433 research outputs found

    Physical Activity, Anthropometric Measurements, Quality of Life and Menopausal Symptoms Among South-Indian Women

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    INTRODUCTION: Menopause is the period when the reproductive capacity ceases in women\u27s life. A wide range of symptoms occur as a consequence of estrogen decrease during menopause. Evidence suggests that physically active women have a better quality of life (QoL) and fewer menopausal symptoms. The aim of the study was to analyze the relationship between physical activity (PA), anthropometric measurements, QoL and menopausal symptoms. MATERIAL AND METHOD: A cross-sectional study was conducted online through WhatsApp and Facebook and via email among menopausal women (April 2021 - June 2021). In total 168 responses were received; 153 responses were included in the study based on the inclusion criteria. Participants were asked to complete the details of anthropometric measurements, the Menopause Rating Scale (MRS), the International Physical Activity Questionnaire and the Menopause-Specific Quality of Life Questionnaire (MENQOL). RESULTS: The majority of menopausal women complained of one or more symptoms in the MRS. A statistically significant difference was noted between the body mass index (BMI) and the menopausal symptoms such as irritability and depressive mood. There was an association between PA and MENQOL physical and sexual domains ( CONCLUSIONS: There was an association between PA, menopausal symptoms, BMI and MENQOL physical and sexual domains. Hence, moderate PA promotion is recommended among middle aged women to have a healthy menopausal transition

    3D Modeling and Clash Deduction of PBS-Television Center, Hawaii

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    This experimental investigation carried out on the present mostly using software in construction Industries Revit which is software of Autodesk, Revit is building information modeling software for architects, structural engineers, MEP engineers, designers and contractors developed by Autodesk. It allows users to design a building and structure and its components in 3D, annotate the model with 2D drafting elements, and access building information from the building model#39s database. Revi is 4D BIM capable with tools to plan and track various stages in the building#39s lifecycle, from concept to construction and later demolition. This Project carried on the 3D modeling of a building which includes the design of Structural, Architectural, and Plumbing modeling. After modeling of the design this modeling was Plug Inn into the Navis Work Manage. It is also Autodesk software where we can find the Clashes and check the Quantity and Quality of the materials use in the construction. BY using this Softwarersquos in this project, we can give the detailed Information of the building structure and design before the construction in a detail. Where we can control the difficulties occurs during the working progress of the building, Wastage of the Materials can be deducted, The Clashes occurs at Walls, Beams, Footings, Columns, and we can see the Clashes between Structural and Architectural Plans and also between Structural and MEP (Mechanical, Electrical, Plumbing) plans and we can get the proper exact estimation of the Building materials and time of the project

    Enriched Model of Case Based Reasoning and Neutrosophic Intelligent System for DDoS Attack Defence in Software Defined Network based Cloud

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    Software Defined Networking in Cloud paradigm is most suitable for dynamic functionality and reduces the computation complexity. The routers and switches located at the network's boundaries are managed by software-defined netwrking (SDN) using open protocols and specialised open programmable interfaces. But the security threats often degrade the performance of SDN due to its constraints of resource usage. The most sensitive components which are vulnerable to DDoS attacks are controller and control plane bandwidth. The existing conventional classification algorithms lacks in detection of new or unknown traffic packets which are malicious and results in degradation of SDN performance in cloud resources. Hence, in this paper double filtering methodology is devised to detect both known and unknown pattern of malicious packets which affects the bandwidth of the control panel and the controller. The case-based reasoning is adapted for determining the known incoming traffic patterns before entering the SDN system. It classifies the packets are normal or abnormal based on the previous information gathered. The traffic patterns which is not matched from the previous patterns is treated as indeterministic packet and it is defined more precisely using the triplet representation of Neutrosophic intelligent system. The grade of belongingness, non-belongingness and indeterminacyis used as the main factors to detect the new pattern of attacking packets more effectively. From the experimental outcomes it is proved that DDoS attack detection in SDN based cloud environment is improved by adopting CBR-NIS compared to the existing classification model

    A Movement of Mobile Sink in Wireless Sensor Network to Conserve Energy

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    Energy is the major constraint in wireless sensor network. In wireless sensor network with static mobile collector (SNSMC),static nodes located near to sink consume more energy, since the nodes relay the data collected by sensor nodes far away from the sink. The battery drained in short time. This problem is resolved by the MMC-WSN method. While simplifying the routing process, proposing an energy-efficient routing technique based on cluster based method for mobile sink is preferred. First part ,the selection of cluster head (CH) in cluster based method made periodically according to their residual energy and in second part the mobile sink moves across the sensing field and directly collects data from cluster heads and returns to back to initial site in a specific sequence based on spanning graphs. The spanning graph includes the shortest search path for the MS. Finally, a tour-planning algorithm is used on the basis of the spanning graph. An energy efficient routing technique (EFR) in WSNs among obstacles uses the shortest route. In this way, the mobile sink retrieves all detected knowledge among a given time and sends to base station which reduces the packet delay and energy-consumption and WSNs

    Control strategies for seamless transfer between the grid-connected and islanded modes of a microgrid system

