Influence of the nonlinearity parameter on the solar-wind sub-ion magnetic energy spectrum: FLR-Landau fluid simulations

The cascade of kinetic Alfv\'en waves (KAWs) at the sub-ion scales in the solar wind is numerically simulated using a fluid approach that retains ion and electron Landau damping, together with ion finite Larmor radius corrections. Assuming initially equal and isotropic ion and electron temperatures, and an ion beta equal to unity, different simulations are performed by varying the propagation direction and the amplitude of KAWs that are randomly driven at a transverse scale of about one fifth of the proton gyroradius in order to maintain a prescribed level of turbulent fluctuations. The resulting turbulent regimes are characterized by the nonlinearity parameter, defined as the ratio of the characteristic times of Alfv\'en wave propagation and of the transverse nonlinear dynamics. The corresponding transverse magnetic energy spectra display power laws with exponents spanning a range of values consistent with spacecraft observations. The meandering of the magnetic field lines together with the ion temperature homogenization along these lines are shown to be related to the strength of the turbulence, measured by the nonlinearity parameter. The results are interpreted in terms of a recently proposed phenomenological model where the homogenization process along field lines induced by Landau damping plays a central role

Reactor Fuel Fraction Information on the Antineutrino Anomaly

We analyzed the evolution data of the Daya Bay reactor neutrino experiment in terms of short-baseline active-sterile neutrino oscillations taking into account the theoretical uncertainties of the reactor antineutrino fluxes. We found that oscillations are disfavored at $2.6\sigma$ with respect to a suppression of the $^{235}\text{U}$ reactor antineutrino flux and at $2.5\sigma$ with respect to variations of the $^{235}\text{U}$ and $^{239}\text{Pu}$ fluxes. On the other hand, the analysis of the rates of the short-baseline reactor neutrino experiments favor active-sterile neutrino oscillations and disfavor the suppression of the $^{235}\text{U}$ flux at $3.1\sigma$ and variations of the $^{235}\text{U}$ and $^{239}\text{Pu}$ fluxes at $2.8\sigma$. We also found that both the Daya Bay evolution data and the global rate data are well-fitted with composite hypotheses including variations of the $^{235}\text{U}$ or $^{239}\text{Pu}$ fluxes in addition to active-sterile neutrino oscillations. A combined analysis of the Daya Bay evolution data and the global rate data shows a slight preference for oscillations with respect to variations of the $^{235}\text{U}$ and $^{239}\text{Pu}$ fluxes. However, the best fits of the combined data are given by the composite models, with a preference for the model with an enhancement of the $^{239}\text{Pu}$ flux and relatively large oscillations.Comment: 9 page

Influence of ion-to-electron temperature ratio on tearing instability and resulting subion-scale turbulence in a low-βe\beta_e collisionless plasma

A two-field gyrofluid model including ion finite Larmor radius (FLR) corrections, magnetic fluctuations along the ambient field and electron inertia is used to study two-dimensional reconnection in a low $\beta_e$ collisionless plasma, in a plane perpendicular to the ambient field. Both moderate and large values of the ion-to-electron temperature ratio $\tau$ are considered. The linear growth rate of the tearing instability is computed for various values of $\tau$, confirming the convergence to reduced electron magnetodynamics (REMHD) predictions in the large $\tau$ limit. Comparisons with analytical estimates in several limit cases are also presented. The nonlinear dynamics leads to a fully-developed turbulent regime that appears to be sensitive to the value of the parameter $\tau$. For $\tau = 100$, strong large-scale velocity shears trigger Kelvin-Helmholtz instability, leading to the propagation of the turbulence through the separatrices, together with the formation of eddies of size of the order of the electron skin depth. In the $\tau = 1$ regime, the vortices are significantly smaller and their accurate description requires that electron FLR effects be taken into account

A NOVEL FUSION 5'AFF3/3'BCL2 ORIGINATED FROM A t(2;18)(Q11.2-Q21.33) TRANSLOCATION IN FOLLICULAR LYMPHOMA

Follicular lymphoma is the second most frequent type of non-Hodgkin's lymphoma in adults. The basic molecular defect consists of the t(14;18)(q32;q21) translocation, juxtaposing the B-cell lymphoma protein 2 gene BCL2 to the immunoglobulin heavy chain locus IGH@, and leading to the antiapoptotic BCL2 protein overproduction. Variations in the t(14;18) are rare and can be classified into two categories: (i) simple variants, involving chromosomes 18 and 2, or 22, in which the fusion partner of BCL2 is the light-chain IGK@ or IGL@; (ii) complex variant translocations occurring among chromosomes 14, 18 and other chromosomes. We report a follicular lymphoma case showing BCL2 overexpression, detected by immunohistochemistry and real-time quantitative PCR, consequently to the formation of a novel fusion gene between the 5' of the lymphoid nuclear transcriptional activator gene AFF3 at 2q11.2, and the 3' of BCL2. This case shows evidence, for the first time, of BCL2 overexpression consequently to the fusion of BCL2 to a non-IG partner locus

