Wissenschaft des Judentums: An International Digital Collection

The purpose of this project is to create a complete digital collection of the historic resources of the Wissenschaft des Judentums by enriching the unique Wissenschaft collection of the Frankfurt University Library with digital facsimiles of missing titles housed at the Center, and augmenting the Center’s growing digital collections. The Frankfurt University Library estimates that it is missing about 25% of the 11,000 titles that once constituted its world renowned collection of Wissenschaft des Judentums. The Center has identified approximately 1,000 (40%) of these missing books within the holdings of its partner organizations

Timing and determinants of age at menarche in low-income and middle-income countries

Introduction: Understanding the timing and determinants of age at menarche is key to determining potential linkages between onset of puberty and health outcomes from a lifecourse perspective. Yet, we have little information in low- and middle-income countries (LMICs) mainly due to lack of data. The aim of this study is to analyse trends in the timing and the determinants of menarche in LMICs. Methods: Using 16 World Fertility Surveys and 28 Demographic and Health Surveys (DHS) from 27 countries, we analyse cohort trends and use fixed-effects models for DHS surveys to investigate socio-demographic and regional effects in the timing of age at menarche. Results: Trends of the mean age at menarche across time within and between countries show a declining or stalling path. Results of the determinants modelling show the relationship with wealth changes over time although not consistently across countries. We see a shift from poorer women having earlier menarche in earlier surveys to richer women having earlier menarche in later surveys in Indonesia, the Philippines and Yemen, whilst in Egypt the reverse pattern is evident. Conclusions: There is a considerable gap in both literature and data on menarche. We see a trend which is declining rapidly (from 14.66 to 12.86 years for the 1932 and 2002 cohorts respectively), possibly at a faster pace than high income countries and with a strong link to socio-economic status. This study calls for menarche questions to be included in more nationally-representative surveys and greater use of existing data because of its impact on life-course health in fast ageing settings. Further studies will need to investigate further the use of the age at menarche as an indicator of global health

Cacao agroforestry systems do not increase pest and disease incidence compared with monocultures under good cultural management practices

Pests and diseases threaten cacao production worldwide. Agroforestry systems are traditionally seen by farmers as one of the causes of increased pest and disease incidence, in contrast with full-sun monocultures. Cultural management practices - e.g. regular tree pruning, frequent pod harvest, regular removal of infested pods, weed management - have been reported to be crucial for pest and disease management. We performed two experiments for the purpose of assessing the effect of (i) different cacao production systems, and (ii) the frequency of harvest and removal of infested pods on the incidence of pests and diseases and on the cacao yield. The first experiment was performed in a long-term system comparison trial in Bolivia, where data on pest and disease incidence were recorded for three years in five production systems: two monocultures and two agroforestry system under organic and conventional farming, and one successional agroforestry system, i.e. a high tree density multi-strata system. Pest and disease management did not differ between systems and relied on cultural management practices. Overall, the incidence of pests and diseases did not differ between production systems, which indicated they were not the driver of yield differences between them. Across production systems, only 14% of the pods were affected by pests and diseases; 70% of these were affected by frosty pod rot. More than 80% of the pods infected by frosty pod rot were removed before the sporulation phase. In the second experiment, the effects of the frequency of harvest and removal of infected pods - every 15 days versus every 25 days - on pest and disease incidence and yield were tested in four farmers’ fields. Fortnightly harvest and diseased pod removal significantly decreased disease incidence and increased cacao yield, by 25% and 46% respectively. Our results show that cacao agroforestry systems do not increase pest and disease incidence compared with monocultures when good cultural management practices are implemented, which, in turn, can increase the productivity of the cacao plantations

Urban Planning and Sustainable Storm Water Management: Gaps and Potential for Integration for Climate Adaptation Strategies

While climate change urges cities to define appropriate strategies for climate adaptation, urban planning practices are still unable to encompass a broader understanding of hydraulic hazards and to exploit the mitigation potential of nature-based solutions (NBS) for stormwater management. This inability is particularly deep in the Italian context, where the integration of climate adaptation strategies within urban planning is very limited; thus, one of the planner's overriding needs is to determine where NBS can be most effective. The objective of this paper is to identify key drivers and tools for the introduction of hydrological resilience assessments and sustainable storm water management in urban planning practices, as a contribution to climate adaptation strategies. Through a case study in the city of Bari, the paper proposes a method for identifying the most suitable urban areas for implementing NBS, i.e., areas where NBS are able to intercept runoff. On the other hand, the same approach allows one to evaluate in advance the impact of urban planning choices, or rather of the planned land use change. Finally, the planning tools that may favor the adoption of a NBS approach in urban planning are analyzed, with particular reference to the territorial landscape plan of the Apulia region and urban regeneration plans

