8,694 research outputs found
The effects of Bodymax high-repetition resistance training on measures of body composition and muscular strength in active adult women
This is the author's PDF version of an article published in Journal of strenght and conditioning research in 2003. The definitive version is available at http://www.nsca-jscr.orgThe purpose of this study was to investigate the effects of a light, high-repetition resistance-training program on skinfold thicknesses and muscular strength in women. Thirty-nine active women (mean age 38.64 +/- 4.97 years) were randomly placed into a resistance-training group (RT; n = 20) or a control group (CG; n = 19). The RT group performed a resistance-training program called Bodymax for 1 hour, 3 d.wk(-1), which incorporated the use of variable free weights and high repetitions in a group setting. The CG group continued its customary aerobic training for 1 hour 3 d.wk(-1). Five skinfold and 7 muscular strength measures were determined pretraining and after 12 weeks of training. Sum of skinfolds decreased (-17 mm; p < 0.004) and muscular strength increased (+57.4 kg; p < 0.004) in the RT group. Effect sizes for individual skinfold sites and strength measures were "medium" and "high," respectively. Bodymax is an effective resistance-training program for reducing skinfold thickness and increasing muscular strength in active women. Therefore, women with a similar or lower-activity status should consider incorporating such training into their regular fitness programs
The reproducibility of perceptually regulated exercise responses during short-term cycle ergometry
This is the author's PDF version of an article published in International journal of sports medicine in 2004. The definitive version is available at www.thieme-connect.com.The purpose of this study was to assess the reproducibility over four trials of perceptually regulated exercise intensity during short-term cycle ergometry. Recent research has suggested that an improvement in the reproducibility (better agreement) of the exercise output would be observed with a repeated practice of using regulatory tools such as Borg’s 6-20 rating of perceived exertion (RPE) scale. Eighteen healthy active volunteers (nine males mean age (± SD) 24.7 ± 3.4 yr, and nine females 27.6 ± 5.4 yr) completed four identical intermittent effort production trials on a cycle ergometer, over a period of two-three weeks, with all trials being between three and five days apart. After warm-up, the volunteers were asked to produce four x three-minute bouts of exercise at RPE levels: 13, 15, 9, and 17 (in this order). Power output (W), percentage maximum heart rate reserve (%MHRR), and oxygen consumption (VO2; ml•kg-1•min-1) were recorded in the final minute of each bout. Analysis revealed that the 95% limits of agreement (LoA) between repeated trials did not decrease for the objective markers of exercise intensity, remaining wide throughout. In the worst case comparisons the LoA represented changes (expressed as a proportion of the mean of two trials) of up to 58.3% in power output (T2 vs. T3 at RPE 9), 65.5% in %MHRR (T1 vs. T2 at RPE 13) and 36.5% in VO2 (T3 vs. T4 at RPE 17). These findings question the use of ratings of perceived exertion to regulate exercise effort. That the reproducibility of effort is also not seen to improve with practice raises doubts over the validity of using the RPE scale for providing training intensities for this type of exercise.This article was submitted to the RAE2008 for the University of Chester - Allied Health Professions and Studies
Development of microwave NDT inspection techniques for large solid propellant rocket motors Final report
Microwave nondestructive testing techniques for large solid propellant rocket engine
Imaging diagnosis-computed tomography of traction bronchiectasis secondary to pulmonary fibrosis in a Patterdale Terrier
An 8-year-old, Patterdale terrier was referred for evaluation of tachypnoea, exercise intolerance, and weight loss. Computed tomographic images showed pneumomediastinum, diffuse pulmonary ground glass opacity, and marked dilatation of peripheral bronchi, but no evidence of thickened bronchial walls. The histopathologic diagnosis was diffuse pulmonary interstitial fibrosis, type II pneumocyte hyperplasia, and bronchiectasis. The lack of evidence of primary bronchitis supported a diagnosis of traction bronchiectasis. Traction bronchiectasis can occur as a sequela to pulmonary fibrosis in dogs. (C) 2016 American College of Veterinary Radiology
Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency
Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria. For example, type 1–dependent control of malaria parasitemia might be impaired by the type 2 milieu of preexisting helminth infection. Alternatively, immunomodulatory effects of helminths might affect the likelihood of malarial immunopathology. Using rodent models of lymphatic filariasis (Litomosoides sigmodontis) and noncerebral malaria (clone AS Plasmodium chabaudi chabaudi), we quantified disease severity, parasitemia, and polyclonal splenic immune responses in BALB/c mice. We found that coinfected mice, particularly those that did not have microfilaremia (Mf), had more severe anemia and loss of body mass than did mice with malaria alone. Even when controlling for parasitemia, malaria was most severe in Mf coinfected mice, and this was associated with increased interferon-g responsiveness. Thus, in Mf mice, filariasis upset a delicate immunological balance in malaria infection and exacerbated malaria-induced immunopathology. Helminth infections are prevalent throughout tropical regions where malaria is transmitted [1–5]. Interactions among infections commonly alter disease severity [6, 7], and malaria-helminth coinfection can either exac
The Achilles tendon total rupture score : a study of responsiveness, internal consistency and convergent validity on patients with acute Achilles tendon ruptures
Background
The Achilles tendon Total Rupture Score was developed by a research group in 2007 in response to the need for a patient reported outcome measure for this patient population. Beyond this original development paper, no further validation studies have been published.