nu_e Disappearance in MiniBooNE

The anomalous excess of low-energy nu_e events measured in the MiniBooNE experiment is explained through a renormalization of the absolute neutrino flux and a simultaneous disappearance of the nu_e's in the beam, which is compatible with that indicated by the results of Gallium radioactive source experiments. We present the results of the fit of MiniBooNE data (P(nu_e->nu_e) = 0.64 +0.08 -0.07) and the combined fit of MiniBooNE data and the nu_e disappearance measured in the Gallium radioactive source experiments, which gives P(nu_e->nu_e) = 0.82 +- 0.04. We show that our interpretation of the data is also compatible with an old indication in favor of nu_e disappearance found from the analysis of the results of beam-dump experiments, leading to P(nu_e->nu_e) = 0.80 +0.03 -0.04.Comment: 17 pages. Final version published in Phys. Rev. D 77, 093002 (2008

EUROnu-WP6 2010 Report

This is a summary of the work done by the Working Package 6 (Physics) of the EU project "EUROnu" during the second year of activity of the project.Comment: 82 pages, 51 eps figure

FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle

We report the identification and characterization of a novel 32-kDa protein expressed in skeletal muscle and located in the Z-disc of the sarcomere. We found that this protein binds to three other Z-disc proteins; therefore, we have-named it FATZ, gamma -filamin/ABP-L, alpha -actinin and telethonin binding protein of the Z-disc. From yeast two-hybrid experiments we are able to show that the SR3-SR4 domains of alpha -actinin 2 are required to bind the COOH-terminal region of the FATZ as does gamma -filamin/ABP-L, Furthermore, by using a glutathione S-transferase overlay assay we find that FATZ also binds telethonin. The level of FATZ protein in muscle cells increases during differentiation, being clearly detectable before the onset of myosin, Although FATZ has no known interaction domains, it would appear to be involved in a complex network of interactions with other Z-band components. On the basis of the information known about its binding partners, we could envisage a central role for FATZ in the: myofibrillogenesis, After screening our muscle expressed sequence tag data base and the public expressed sequence tag data bases, we were able to assemble two other muscle transcripts that show a high level of identity with FATZ in two different domains. Therefore, FATZ may be the first member of a small family of novel muscle proteins

Summary report of MINSIS workshop in Madrid

Recent developments on tau detection technologies and the construction of high intensity neutrino beams open the possibility of a high precision search for non-standard {\mu} - {\tau} flavour transition with neutrinos at short distances. The MINSIS - Main Injector Non-Standard Interaction Search- is a proposal under discussion to realize such precision measurement. This document contains the proceedings of the workshop which took place on 10-11 December 2009 in Madrid to discuss both the physics reach as well as the experimental requirements for this proposal.Comment: Proceedings of the MINSIS Workshop, Dec 10-11, 2009 in Madrid. 15 pages late

Prospect for Charge Current Neutrino Interactions Measurements at the CERN-PS

Tensions in several phenomenological models grew with experimental results on neutrino/antineutrino oscillations at Short-Baseline (SBL) and with the recent, carefully recomputed, antineutrino fluxes from nuclear reactors. At a refurbished SBL CERN-PS facility an experiment aimed to address the open issues has been proposed [1], based on the technology of imaging in ultra-pure cryogenic Liquid Argon (LAr). Motivated by this scenario a detailed study of the physics case was performed. We tackled specific physics models and we optimized the neutrino beam through a full simulation. Experimental aspects not fully covered by the LAr detection, i.e. the measurements of the lepton charge on event-by-event basis and their energy over a wide range, were also investigated. Indeed the muon leptons from Charged Current (CC) (anti-)neutrino interactions play an important role in disentangling different phenomenological scenarios provided their charge state is determined. Also, the study of muon appearance/disappearance can benefit of the large statistics of CC muon events from the primary neutrino beam. Results of our study are reported in detail in this proposal. We aim to design, construct and install two Spectrometers at "NEAR" and "FAR" sites of the SBL CERN-PS, compatible with the already proposed LAr detectors. Profiting of the large mass of the two Spectrometers their stand-alone performances have also been exploited.Comment: 70 pages, 38 figures. Proposal submitted to SPS-C, CER

A narrow band neutrino beam with high precision flux measurements

The ENUBET facility is a proposed narrow band neutrino beam where lepton production is monitored at single particle level in the instrumented decay tunnel. This facility addresses simultaneously the two most important challenges for the next generation of cross section experiments: a superior control of the flux and flavor composition at source and a high level of tunability and precision in the selection of the energy of the outcoming neutrinos. We report here the latest results in the development and test of the instrumentation for the decay tunnel. Special emphasis is given to irradiation tests of the photo-sensors performed at INFN-LNL and CERN in 2017 and to the first application of polysiloxane-based scintillators in high energy physics.Comment: Poster presented at NuPhys2017 (London, 20-22 December 2017). 5 pages, 2 figure