1,989 research outputs found

    PolĂ­ticas pĂșblicas sobre economĂ­a solidaria en Ecuador

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    El presente estudio analiza las polĂ­ticas pĂșblicas que se han implementado a favor de la EconomĂ­a Solidaria en Ecuador, para lo cual, se parte de la propuesta conceptual que los autores españoles ChĂĄvez y MonzĂłn, especialistas en EconomĂ­a Social, han desarrollado en base a estudios de esta realidad en Europa, AmĂ©rica Latina y África por aproximadamente dos dĂ©cadas

    The Reflexivity of Explicit Performatives

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    The aim of this contribution is to propose a natural implementation of the reflexive-referential theory advanced by Perry 2001 that aims at accounting for the reflexive character of explicit performative utterances. This is accomplished by introducing a reflexive-performative constraint on explicit performatives

    Protons pump inhibitor treatment and lower gastrointestinal bleeding: Balancing risks and benefits

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    Proton pump inhibitors (PPIs) represent a milestone in the treatment of acid-related diseases, and are the mainstay in preventing upper gastrointestinal bleeding in high-risk patients treated with nonsteroidal antiinflammatory drugs (NSAIDs) or low-dose aspirin. However, this beneficial effect does not extend to the lower gastrointestinal tract. PPIs do not prevent NSAID or aspirin-associated lower gastrointestinal bleeding (LGB). PPIs may increase both small bowel injury related to NSAIDs and low-dose aspirin treatment and the risk of LGB. Recent studies suggested that altering intestinal microbiota by PPIs may be involved in the pathogenesis of NSAID-enteropathy. An increase in LGB hospitalization rates may occur more frequently in older patients with more comorbidities and are associated with high hospital resource utilization, longer hospitalization, and increased mortality. Preventive strategies for NSAID and aspirin-associated gastrointestinal bleeding should be directed toward preventing both upper and lower gastrointestinal damage. Future research should be directed toward identifying patients at low-risk for gastrointestinal events associated with the use of NSAIDs or aspirin to avoid inappropriate PPI prescribing. Alternatively, the efficacy of new pharmacologic strategies should be evaluated in high-risk groups, with the aim of reducing the risk of both upper and lower gastrointestinal bleeding in these patients

    Norms in deliberation: The role of the principles of justice and universalization in practical discourses on the justice of norms

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    Producción CientíficaDiscursive theories of justice have been questioned for putting forward high-level principles that should nevertheless play a role in practical discourses in which the justice of a claim is at stake. Here, I will critically examine and systematize the main tenets in Rawls’s and Habermas’s discursive theories, and will suggest that the principles of justice (Rawls) and universalization (Habermas) can and play the role of mandates of optimalization in real deliberations on justice
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