Consequently the purpose of this study was to evaluate internal consistency, convergent validity and responsiveness of this newly developed patient reported outcome measure within patients who have sustained an isolated acute Achilles tendon rupture.
Methods
Sixty-four eligible patients with an acute rupture of their Achilles tendon completed the Achilles tendon Total Rupture Score alongside two further patient reported outcome measures (Disability Rating Index and EQ 5D). These were completed at baseline, six weeks, three months, six months and nine months post injury. The Achilles tendon Total Rupture Score was evaluated for internal consistency, using Cronbach's alpha, convergent validity, through correlation analysis and responsiveness, by analysing floor and ceiling effects and calculating its relative efficiency in comparison to the Disability Rating Index and EQ 5D scores.
Results
The Achilles tendon Total Rupture Score demonstrated high internal consistency (Cronbachs alpha > 0.8) and correlated significantly (p < 0.001) with the Disability Rating Index at five time points (pre-injury, six weeks, three, six and nine months) with correlation coefficients between -0.5 and -0.9. However, the confidence intervals were wide. Furthermore, the ability of the new score to detect clinically important changes over time (responsiveness) was shown to be greater than the Disability Rating Index and EQ 5D.
Conclusions
A universally accepted outcome measure is imperative to allow comparisons to be made across practice. This is the first study to evaluate aspects of validity of this newly developed outcome measure, outside of the developing centre. The ATRS demonstrated high internal consistency and responsiveness, with limited convergent validity. This research provides further support for the use of this outcome measure, however further research is required to advocate its universal use in patients with acute Achilles tendon ruptures. Such areas include inter-rater reliability and research to determine the minimally clinically important difference between scores
Oxidative Heck desymmetrisation of 2,2-disubstituted cyclopentene-1,3-diones
Oxidative Heck couplings have been successfully developed for 2,2-disubstituted cyclopentene-1,3-diones. The direct coupling onto the 2,2-disubstituted cyclopentene-1,3-dione core provides a novel expedient way of enantioselectively desymmetrising all-carbon quaternary centres
Solar Magnetic Tracking. I. Software Comparison and Recommended Practices
Feature tracking and recognition are increasingly common tools for data
analysis, but are typically implemented on an ad-hoc basis by individual
research groups, limiting the usefulness of derived results when selection
effects and algorithmic differences are not controlled. Specific results that
are affected include the solar magnetic turnover time, the distributions of
sizes, strengths, and lifetimes of magnetic features, and the physics of both
small scale flux emergence and the small-scale dynamo. In this paper, we
present the results of a detailed comparison between four tracking codes
applied to a single set of data from SOHO/MDI, describe the interplay between
desired tracking behavior and parameterization of tracking algorithms, and make
recommendations for feature selection and tracking practice in future work.Comment: In press for Astrophys. J. 200
Physics of puffing and microexplosion of emulsion fuel droplets
The physics of water-in-oil emulsion droplet microexplosion/puffing has been investigated using high-fidelity interface-capturing simulation. Varying the dispersed-phase (water) sub-droplet size/location and the initiation location of explosive boiling (bubble formation), the droplet breakup processes have been well revealed. The bubble growth leads to local and partial breakup of the parent oil droplet, i.e., puffing. The water sub-droplet size and location determine the after-puffing dynamics. The boiling surface of the water sub-droplet is unstable and evolves further. Finally, the sub-droplet is wrapped by boiled water vapor and detaches itself from the parent oil droplet. When the water sub-droplet is small, the detachment is quick, and the oil droplet breakup is limited. When it is large and initially located toward the parent droplet center, the droplet breakup is more extensive. For microexplosion triggered by the simultaneous growth of multiple separate bubbles, each explosion is local and independent initially, but their mutual interactions occur at a later stage. The degree of breakup can be larger due to interactions among multiple explosions. These findings suggest that controlling microexplosion/puffing is possible in a fuel spray, if the emulsion-fuel blend and the ambient flow conditions such as heating are properly designed. The current study also gives us an insight into modeling the puffing and microexplosion of emulsion droplets and sprays.This article has been made available through the Brunel Open Access Publishing Fund
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