Tratamiento de fracturas diafisarias inestables de fémur con clavo intramedular encerrojado tipo FMRP

Un grupo de 26 fracturas conminutas de fémur, rotacionalmente inestables, fueron tratadas con clavo intramedular encerrojado tipo FMRP. En 22 casos la conminución afectaba a más del 50% de la cortical. Del total de enclavados, 22 fueron estáticos y 4 dinámicos. La consolidación desde el punto de vista clínico y radiológico ocurrió en el 92% de los casos. En 2 casos se desarrolló un pseudoartrosis. Sólo un paciente mostró un acortamiento mayor de 1 cm. Una angulación mayor de 10° en cualquiera de los planos del espacio fue apreciada en 5 pacientes. No se produjo en ningún caso deformidad rotacional. El clavo intramedular encerrojado ha aumentado las indicaciones del enclavado intramedular en el tratamiento de las fracturas inestables de fémur. La incidencia de infección y pseudoartrosis es baja. La estabilidad del montaje permite una movilización inmediata del paciente, rehabilitación temprana y menor estancia intrahospitalaria. El clavo FMRP disminuye el tiempo de fluoroscopia, un fresado con instrumentos flexibles y es más barato que otros sistemas similares.Twenty six comminuted and rotationally unstable fractures of the femur were treated with the FMBP intramedullary locked nail. Twenty two of the fractures had comminution involving more than 50% of the cortex. Of the nailings, 22 were static and 4 dynamic. Clinical and radiographic union occurred in 92% of cases. There were 2 nonunions. There was one case of deep wound infection. Only one patient had a shortening greater than 1 cm. Angulation in any plane greater than 10° was noted in 5 patients. There were no instances of rotatory deformities. The interlocking nail has expanded the indications for the use of closed intramedullary nailing in the treatment of unstable femoral fractures. The incidence of infection and nonunion is low. Stability of the fractures allows immediate mobilization of the patients, early rehabilitation of the limb and shorter hospital stay. The FMRP nail eliminated fluoroscopy, flexible reamers and is cheaper as compared to other systems

Limits of Gaudin algebras, quantization of bending flows, Jucys--Murphy elements and Gelfand--Tsetlin bases

Gaudin algebras form a family of maximal commutative subalgebras in the tensor product of $n$ copies of the universal enveloping algebra U(\g) of a semisimple Lie algebra \g. This family is parameterized by collections of pairwise distinct complex numbers $z_1,...,z_n$. We obtain some new commutative subalgebras in U(\g)^{\otimes n} as limit cases of Gaudin subalgebras. These commutative subalgebras turn to be related to the hamiltonians of bending flows and to the Gelfand--Tsetlin bases. We use this to prove the simplicity of spectrum in the Gaudin model for some new cases.Comment: 11 pages, references adde

IDENTIFICACIÓN DE LA INTERACCIÓN DE MONOCITOS HUMANOS CON LAS LECTINAS DE Olneya tesota (IF2) Y Phaseolus vulgaris (PHA-L) POR CITOMETRÍA DE FLUJO

En este estudio se purificaron tres isolectinas (IF1, IF2 e IF3) de la lectina de palo fierro (PF2) a partir de las semillas de Olneya tesota, usando cromatografía de afinidad, seguida de intercambio iónico. La isoforma más abundante de PF2 (IF2) y la lectina de frijol PHA-L se utilizaron para identificar el patrón de reconocimiento hacia células mononucleares de sangre periférica humana por citometría de flujo. Todos los tipos sanguíneos (ABO) presentaron un perfil de reconocimiento similar por las lectinas. En particular, las estructuras oligosacáridas de los monocitos circulantes fueron reconocidas por IF2 y PHA-L con mayor intensidad que el resto de las células. Los linfocitos B y T presentaron una menor interacción con IF2 que con PHA-L. Los receptores carbohidrato de IF2 pudieran ser usados como marcadores potenciales de monocitos en patologías asociadas con estas células

Evaluación del efecto antioxidante y quimioprotector de extractos fenólicos de semillas de manzana

oai:grasasyaceites.revistas.csic.es:article/1Phenolic extracts from apple seeds (Malus domestica) belonging to the Red delicious (Rd) and Blanca de asturias (Ba) varieties were studied. Two extraction sequences with organic solvents were performed to evaluate hydrophilic phytochemicals: one with hexane, ethyl acetate and 50% methanol and the other with hexane and 70% acetone. For both apple varieties, acetone extracts showed higher total phenolics and condensed tannin content than ethyl acetate or aqueous methanol extracts. The same trend was observed with acetone extracts, which showed the highest free radical scavenging activity (%RSA). Bidimensional thin later chromatography plates gave positive evidence for proanthocyanidins (condensed tannins). The effect of crude  extracts on transformed cells (HeLa) was evaluated and found to be as strong as the positive control (catechin). Aqueous acetone extracts showed the highest inhibition to cell proliferation of all tested extracts and controls.Se estudiaron extractos fenólicos de semillas de manzana (Malus domestica) de variedades Red delicious (Rd) y Blanca de asturias (Ba). Se realizaron dos procedimientos de extracción sucesiva con solventes orgánicos para la evaluación de fitoquímicos con naturaleza hidrofílica, uno con hexano, acetato de etilo, metanol 50% y otro con hexano y acetona 70%. Los extractos acetónicos mostraron un mayor contenido de fenoles totales y de taninos condensados en comparación con los extractos de acetato de etilo y metanol acuoso en las dos variedades estudiadas. Independientemente de la variedad, los extractos acetónicos mostraron mayor capacidad atrapadora de radicales libre (%ARL), en comparación con los demás extractos. El análisis cromatográfico de los extractos mediante capa fina bidimensional fue positivo para proantocianidinas (taninos condensados). También se evaluó el efecto biológico de los extractos crudos sobre la proliferación de células transformadas (células HeLa), mismo que fue equivalente al control positivo de catequina. Los extractos acetónicos mostraron el mayor efecto inhibitorio en la proliferación celular entre todos los extractos y controles

