10 research outputs found
Genomic architecture and prediction of censored time-to-event phenotypes with a Bayesian genome-wide analysis
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
While recent advancements in computation and modelling have improved the analysis of complex traits, our understanding of the genetic basis of the time at symptom onset remains limited. Here, we develop a Bayesian approach (BayesW) that provides probabilistic inference of the genetic architecture of age-at-onset phenotypes in a sampling scheme that facilitates biobank-scale time-to-event analyses. We show in extensive simulation work the benefits BayesW provides in terms of number of discoveries, model performance and genomic prediction. In the UK Biobank, we find many thousands of common genomic regions underlying the age-at-onset of high blood pressure (HBP), cardiac disease (CAD), and type-2 diabetes (T2D), and for the genetic basis of onset reflecting the underlying genetic liability to disease. Age-at-menopause and age-at-menarche are also highly polygenic, but with higher variance contributed by low frequency variants. Genomic prediction into the Estonian Biobank data shows that BayesW gives higher prediction accuracy than other approaches
Markers of imminent myocardial infarction
- Author
- Asvold Bjorn Olav
- Butterworth Adam S.
- Elmstahl Solve
- Engstrom Gunnar
- Eriksson Karin Jensevik
- Fall Tove
- Ganna Andrea
- Gustafsson Stefan
- Hammar Ulf
- Hveem Kristian
- Ingelsson Erik
- Johansson Mattias
- Lall Kristi
- Lampa Erik
- Langhammer Arnulf
- Lind Lars
- Masala Giovanna
- Metspalu Andres
- Moreno-Iribas Conchi
- Nilsson Peter M.
- Perola Markus
- Simell Birgit
- Sipsma Hemmo
- Sundstrom Johan
- Svennblad Bodil
- Publication venue
- Publication date
- Field of study
SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Aims The aim of this study was to develop, validate, and illustrate an
updated prediction model (SCORE2) to estimate 10-year fatal and
non-fatal cardiovascular disease (CVD) risk in individuals without
previous CVD or diabetes aged 40-69 years in Europe.
Methods and results We derived risk prediction models using
individual-participant data from 45 cohorts in 13 countries (677 684
individuals, 30 121 CVD events). We used sex-specific and competing
risk-adjusted models, including age, smoking status, systolic blood
pressure, and total- and HDL-cholesterol. We defined four risk regions
in Europe according to country-specific CVD mortality, recalibrating
models to each region using expected incidences and risk factor
distributions. Region-specific incidence was estimated using CVD
mortality and incidence data on 10 776 466 individuals. For external
validation, we analysed data from 25 additional cohorts in 15 European
countries (1 133 181 individuals, 43 492 CVD events). After applying the
derived risk prediction models to external validation cohorts, C-indices
ranged from 0.67 (0.65-0.68) to 0.81 (0.76-0.86). Predicted CVD risk
varied several-fold across European regions. For example, the estimated
10-year CVD risk for a 50-year-old smoker, with a systolic blood
pressure of 140 mmHg, total cholesterol of 5.5 mmol/L, and
HDL-cholesterol of 1.3 mmol/L, ranged from 5.9% for men in low- risk
countries to 14.0% for men in very high-risk countries, and from 4.2%
for women in low-risk countries to 13.7% for women in very high-risk
countries.
Conclusion SCORE2-a new algorithm derived, calibrated, and validated to
predict 10-year risk of first-onset CVD in European populations-enhances
the identification of individuals at higher risk of developing CVD
across Europe
Donanemab in early symptomatic Alzheimer disease : the TRAILBLAZER-ALZ 2 randomized clinical trial
- Author
- Abreu Rafael
- Agarwal Pinky
- Aggarwal Puja
- Agronin Marc
- Allen Alison
- Altamirano Dario
- Alva Gustavo
- Andersen James
- Anderson Allan
- Anderson Donald
- Apostolova Liana G.
- Ardayfio Paul
- Arnold Jennifer
- Asada Takashi
- Aso Yasuhiro
- Atit Vikram
- Ayala Ricardo
- Badruddoja Michael
- Badzio-jagiello Hanna
- Bajacek Michal
- Barton David
- Bear David
- Benjamin Sabrina
- Bergeron Richard
- Bhatia Perminder
- Black Sandra
- Block Allan
- Bolouri Mohammad
- Bond Wendy
- Bouthillier Jean
- Brangman Sharon
- Brew Bruce
- Brisbin Sarah
- Brisken Toby
- Brodtmann Amy
- Brody Mark
- Brooks Dawn A.
- Brosch Jared
- Brown Celia
- Brownstone Paul
- Bukowczan Sylwia
- Burns Jeffrey
- Cabrera Alicia
- Capote Horace
- Carrasco Angel
- Cevallos Yepez Jose
- Chavez Eric
- Chertkow Howard
- Chyrchel-paszkiewicz Urszula
- Ciabarra Anthony
- Clemmons Edward
- Cohen Daniel
- Cohen Ian
- Cohen Robert
- Collins Emily C.
- Concha Mauricio
- Costell Brian
- Crimmins Denis
- Cruz-pagan Yvette
- Cueli Adolfo
- Cupelo Robert
- Czarnecki Maciej
- Darby David
- Dautzenberg P.l.j.
- De Deyn Peter Paul
- De La Gandara Jose
- Deck Kenneth
- Dibenedetto David
- Dibuono Mark
- Dinnerstein Eric
- Dirican Ahmet
- Dixit Shanker
- Dobryniewski Jacek
- Drake Ryan
- Drysdale Peter
- Duara Ranjan
- Duffy John
- Ellenbogen Aaron
- Evans Cynthia D.