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    Design of control strategies for Distributed generation systems is very important to achieve smoother transition between the grid connected and islanding modes of operation. The transition between these two modes of operation should be seamless, without any severe transients during the changeover. In this paper, two different control strategies namely inverter output current control and indirect grid current control for the seamless transfer between the modes of operation has been explored for the suitability. The design and analysis of the cascaded control loops based on Proportional Integral (PI) controller has been dealt in detail for both inverter output current control and indirect grid current control strategy. Control parameters are designed using the control system toolbox in MATLAB. A 10kW grid connected microgrid system has been designed and simulated in MATLAB/Simulink and the results are presented under grid connected operation, islanding operation and the transition between the modes considering fault condition in the grid side. The simulation studies are carried out using both the control strategies and the results are presented to validate the design methodology

    Productive performance of tomato (lycopersicon esculentum mill.) treated with coir pith based compost

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    Tomato (Lycopersicon esculentum Mill.) is an important vegetable which serves as a cash crop for the farmers of Sri Lanka. Due to high temperature, poor availability of water and improper nutrient management, the production of tomato is below the potential level. Coir pith compost (CPC) has favorable properties to be used as organic manure. Hence a pot experiment was conducted during the 'yala' season at the department of Agricultural Biology of Eastern University Sri Lanka to study the effects of CPC on the productive performance of tomato. Five treatments with recommended inorganic fertilizers (TO); farmyard manure (FYM) (Tl); CPC (T2); combination of FYM and inorganic fertilizers (T3); and combination of CPC and inorganic fertilizers (T4) were arranged in Complete Randomized Design with four replications. Performance of tomato was assessed in terms of plant height, number of leaves per plant, Leaf Area Index (LAI) and yield components such as number of fruits per plant, fruit size and fresh yield. The results revealed that the highest number of leaves and fruits per plant were recorded in T3. Mean fruit size and LAI were significantly (P< 0.05) higher in T4. Even though the highest yield was recorded in T4 it did not differ significantly (P< 0.05) with that of T3. It was noted that combined use of fertilizers either CPC and inorganic fertilizer or FYM and inorganic fertilizer has resulted in better yield (28% higher than control). Hence it could be concluded that coir pith compost can be used as an organic manure to improve the productivity of tomato cultivation

    FORMULATION AND EVALUATION OF GLIPIZIDE MICROEMULSION

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    Objective: The aim of the present study was to formulate a microemulsion for the oral delivery of Glipizide.Methods: Microemulsion systems composed of oleic acid, isopropyl myristate as oils; tween 80, span 20 and cremophor EL as surfactants; propylene glycol, isopropyl alcohol as cosurfactants were investigated as potential drug delivery vehicle for delivery for glipizide. Pseudo-ternary phase diagram of the investigated system at constant surfactant concentration and varying oil/water or oil/cosurfactant ratios was constructed at room temperature by titration method. This allowed studying structural inversion from oil-in-water to water-in–oil microemulsion. Furthermore, electrical conductivity, in vitro dissolution studies, pH, centrifugation, % transmittance, viscosity, particle size, polydispersity index, zeta potential, DSC and accelerated stability studies were conducted.Results: The results of electrical conductivity clearly indicated the structural inversion. Based on these values oil/water microemulsions were selected. The plain drug has shown only 40% of dissolution, while the drug from all the o/w microemulsions has shown&gt;90% dissolution. Based on in vitro release studies f3, f12, f22 formulations were chosen. Particle size values of f3, f12, f22 formulations are 202.4 nm, 83.3 nm, 315.3 nm respectively. Viscosity results showed that the formulations follow the Newtonian flow.Conclusion: The 3 formulations f3, f12 and f22 were successful in increasing the dissolution of glipizide in GIT and capable of sustaining the release of the drug for 8 h. From the viscosity, particle size, polydispersity index values, f12 was considered as the optimized formulation. Further, centrifugation, zeta potential and accelerated stability studies also indicated that the formulations were stable. DSC studies revealed no drug-excipient interaction in the optimized formulation. Owing to the above results microemulsion can be thus considered as a suitable oral delivery system for glipizide.Â

    Screening for pod shattering in mutant population of mungbean (Vigna radiata (L.) Wilczek)

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    Mungbean, (Vigna radiata (L.) Wilczek) occupies a unique position in Indian agriculture and has been grown under various agro-ecological conditions. It is cultivated in 1.61mha with production of 3.38MT and productivi-ty of 474kg/ha in India. Mungbean pods are thin and brittle when dry, so shattering is a major problem. The loss of seeds by pod dehiscence is one of the major reasons for low yield in mungbean; thus, reducing the frequency of pod dehiscence is an important objective in mungbean breeding. Induced mutations, have offered a single and short alternative to conventional breeding including isolation, screening, selection and testing generation after generation. In this study, variability was induced by gamma rays and Ethyl methane sulphonate (EMS) in two greengram geno-types viz., CO (Gg) 7 and NM 65. Screening for pod shattering was carried out in M2 and M3 populations of green-gram. The scoring for shattering was recorded at physiological maturity of the pod. The shattering percentage ranged from 14.56 (400 Gy) to 93.45 per cent (20 mM). A total of 100 shattering tolerant mutants were selected from field based on visual observation. These mutants were again scored under laboratory condition as per IITA method. A total of 12 mutants of CO (Gg) 7 and 10 mutants of NM 65 which were tolerant to pod shattering were identified in M2 generation and forwarded to M3 generation. These mutants were scored for pod shattering under laboratory con-dition and nine mutants viz., M26, M44, M46, M58, M70, M71, M84, M92 and M98 were found to be tolerant in M3 generation. This study on identification and screening of the mutants tolerant to pod shattering with high yielding potential will help to increase the production of the pods to a greater extent