Meromorphic tensor equivalence for Yangians and quantum loop algebras

Let ${\mathfrak g}$ be a complex semisimple Lie algebra, and $Y_h({\mathfrak g})$, $U_q(L{\mathfrak g})$ the corresponding Yangian and quantum loop algebra, with deformation parameters related by $q=\exp(\pi i h)$. When $h$ is not a rational number, we constructed in arXiv:1310.7318 a faithful functor $\Gamma$ from the category of finite-dimensional representations of $Y_h ({\mathfrak g})$ to those of $U_q(L{\mathfrak g})$. The functor $\Gamma$ is governed by the additive difference equations defined by the commuting fields of the Yangian, and restricts to an equivalence on a subcategory of $Y_h({\mathfrak g})$ defined by choosing a branch of the logarithm. In this paper, we construct a tensor structure on $\Gamma$ and show that, if $|q|\neq 1$, it yields an equivalence of meromorphic braided tensor categories, when $Y_h({\mathfrak g})$ and $U_q(L{\mathfrak g})$ are endowed with the deformed Drinfeld coproducts and the commutative part of the universal $R$-matrix. This proves in particular the Kohno-Drinfeld theorem for the abelian $q$KZ equations defined by $Y_h({\mathfrak g})$. The tensor structure arises from the abelian $q$KZ equations defined by a appropriate regularisation of the commutative $R$-matrix of $Y_h({\mathfrak g})$.Comment: Title changed, details added. 67 pages, 1 figure. Final version, to appear in Publ. Math IHE

A 2-categorical extension of Etingof–Kazhdan quantisation

Let k be a field of characteristic zero. Etingof and Kazhdan constructed a quantisation U_h(b) of any Lie bialgebra b over k, which depends on the choice of an associator Phi. They prove moreover that this quantisation is functorial in b. Remarkably, the quantum group U_h(b) is endowed with a Tannakian equivalence F_b from the braided tensor category of Drinfeld-Yetter modules over b, with deformed associativity constraints given by Phi, to that of Drinfeld-Yetter modules over U_h(b). In this paper, we prove that the equivalence F_b is functorial in b.Comment: Small revisions in Sections 2 and 6. An appendix added on the equivalence between admissible Drinfeld-Yetter modules over a QUE and modules over its quantum double. To appear in Selecta Math. 71 page

Asymptotic equivalence of discretely observed diffusion processes and their Euler scheme: small variance case

This paper establishes the global asymptotic equivalence, in the sense of the Le Cam $\Delta$-distance, between scalar diffusion models with unknown drift function and small variance on the one side, and nonparametric autoregressive models on the other side. The time horizon $T$ is kept fixed and both the cases of discrete and continuous observation of the path are treated. We allow non constant diffusion coefficient, bounded but possibly tending to zero. The asymptotic equivalences are established by constructing explicit equivalence mappings.Comment: 21 page

Electrocardiographic findings in patients with arrhythmogenic cardiomyopathy and right bundle branch block ventricular tachycardia.

AIMS: Little is known about patients with right bundle branch block (RBBB)-ventricular tachycardia (VT) and arrhythmogenic cardiomyopathy (ACM). Our aims were: (i) to describe electrocardiogram (ECG) characteristics of sinus rhythm (SR) and VT; (ii) to correlate SR with RBBB-VT ECGs; and (iii) to compare VT ECGs with electro-anatomic mapping (EAM) data. METHODS AND RESULTS: From the European Survey on ACM, 70 patients with spontaneous RBBB-VT were included. Putative left ventricular (LV) sites of origin (SOOs) were estimated with a VT-axis-derived methodology and confirmed by EAM data when available. Overall, 49 (70%) patients met definite Task Force Criteria. Low QRS voltage predominated in lateral leads (n = 37, 55%), but QRS fragmentation was more frequent in inferior leads (n = 15, 23%). T-wave inversion (TWI) was equally frequent in inferior (n = 28, 42%) and lateral (n = 27, 40%) leads. TWI in inferior leads was associated with reduced LV ejection fraction (LVEF; 46 ± 10 vs. 53 ± 8, P = 0.02). Regarding SOOs, the inferior wall harboured 31 (46%) SOOs, followed by the lateral wall (n = 17, 25%), the anterior wall (n = 15, 22%), and the septum (n = 4, 6%). EAM data were available for 16 patients and showed good concordance with the putative SOOs. In all patients with superior-axis RBBB-VT who underwent endo-epicardial VT activation mapping, VT originated from the LV. CONCLUSIONS: In patients with ACM and RBBB-VT, RBBB-VTs originated mainly from the inferior and lateral LV walls. SR depolarization and repolarization abnormalities were frequent and associated with underlying variants