- Faradji Victor
- Feinberg Marc
- Feldman Robert
- Fishman Simon
- Flitman Stephen
- Forchetti Concetta
- Fraga Ivonne
- Frank Andrew
- Frishberg Benjamin
- Fujigasaki
- Fukase Hiroyuki
- Fumero Ileana
- Furihata Kenichi
- Galloway Christopher
- Gandhi Rekha
- George Kristi
- Germain Marcel
- Gitelman Darren
- Goetsch Nicholas
- Goldfarb Danielle
- Goldstein Mark
- Goldstick Lawrence
- Gonzalez Rojas Yaneicy
- Goodman Ira
- Greeley David
- Griffin Carl
- Grigsby Eric
- Grosz Daniel
- Hafner Karl
- Hansson Oskar
- Hart David
- Henein Sam
- Herskowitz Brad
- Higashi Shinji
- Higashi Yasuto
- Ho Gilbert
- Hodgson Jonathan
- Hohenberg Mark
- Hollenbeck Larry
- Holub Richard
- Hori Tomokatsu
- Hort Jakub
- Ilkowski Jan
- Ingram K. Jennifer
- Isaac Mitchell
- Ishikawa Mitsunori
- Janu Lubos
- Johnston Mark
- Julio William
- Justiz William
- Kaga Tomotsugu
- Kakigi Tatsuya
- Kalafer Marvin
- Kamijo Mikiko
- Kaplan Jeffrey
- Karathanos Michael
- Katayama Sadao
- Kaul Siddharth
- Keegan Andrew
- Kerwin Diana
- Khan Arifulla
- Khan Uzma
- Kimura Noriyuki
- Kirk Gregory
- Klodowska Gabriela
- Kowa Hisatomo
- Kutz Christen
- Kwentus Joseph
- Lai Rosalyn
- Lall Ayesha
- Lawrence Mary
- Lee Elly
- Leon Ramon
- Linker Gary
- Lisewski Pawel
- Liss Jonathan
- Liu Collins
- Losk Scott
- Lu Ming
- Lukaszyk Ewelina
- Lynch Jennifer
- Macfarlane Stephen
- Macsweeney Josephine
- Mannering Nicholas
- Markovic Oto
- Marks Donald
- Masdeu Joseph
- Matsui Yutaka
- Matsuishi Kunitaka
- Mcallister Peter
- Mcconnehey Brock
- Mcelveen Alvin
- Mcgill Lora
- Mecca Adam
- Mega Michael
- Mensah Jason
- Mickielewicz Anatol
- Minaeian Artin
- Mintun Mark
- Mocherla Bharat
- Monkul Nery Emel Serap
- Murphy Cynthia
- Murphy Paul
- Nagashima Hirotaka
- Nair Anil
- Nair Malini
- Nardandrea John
- Nash Marshall
- Nasreddine Ziad
- Nishida Yoshihiko
- Norton Jeffrey
- Nunez Lazaro
- O'mahony John
- Ochiai Jun
- Ohkubo Takuya
- Okamura Yasuyuki
- Okorie Eugene
- Olivera Esteban
- Omidvar Omid
- Ortiz-Cruz Desiree
- Osowa Alexander
- Papka Michelle
- Parker Alicia
- Patel Ashok
- Patel Meenakshi
- Patel Paayal
- Patry Claude
- Peckham Elizabeth
- Pfeffer Michael
- Pietras Alison
- Plopper Michael
- Porsteinsson Anton
- Poulin Robitaille Raphael
- Prins Niels
- Puente Orlando
- Ratajczak Marcin
- Rhee Margaret
- Ritchie Craig
- Ritter Angela
- Rodriguez Ables Lilia
- Rodriguez Ramon
- Rojas Julio
- Ross Jeffrey
- Royer Paule
- Rubin Jay
- Russell David
- Rutgers Sterre Malou
- Rutrick Stephanie
- Sadowski Martin
- Safirstein Beth
- Sagisaka Takafumi
- Salloway Stephen
- Scharre Douglas
- Schneider Lon
- Schreiber Curtis
- Schrift Michael
- Schulz Paul
- Schwartz Harvey
- Schwartzbard Julie
- Scott John
- Selem Lissette
- Sethi Pramod
- Sha Sharon
- Sharlin Kenneth
- Sharma Sanjiv
- Shcherbinin Sergey
- Shiovitz Thomas
- Shiwach Rajinder
- Sims John R.
- Skovronsky Daniel M.
- Sladek Martin
- Sloan Bart
- Solomon Paul
- Solomon Paul
- Sorial Ehab
- Sosa Evelio
- Sparks JonDavid
- Stedman Mary
- Steen Susan
- Stein Lee
- Stolyar Arkadiy
- Stoukides John
- Sudoh Shinji
- Sutton James
- Syed Junaid
- Szigeti Kinga
- Tachibana Hisatsugu
- Takahashi Yuichi
- Tateno Amane
- Taylor James Dale
- Taylor Kelly
- Tcheremissine Oleg
- Thebaud Adly
- Thein Stephen
- Thurman Louise
- Toenjes Steven
- Toji Hiromasa
- Toma Misaki
- Tran Duc
- Tsujimoto Masashi
- Turner Raymond
- Uchiyama Akiyoshi
- Ussorowska Dorota
- Vaishnavi Sanjeev
- Valor Elena
- Vandersluis Joel
- Vasquez Alberto
- Velez Juan
- Verghese Cherian
- Vodickova-borzova Klaudia
- Wang Hong
- Watson David
- Weidman David
- Weisman David
- Wessels Alette M.
- White Alexander
- Willingham Katherine
- Winkel Izabela
- Winner Paul
- Winston Jaron
- Wolff Adam
- Yagi Hideo
- Yamamoto Hideki
- Yathiraj Sanjay
- Yoshiyama Yasumasa
- Zboch Marzena
- Zimmer Jennifer A.
- Publication venue
- Publication date
- 01/01/2023
- Field of study
SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe
- Author
- Achenbach Stephan
- Aleksandrova Krasimira
- Amiano Pilar
- Amouyel Philippe
- Andersson Jonas
- Bakker Stephan J. L.
- Beulens Joline W. J.
- Blaha Michael
- Blankenberg Stefan
- Bobak Martin
- Boer Jolanda M. A.
- Bolton Thomas
- Bonet Catalina
- Bonnet Fabrice
- Boutron-Ruault Marie-Christine
- Braaten Tonje
- Brenner Hermann
- Brunner Eric J.
- Brunner Fabian
- Brunstrom Mattias
- Buring Julie
- Butterworth Adam S.
- Capkova Nadezda
- Cesana Giancarlo
- Chrysohoou Christina
- Chung Ryan
- Colorado-Yohar Sandra
- Cook Nancy R.
- Cooper Cyrus
- Costa Rui Bebiano Da Providencia
- Dahm Christina C.
- Danesh John
- Davidson Karina
- De Bacquer Dirk
- de la Camara Agustin Gomez
- de Vries Tamar
- Dendale Paul
- Dennison Elaine
- Di Angelantonio Emanuele
- Di Castelnuovo Augusto
- Doerr Marcus
- Donfrancesco Chiara
- Dorresteijn Jannick
- Dorynska Agnieszka
- Eliasson Mats
- Engstrom Gunnar
- Ference Brian A.
- Ferrari Pietro
- Ferrario Marco
- Ford Ian
- Fu Michael
- Gansevoort Ron T.
- Giampaoli Simona
- Gillum Richard F.
- Graham Ian
- Grassi Guido
- Hageman Steven
- Halle Martin
- Hansson Per-Olof
- Huculeci Radu
- Hveem Kristian
- Iacoviello Licia
- Ikram M. Kamran
- Jorgensen Torben
- Joseph Bijoy
- Jousilahti Pekka
- Jukema J. Wouter
- Kaaks Rudolf
- Kaptoge Stephen
- Katzke Verena
- Kavousi Maryam
- Kee Frank
- Kiechl Stefan
- Klotsche Jens
- Koenig Wolfgang
- Kronmal Richard A.