    A Study on Thyroid Profile and Its Prognostic Value in Patients Presenting with ST Elevation Myocardial Infarction

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    BACKGROUND AND OBJECTIVES: The cardiovascular system and the thyroid gland are linked to each other at multiple ways and in many ways. Hypothyroidism and hyperthyroidism are both associated with an increased risk of coronary artery disease. The sick euthyroid state or the low free T3 state is characterised by a normal level of TSH, normal free T4, a reduced free T3 and elevated reverse T3.This state is usually seen when the patient suffers from any serious illness. This study is done to analyse the effects of the sick euthyroid state on the outcome of patients admitted with ST elevation Myocardial infarction. METHODS: 75 patients admitted at Government Rajaji Hospital with ST elevation Myocardial Infarction in the period between September 2013 and August 2014 were included in the study. ST elevation myocardial infarction was diagnosed with the help of history, clinical examination and a 12-lead ECG. Thyroid profile was done for all the 75 patients at the time of admission. Patients with prior history of any endocrine disorder (excluding diabetes mellitus), chronic kidney disease, chronic liver disease, oral contraceptive use, malignancy were excluded from the study. The study population was divided into 3 groups based on the thyroid profile- those with a normal thyroid profile, those with a sick euthyroid state and hypothyroid patients. All 3 groups were followed up till discharge or death and the incidence of MACE (major adverse cardiac events-cardiac failure, ventricular arrhythmias and death) was studied. The sick euthyroid group and the normal thyroid profile groups were compared in terms of in-hospital short term outcome. RESULTS: All the patients were followed up till discharge or death. Out of the 75 patients included in the study, 52 had a normal thyroid status, 8 were hypothyroid and 15 had a sick euthyroid state. Cardiac failure (66.67%, p<0.0001), ventricular arrhythmias (33.33%, p<0.012) and death (75%, p<0.0002) were found to occur more frequently in the sick euthyroid group. The incidence of MACE was 80% in the sick euthyroid group (12 out of 15 patients) with a p value of <0.0001. INTERPRETATION AND CONCLUSION: Patients with ST elevation Myocardial Infarction who have a sick euthyroid state at the time of presentation have a poor prognosis. They have a higher incidence of mortality, cardiac failure and ventricular arrhythmias

    Clinical and Microbiological Evaluation of One Stage Full Mouth Debridement in the Treatment of Chronic Periodontitis

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    Lavanya N Maheswari Rajendran 127 BACKGROUND : Periodontitis is an inflammatory disease of bacterial origin that results in the progressive destruction of the tissues that support the teeth. The gram-negative asaccharolytic bacterium Porphyromonas gingivalis, contributes to disease by paving way to a dysbiotic state. Real time polymerase chain reaction is a rapid and sensitive method for the quantitative detection of bacterial gene expression. Supra and subgingival debridement results in the mechanical disruption of the plaque biofilm and remains the “gold standard” modality used for periodontal treatment. The conventional non-surgical therapy is performed on a quadrant basis with weekly intervals. This time interval may result in re-colonisation by the bacteria of the instrumented pockets and impair healing. A relatively new treatment modality, full-mouth debridement, has a significant impact on periodontal practice, needs to be a proven benefit for patients. AIM : The aim of this study is to evaluate the clinical and microbiological outcomes of one-stage full-mouth debridement in the treatment of chronic periodontitis. MATERIALS AND METHODS : In this study 20 subjects have undergone full mouth scaling and root planing within 24 hours without adjuvant use of chlorhexidine. The clinical parameters plaque index, sulcus bleeding index, probing pocket depth and clinical attachment level were monitored at baseline; six weeks, three months and six months post treatment. Furthermore microbial analysis of the subgingival plaque sample was done by real time polymerase chain reaction at baseline; six weeks and six months post treatment. RESULTS : One stage full mouth debridement treatment provided continuous clinical improvement during the experimental period, which reached peak levels at six months. The plaque scores significantly reduced from 2.49±0.56 to 0.97±0.21 (p0.05). CONCLUSION : Within the limits of present study, it can be concluded that full mouth debridement without adjuvant use of chlorhexidine was effective in improving the clinical as well as microbiological parameters in the treatment of chronic periodontitis. However, in future, long term clinical studies monitoring clinical, microbiological and immunological changes in large number of samples will be needed
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