CURRENT ISSUES AFFECTING TRADE AND TRADE POLICY: AN ANNOTATED LITERATURE REVIEW

This review provides a base of literature describing current issues and research on the impacts of lobalization and the industrialization of agriculture and recent approaches to analyze and model agricultural trade and trade policies. Three key factors of the survey are differentiated goods, global economic integration and international supply chain linkages. The review covers 182 publications, which are presented alphabetically by author with a brief annotation describing how it relates to the above criteria. The articles are also indexed by keyword. A brief summary highlights the documented literature and includes a series of issues for future discussion and research.International Relations/Trade,

FinTech platform regulation: Regulating with/against platforms in the United Kingdom and China

This paper develops case studies of the United Kingdom (UK) and China to analyse divergent national financial regulatory approaches to FinTech as a novel political economy of platforms. Regulating with platforms is core to the approach taken in the UK, where start-up and early-career platforms are enrolled into an innovation-friendly financial regulation regime that promotes consumption and competition balanced with stability. In China, meanwhile, measures are being instituted to enhance rules and restrictions imposed on FinTech platforms. BigTech-led FinTech expansion was encouraged to expedite financial reforms to fuel economic growth and ensure authoritarian state control, but regulation is now shown to be working against the furtherance of platform power

Capitalising on the crowd: the monetary and financial ecologies of crowdfunding

‘Crowdfunding’ is a method of raising money and finance to capitalise projects of various kinds. Drawing on the networking capabilities of the internet and software platforms, those seeking project funding appeal to potentially diverse audiences who are collectively referred to as ‘the crowd’. What practitioners, advocates and policymakers typically identify within crowdfunding is its ‘alternative’, ‘disruptive’ and ‘democratising’ qualities; that is, it is held to be a novel, digitally-rendered economic space which has the capacity to challenge established funding practices in banking, capital markets and venture capital networks, offering a more open and egalitarian source of capital for economic, social and cultural entrepreneurship. The paper develops the concept of ‘ecologies’, drawn from the geographies of money and finance literature, to advance a critical understanding of the crowdfunding economy that is sceptical of its apparent qualities. First, the concept of ecologies encourages the analysis of diverse and proliferative monetary and financial forms, enabling an understanding that avoids the binary opposition of ‘capitalist/alternative’ economic forms and which differentiates between the variegated crowdfunding ecologies that have emerged to date. Second, by foregrounding the intermediation processes and credit-debt relations of monetary and financial ecologies, it is argued that crowdfunding may largely replicate rather than disrupt the extant institutional and debt dynamics of funding practices. Third, by emphasizing the socio-spatial effects of monetary and financial ecologies, attention is drawn to the need for further research into the unevenness that mitigates against crowdfunding being as open and egalitarian as its advocates claim

Platform capitalism: the intermediation and capitalization of digital economic circulation

A new form of digital economic circulation has emerged, wherein ideas, knowledge, labour and use rights for otherwise idle assets move between geographically distributed but connected and interactive online communities. Such circulation is apparent across a number of digital economic ecologies, including social media, online marketplaces, crowdsourcing, crowdfunding and other manifestations of the so-called ‘sharing economy’. Prevailing accounts deploy concepts such as ‘co-production’, ‘prosumption’ and ‘peer-to-peer’ to explain digital economic circulation as networked exchange relations characterised by their disintermediated, collaborative and democratizing qualities. Building from the neologism of platform capitalism, we place ‘the platform’ – understood as a distinct mode of socio-technical intermediary and business arrangement that is incorporated into wider processes of capitalization – at the centre of the critical analysis of digital economic circulation. To create multi-sided markets and coordinate network effects, platforms enrol users through a participatory economic culture and mobilize code and data analytics to compose immanent infrastructures. Platform intermediation is also nested in the ex-post construction of a replicable business model. Prioritizing rapid up-scaling and extracting revenues from circulations and associated data trails, the model performs the structure of venture capital investment which capitalizes on the potential of platforms to realize monopoly rents

Opportunistic detection of atrial fibrillation using blood pressure monitors: a systematic review

Background: Atrial Fibrillation (AF) affects around 2% of the population and early detection is beneficial, allowing patients to begin potentially life-saving anticoagulant therapies. Blood pressure (BP) monitors may offer an opportunity to screen for AF. Aim: To identify and appraise studies which report the diagnostic accuracy of automated BP monitors used for opportunistic AF detection. Methods: A systematic search was performed of the Medline, Medline-in-process and Embase literature databases. Papers were eligible if they described primary studies of the evaluation of a BP device for AF detection, were published in a peer reviewed journal and reported values for the sensitivity and specificity. Included studies were appraised using the QUADAS-2 tool to assess their risk of bias and applicability to opportunistic AF detection. Values for the sensitivity and specificity of AF detection were extracted from each paper and compared. Results and Conclusion: We identified seven papers evaluating six devices from two manufacturers. Only one study scored low risk in all of the QUADAS-2 domains. All studies reported specificity greater than 85% and six reported sensitivity greater than 90%. The studies showed that blood pressure devices with embedded algorithms for detecting arrhythmias show promise as screening tools for AF, comparing favourably with manual pulse palpation. But the studies used different methodologies and many were subject to potential bias. More studies are needed to more precisely define the sensitivity and specificity of opportunistic screening for AF during blood pressure measurement before its clinical utility in the population of interest can be assessed fully