- Kubinova Ruzena
- Kucharska-Newton Anna
- Kuulasmaa Kari
- Lall Kristi
- Lehmann Nils
- Leistner David
- Linneberg Allan
- Lora Pablos David
- Lorenz Thiess
- Lu Wentian
- Luksiene Dalia
- Lyngbakken Magnus
- Magnussen Christina
- Malyutina Sofia
- Marin Ibanez Alejandro
- Masala Giovanna
- Mathiesen Ellisiv B.
- Matsushita Kuni
- McEvoy John William
- Meade Tom W.
- Melander Olle
- Meyer Haakon E.
- Moons Karel G. M.
- Moreno-Iribas Conchi
- Muenzel Thomas
- Muller David
- Nikitin Yury
- Nordestgaard Borge G.
- Ojeda Francisco
- Omland Torbjorn
- Onland Charlotte
- Overvad Kim
- Packard Chris
- Pajak Andrzej
- Palmieri Luigi
- Panagiotakos Demosthenes
- Panico Salvatore
- Pennells Lisa
- Perez-Cornago Aurora
- Peters Annette
- Pietila Arto
- Pikhart Hynek
- Psaty Bruce M.
- Quarti-Trevano Fosca
- Quiros Garcia J. Ramon
- Riboli Elio
- Ridker Paul M.
- Rodriguez Beatriz
- Rodriguez-Barranco Miguel
- Rosengren Annika
- Roussel Ronan
- Sacerdote Carlotta
- Salomaa Veikko
- Sans Susana
- Sattar Naveed
- Schiborn Catarina
- Schmidt Boerge
- Schoettker Ben
- Schulze Matthias
- Schwartz Joseph E.
- Selmer Randi Marie
- Shea Steven
- Shipley Martin J.
- Sieri Sabina
- Soderberg Stefan
- Sofat Reecha
- Tamosiunas Abdonas
- Thorand Barbara
- Tillmann Taavi
- Timmis Adam
- Tjonneland Anne
- Tong Tammy Y. N.
- Trichopoulou Antonia
- Tumino Rosario
- Tunstall-Pedoe Hugh
- Tybjaerg-Hansen Anne
- Tzoulaki Joanna
- van der Heijden Amber
- van der Schouw Yvonne T.
- Vardas Panos
- Veronesi Giovanni
- Verschuren W. M. Monique
- Visseren Frank
- Voelzke Henry
- Waldeyer Christoph
- Wareham Nicholas J.
- Weiderpass Elisabete
- Weidinger Franz
- Wild Philipp
- Willeit Johann
- Willeit Peter
- Wilsgaard Tom
- Wood Angela
- Woodward Mark
- Xu Zhe
- Zeller Tanja
- Zhang Dudan
- Zhou Bin
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- Field of study
The trans-ancestral genomic architecture of glycemic traits
- Author
- Abecasis G. R. (Goncalo R.)
- Adair L. S. (Linda S.)
- Aguilar-Salinas C. A. (Carlos Alberto)
- Ahluwalia T. S. (Tarunveer S.)
- Alarcon-Riquelme M. E. (Marta E.)
- Amin N. (Najaf)
- An P. (Ping)
- Anasanti M. D. (Mila D.)
- Appel E. V. (Emil V. R.)
- Arzumanyan Z. (Zorayr)
- Astrup A. (Arne)
- Aviles-Santa L. (Larissa)
- Bakker S. J. (Stephan J. L.)
- Baldassarre D. (Damiano)
- Barroso I. (Ines)
- Becker D. M. (Diane M.)
- Beekman M. (Marian)
- Beilin L. J. (Lawrence J.)
- Bergman R. N. (Richard N.)
- Bergmann S. (Sven)
- Bertoni A. (Alain)
- Bielak L. F. (Lawrence F.)
- Bisgaard H. (Hans)
- Black C. (Corri)
- Blueher M. (Matthias)
- Boehm B. O. (Bernhard O.)
- Boehnke M. (Michael)
- Boerwinkle E. (Eric)
- Bonnelykke K. (Klaus)
- Bonnycastle L. L. (Lori L.)
- Boomsma D. I. (D. I.)
- Bornstein S. R. (Stefan R.)
- Bottinger E. P. (Erwin P.)
- Boutin T. S. (Thibaud S.)
- Bowden D. W. (Donald W.)
- Brody J. A. (Jennifer A.)
- Buchanan T. A. (Thomas A.)
- Burtt N. P. (Noel P.)
- Cabrera C. P. (Claudia P.)
- Cade B. E. (Brian E.)
- Cai Q. (Qiuyin)
- Campbell A. (Archie)
- Campbell H. (Harry)
- Canouil M. (Mickael)
- Caulfield M. J. (Mark J.)
- Chai J. F. (Jin Fang)
- Chai X. (Xiaoran)
- Chambers J. C. (John C.)
- Chan K. H. (Kei Hang Katie)
- Chang L.-C. (Li-Ching)
- Chang Y. C. (Yi Cheng)
- Chasman D. I. (Daniel I.)
- Chen B. H. (Brian H.)
- Chen C.-H. (Chien-Hsiun)
- Chen J. (Ji)
- Chen Y. I. (Yii-Der Ida)
- Cheng C.-Y. (Ching-Yu)
- Chitrala K. N. (Kumaraswamy Naidu)
- Chiu Y.-F. (Yen-Feng)
- Chu A. Y. (Audrey Y.)
- Claringbould A. (Annique)
- Collins F. S. (Francis S.)
- Corbin L. J. (Laura J.)
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- Cucca F. (Francesco)
- de Geus E. J. (Eco J. C.)
- de Haan H. G. (Hugoline G.)
- de Silva H. J. (H. Janaka)
- Dedoussis G. (George)
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- Delgado G. E. (Graciela E.)
- Demirkan A. (Ayse)
- Du S. (Shufa)
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- Fatumo S. A. (Segun A.)
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- Gayan J. (Javier)
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- Ichihara S. (Sahoko)
- Igase M. (Michiya)
- Ikram M. A. (M. Arfan)
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- Kawaguchi T. (Takahisa)
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- Kentistou K. A. (Katherine A.)
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- Kim Y. J. (Young Jin)
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- Kleber M. E. (Marcus E.)
