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Television advertising and children: lessons from policy development
Decoherence suppression via environment preparation
To protect a quantum system from decoherence due to interaction with its
environment, we investigate the existence of initial states of the environment
allowing for decoherence-free evolution of the system. For models in which a
two-state system interacts with a dynamical environment, we prove that such
states exist if and only if the interaction and self-evolution Hamiltonians
share an eigenstate. If decoherence by state preparation is not possible, we
show that initial states minimizing decoherence result from a delicate
compromise between the environment and interaction dynamics.Comment: 4 pages, 2 figure
Deviational simulation of phonon transport in graphene ribbons with ab initio scattering
We present a deviational Monte Carlo method for solving the Boltzmann-Peierls equation with ab initio 3-phonon scattering, for temporally and spatially dependent thermal transport problems in arbitrary geometries. Phonon dispersion relations and transition rates for graphene are obtained from density functional theory calculations. The ab initio scattering operator is simulated by an energy-conserving stochastic algorithm embedded within a deviational, low-variance Monte Carlo formulation. The deviational formulation ensures that simulations are computationally feasible for arbitrarily small temperature differences, while the stochastic treatment of the scattering operator is both efficient and exhibits no timestep error. The proposed method, in which geometry and phonon-boundary scattering are explicitly treated, is extensively validated by comparison to analytical results, previous numerical solutions and experiments. It is subsequently used to generate solutions for heat transport in graphene ribbons of various geometries and evaluate the validity of some common approximations found in the literature. Our results show that modeling transport in long ribbons of finite width using the homogeneous Boltzmann equation and approximating phonon-boundary scattering using an additional homogeneous scattering rate introduces an error on the order of 10% at room temperature, with the maximum deviation reaching 30% in the middle of the transition regime.Singapore-MIT Alliance for Research and TechnologyAmerican Society for Engineering Education. National Defense Science and Engineering Graduate FellowshipNational Science Foundation (U.S.). Graduate Research Fellowshi
A configuration system for the ATLAS trigger
The ATLAS detector at CERN's Large Hadron Collider will be exposed to
proton-proton collisions from beams crossing at 40 MHz that have to be reduced
to the few 100 Hz allowed by the storage systems. A three-level trigger system
has been designed to achieve this goal. We describe the configuration system
under construction for the ATLAS trigger chain. It provides the trigger system
with all the parameters required for decision taking and to record its history.
The same system configures the event reconstruction, Monte Carlo simulation and
data analysis, and provides tools for accessing and manipulating the
configuration data in all contexts.Comment: 4 pages, 2 figures, contribution to the Conference on Computing in
High Energy and Nuclear Physics (CHEP06), 13.-17. Feb 2006, Mumbai, Indi
Incidence and severity of childhood pneumonia in the first year of life in a South African birth cohort: the Drakenstein Child Health Study
Background Childhood pneumonia causes substantial mortality and morbidity. Accurate measurements of pneumonia
incidence are scarce in low-income and middle-income countries, particularly after implementation of pneumococcal
conjugate vaccine. We aimed to assess the incidence, severity, and risk factors for pneumonia in the fi rst year of life
in children enrolled in a South African birth cohort.
Methods This birth cohort study is being done at two sites in Paarl, a periurban area of South Africa. We enrolled
pregnant women (>18 years) and followed up mother–infant pairs to 1 year of age. We obtained data for risk factors
and respiratory symptoms. Children received 13-valent pneumococcal conjugate vaccine according to national
immunisation schedules. We established pneumonia surveillance systems and documented episodes of ambulatory
pneumonia and pneumonia warranting hospital admission. We calculated incidence rate ratios for pneumonia with
mixed-eff ects Poisson regression.
Findings Between May 29, 2012 and May 31, 2014, we enrolled 697 infants who accrued 513 child-years of follow-up.
We recorded 141 pneumonia episodes, with an incidence of 0·27 episodes per child-year (95% CI 0·23–0·32). 32
(23%) pneumonia cases were severe pneumonia, with an incidence of 0·06 episodes per child-year (95% CI
0·04–0·08). Two (1%) of 141 pneumonia episodes led to death from pneumonia. Maternal HIV, maternal smoking,
male sex, and malnutrition were associated with an increased incidence of pneumonia.
Interpretation Pneumonia incidence was high in the fi rst year of life, despite a strong immunisation programme
including 13-valent pneumococcal conjugate vaccine. Incidence was associated with pneumonia risk factors that are
amenable to interventions. Prevention of childhood pneumonia through public health interventions to address these
risk factors should be strengthened.
