for how a divided subject produces the effect of an undivided and self-governing ‘core self’ who ‘possesses’ distinguishing ‘biological’ ‘capacities’, ‘psychological’ attributes’ and cultural ‘characteristics’. It considers how this is accomplished through our daily practical activity such as our ‘imaginable’, ‘possible’ sexual desires, everyday practices of reflection, our bodily demeanour and bodily significations. This concept of biocoloniality is composed of two theoretical strands. In ‘on inscription and creolisation’ and in dialogue with a single respondent on ‘respectability’ and ‘beauty’, I entwine disparate theoretical threads from work on biopolitics and governmentality, racialisation, psychoanalysis and postcoloniality and performativity, sexualisation and intersectionality together. I forward a formulation of inscription that can reveal how we inscribe and sculpt our own and other bodies with different ‘capacities’ and ‘qualities’. I then tie strands of work on repetition together and advance a theorisation of reiteration. I consider how we struggle with, overcome and are defeated by ourselves as we reinscribe our own and other bodies. The essay thus considers how it is through in part our daily biocolonial practice that different bodies that are closer to and more distant from notions of the human, the un/respectable, un/desirable, ab/normal, ir/replaceable and expendable come into being and how this unsettles clear distinctions between coloniality and postcoloniality

    Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics

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    Esophageal adenocarcinoma (EAC) incidence is increasing while 5-year survival rates remain less than 15%. A lack of experimental models has hampered progress. We have generated clinically annotated EAC organoid cultures that recapitulate the morphology, genomic and transcriptomic landscape of the primary tumor including point mutations, copy number alterations and mutational signatures. Karyotyping has confirmed polyclonality reflecting the clonal architecture of the primary and subclones underwent clonal selection associated with driver gene status. Medium throughput drug sensitivity testing demonstrates the potential of targeting receptor tyrosine kinases and downstream mediators. EAC organoid cultures provide a pre-clinical tool for studies of clonal evolution and precision therapeutics
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