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- Kumari M. (Meena)
- Kutalik Z. (Zoltan)
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- Kuusisto J. (Johanna)
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- Lai S. (Shuiqing)
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- Lam K. (Kelvin)
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- Li H. (Huaixing)
- Li M. (Man)
- Li-Gao R. (Ruifang)
- Ligthart S. (Symen)
- Lin S.-Y. (Shih-Yi)
- Lin X. (Xu)
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- Magi R. (Reedik)
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- Mahajan A. (Anubha)
- Mangino M. (Massimo)
- Marenne G. (Gaelle)
- Marzi C. (Carola)
- Matsubara T. (Tatsuaki)
- Matsuda F. (Fumihiko)
- McCarthy M. I. (Mark I.)
- Meigs J. B. (James B.)
- Metspalu A. (Andres)
- Mingrone G. (Geltrude)
- Mohlke K. L. (Karen L.)
- Montasser M. E. (May E.)
- Mooijaart S. (Simon)
- Mook-Kanamori D. O. (Dennis O.)
- Moon S. (Sanghoon)
- Moreno-Macias H. (Hortensia)
- Mori T. A. (Trevor A.)
- Morris A. P. (Andrew P.)
- Munroe P. B. (Patricia B.)
- Nabika T. (Toru)
- Nadkarni G. N. (Girish N.)
- Nadler J. L. (Jerry L.)
- Nag A. (Abhishek)
- Nakatochi M. (Masahiro)
- Ndungu A. (Anne)
- Nelis M. (Mari)
- Nelson S. C. (Sarah C.)
- Neville M. J. (Matt J.)
- Njolstad I. (Inger)
- Noce D. (Damia)
- Nolte I. M. (Ilja M.)
- Noordam R. (Raymond)
- Norris J. M. (Jill M.)
- North K. E. (Kari E.)
- O'Connell J. R. (Jeffrey R.)
- Ohyagi Y. (Yasumasa)
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- Padmanabhan S. (Sandosh)
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- Palmer N. D. (Nicholette D.)
- Parker S. C. (Stephen C. J.)
- Pedersen O. (Oluf)
- Pennell C. E. (Craig E.)
- Peters A. (Annette)
- Peyser P. A. (Patricia A.)
- Pistis G. (Giorgio)
- Polasek O. (Ozren)
- Porteous D. J. (David J.)
- Pramstaller P. P. (Peter P.)
- Preuss M. (Michael)
- Prokopenko I. (Inga)
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- Rich S. S. (Stephen S.)
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- Vangipurapu J. (Jagadish)
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- Verweij N. (Niek)
- Vestergaard H. (Henrik)
- Vitart V. (Veronique)
- Vogel M. (Mandy)
- Vollenweider P. (Peter)
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- Waage J. (Johannes)
- Wagenknecht L. E. (Lynne E.)
- Walker M. (Mark)
- Wang C. (Chaolong)
- Wang C. A. (Carol A.)
- Wang H. (Heming)
- Wang N. (Nan)
- Wang T. (Tao)
- Wang Y. (Yujie)
- Wang Y. X. (Ya X.)
- Wareham N. J. (Nick J.)
- Warren H. R. (Helen R.)
- Watanabe R. M. (Richard M.)
- Watkins H. (Hugh)
- Wei W. B. (Wen B.)
- Wen W. (Wanqing)
- Wheeler E. (Eleanor)
- Wickremasinghe A. R. (Ananda R.)
- Willems van Dijk K. (Ko)
- Willems S. M. (Sara M.)
- Willemsen G. (Gonneke)
- Wilsgaard T. (Tom)
- Wilson J. F. (James F.)
- Wong A. (Andrew)
- Wong T.-Y. (Tien-Yin)
- Wood A. R. (Andrew R.)
- Wu J.-Y. (Jer-Yuarn)
- Wu P. (Peitao)
- Wu Y. (Ying)
- Xiang A. H. (Anny H.)
- Xie T. (Tian)
- Yanek L. R. (Lisa R.)
- Yao J. (Jie)
- Yengo L. (Loic)
- Yokota M. (Mitsuhiro)
- Zafarmand M. H. (Mohammad Hadi)
- Zeggini E. (Eleftheria)
- Zemunik T. (Tatijana)
- Zhang W. (Weihua)
- Zhang X. (Xiaoshuai)
- Zhao J.-H. (Jing-Hua)
- Zhao W. (Wei)
- Zheng W. (Wei)
- Zonderman A. B. (Alan B.)
- Publication venue
- Springer Nature
- Publication date
- 01/01/2021
- Field of study
Abstract
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide association studies comprising up to 281,416 individuals without diabetes (30% non-European ancestry) for whom fasting glucose, 2-h glucose after an oral glucose challenge, glycated hemoglobin and fasting insulin data were available. Trans-ancestry and single-ancestry meta-analyses identified 242 loci (99 novel; P < 5 x 10-8), 80% of which had no significant evidence of between-ancestry heterogeneity. Analyses restricted to individuals of European ancestry with equivalent sample size would have led to 24 fewer new loci. Compared with single-ancestry analyses, equivalent-sized trans-ancestry fine-mapping reduced the number of estimated variants in 99% credible sets by a median of 37.5%. Genomic-feature, gene-expression and gene-set analyses revealed distinct biological signatures for each trait, highlighting different underlying biological pathways. Our results increase our understanding of diabetes pathophysiology by using trans-ancestry studies for improved power and resolution
COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19
- Author
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- M Bochud (7745951)
- M Filipovic (10653125)
- M Frischknecht (13566601)
- M Jaquet (13566502)
- M Oddo (13344315)
- M Papadimitriou-Olivgeris (13566538)
- M Rime (13566496)
- M Van Singer (13566556)
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- Maharun Chowdhury (13566874)
- Mahmoud Abdel-Aziz (13566391)
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- Mansour Almutairi (13231080)
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- Marco Gori (13566655)
- Marco Mandala (13566757)
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- Mari Kaunisto (443248)
- Maria Antonietta Mazzei (8467722)
- Maria Antonietta Mencarelli (9265094)
- Maria Bandini (13566706)
- Maria J Arranz (13567282)
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- Maria Palmieri (9265085)
- Maria Teresa La Rovere (10150877)
- Marie Coignet (13566220)
- Marie Thys (12405087)
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- Mario Umberto Mondelli (13566670)
- Marissa Zyndorf (13567009)
- Mark Daly (574908)