Funding Bill & Melinda Gates Foundation, South African Thoracic Society, Federation of Infectious Diseases Societies
of South Africa, and University of Cape Town
Reaction mechanism of the direct gas phase synthesis of H2O2 catalyzed by Au3
The gas phase reaction of molecular oxygen and hydrogen catalyzed by a Au3cluster to yield H2O2 was investigated theoretically using second order Z-averaged perturbation theory, with the final energies obtained with the fully size extensive completely renormalized CR-CC(2,3) coupled clustertheory. The proposed reaction mechanism is initiated by adsorption and activation of O2 on the Au3cluster. Molecular hydrogen then binds to the Au3O2 global minimum without an energy barrier. The reaction between the activated oxygen and hydrogen molecules proceeds through formation of hydroperoxide (HO2) and a hydrogen atom, which subsequently react to form the product hydrogen peroxide. All reactants, intermediates, and product remain bound to the goldcluster throughout the course of the reaction. The steps in the proposed reaction mechanism have low activation energy barriers below 15kcal∕mol. The overall reaction is highly exothermic by ∼30kcal∕mol
Overview of NASA Behavioral Health and Performance Standard Measures
NASAs Human Research Program (HRP) is developing a set of Standard Measures for use in spaceflight and spaceflight analog environments to monitor the risks of long-duration missions on human health and performance, including behavioral health, individual and team performance, and social processes. Based on measures selected, developed, and tested under the NASA-funded Behavioral Core Measures project (PI: D.F. Dinges) as well as other projects from NASAs Human Factors & Behavioral Performance research portfolio, NASAs Behavioral Health & Performance (BHP) Laboratory is further evaluating the operational feasibility, acceptability, and validity of a multidisciplinary suite of objective, subjective, behavioral, and biological measures for monitoring monitor behavioral health, individual and team performance, and social processes over time. The inaugural generation of the NASA Behavioral Health & Performance (BHP) Standard Measures includes a neurocognitive test battery, actigraphy, physical proximity sensors, cardiovascular monitors, and subjective self-reports of mood, depression, and various team and social processes and performance outcomes
MRI radiomic features are independently associated with overall survival in soft tissue sarcoma
Purpose: Soft tissue sarcomas (STS) represent a heterogeneous group of diseases, and selection of individualized treatments remains a challenge. The goal of this study was to determine whether radiomic features extracted from magnetic resonance (MR) images are independently associated with overall survival (OS) in STS.
Methods and Materials: This study analyzed 2 independent cohorts of adult patients with stage II-III STS treated at center 1 (N = 165) and center 2 (N = 61). Thirty radiomic features were extracted from pretreatment T1-weighted contrast-enhanced MR images. Prognostic models for OS were derived on the center 1 cohort and validated on the center 2 cohort. Clinical-only (C), radiomics-only (R), and clinical and radiomics (C+R) penalized Cox models were constructed. Model performance was assessed using Harrell\u27s concordance index.
Results: In the R model, tumor volume (hazard ratio [HR], 1.5) and 4 texture features (HR, 1.1-1.5) were selected. In the C+R model, both age (HR, 1.4) and grade (HR, 1.7) were selected along with 5 radiomic features. The adjusted c-indices of the 3 models ranged from 0.68 (C) to 0.74 (C+R) in the derivation cohort and 0.68 (R) to 0.78 (C+R) in the validation cohort. The radiomic features were independently associated with OS in the validation cohort after accounting for age and grade (HR, 2.4;
Conclusions: This study found that radiomic features extracted from MR images are independently associated with OS when accounting for age and tumor grade. The overall predictive performance of 3-year OS using a model based on clinical and radiomic features was replicated in an independent cohort. Optimal models using clinical and radiomic features could improve personalized selection of therapy in patients with STS
OMAE2009-79934 JACK-UP INSTALLATION ON AN UNEVEN SEABED: RECOMMENDATIONS FROM MODEL TESTING IN OVERCONSOLIDATED CLAY
ABSTRACT This paper presents results of a laboratory testing program employing a reduced-scaled model of a three-legged jack-up to investigate the influence of an adjacent footprint on spudcan installation. This study focused on the installation of the full jack-up with a single leg located adjacent to a surface discontinuity. This contrasts previous studies that focused on the behavior of a single leg model and aims to account for the coupled interaction of the three legs and hull. The investigation was conducted using a 1:200 model scale jack-up designed to represent an average commonly used field jack-up. It was fully instrumented for leg bending and axial force measurement, and allowed unconstrained horizontal motion and rotation in the plane of foundation-footprint offset. Installation was performed at foundation-footprint centerline offsets of 0.75, 0.89, and 1.0 times the footprint diameter in overconsolidated kaolin clay adjacent to three different footprint types. The three footprint types -spudcan generated, a similarly shaped vertical walled auger generated, and shallow slope -were used to analyze separately the effect of shape and soil disturbance
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