868 research outputs found
Investigation of Some Factors Relating to the Teaching of Clothing Construction to Teenage Indian Girls
Clothing, Textiles, and Merchandisin
History of the Domestic Violence Coordinating Committee: 1987-2000
This chapter describes the emergence of an entity dedicated to improving inter-agency
coordination in domestic violence service delivery, the Domestic Violence Coordinating
Committee (DVCC), then charts its work and activity level from its formation in 1987 to the
time this research was conducted in 2000. In addition to an overview of the history of the
DVCC, this chapter includes a discussion of the factors found pertinent for success and failure of
DVCC, and a concluding section where these themes are drawn into an analytical framework.
Special attention is given to the role of the police department and its relationships over time with
the DVCC and with the individual agencies in the domestic violence service community
Identification of Mammalian Mediator Subunits with Similarities to Yeast Mediator Subunits Srb5, Srb6, Med11, and Rox3
The Mediator is a multiprotein coactivator required for activation of RNA polymerase II transcription by DNA binding transactivators. We recently identified a mammalian homologue of yeast Mediator subunit Med8 and partially purified a Med8-containing Mediator complex from rat liver nuclei (Brower, C. S., Sato, S., Tomomori-Sato, C., Kamura, T., Pause, A., Stearman, R., Klausner, R. D., Malik, S., Lane, W. S., Sorokina, I., Roeder, R. G., Conaway, J. W., and Conaway, R. C. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 10353-10358). Analysis of proteins present in the most highly purified Med8-containing fractions by tandem mass spectrometry led to the identification of many known mammalian Mediator subunits, as well as four potential Mediator subunits exhibiting sequence similarity to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3. Here we present direct biochemical evidence that these four proteins are bona fide mammalian Mediator subunits. In addition, we identify direct pairwise binding partners of these proteins among the known mammalian Mediator subunits. Taken together, our findings identify a collection of novel mammalian Mediator subunits and shed new light on the underlying architecture of the mammalian Mediator complex
Comparing Bedside Methods of Determining Placement of Gastric Tubes in Children
Purpose
The purpose of this study was to compare the accuracy and predictive validity of pH, bilirubin, and CO2 in identifying gastric tube placement errors in children.
Design and Methods
After the tube was inserted into 276 children, the CO2 monitor reading was obtained. Fluid was then aspirated to test pH and bilirubin.
Results
Lack of ability to obtain tube aspirate was the best predictor of NG/OG placement errors with a sensitivity of 34.9% and a positive predictive value of 66.7%. Measuring pH, bilirubin, and CO2 of tube aspirate was less helpful.
Practice Implications
Health care providers should suspect NG/OG tube misplacement when no fluid is aspirated
Speaking out about gender imbalance in invited speakers improves diversity.
Omissions of qualified women scientists from major meeting programs continue to occur despite a surge in articles indicating persistent gender-discriminatory practices in hiring and promotion, and calls for gender balance in conference organizing committees
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