- Mark J Caulfield (7948367)
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- Marta Garcia-Clemente (13567279)
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- Matthew Solomonson (1565770)
- Matti Pirinen (415109)
- Mattia Cordioli (13566211)
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- May Alrashed (11773373)
- Meike Bartels (109714)
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- Menachem Zlatopolsky (13567036)
- Meriem Bouab (13566295)
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- Michael Chasse (13566316)
- Michael Gaddis (13566226)
- Michael Hultstrom (13567171)
- Michael N Cantor (13567063)
- Michael Peruggia (13567018)
- Michael Preuss (183175)
- Michel Georges (69807)
- Michel MG Nivard (13567084)
- Michel Moutschen (262488)
- Michelle Daya (458882)
- Mihael H Polymeropoulos (13567240)
- Miklos Lipcsey (70592)
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- Mirella Bruttini (9656614)
- Miriam Lucia Carriero (11885967)
- Miriana D'Alessandro (13566679)
- Mirjam Lista (13566667)
- Mohamed AF Hegazy (13566388)
- Mohamed R El-shanshory (13566406)
- Mohamed S Abd Elghafar (13566379)
- Mohamed S Torky (13566400)
- Mohammad Anwar (3524741)
- Mohammad S Fawzy (13567111)
- Mohammed A Eid (13566415)
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- Monica Poscente (13566799)
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- Nicolas Arning (5011661)
- Nicolas Tardif (13567174)
- Nicole Soranzo (12361)
- Nikolas Baya (13566181)
- Nils Koelling (13567219)
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- Nora Aljawini (13231071)
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- Noura S Abul-Husn (13567048)
- O Clerc (13566481)
- O Hugli (13566568)
- O Manuel (13566532)
- O Marchetti (13566484)
- O Pantet (13566574)
- Olav Rooyackers (269514)
- Olivier Malaise (421168)
- Olumide Adeleye (10905742)
- Opass Putchareon (13566955)
- Oreste De Vivo (13566754)
- Oyvind Helgeland (13567177)
- P Filippidis (13566520)
- P Montillier (13566631)
- P Vollenweider (7644698)
- Pajaree Chariyavilaskul (10136341)
- Paloma De La Cal-Sabater (13567303)
- Paloma Menendez-Valladares (13567333)
- Pamela Raggi (13566823)
- Panos Deloukas (21564)
- Paola Bergomi (9649394)
- Paola Petrocelli (13566853)
- Paolo Cameli (8467695)
- Paolo Di Domenico (13566847)
- Paolo Piacentini (10312815)
- Part Peterson (13566430)
- Pascale Huynen (13566271)
- Patrick Deelen (187548)
- Patrick Turley (7725947)
- Patrizia Zucchi (316158)
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- Paul M Ridker (7949642)
- Paul Naaber (7116242)
- Paul O'Reilly (614014)
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- Philippe Leonard (13566274)
- Pier Giorgio Scotton (13566742)
- Pierpaolo Parravicini (13566763)
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- Pierre-Yves Bochud (205597)
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- Pimpayao Sodsai (9931517)
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- PY Bochud (13566514)
- Qin Qin Huang (4166860)
- R Friolet (13566469)
- R Merlet Viollet (13566505)
- Rachel G Liao (13566160)
- Rafael de Cid (5998061)
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- Raffaele Scala (7024661)
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- Rahul Gupta (358711)
- Raili Allos (13566436)
- Rana Hasanato (13567123)
- Rasoul Aliannejad (10054106)
- Ravaglia Sabrina (13566802)
- Raymond Chung (1955386)
- Raymond K Walters (13566184)
- Reedik Magi (61757)
- Renato Polimanti (3043917)
- Renzo Scaggiante (6104627)
- Riccardo Colombo (94203)
- Richard C Trembath (9257558)
- Richard H Scott (13567189)
- Richard J Packer (11075223)
- Rita Perna (13566829)
- Roaa T Halawani (13567141)
- Robert C Free (8880545)
- Robert C Green (13566985)
- Robert Frithiof (348314)
- Robert P Sebra (13567000)
- Robert Warmerdam (13566973)
- Roberta Russo (587655)
- Robin Lerner (13566895)
- Roger Colobran (824193)
- Ron Do (201540)
- Rosangela Artuso (13566787)
- Rossella Tita (9265091)
- Rui Li (4631)
- Ruth JF Loos (3810124)
- Ryan C Thompson (13566994)
- S Estoppey Younes (13566583)
- S Foucras (13566493)
- S Gonseth Nussle (13566577)
- Sabine Claassen (13566256)
- Sabino Scolletta (65043)
- Sabrina Ravaglia (6410091)
- Saeideh Ahmadi (13566940)
- Salam Massadeh (6628496)
- Saleh Alqahtani (3315315)
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- Sam Choi (1977952)
- Sameer Chavan (3947117)
- Sameera AlJohani (3632836)
- Sami Koskelainen (13566451)
- Samina Ashraf (13566868)
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- Sang Hyuck Lee (13566892)
- Sanni Ruotsalainen (13566448)
- Sara Alotaibi (13567108)
- Sara Amitrano (9656605)
- Sara Pigazzini (13566247)
- Sarah Alkwai (13567126)
- Sarah Finer (237152)
- Sarah G Earle (13567204)
- Sauro Luchi (13566805)
- Saverio Giuseppe Parisi (4026326)
- Scott T Weiss (9407556)
- Sebastian Garcia-Madrona (13567324)
- Sebastian Zollner (13566925)
- Semira Gonseth Nussle (13566460)
- Serafina Valente (3753733)
- Serena Ludovisi (13566814)
- Serghei Mangul (4973068)
- Sergio Daga (11283239)
- Seyed Behrooz Mohseni Moghaddam (13566943)
- Shaheen Akhtar (192582)
- Shang-Kuan Lin (13567207)
- Shannon McCurdy (11944312)
- Shapna Hussain (13566886)
- Shawn N Murphy (4802670)
- Shawneequa Callier (13567228)
- Shea J Andrews (13566199)
- Shefa Miah (13566901)
- Shefali S Verma (13567090)
- Shona M Kerr (8950520)
- Silvia Baroni (2156290)
- Silvia Cappelli (13566712)
- Silvia Rojo (13567306)
- Simona Dei (13566808)
- Simona Marcantonio (9656611)
- Simona Sarzi-Braga (13566784)
