591 research outputs found

    Detailed analysis of an endoreversible fuel cell : Maximum power and optimal operating temperature determination

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    Producing useful electrical work in consuming chemical energy, the fuel cell have to reject heat to its surrounding. However, as it occurs for any other type of engine, this thermal energy cannot be exchanged in an isothermal way in finite time through finite areas. As it was already done for various types of systems, we study the fuel cell within the finite time thermodynamics framework and define an endoreversible fuel cell. Considering different types of heat transfer laws, we obtain an optimal value of the operating temperature, corresponding to a maximum produced power. This analysis is a first step of a thermodynamical approach of design of thermal management devices, taking into account performances of the whole system.Comment: 15 pages, 10 figure

    Infection control measures in ophthalmology during the COVID-19 outbreak: A narrative review from an early experience in Italy

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    Introduction: The novel coronavirus (SARS-CoV-2) is infecting people and spreading easily from person-to-person. Cases have been detected in most countries worldwide. Italy is one of the most affected countries as of 30 March 2020. Public health response includes a rapid reorganization of the Italian National Healthcare System in order to reduce transmission of COVID-19 within hospitals and healthcare facilities, while optimizing the assistance to patients with severe COVID-19 complications. Methods: We analysed the actions that were taken in three ophthalmology centres in northern Italy during the SARS-CoV-2 outbreak and how these measures affected patient\u2019s attendance. In addition, due to the rapidly evolving scenario, we reviewed the evidence available during the course of this pandemic. Results: A full reorganization of ophthalmology services is mandatory according to current existing infection containment measures in order to continue dispensing urgent procedures without endangering the community with amplification of the diffusion chain. Ophthalmologists are considered at elevated risk of exposure when caring patients and vice versa, due to their close proximity during eye examination. High volumes of procedures typically generated by ophthalmologists with concurrent implications on the risk of infection are considered when re-assessing healthcare facilities reorganization. Conclusion: Containment measures in the event of pandemic due to infective agents should be well known by healthcare professionals and promptly applied in order to mitigate the risk of nosocomial transmission and outbreak

    Lean maturity assessment in eto scenario

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    The obligatory path towards a lean manufacturing organization requires assessment and monitoring. However, a lean assessment framework is not yet available for the engineer to order (ETO) scenario. This work explored ten lean ETO maturity principles—identified from the literature—that take insight from three formally defined sets (Toyota Way, lean construction, and lean product development principles). A practical assessment model was proposed based on the evaluation of ten lean ETO objective criteria (four with mathematical formulation) and was validated on a real industrial case. A problem‐solving tool, including a new lean tool, called the Problem Focus Matrix (PFM), was also presented; this tool was aimed toward development of an integrated framework that would include the organization mission, management, and continuous improvement

    On the Design of Constructively Aligned Educational Unit

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    Modern pedagogy is moving away from traditional transmissive approaches, and it is extensively embracing constructive theory of learning. A prominent practical embodiment of this paradigm shift is a method called Constructive Alignment (CA). This approach focuses on learners’ actions and starts from a clear communication of the Intended Learning Outcomes (ILOs) of the focal unit. ILOs are made of content, a context, and an Educational Goal Verb (EGV). According to the Bloom Taxonomy, the EGV is the core of an ILO and refers to the action the learners are expected to be able to master after completing the educational unit. The ILO is then aligned to the course activity using the EGV (i.e., EGVs are enacted through Teaching and Learning Activities (TLAs) and verified through Assessment Tasks (ATs)). Despite the ILO definition being extensively investigated and described, the extant literature has poorly explored how to devise suitable TLAs and ATs, lacking comprehensive contributions that identify and describe the different kinds of TLAs and ATs available to course designers. In view of the above gap, the authors searched and reviewed the literature (scientific papers (i.e., top-down, deductive approach)) and practices in higher education (university websites and blogs (i.e., bottom-up, inductive approach)) to identify all the possible sources of TLA and AT descriptions available. The results propose standardized templates that support the course design process, providing extensive descriptions of TLA and AT based on the best practices identified. The proposed templates include the core dimensions that proved to be suitable for designing traditional and remote-learning activities. Finally, the examples provided in the paper show how to use these templates on a few kinds of selected on-campus and digital TLAs and ATs from the educational units identified in the Erasmus+ MAESTRO project, which is based on Industry 4.0 technological enablers and their application in support of manufacturing sustainability

