15 research outputs found
A propos de la collaboration entre les professionnels des bibliothèques et les universitaires
Processing of spatial-frequency altered faces in schizophrenia: Effects of illness phase and duration
Low spatial frequency (SF) processing has been shown to be impaired in people with schizophrenia, but it is not clear how this varies with clinical state or illness chronicity. We compared schizophrenia patients (SCZ, n534), first episode psychosis patients (FEP, n522), and healthy controls (CON, n535) on a gender/facial discrimination task. Images were either unaltered (broadband spatial frequency, BSF), or had high or low SF information removed (LSF and HSF conditions, respectively). The task was performed at hospital admission and discharge for patients, and at corresponding time points for controls. Groups were matched on visual acuity. At admission, compared to their BSF performance, each group was significantly worse with low SF stimuli, and most impaired with high SF stimuli. The level of impairment at each SF did not depend on group. At discharge, the SCZ group performed more poorly in the LSF condition than the other groups, and showed the greatest degree of performance decline collapsed over HSF and LSF conditions, although the latter finding was not significant when controlling for visual acuity. Performance did not change significantly over time for any group. HSF processing was strongly related to visual acuity at both time points for all groups. We conclude the following: 1) SF processing abilities in schizophrenia are relatively stable across clinical state; 2) face processing abnormalities in SCZ are not secondary to problems processing specific SFs, but are due to other known difficulties constructing visual representations from degraded information; and 3) the relationship between HSF processing and visual acuity, along with known SCZ- and medication-related acuity reductions, and the elimination of a SCZ-related impairment after controlling for visual acuity in this study, all raise the possibility that some prior findings of impaired perception in SCZ may be secondary to acuity reductions
Differential item functioning (DIF) of SF-12 and Q-LES-Q-SF items among french substance users
A propos de la collaboration entre les professionnels des bibliothèques et les universitaires
Atmospheric pressure photoionization using tunable VUV synchrotron radiation
Document Type : Proceedings Paper Conference Date : JUN 21-25, 2011 Conference Location : Belgrade, SERBIA Conference Sponsor : Univ Belgrade, Inst Phys, Serbian Acad Sci & Arts (SASA), Republ Serbia, Minist Educ & Sci, Serbian Phys Soc, Serv Cooperat dact culturelle Ambassade France Serbie, Osterreichisches Kulturforum BelgradWe report here the first coupling of an atmospheric pressure photoionization (APPI) source with a synchrotron radiation beamline in the vacuum ultra-violet (VUV). A commercial APPI source of a QStar Pulsar i from Sciex was modified to receive photons from the DISCO beamline at the SOLEIL synchrotron radiation facility. Photons are delivered at atmospheric pressure in the 4-20 eV range. The advantages of this new set up, termed SR-APPI, over classical APPI are spectral purity and continuous tunability. The technique may also be used to perform tunable photoionization mass spectrometry on fragile compounds difficult to vaporize by classical methods. (C) 2011 Elsevier B.V. All rights reserved
cis-Annonacin and (2,4)-cis-andtrans-isoannonacins: Cytotoxic monotetrahydrofuran annonaceous acetogenins from the seeds ofAnnona cherimolia
Red blood cell aggregability in patients with a history of leg vein thrombosis: influence of post-thrombotic treatment
NORMALISATION, ACADEMISATION, UNIVERSITARISATION, PARTENARIAT: DE LA DIVERSITÉ DES VOIES VERS L'UNIVERSITÉ
Metadoxine in the Treatment of Acute and Chronic Alcoholism: A Review
Alcohol abuse and alcoholism are responsible for a wide variety of medical problems. The pharmacotherapeutic aspect of alcoholism includes the use of drugs, with different actions and objectives. Among them, metadoxine seems to be of interest. Metadoxine is able to accelerate the elimination of alcohol from the blood and tissues, to help restore the functional structure of the liver and to relieve neuro-psychological disorders associated with alcohol intoxication. Metadoxine also seems to be safe; in more than 15 years of post-marketing surveillance only minor aspecific and reversible events were monitored in patients exposed to the treatment. In this review the preclinical and clinical results obtained using metadoxine in acute and chronic alcohol intoxication are reported