- Simone Furini (173392)
- Slayton J Underwood (13566208)
- Sophie Venturelli (9326809)
- Souad Rahmouni (320501)
- Spencer Knight (13566223)
- Stefania Mantovani (202342)
- Stefano Baratti (13566817)
- Stefano Busani (735718)
- Stefano Ceri (3614225)
- Stefano Rusconi (237803)
- Stephanie Bibert (316131)
- Stephanie Gofflot (790863)
- Stephen J Wicks (13566349)
- Steven Ascolillo (13566991)
- Stuart C Sealfon (13566205)
- Sulggi Lee (5979596)
- Susan Walker (469919)
- Susanna Croci (11283263)
- Susanna Guerrini (13566682)
- T Brahier (13566565)
- T Egger (13566625)
- T Rochat Negro (13566613)
- Tala Abdullah (10905739)
- Tamer A Elhadidy (13566376)
- Tess Levy (11503363)
- Thanyawee Puthanakit (615421)
- Thitima B Suttichet (13566961)
- Tim D Spector (8543481)
- Tiziana Bachetti (361249)
- Tom Fowler (3624713)
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- Tomislav Maricic (178988)
- Tomoko Nakanishi (344291)
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- Tooraj Mirshahi (547507)
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- Triin Laisk (6103775)
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- V D'Acremont (13566580)
- V Eric Kerchberger (13566334)
- V Suttels (13566547)
- Valentina Anemoli (13566724)
- Vasilios Polymeropoulos (13567237)
- Veronica Rico (13567261)
- Veronica Robles (7338719)
- Veronique Erard (13566466)
- Victor Moreno (748751)
- Vijay G Sankaran (13566175)
- Vincent Mooser (47546)
- Vincenzo Forgetta (756326)
- Voraphoj Nilaratanakul (13566964)
- Vorasuk Shotelersuk (581000)
- Walaa A Felemban (13567150)
- Walaa M El-Lawaty (13566397)
- Walid T Khafaga (13566394)
- Wanna Chetruengchai (9659225)
- Wanying Zhu (1567963)
- Watsamon Jantarabenjakul (9504660)
- WC Albrich (13566586)
- Wei Zhou (24328)
- Wenhan Lu (8908976)
- Werner Albrich (5541584)
- Xavier Farre (10317580)
- Xiao Chang (43560)
- Xiaoqing Xue (6116318)
- Xueyang Wang (6813818)
- Y Lannepoudenx (13566508)
- Yan Sun (22436)
- Yaseen M Arabi (12041017)
- Yasmine Belhaj (13566250)
- Yasser M El-Sherbiny (13566358)
- Yen-Chen Anne Feng (9983636)
- Yuk-Lam Ho (7010873)
- Yuki Bradford (496693)
- Yunsung Lee (10670517)
- Yuval Itan (260527)
- Yves Beguin (264097)
- Zaman Afrasiabi (10905751)
- Zeinab Naderpour (10054118)
- Ziab Z Alahmadey (13567144)
- Publication venue
- Publication date
- 03/08/2022
- Field of study
The COVID-19 pandemic continues to pose a major public health threat, especially in countries with low vaccination rates. To better understand the biological underpinnings of SARS-CoV-2 infection and COVID-19 severity, we formed the COVID-19 Host Genetics Initiative1. Here we present a genome-wide association study meta-analysis of up to 125,584 cases and over 2.5 million control individuals across 60 studies from 25 countries, adding 11 genome-wide significant loci compared with those previously identified2. Genes at new loci, including SFTPD, MUC5B and ACE2, reveal compelling insights regarding disease susceptibility and severity.</p
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
- Author
- Abaitua Fernando
- Abecasis Goncalo
- Adair Linda S.
- Adeyemo Adebowale
- Aguilar-Salinas Carlos A.
- Ahmad Meraj
- Ahsan Habibul
- Akiyama Masato
- An Ping
- Anand Sonia S.
- Becker Diane M.
- Below Jennifer E.
- Bertoni Alain
- Bharadwaj Dwaipayan
- Bian Zheng
- Bielak Lawrence F.
- Boehnke Michael
- Bork-Jensen Jette
- Bottinger Erwin P.
- Bowden Donald W.
- Bragg Fiona
- Brandslund Ivan
- Brody Jennifer A.
- Brummett Chad M.
- Buchanan Thomas A.
- Cade Brian E.
- Canouil Mickael
- Chai Jin-Fang
- Chambers John C.
- Chan Juliana C. N.
- Chandak Giriraj R.
- Chang Li-Ching
- Chee Miao-Li
- Chen Chien-Hsiun
- Chen Guanjie
- Chen Ji
- Chen Shyh-Huei
- Chen Wei-Min
- Chen Yii-Der Ida
- Chen Yuan-Tsong
- Chen Zhengming
- Cheng Ching-Yu
- Chiou Joshua
- Cho Yoon Shin
- Choi Hyeok Sun
- Chuang Lee-Ming
- Collins Francis S.
- Cook James P.
- Cruz Miguel
- Cushman Mary
- Das Swapan K.
- de Silva H. Janaka
- Dedoussis George
- Dehghan Abbas
- Dimitrov Latchezar
- Doumatey Ayo P.
- Du Shufa
- Duan Qing
- Dupuis Josee
- Eckardt Kai-Uwe
- Emery Leslie S.
- Engert James C.
- Evans Daniel S.
- Evans Michele K.
- Ferrer Jorge
- Fischer Krista
- Flanagan Jack
- Florez Jose C.
- Floyd James S.
- Ford Ian
- Fornage Myriam
- Franco Oscar H.
- Frayling Timothy M.
- Freedman Barry, I
- Froguel Philippe
- Fuchsberger Christian
- Gaulton Kyle J.
- Genter Pauline
- Gerstein Hertzel C.
- Giedraitis Vilmantas
- Gieger Christian
- Gloyn Anna L.
- Gonzalez-Villalpando Clicerio
- Gonzalez-Villalpando Maria Elena
- Goodarzi Mark O.
- Gordon-Larsen Penny
- Gorkin David
- Graff Mariaelisa
- Grallert Harald
- Grarup Niels
- Groop Leif
- Gross Myron
- Guo Xiuqing
- Guo Yu
- Hackinger Sophie
- Hai Yang
- Haiman Christopher A.
- Han Sohee
- Hanis Craig L.
- Hansen Torben
- Hattersley Andrew T.
- Hayes M. Geoffrey
- Herder Christian
- Horikoshi Momoko
- Howard Annie-Green
- Hsueh Willa
- Huang Mengna
- Huang Wei
- Huerta-Chagoya Alicia
- Hung Yi-Jen
- Hwang Mi Yeong
- Hwu Chii-Min
- Ichihara Sahoko
- Igase Michiya
- Ikram Mohammad Arfan
- Ingelsson Erik
- Ingelsson Martin
- Ipp Eli
- Islam Md Tariqul
- Isono Masato
- Jang Hye-Mi
- Jasmine Farzana
- Jensen Richard A.
- Jiang Guozhi
- Jonas Jost B.
- Joo Yoonjung Yoonie
- Jorgensen Marit E.
- Jorgensen Torben
- Jukema J. Wouter
- Kabagambe Edmond K.
- Kadowaki Takashi
- Kals Mart
- Kamatani Yoichiro
- Kandeel Fouad R.
- Kardia Sharon L. R.
- Kasturiratne Anuradhani
- Kato Norihiro
- Katsuya Tomohiro
- Kaur Varinderpal
- Kawaguchi Takahisa
- Keaton Jacob M.
