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Treatment response in child anxiety is differentially related to the form of maternal anxiety disorder
An examination was made of the extent to which maternal anxiety predicted response to treatment of children presenting with an anxiety disorder. In a sample of 55 children referred to a local NHS CAMH service for treatment of an anxiety disorder, systematic mental state interview assessment was made of both mothers and children, and both completed self-report questionnaires to assess aspects of anxiety, both immediately before the children received treatment and following treatment. Children of mothers with anxiety disorder overall responded less well to treatment than children of mothers with no anxiety disorder. There was some diagnostic specificity in this in that children of mothers with GAD did as well in treatment as children whose mothers had no anxiety, whereas children of mothers with social phobia did poorly. The outcome for children with anxiety appears to be related to the presence and nature of maternal anxiety. It would seem prudent that treatment of children with anxiety involves assessment of maternal anxiety. It is important to establish in systematic investigation whether treatment of maternal anxiety improves the outcome for child anxiety
Himantura lobistoma, a new whipray (Rajiformes: Dasyatidae) from Borneo, with comments on the status of Dasyatis microphthalmus
A new long-snouted whipray, Himantura lobistoma, is described on the basis of seven specimens collected from the southeastern sector of the South China Sea, off western Borneo. It belongs to a subgroup of Himantura species provisionally defined herein as the “uarnacoides” complex that includes five nominal species: H. chaophraya, H. granulata, H. hortlei, H. pastinacoides, and H. uarnacoides. These whiprays all have a similar lateral disc shape (i.e., pectoral-fin apices broadly rounded rather than narrowly rounded or angular), a plain colouration (i.e., usually uniform light to dark brown dorsally, and pale or whitish ventrally with or without a dark margin), a long and slender whiplike tail, and plate like denticles in a broad dorsal band in adults. Himantura lobistoma can be distinguished from the superficially similar H. hortlei by its highly protrusible mouth and pelvic girdle with prominent lateral prepelvic processes. It differs from other members of the “uarnacoides” complex by a combination of internal and external morphological characteristics (e.g., having an extremely elongate snout and very small eyes). Another long-snouted stingray from the region, Dasyatis microphthalmus Chen, inadequately described and known only from the lost holotype, is considered a nomen dubium. It had been assigned to Himantura based on the absence of an obvious ventral cutaneous tail fold but may be conspecific with D. acutirostra
Estudio taxonómico de Squalus megalops (Macleay, 1881) y Squalus blainvillei (Risso, 1827) (Chondrichthyes: Squalidae) en aguas de Túnez (Mediterráneo central)
Two species of spurdog of the genus Squalus occur in the Gulf of Gabès (southern Tunisia, central Mediterranean): the longnose spurdog Squalus blainvillei (Risso, 1827) and a short-snout spurdog of the Squalus megalops-cubensis group. Morphometric and meristic data as well as a genetic analyses (DNA inter-simple sequence repeat markers and molecular barcoding methods) support the assignation of this short-snout spurdog to Squalus megalops (Macleay, 1881). Squalus megalops occurs commonly in temperate and tropical Australian waters, and is also thought to occur in the eastern Atlantic, southern Indian Ocean and western North Pacific although these records need to be confirmed. Our study confirms that it occurs in the Mediterranean Sea. Populations of both S. blainvillei and S. megalops are described based on Tunisian material.En el golfo de Gabès (sur de TĂşnez, Mediterráneo central) se encuentran dos especies del gĂ©nero Squalus: el galludo Squalus blainvillei (Risso, 1827) y otra de morro más corto perteneciente al grupo Squalus megalops-cubensis. Los datos morfomĂ©tricos y merĂsticos junto con el análisis genĂ©tico (ADN Inter Simple Sequence Repeats markers y mĂ©todos moleculares Barcoding) apoyan la identificaciĂłn de esta Ăşltima especie como Squalus megalops (Macleay, 1881). Squalus megalops se encuentra en aguas australianas templadas y tropicales, y se piensa que habita tambiĂ©n en el Atlántico este, en el ocĂ©ano ĂŤndico sur y en el PacĂfico noroccidental, aunque estos registros deben ser confirmados. Nuestro estudio confirma su presencia en el mar Mediterráneo. La descripciĂłn tanto de S. blainvillei como de S. megalops está basada en especĂmenes capturados en aguas tunecinas
Methods for identifying surgical wound infection after discharge from hospital: a systematic review.