Depends who’s asking: interviewer effects in Demographic and Health Surveys abortion data

Responses to survey questions about abortion are affected by a wide range of factors including stigma, fear and cultural norms. However, we know little about how interviewers might affect responses to survey questions on abortion. The aim of this study is to assess how interviewers affect the probability of women reporting past abortions in nationally representative household surveys (Demographic and Health Surveys – DHS). We use cross- classified random intercepts at the level of the interviewer and the sampling cluster in a Bayesian framework to analyse the impact of interviewers on the probability of reporting past abortions in twenty-two DHS conducted worldwide. Household surveys are the only available data we can use to study the determinants and pathways of abortion in detail and in a representative manner. Our analyses are motivated by improving our understanding of the reliability of these data. Results show an interviewer effect accounting for between 0.2% and 50% of the variance in the odds of a woman reporting ever having an abortion, after controlling for women’s demographic characteristics. In contrast, sampling cluster effects are much lower in magnitude. Our findings suggest the need for additional effort in assessing the causes of abortion underreporting in household surveys, including interviewers’ skills and characteristics. This study also has important implications for improving the collection of other sensitive demographic data (e.g.: gender-based violence and sexual health). Data quality of responses to sensitive questions could be improved with more attention to interviewers – their recruitment, training and characteristics. Future analyses will need to account for the role of interviewer to more fully understand the possible data biases

Secular trends in premature and early menopause in low-income and middle-income countries

BACKGROUND: While secular trends in high-income countries show an increase in the mean age at menopause, it is unclear if there is a similar pattern in low-income and middle-income countries (LMICs), where women's exposure to biological, environmental and lifestyle determinants of menopause may differ. Premature (before age 40 years) and early (ages 40-44 years) menopause could have negative repercussions on later life health outcomes which in ageing societies could mean further stress on low-resource health systems. An evaluation of such trends in LMICs has been hampered by the suitability, quality and comparability of data from these countries. METHODS: Using 302 standardised household surveys from 1986 to 2019, we estimate trends and CIs using bootstrapping in the prevalence of premature and early menopause in 76 LMICs. We also developed a summary measure of age at menopause for women who experience menopause before the age of 50 years based on demographic estimation methods that can be used to measure menopausal status in surveys with truncated data. RESULTS: Trends indicate an increasing prevalence of early and premature menopause in LMICs, in particular in sub-Saharan Africa and South/Southeast Asia. These regions also see a suggested decline of the mean age at menopause with greater variation across continents. CONCLUSIONS: This study enables the analysis of menopause timing by exploiting data generally used for the study of fertility by methodologically allowing the use of truncated data. Findings show a clear increase in prevalence of premature and early menopause in the regions with the highest fertility with possible consequences for later life health. They also show a different trend compared with high-income regions, confirming a lack of generalisability and the importance of accounting for nutritional and health transitions at the local level. This study calls for further data and research on menopause on a global scale

RdDM pathway components differentially modulate Tobamovirus symptom development

Small RNAs (sRNAs) are important molecules for gene regulation in plants and play an essential role in plantpathogen interactions. Researchers have evaluated the relationship between viral infections as well as the endogenous accumulation of sRNAs and the transcriptional changes associated with the production of symptoms, but little is known about a possible direct role of epigenetics, mediated by 24-nt sRNAs, in the induction of these symptoms. Using diferent RNA directed DNA methylation (RdDM) pathway mutants and a triple demethylase mutant; here we demonstrate that the disruption of RdDM pathway during viral infection produce alterations in the plant transcriptome and in consequence changes in plant symptoms. This study represents the initial step in exposing that DNA methylation directed by endogenous sRNAs has an important role, uncoupled to defense, in the production of symptoms associated with plant-virus interactions.Fil: Leone, Melisa. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; Argentina. Ministerio de Ciencia. Tecnología e Innovación Productiva. Agencia Nacional de Promoción Científica y Tecnológica; ArgentinaFil: Zavallo, Diego. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Venturuzzi, Andrea Laura. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Asurmendi, Sebastian. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; Argentin