    The Deuterium Abundance in the z=0.7 absorber towards QSO PG1718+4807

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    We report a further analysis of the ratio of deuterium to hydrogen (D/H) using HST spectra of the z=0.701 Lyman limit system towards the QSO PG1718+481. Initial analyses of this absorber found it gave a high D/H value, 1.8 - 3.1 \times 10^{-4} (Webb et al. 1998), inconsistent with several higher redshift measurements. It is thus important to critically examine this measurement. By analysing the velocity widths of the DI, HI and metal lines present in this system, Kirkman et al. (2001) report that the additional absorption in the blue wing of the lya line can not be DI, with a confidence level of 98%. Here we present a more detailed analysis, taking into account possible wavelength shifts between the three sets of HST spectra used in the analysis. We find that the constraints on this system are not as strong as those claimed by Kirkman et al. The discrepancy between the parameters of the blue wing absorption and the parameters expected for DI is marginally worse than 1 sigma. Tytler et al.(1999) commented on the first analysis of Webb et al.(1997,1998), reporting the presence of a contaminating lower redshift Lyman limit system, with log[N(HI)] = 16.7 at z=0.602, which biases the N(HI) estimate for the main system. Here we show that this absorber actually has log[N(HI)] < 14.6 and does not impact on the estimate of N(HI) in the system of interest at z = 0.701. The purpose of the present paper is to highlight important aspects of the analysis which were not explored in previous studies, and hence help refine the methods used in future analyses of D/H in quasar spectra.Comment: 11 pages, 9 figures. Accepted by MNRA

    Sustained impairment of human cytomegalovirus (HCMV)-specific CD4+ and CD8+ T cell response is responsible for recurrent episodes of disseminated HCMV infection in a D+R- hand transplant recipient

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    Human cytomegalovirus (HCMV) infection is the major viral complication in solid organ transplant recipients. Seronegative recipents (R-) of organs from seropositive donors (D+) appear to be at higher risk of developing symptomatic HCMV infection. To what extent systemic life-threatening complications can be risked for non-life-saving transplant procedures? A case report describing successful treatment of repeated episodes of active HCMV infection in a D+R- hand recipient in the absence of HCMV-specific T-cell immunity is presented. In the attempt to save both the patient and the transplanted hand, a preemptive treatment strategy was adopted with the aim to boost the constitution of the virus-specific T-cell immune response and simultaneously avoid onset of disease. Careful monitoring of HCMV load in blood and HCMV-specific T-cell immunity guided administration of repeated courses of antiviral treatment and avoided emergence of HCMV-related symptoms. Following establishment of HCMV-specific CD4+ and CD8+ T-cell response, preemptive treatment was no longer required due to sustained HCMV disappearance from blood. The patient is now well, and his hand too. In conclusion, evaluation of virus-specific T-cell immunity is of crucial importance in D+R- transplant recipients and careful monitoring of HCMV-specific T cell mediated response should always parallel monitoring of HCMV load in transplant recipients

    Scleral fixation of a single-piece foldable acrylic IOL through a 1.80 mm corneal incision

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    A new scleral fixation technique of a single-piece acrylic foldable intraocular lens (IOL) (enVista MX60, Bausch & Lomb, Inc.) through a 1.80 mm corneal incision, using the IOL eyelets as anchoring point, is described. It was a retrospective review of 26 cases. The preoperative mean corrected distance visual acuity was 0.51 \ub1 0.21 logarithm of the minimum angle of resolution (logMAR). It improved significantly to 0.25 \ub1 0.27 logMAR (P < .01), 0.18 \ub1 0.16 logMAR (P < .01), and 0.17 \ub1 0.16 logMAR (P < .01) (at 1 month, 3 months, and 6 months postoperatively, respectively, repeated measures analysis of variance, P < .0001). No astigmatism increase of more than 0.75 diopters was recorded at any time point. In all 26 patients, the IOL was well centered and stable for the entire monitoring period. No complications were observed during follow-up. Scleral fixation of the foldable IOL through a 1.80 mm corneal incision provided excellent IOL stability during the 6-month follow-up of this study and might be an effective and safe surgical technique

    An instrument for the characterization and calibration of optical sensors

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    This paper presents the development of a hardware/software system for the characterization of the electronic response of optical (camera) sensors such as matrix and linear color and monochrome Charge Coupled Device (CCD) or Complementary Metal Oxide Semiconductor (CMOS). The electronic response of a sensor is required for inspection purposes. It also allows the design and calibration of the integrating device to achieve the desired performance. The proposed instrument equipment fulfills the most recent European Machine Vision Association (EMVA) 1288 standard ver. 3.1: The spatial non uniformity of the illumination ΔE must be under 3%, and the sensor must achieve an f-number of 8.0 concerning the light source. The following main innovations have achieved this: An Ulbricht sphere providing a uniform light distribution (irradiation) of 99.54%; an innovative illuminator with proper positioning of color Light Emitting Diodes (LEDs) and control electronics; and a flexible C# program to analyze the sensor parameters, namely Quantum Efficiency, Overall System Gain, Temporal Dark Noise, Dark Signal Non Uniformity (DSNU1288), Photo Response Non-Uniformity (PRNU1288), Maximum achievable Signal to Noise Ratio (SNRmax), Absolute sensitivity threshold, Saturation Capacity, Dynamic Range, and Dark Current. This new instrument has allowed a camera manufacturer to design, integrate, and inspect numerous devices and camera models (Necta, Celera, and Aria)
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