Background: Wound infections are a common complication of surgery that add significantly to the morbidity of patients and costs of treatment. The global trend towards reducing length of hospital stay post-surgery and the increase in day case surgery means that surgical site infections (SSI) will increasingly occur after hospital discharge. Surveillance of SSIs is important because rates of SSI are viewed as a measure of hospital performance, however accurate detection of SSIs post-hospital discharge is not straightforward. Methods: We conducted a systematic review of methods of post discharge surveillance for surgical wound infection and undertook a national audit of methods of post-discharge surveillance for surgical site infection currently used within United Kingdom NHS Trusts. Results: Seven reports of six comparative studies which examined the validity of post-discharge surveillance methods were located; these involved different comparisons and some had methodological limitations, making it difficult to identify an optimal method. Several studies evaluated automated screening of electronic records and found this to be a useful strategy for the identification of SSIs that occurred post discharge. The audit identified a wide range of relevant post-discharge surveillance programmes in England, Scotland and Wales and Northern Ireland; however, these programmes used varying approaches for which there is little supporting evidence of validity and/or reliability. Conclusion: In order to establish robust methods of surveillance for those surgical site infections that occur post discharge, there is a need to develop a method of case ascertainment that is valid and reliable post discharge. Existing research has not identified a valid and reliable method. A standardised definition of wound infection ( e. g. that of the Centres for Disease Control) should be used as a basis for developing a feasible, valid and reliable approach to defining post discharge SSI. At a local level, the method used to ascertain post discharge SSI will depend upon the purpose of the surveillance, the nature of available routine data and the resources available
COVID-19 vaccination in patients with immune thrombocytopenia
Immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by low platelet count and increased bleeding risk. COVID-19 vaccination has been described as risk factor for de novo ITP, but the effects of COVID-19 vaccination in patients with ITP are unknown. Our aims were to investigate the effects of COVID-19 vaccination in ITP patients on platelet count, bleeding complications and ITP exacerbation (any of: ≥50% decline in platelet count; or nadir platelet count 20% decrease from baseline; or use of rescue therapy). Platelet counts of ITP patients and healthy controls were collected immediately before, 1 and 4 weeks after first and second vaccination. Linear mixed-effects modelling was applied to analyze platelet counts over time. We included 218 ITP patients (50.9% female, mean age 55 years and median platelet count of 106x109/L) and 200 healthy controls (60.0% female, mean age 58 years and median platelet count of 256x109/L). Platelet counts decreased by 6.3% after vaccination. We observed no difference in decrease between the groups. Thirty ITP patients (13.8%, 95%CI 9.5%-19.1%) had an exacerbation and 5 (2.2%, 95%CI 0.7%-5.3%) suffered from a bleeding event. Risk factors for ITP exacerbation were platelet count <50x109/L (OR 5.3, 95%CI 2.1-13.7), ITP treatment at time of vaccination (OR 3.4, 95%CI 1.5-8.0) and age (OR 0.96 per year, 95%CI 0.94-0.99). Our study highlights safety of COVID-19 vaccination in ITP patients and importance of close monitoring platelet counts in a subgroup of ITP patients. ITP patients with exacerbation responded well on therapy
Indicators for the on-farm assessment of crop cultivar and livestock breed diversity: a survey-based participatory approach
International audienceAgrobiodiversity plays a fundamental role in guaranteeing food security. However, still little is known about the diversity within crop and livestock species: the genetic diversity. In this paper we present a set of indicators of crop accession and breed diversity for different farm types at farm-level, which may potentially supply a useful tool to assess and monitor farming system agrobiodiversity in a feasible and relatively affordable way. A generic questionnaire was developed to capture the information on crops and livestock in 12 European case study regions and in Uganda by 203 on-farm interviews. Through a participatory approach, which involved a number of stakeholders, eight potential indicators were selected and tested. Five of them are recommended as potentially useful indicators for agrobiodiversity monitoring per farm: (1) crop-species richness (up to 16 crop species), (2) crop-cultivar diversity (up to 15 crop cultivars, 1-2 on average), (3) type of crop accessions (landraces accounted for 3 % of all crop cultivars in Europe, 31 % in Uganda), (4) livestock-species diversity (up to 5 livestock species), and (5) breed diversity (up to five cattle and eight sheep breeds, on average 1-2).We demonstrated that the selected indicators are able to detect differences between farms, regions and dominant farm types. Given the present rate of agrobiodiversity loss and the dramatic effects that this may have on food production and food security, extensive monitoring is urgent. A consistent survey of crop cultivars and livestock breeds on-farm will detect losses and help to improve strategies for the management and conservation of on-farm genetic resources
