What senior academics can do to support reproducible and open research: a short, three-step guide

Increasingly, policies are being introduced to reward and recognise open research practices, while the adoption of such practices into research routines is being facilitated by many grassroots initiatives. However, despite this widespread endorsement and support, open research is yet to be widely adopted, with early career researchers being the notable exception. For open research to become the norm, initiatives should engage academics from all career stages, particularly senior academics (namely senior lecturers, readers, professors) given their routine involvement in determining the quality of research. Senior academics, however, face unique challenges in implementing policy change and supporting grassroots initiatives. Given that - like all researchers - senior academics are in part motivated by self-interest, this paper lays out three feasible steps that senior academics can take to improve the quality and productivity of their research, that also serve to engender open research. These steps include a) change hiring criteria, b) change how scholarly outputs are credited, and c) change to funding and publishing with open research. The guidance we provide is accompanied by live, crowd-sourced material for further reading

Maternal Prenatal Stress Is Associated With Altered Uncinate Fasciculus Microstructure in Premature Neonates

BACKGROUND: Maternal prenatal stress exposure (PNSE) increases risk for adverse psychiatric and behavioral outcomes in offspring. The biological basis for this elevated risk is poorly understood but may involve alterations to the neurodevelopmental trajectory of white matter tracts within the limbic system, particularly the uncinate fasciculus. Additionally, preterm birth is associated with both impaired white matter development and adverse developmental outcomes. In this study we hypothesized that higher maternal PNSE was associated with altered uncinate fasciculus microstructure in offspring. METHODS: In this study, 251 preterm infants (132 male, 119 female) (median gestational age = 30.29 weeks [range, 23.57-32.86 weeks]) underwent brain magnetic resonance imaging including diffusion-weighted imaging around term-equivalent age (median = 42.43 weeks [range, 37.86-45.71 weeks]). Measures of white matter microstructure were calculated for the uncinate fasciculus and the inferior longitudinal fasciculus, a control tract that we hypothesized was not associated with maternal PNSE. Multiple regressions were used to investigate the relationship among maternal trait anxiety scores, stressful life events, and white matter microstructure indices in the neonatal brain. RESULTS: Adjusting for gestational age at birth, postmenstrual age at scan, maternal age, socioeconomic status, sex, and number of days on parenteral nutrition, higher stressful life events scores were associated with higher axial diffusivity (β = .177, q = .007), radial diffusivity (β = .133, q = .026), and mean diffusivity (β = .149, q = .012) in the left uncinate fasciculus, and higher axial diffusivity (β = .142, q = .026) in the right uncinate fasciculus. CONCLUSIONS: These findings suggest that PNSE is associated with altered development of specific frontolimbic pathways in preterm neonates as early as term-equivalent age

Navigating Open Science as Early Career Feminist Researchers

Open science aims to improve the rigor, robustness, and reproducibility of psychological research. Despite resistance from some academics, the open science movement has been championed by some early career researchers, who have proposed innovative new tools and methods to promote and employ open research principles. Feminist early career researchers have much to contribute to this emerging way of doing research. However, they face unique barriers, which may prohibit their full engagement with the open science movement. We, ten feminist early career researchers in psychology, from a diverse range of academic and personal backgrounds, explore open science through a feminist lens, to consider how voice and power may be negotiated in unique ways for early career researchers. Taking a critical and intersectional approach, we discuss how feminist early career research may be complemented or challenged by shifts towards open science. We also propose how early career researchers can act as grassroots changemakers within the context of academic precarity. We identify ways in which open science can benefit from feminist epistemology and end with envisaging a future for feminist early career researchers who wish to engage with open science practices in their own research

Centering inclusivity in the design of online conferences: An OHBM-Open Science perspective

As the global health crisis unfolded, many academic conferences moved online in 2020. This move has been hailed as a positive step towards inclusivity in its attenuation of economic, physical, and legal barriers and effectively enabled many individuals from groups that have traditionally been underrepresented to join and participate. A number of studies have outlined how moving online made it possible to gather a more global community and has increased opportunities for individuals with various constraints, e.g., caregiving responsibilities. Yet, the mere existence of online conferences is no guarantee that everyone can attend and participate meaningfully. In fact, many elements of an online conference are still significant barriers to truly diverse participation: the tools used can be inaccessible for some individuals; the scheduling choices can favour some geographical locations; the set-up of the conference can provide more visibility to well-established researchers and reduce opportunities for early-career researchers. While acknowledging the benefits of an online setting, especially for individuals who have traditionally been underrepresented or excluded, we recognize that fostering social justice requires inclusivity to actively be centered in every aspect of online conference design. Here, we draw from the literature and from our own experiences to identify practices that purposefully encourage a diverse community to attend, participate in, and lead online conferences. Reflecting on how to design more inclusive online events is especially important as multiple scientific organizations have announced that they will continue offering an online version of their event when in-person conferences can resume