- Kho Abel N.
- Khor Chiea-Chuen
- Kibriya Muhammad G.
- Kim Bong-Jo
- Kim Duk-Hwan
- Kim Young Jin
- Kitajima Hidetoshi
- Koh Woon-Puay
- Kohara Katsuhiko
- Kooner Jaspal S.
- Kooperberg Charles
- Kottgen Anna
- Kriebel Jennifer
- Kronenberg Florian
- Kuusisto Johanna
- Kwak Soo-Heon
- Laakso Markku
- Lall Kristi
- Lamri Amel
- Lange Leslie A.
- Langenberg Claudia
- Lecoeur Cecile
- Lee Jung-Jin
- Lee Juyoung
- Lee Myung-Shik
- Lee Nanette R.
- Leong Aaron
- Li Liming
- Li Yun
- Li-Gao Ruifang
- Ligthart Symen
- Lim Victor J. Y.
- Lin Kuang
- Lind Lars
- Lindgren Cecilia M.
- Linneberg Allan
- Liu Ching-Ti
- Liu Jianjun
- Liu Simin
- Liu Yongmei
- Locke Adam E.
- Loh Marie
- Long Jirong
- Loos Ruth J. F.
- Louie Tin
- Luan Jian'an
- Luk Andrea O.
- Luo Xi
- Lv Jun
- Lyssenko Valeriya
- Ma Ronald C. W.
- Maeda Shiro
- Magi Reedik
- Mahajan Anubha
- Mamakou Vasiliki
- Mani K. Radha
- Matsuda Fumihiko
- McCarthy Mark, I
- McKean-Cowdin Roberta
- Meigs James B.
- Meitinger Thomas
- Mercader Josep M.
- Metspalu Andres
- Miguel-Escalada Irene
- Millwood Iona Y.
- Mohlke Karen L.
- Mook-Kanamori Dennis O.
- Moon Sanghoon
- Morris Andrew D.
- Morris Andrew P.
- Motala Ayesha A.
- Myers Simon R.
- Nadkarni Girish N.
- Nadler Jerry L.
- Nakatochi Masahiro
- Nalls Michael A.
- Nano Jana
- Nayak Uma
- Ng Maggie C. Y.
- Nicolas Aude
- Nongmaithem Suraj S.
- Noordam Raymond
- North Kari E.
- Nousome Darryl
- Ntalla Ioanna
- Okada Yukinori
- Orozco Lorena
- Palmer Colin N. A.
- Pan Ian
- Pankow James S.
- Pare Guillaume
- Park Kyong-Soo
- Parolo Pietro della Briotta
- Parra Esteban J.
- Patel Sanjay R.
- Pedersen Oluf
- Pereira Mark A.
- Peters Annette
- Petty Lauren E.
- Peyser Patricia A.
- Pirie Fraser J.
- Porneala Bianca
- Prasad Gauri
- Preissl Sebastian
- Preuss Michael H.
- Prins Bram Peter
- Province Michael A.
- Psaty Bruce M.
- Raffel Leslie J.
- Raffield Laura M.
- Rasmussen-Torvik Laura J.
- Rayner Nigel W.
- Redline Susan
- Reiner Alexander P.
- Rich Stephen S.
- Robertson Neil R.
- Roden Michael
- Rohde Rebecca
- Roll Kathryn
- Rotimi Charles N.
- Rotter Jerome, I
- Rueger Sina
- Sabanayagam Charumathi
- Sale Michele M.
- Saleheen Danish
- Sander Maike
- Sandow Kevin
- Sarnowski Chloe
- Sattar Naveed
- Schmidt Ellen M.
- Schonherr Sebastian
- Schurmann Claudia
- Scott Robert A.
- Shahriar Mohammad
- Sheu Wayne H. H.
- Shi Jinxiu
- Shin Dong Mun
- Shriner Daniel
- Shu Xiao-Ou
- Sim Xueling
- Smith Jennifer A.
- So Wing Yee
- Sofer Tamar
- Speidel Leo
- Spracklen Cassandra N.
- Stancakova Alena
- Stefansson Kari
- Steinthorsdottir Valgerdur
- Stilp Adrienne M.
- Strauch Konstantin
- Sun Meng
- Suzuki Ken
- Tabara Yasuharu
- Tai E-Shyong
- Tajuddin Salman
- Takahashi Atsushi
- Takeuchi Fumihiko
- Taliun Daniel
- Tam Claudia H. T.
- Tan Jingyi
- Taylor Kent D.
- Thorand Barbara
- Thorleifsson Gudmar
- Thorsteinsdottir Unnur
- Tomlinson Brian
- Tong Lin
- Torres Jason M.
- Trompet Stella
- Tsai Fuu-Jen
- Tuomilehto Jaakko
- Tusie-Luna Teresa
- Udler Miriam S.
- Valladares-Salgado Adan
- van Dam Rob M.
- van Dijk Ko Willems
- van Klinken Jan B.
- Varma Rohit
- Vujkovic Marijana
- Wacher-Rodarte Niels
- Walters Robin G.
- Wang Ya-Xing
- Wareham Nicholas J.
- Wheeler Eleanor
- Whitsel Eric A.
- Wickremasinghe Ananda R.
- Wilson James G.
- Witte Daniel R.
- Wong Tien-Yin
- Wu Jer-Yuarn
- Wuttke Matthias
- Xiang Anny H.
- Yajnik Chittaranjan S.
- Yamamoto Ken
- Yamauchi Toshimasa
- Yanek Lisa R.
- Yao Jie
- Yengo Loic
- Yokota Mitsuhiro
- Yoon Kyungheon
- Yu Canqing
- Yu Grace Z.
- Yuan Jian-Min
- Yusuf Salim
- Zeggini Eleftheria
- Zhang Liang
- Zhang Weihua
- Zheng Wei
- Zonderman Alan B.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
- Author
- Adair Linda S.
- Adeyemo Adebowale
- Aguilar-Salinas Carlos A.
- Ahlqvist Emma
- Ahluwalia Tarunveer S.
- Ahsan Habibul
- An Ping
- Anand Sonia S.
- Arruda Ana Luiza
- Becker Diane M.
- Below Jennifer E.
- Bertoni Alain
- Bharadwaj Dwaipayan
- Bielak Lawrence F.
- Bocher Ozvan
- Boehnke Michael
- Bonnefond Amelie
- Bork-Jensen Jette
- Bowden Donald W.
- Bragg Fiona
- Brandslund Ivan
- Broadaway K. Alaine
- Brody Jennifer A.
- Buchanan Thomas A.
- Burant Charles F.
- Butterworth Adam S.
- Cade Brian E.
- Canouil Mickael
- Chai Jin-Fang
- Chambers John C.