Empathetic design research and development in practice; co-development of an innovative head and neck support for people with Motor Neurone Disease

People with Motor Neuron Disease (MND) experience muscle weakness. The human head can weigh 5kg so when this happens in the muscles around the neck it can become very difficult to hold the head up and result in the head falling forward. The situation can lead to extreme pain, restricted movement, problems with eating, drinking, swallowing, breathing and importantly adversely affect face to face communication. Ideally, a neck collar would help alleviate these important quality of life (QoL) issues. Current neck collar provision can be of limited use for people with MND and are regularly rejected by users as often they are designed to immobilise the head and neck, and can be socially stigmatising. A fundamental reappraisal of the way these physical products are configured and used was undertaken. The project explored the use of open and empathic approaches to the co-design of solutions and further product designs role as developer and explorer of complex multidisciplinary, social and QoL issues. It demonstrates experts working openly together using a range of 'live' research practice methods to arrive at holistically considered optimum outcomes. The project was funded by the NIHR i4i program. The team consisted of clinicians, engineers and designers working with partners including people experiencing MND and their carers. Processes included a range of research through design methods at the heart of which was a series of ten, iterative, co-design workshops. The team developed mutual empathies between project participants. These played a key role in the motivation to reach appropriate solutions

Accuracy of pulse interval timing in ambulatory blood pressure measurement

Blood pressure (BP) monitors rely on pulse detection. Some blood pressure monitors use pulse timings to analyse pulse interval variability for arrhythmia screening, but this assumes that the pulse interval timings detected from BP cuffs are accurate compared with RR intervals derived from ECG. In this study we compared the accuracy of pulse intervals detected using an ambulatory blood pressure monitor (ABPM) with single lead ECG. Twenty participants wore an ABPM for three hours and a data logger which synchronously measured cuff pressure and ECG. RR intervals were compared with corresponding intervals derived from the cuff pressure tracings using three different pulse landmarks. Linear mixed effects models were used to assess differences between ECG and cuff pressure timings and to investigate the effect of potential covariates. In addition, the maximum number of successive oscillometric beats detectable in a measurement was assessed. From 243 BP measurements, the foot landmark of the oscillometric pulse was found to be associated with fewest covariates and had a random error of 9.5 ms. 99% of the cuff pressure recordings had more than 10 successive detectable oscillometric beats. RR intervals can be accurately estimated using an ABPM

OER: A Field Guide for Academic Librarians

We intend this book to act as a guide writ large for would-be champions of OER, that anyone—called to action by the example set by our chapter authors—might serve as guides themselves. The following chapters tap into the deep experience of practitioners who represent a meaningful cross section of higher education institutions in North America. It is our hope that the examples and discussions presented by our authors will facilitate connections among practitioners, foster the development of best practices for OER adoption and creation, and more importantly, lay a foundation for novel, educational excellence.https://scholarworks.boisestate.edu/fac_books/1510/thumbnail.jp

Morphologically-directed Raman Spectroscopy for Forensic Soil Analysis

Morphologically-directed Raman spectroscopy (MDRS) is a novel yet reliable analytical technique that can be used for a variety of forensic applications, enabling scientists to gain more information from samples than they obtain using more traditional methods. In soil forensics, MDRS delivers particle size distribution and microscopic morphological characteristics for the particles present, and at the same time allows secure mineral identification. In this article, we explore the benefits of utilizing soil in forensic investigations, and demonstrate the value of applying MDRS. Two case studies illustrate the real-life potential and applications of this technology

Economic evaluation of short treatment for multidrugresistant tuberculosis, Ethiopia and South Africa : the STREAM trial

OBJECTIVE STREAM was a phase-III non-inferiority randomised controlled trial (RCT) to evaluate a shortened regimen for multi-drug resistant tuberculosis (MDR-TB), and included the first-ever within-trial economic evaluation of such regimens, reported here. METHODS We compared the costs of ‘Long’ (20-22 months) and ‘Short’ (9-11 months) regimens in Ethiopia and South Africa. Cost data were collected from trial participants, and health system costs estimated using ‘bottom-up’ and ‘top-down’ costing approaches. A cost-effectiveness analysis was conducted with the trial primary outcome as the measure of effectiveness, including a probabilistic sensitivity analysis (PSA) to illustrate decision uncertainty. FINDINGS The Short-regimen reduced healthcare costs per case by 21% in South Africa (US$8,341 Long vs US$6,619 Short) and 25% in Ethiopia (US$6,097 Long vs US$4,552 Short). The largest component of this saving was medication in South Africa (67%) and social support in Ethiopia (35%). In Ethiopia, participants on the Short-regimen reported reductions in dietary supplementation expenditure (US$225 per case (95$13 (95%CI 11-14), South Africa US$64 (95$19,000 (Ethiopia) or <US$14,500 (South Africa). CONCLUSION The Short-regimen provided substantial health system cost savings and reduced financial burden on participants. Shorter regimens are likely to be cost-effective in most settings, and an effective strategy to support the WHO goal of eliminating catastrophic costs in T