Gamification in the classroom for english language vocabulary acquisition and reinforcement

The main objective of this Final Degree Project is to demonstrate the usefulness of gamified tools in English vocabulary acquisition. These benefits of the use of gamification in English language learning are discussed from two different points of view: teacher and student. In order to reach this objective, a methodology has been proposed to research these advantages of gamification in this aspect of the English language mentioned above. This investigation project employs Socrative, a tool introduced to the students of a language academy. Its innovation for the students and its appropriate planning contributed to successfully obtaining the results of the methodologyEl objetivo principal de este Trabajo de Fin de Grado (TFG) es demostrar la utilidad de las herramientas gamificadas en la adquisición de vocabulario en lengua inglesa. Estos beneficios de la utilización de la gamificación en el aprendizaje de la lengua inglesa se analizan desde dos puntos de vista diferentes: profesor y estudiante. Para poder lograr este objetivo, se ha propuesto una metodología para investigar estas ventajas de la gamificación sobre este aspecto de la lengua inglesa mencionado previamente. Este proyecto de investigación se lleva a cabo con Socrative, una herramienta presentada a los estudiantes de una academia de idiomas. Su novedad y planificación apropiada han contribuido a la obtención con éxito de los resultados metodológicosDepartamento de Filología InglesaGrado en Estudios Inglese

Investigación y análisis de las masillas de relleno para la reintegración de lagunas cerámicas arqueológicas

Una de las características más comunes en los objetos cerámicos arqueológicos recuperados son las lagunas. Es por ello que de entre las distintas fases que intervienen en la restauración de cerámica arqueológica la reintegración formal sea una de las más importantes, aportando estabilidad y proporcionándole una correcta legibilidad a la pieza. A lo largo de la historia y en la actualidad se han venido empleando variados materiales para la reposición de faltantes en cerámica arqueológica. En la actualidad la investigación de nuevos materiales ofrece al campo de la restauración innumerables productos, siendo los tradicionales poco a poco sustituidos. Esta tesis plantea el estudio de las masillas empleadas en la reposición de faltantes en cerámica arqueológica desde la visión del comportamiento a corto, medio y largo plazo. La tesis se divide en tres partes muy diferenciadas a la vez que complementarias entre sí: un primer bloque donde se realiza una revisión histórica sobre los tratamientos de conservación de cerámica arqueológica. Un segundo bloque donde se ahonda en los criterios, procesos y materiales empleados a lo largo de la historia en los tratamientos de restauración, en concreto el tratamiento de lagunas. Y un tercer bloque experimental donde se expone la metodología de la investigación y los resultados obtenidos tras los diversos ensayos de envejecimientos a los que se han expuesto las distintas masillas experimentadas.Lastras Pérez, M. (2007). Investigación y análisis de las masillas de relleno para la reintegración de lagunas cerámicas arqueológicas [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/11224Palanci

Estudio comparativo del splicing alternativo del gen NCR3 en diferentes especies de mamíferos y sus posibles implicaciones funcionales

Tesis doctoral inédita. Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular. Fecha de lectura: 13-12-2013Alternative splicing (AS) is a major source of transcriptome and proteome diversity in higher eukaryotes allowing the generation of several structurally and functionally distinct mRNAs and protein isoforms from a single gene. Differential AS variants expression has been implicated in tissue and cellular differentiation, which in an evolutionary context could account for the phenotypic divergence of mammals that share a common repertoire of genes. On the other hand, the miss-regulation of AS is one of the mayor sources of human disease. However, there are not many detailed comparative analyses showing the alternative splice forms generated from particular genes among different organisms. The work presented here is a deep study of the splice variants expressed by the “Natural Cytotoxicity Receptor 3” (NCR3) gene and its comparative analysis among 13 mammals. NCR3 is a member of the NCR family, which represents the major NK cells triggering receptors. It has been involved in the recognition and killing of tumoral and infected cells, and in the maturation of dendritic cells. By using a combination of nested RT-PCR and RNA-seq analysis, it was possible to detect the expression of several NCR3 transcripts in all the analysed mammalian species, except in Mus musculus, where NCR3 is a pseudogen. It was observed an increase in the number of coding variants in primates, mainly by the internal splicing of exon 2 and the presence of exons 4II and 4III, which are only expressed in higher primates (Hominoidea). In contrast, the diversity of non-coding variants is similar among all analysed species, although there are some conserved ones, which could have a potential regulatory role. The nine human splice variants, six coding and three non-coding, were only detected at high expression levels in immune-related tissues, being the coding A, B y C the most abundant ones. The predicted human protein isoforms are potential transmembrane type I receptors, which extracellular domains are predicted to be Immunoglobulin type V (IgV) or type C (IgC). The interaction of these potential NCR3 extracellular domains with the ligand B7-H6 was analysed using flow citometry assays. Firstly, they were over-expressed in insect cells finding that defective glycosylation avoids binding. In a second approach, it was used a mammalian system detecting only specific binding of IgV domain to B7H6, indicating that B7H6 is not a ligand for IgC containing isoforms. In conclusion, all the presented data suggest a potential role of AS in the NCR3 functions and immune system regulation and evolution

Toward large-scale access-transistor-free memristive crossbars

Abstract — Memristive crossbars have been shown to be excel-lent candidates for building an ultra-dense memory system be-cause a per-cell access-transistor may no longer be necessary. However, the elimination of the access-transistor introduces sev-eral parasitic effects due to the existence of partially-selected de-vices during memory accesses, which could limit the scalability of access-transistor-free (ATF) memristive crossbars. In this paper we discuss these challenges in detail and describe some solutions addressing these challenges at multiple levels of design abstrac-tion. I