Indikatoren zur Erfassung genetischer Vielfalt in biologischen und nicht-biologischen Landwirtschaftssystemen
Genetic variability is the fundament of life. Large genetic variability within species is the basis for adaptation to changing environmental conditions. Farmers and breeders have developed a multitude of crop cultivars and animal breeds to stabilize and increase quality and productivity. This study evaluated genetic diversity within different organic and non-organic farming systems using crop-cultivar and livestock-breed information as simple indicators. Data was collected using on-farm surveys in 15 case study regions in Europe and beyond. Selected indicators revealed strong differences of cultivar diversity between different countries and farming systems across Europe. No or only small differences were detectable between organic and non-organic farming systems. Landraces, as on-farm genetic resources, were under-represented in European case study regions
BIOBIO – Indikatoren für Biodiversität in ökologischen und ex-tensiven Anbausystemen
Organic and low-input farming systems provide habitats for wildlife on farmland. The EU FP7 project BIOBIO has identified a core set of 23 indicators relating to the diversity of habitats, of species, of crops and of livestock. Management indicators capturing the pressure on biodiversity are also proposed.
The indicators were identified in an iterative process between scientists and stake-holders to make sure that they are not only scientifically sound but also practicable and attractive. They were tested in 12 case study regions on four major farm types. Allocating 0.25 % of the CAP budget to a farm scale biodiversity monitoring would allow to measure and analyse the indicators on 50,000 farms across Europe
Alcoholic cirrhosis in Denmark – population-based incidence, prevalence, and hospitalization rates between 1988 and 2005: A descriptive cohort study
<p>Abstract</p> <p>Background</p> <p>Denmark has one of the highest alcohol consumption rates in Northern Europe. The overall per capita alcohol consumption has been stable in recent decades, but surveys have indicated that consumption has decreased in the young and increased in the old. However, there is no recent information on the epidemiology of alcoholic cirrhosis. We examined time trends in incidence, prevalence, and hospitalization rates of alcoholic cirrhosis in Denmark between 1988 and 2005.</p> <p>Methods</p> <p>We used data from a nationwide population-based hospital registry to identify all Danish citizens with a hospital diagnosis of alcoholic cirrhosis. We computed standardized incidence rates, prevalence and hospitalization rates of alcoholic cirrhosis within the Danish population. We also computed the number of hospitalizations per alcoholic cirrhosis patient per year.</p> <p>Results</p> <p>From 1988 to 1993, incidence rates for men and women of any age showed no clear trend, and after a 32 percent increase in 1994, rates were stable throughout 2005. In 2001–2005, the incidence rates were 265 and 118 per 1,000,000 per year for men and women, respectively, and the prevalence rates were 1,326 and 701 per 1,000,000. From 1994, incidence, prevalence, and hospitalization rates decreased for men and women younger than 45 years and increased in the older population, although the latter finding might be partly explained by changes in coding practice. Men and women born around 1960 or later had progressively lower age-specific alcoholic cirrhosis incidence rates than the generations before them. From 1996 to 2005, the number of hospitalizations per alcoholic cirrhosis patient per year increased from 1.3 to 1.5 for men and from 1.1 to 1.2 for women.</p> <p>Conclusion</p> <p>From 1988 to 2005, alcoholic cirrhosis put an increasing burden on the Danish healthcare system. However, the decreasing incidence rate in the population younger than 45 years from 1994 indicated that men and women born around 1960 or later had progressively lower incidence rates than the generations before them. Therefore, we expect the overall incidence and prevalence rates of alcoholic cirrhosis to decrease in the future.</p
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