84 research outputs found
Anderson, Benedict: Imagined Communities: Reflections on the Origin and Spread of Nationalism
Union Catalogs in a Changing Library World: An Introduction
The Andrew W. Mellon Foundation and the National Library of Estonia organized a Conference on Union Catalogs which took place in Tallinn, in the National Library of Estonia on October 17–19, 2002. The Conference presented and discussed analytical papers dealing with various aspects of designing and implementing union catalogs and shared cataloging systems as revealed through the experiences of Eastern European, Baltic and South African research libraries. Here you can find the texts of the conference papers and the list of contributors and participants.The Andrew W. Mellon Foundation and the National Library of Estonia organized a Conference on Union Catalogs which took place in Tallinn, in the National Library of Estonia on October 17–19, 2002. The Conference presented and discussed analytical papers dealing with various aspects of designing and implementing union catalogs and shared cataloging systems as revealed through the experiences of Eastern European, Baltic and South African research libraries. Here you can find the texts of the conference papers and the list of contributors and participants
Use of lung and brain perfusion imaging in the HELLP syndrome
Patients with multi-organ disorders may present with a plethora of confusing symptoms and signs. Often early diagnosis of significant disease is essential and can be difficult with standard radiological techniques. This case report presents the use of two radioisotopic techniques to assess brain and lung perfusion in a patient with such an acute-multi-organ disorder-the HELLP syndrome
Provocations of European Ethnology
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66376/1/aa.1997.99.4.713.pd
Contributors
The Andrew W. Mellon Foundation and the National Library of Estonia organized a Conference on Union Catalogs which took place in Tallinn, in the National Library of Estonia on October 17–19, 2002. The Conference presented and discussed analytical papers dealing with various aspects of designing and implementing union catalogs and shared cataloging systems as revealed through the experiences of Eastern European, Baltic and South African research libraries. Here you can find the texts of the conference papers and the list of contributors and participants.The Andrew W. Mellon Foundation and the National Library of Estonia organized a Conference on Union Catalogs which took place in Tallinn, in the National Library of Estonia on October 17–19, 2002. The Conference presented and discussed analytical papers dealing with various aspects of designing and implementing union catalogs and shared cataloging systems as revealed through the experiences of Eastern European, Baltic and South African research libraries. Here you can find the texts of the conference papers and the list of contributors and participants
Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations
Objective The Growth Hormone (GH) Research Society (GRS) convened a workshop to address important issues regarding trial design, efficacy, and safety of long-acting growth hormone preparations (LAGH).
Participants A closed meeting of 55 international scientists with expertise in GH, including pediatric and adult endocrinologists, basic scientists, regulatory scientists, and participants from the pharmaceutical industry.
Evidence Current literature was reviewed for gaps in knowledge. Expert opinion was used to suggest studies required to address potential safety and efficacy issues.
Consensus process Following plenary presentations summarizing the literature, breakout groups discussed questions framed by the planning committee. Attendees reconvened after each breakout session to share group reports. A writing team compiled the breakout session reports into a draft document that was discussed and revised in an open forum on the concluding day. This was edited further and then circulated to attendees from academic institutions for review after the meeting. Participants from pharmaceutical companies did not participate in the planning, writing, or in the discussions and text revision on the final day of the workshop. Scientists from industry and regulatory agencies reviewed the manuscript to identify any factual errors.
Conclusions LAGH compounds may represent an advance over daily GH injections because of increased convenience and differing phamacodynamic properties, providing the potential for improved adherence and outcomes. Better methods to assess adherence must be developed and validated. Long-term surveillance registries that include assessment of efficacy, cost-benefit, disease burden, quality of life, and safety are essential for understanding the impact of sustained exposure to LAGH preparations
Remote detection of invasive alien species
The spread of invasive alien species (IAS) is recognized as the most severe threat to biodiversity outside of climate change and anthropogenic habitat destruction. IAS negatively impact ecosystems, local economies, and residents. They are especially problematic because once established, they give rise to positive feedbacks, increasing the likelihood of further invasions and spread. The integration of remote sensing (RS) to the study of invasion, in addition to contributing to our understanding of invasion processes and impacts to biodiversity, has enabled managers to monitor invasions and predict the spread of IAS, thus supporting biodiversity conservation and management action. This chapter focuses on RS capabilities to detect and monitor invasive plant species across terrestrial, riparian, aquatic, and human-modified ecosystems. All of these environments have unique species assemblages and their own optimal methodology for effective detection and mapping, which we discuss in detail
Endocrine regulation of predator-induced phenotypic plasticity
Elucidating the developmental and genetic control of phenotypic plasticity remains a central agenda in evolutionary ecology. Here, we investigate the physiological regulation of phenotypic plasticity induced by another organism, specifically predator-induced phenotypic plasticity in the model ecological and evolutionary organism Daphnia pulex. Our research centres on using molecular tools to test among alternative mechanisms of developmental control tied to hormone titres, receptors and their timing in the life cycle. First, we synthesize detail about predator-induced defenses and the physiological regulation of arthropod somatic growth and morphology, leading to a clear prediction that morphological defences are regulated by juvenile hormone and life-history plasticity by ecdysone and juvenile hormone. We then show how a small network of genes can differentiate phenotype expression between the two primary developmental control pathways in arthropods: juvenoid and ecdysteroid hormone signalling. Then, by applying an experimental gradient of predation risk, we show dose-dependent gene expression linking predator-induced plasticity to the juvenoid hormone pathway. Our data support three conclusions: (1) the juvenoid signalling pathway regulates predator-induced phenotypic plasticity; (2) the hormone titre (ligand), rather than receptor, regulates predator-induced developmental plasticity; (3) evolution has favoured the harnessing of a major, highly conserved endocrine pathway in arthropod development to regulate the response to cues about changing environments (risk) from another organism (predator)
- …