The factor structure of the Edinburgh Postnatal Depression Scale among perinatal high-risk and community samples in London

Timely and accurate detection of perinatal mental health problems is essential for the wellbeing of both mother and child. Growing evidence has suggested that the Edinburgh Postnatal Depression Scale (EPDS) is not a unidimensional measure of perinatal depression, but can be used to screen for anxiety disorders. We aimed to assess the factor structure of the EPDS in 3 different groups of women: n = 266 pregnant women at high-risk of depression (“Perinatal Stress Study”), n = 471 pregnant women from a community sample, and n = 637 early postnatal women from a community sample (“developing Human Connectome Project”). Exploratory factor analysis (40% of each sample) and confirmatory factor analysis (60% of each sample) were performed. The relationship between EPDS scores and history of mental health concerns was investigated. Results suggested that a 3-factor model (depression, anxiety, and anhedonia) is the most appropriate across groups. The anxiety subscale (EPDS-3A) emerged consistently and was related to maternal history of anxiety disorders in the prenatal sample (W = 6861, p < 0.001). EPDS total score was related to history of mental health problems in both the prenatal (W = 12,185, p < 0.001) and postnatal samples (W = 30,044, p < 0.001). In both high-risk and community samples in the perinatal period, the EPDS appears to consist of depression, anxiety, and anhedonia subscales. A better understanding of the multifactorial structure of the EPDS can inform diagnosis and management of women in the prenatal and postnatal period. Further research is required to validate the EPDS-3A as a screening tool for anxiety

Neural responses to food stimuli among individuals with eating and weight disorders: a systematic review of event-related potentials

A systematic review was conducted to investigate event-related potentials (ERPs) in response to food and non-food stimuli among individuals with eating and weight disorders. Limiting the search to studies that have analysed ERPs relating to motivated attention and inhibitory control, 19 research papers were extracted from a systematic search in PubMed, Ovid, and Web of Science (2000–2018). An enhanced attentional bias towards food over non-food images (as indexed by P3(00) and LPP amplitudes) was evident for all populations. Individuals with binge eating disorder showed an enhanced attentional response to food cues compared to healthy controls. Inhibitory control-related ERP components (N2(00) and P3a) increased during food-specific no-go trials, but did not differentiate overweight from ‘healthy’ weight groups. The N2 amplitude to food pictures were positively correlated with caloric intake and food craving among individuals with obesity and binge eating disorder, respectively, while P3(00) was sensitive to hunger levels among overweight and obese females. The heterogeneity of stimuli/paradigms adopted, component timescales extracted, ERPs analysed, and data presented has challenged this review’s ability to produce a robust synthesis of results. Some recommendations for future research are discussed

Bridge-building between communities: Imagining the future of biomedical autism research

A paradigm shift of research culture is required to ease perceived tensions between autistic people and the biomedical research community. As a group of autistic and non-autistic scientists and stakeholders, we contend that through participatory research we can reject a deficit-based conceptualisation of autism whilst building a shared vision for a neurodiversity-affirmative biomedical research paradigm

Awareness of and engagement with Open Research behaviours: Development of the Brief Open Research Survey (BORS) with the UK Reproducibility Network

Objectives:A need for Open Research practices exists, yet there remains a lack of validated questionnaires to assess Open Research practices. The study aimed to develop a brief (<5 minutes), standardised questionnaire to measure Open Research awareness and engagement across UK institutions. Methods: The Brief Open Research Survey (BORS) was developed in six steps: 1) a scoping exercise collated previous questionnaires on Open Research, 2) a brief questionnaire was developed, 3) peer-reviewed, 4) piloted, 5) revised,and 6) the final questionnaire was distributed across UK Reproducibility Network (UKRN) local networks. Results: Respondents across thirty-five UKRN local networks participated (n = 1,274). Respondents were most aware of Open Access publications (94.1%) and also used them the most (76.5%). They were least aware of Registered Reports (38.1%) and also used them the least (8.3%). Respondents reported that incentives (51%), dedicated funding (46.2%), and recognition in promotion and recruitment criteria (39.6%) would help them embed Open Research. Conclusion: Although various Open Research initiatives exist, there remains a disconnect between awareness and implementation. Support from funders and institutions is required to increase Open Research. The Brief Open Research Survey can be used to track uptake over time and adapted to measure Open Research globally