- Chan Juliana C. N.
- Chandak Giriraj R.
- Chang Kyong-Mi
- Chang Li-Ching
- Chee Miao-Li
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- Publication venue
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A first update on mapping the human genetic architecture of COVID-19
- Author
- Abd Elghafar Mohamed S.
- Abdel-Aziz Mahmoud
- Abdollahi Hamed
- Abdullah Tala
- Abecasis Goncalo R.
- Abedalthagafi Malak
- Abu Safieh Leen
- Abul-Husn Noura S.
- Acquilini Donatella
- Adams Emma L.
- Adamsara Alireza
- Adeleye Olumide
- Adra Darin
- Afilalo Jonathan
- Afilalo Marc
- Afrasiabi Zaman
- Aguero Daiana
- Ahmadi Saeideh
- Akhtar Shaheen
- Aksentijevich Alexandra
- Al Harthi Fawz
- Al Mutairi Amal
- Al-Afghani Hani
- Al-Awdah Laila
- Alaamery Manal
- Alahmadey Ziab Z.
- Alaverdian Diana
- Alavere Helene
- Albader Anoud
- Albaiceta Guillermo M.
- Albakri Jehad K.
- AlBardis Hadeel
- Albeladi Maha
- Albesher Nour
- Albrich W. C.
- Albrich Werner
- AlDhawi Nouf
- Aleagha Afshar Etemadi
- Alghamdi Bader
- Alghamdi Jahad
- Ali Altaf
- Aliannejad Rasoul
- Aljawini Nora
- AlJohani Sameera
- Alkwai Sarah
- Allos Raili
- AlMalik Abdulaziz
- Almalki Faisal
- Almohammed Iman
- Almutairi Mansour
- Alotaibi Sara
- Alowayn Albandary M.
- Alqahtani Saleh
- Alqubaishi Fatimah
- Alrashed May
- Alshareef Abdulraheem
- Alsolm Ebtehal
- Alswailm Moneera
- AlZahrani Deema
- Amirsavadkouhi Ali
- Amitrano Sara
- Andolfo Immacolata
- Andretta Francesca
- Andreucci Elena
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- Anedda Federico
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- Annis Aubrey
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- Anwar Mohammad
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- Armstrong Jacob
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- Arumugam Prabhu
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- Ruiz Luong
- Ruiz-Jaen Francisca
- Ruotsalainen Sanni
- Rusconi Stefano
- Russo Roberta
- Sabrina Ravaglia
- Saeedi Morteza
- Safa Nishat
- Salerni Lorenzo
- Salib Irene
- Samir Amr
- Sanarico Maurizio
- Sanguinetti Maurizio
- Sankaran Vijay G.
- Sarma Gopal
- Sarzi-Braga Simona
- Satterstrom F. Kyle
- Sauvage Anne-Sophie
- Sawaji Mona
- Scaggiante Renzo
- Scala Raffaele
- Schadt Eric E.
- Schiaroli Elisabetta
- Schurr Erwin
- Scolletta Sabino
- Scott Richard H.
- Scotton Pier Giorgio
- Sealfon Stuart C.
- Sebra Robert P.
- Seed Cotton
- Segala Francesco Vladimiro
- Segura Tomas
- Serra-Llovich Alex
- Serrano-Heras Gemma
- Sesso Howard D.
- Shahin Doaa
- Sharififard Bahareh
- Shaw Douglas M.
- Shortt Jonathan
- Shotelersuk Vorasuk
- Shrine Nick
- Siano Matteo
- Sloofman Laura G.
- Smieszek Sandra P.
- Smith Albert, V
- Smoller Jordan W.
- Sobh Ali
- Sodsai Pimpayao
- Soler Pere
- Solligard Erik
- Solomonson Matthew
- Soranzo Nicole
- Soriano Alex
- Spargi Genni
- Spector Tim D.
- Spencer Chris C. A.
- Spertilli Chiara
- Squeo Gabriella Maria
- Starkopf Joel
- Stella Alessandra
- Stevens Christine
- Stuckey Alex
- Suardi Claudia
- Suchartlikitwong Pintip
- Suh N.
- Suh Noemie
- Suliman Bandar A.
- Sumoy Lauro
- Sun Yan, V
- Suttels V
- Suttichet Thitima B.
- Tabri Jekaterina
- Tacconi Danilo
- Tadi Hengameh Ansari
- Tadini E.
- Tahmasebi Farah
- Tamm Anu
- Tanfoni Marco
- Tang Lara
- Tardif Nicolas
- Tavecchia Luisa
- Tenesa Albert
- Thompson Ryan C.
- Thys Marie
- Timmers Paul R. H. J.
- Tiseo Giusy
- Tita Rossella
- Tobin Martin D.
- Tommasi Andrea
- Torky Mohamed S.
- Torrents David
- Torvorapanit Pattama
- Trankiem Amy
- Trembath Richard C.
- Trivedi Bhavi
- Trogstad Lill-Iren S.
- Trotta Tullio
- Tsao Phil
- Tschopp J.
- Tselios Chris
- Tsuo Kristin
- Tumbarello Mario
- Turley Patrick
- Uitterlinden Andre G.
- Underwood Slayton J.
- Vaghi Massimo
- Valente Serafina
- Valentino Floriana
- van Blokland Irene
- van Heel David
- van Heel David A.
- Van Singer M.
- Vecchia Marco
- Veerapen Kumar
- Venn Laura D.
- Venturelli Sophie
- Vergori Alessandra
- Verma Anurag
- Verma Shefali S.
- Verzuri Agnese
- Viala B.
- Villalonga Joan Montaner
- Vincenti Antonella
- Viollet R. Merlet
- Voide Cathy
- Vollenweider P.
- Von Frenckell Christian
- von Hohenstaufen Kathrin Aprile
- von Mering C.
- Vonk Judith M.
- Vulesevic Branka
- Wain Louise, V
- Walker Susan
- Walters Raymond K.
- Wang Jiongming
- Wang Xueyang
- Warmerdam Robert
- Weiss Scott T.
- Wicks Stephen J.
- Willer Cristen
- Williams Alexander T.
- Wilson Daniel J.
- Wilson James F.
- Wolford Brooke
- Woolley Ann E.
- Wozniak H.
- Wright John
- Wyllie David H.
- Xue Xiaoqing
- Yadav Ashish
- Yassen Amr M.
- Younes S. Estoppey
- Zanella Isabella
- Zeberg Hugo
- Zguro Kristina
- Zhang Miao
- Zhao Jing Hua
- Zhou Wei
- Zhu Wanying
- Zlatopolsky Menachem
- Zollner Sebastian
- zu Bentrup F. Meyer
- Zucchi Patrizia
- Zyndorf Marissa
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study