5 research outputs found
Presi贸n venosa central, tiempo de recalentamiento y l铆quidos totales son factores postoperatorios de morbi-mortalidad en cirug铆a cardiaca
Producci贸n Cient铆ficaOBJETIVOS: Analizar la influencia de factores del postoperatorio
inmediato (primer d铆a), como posibles marcadores
de la evoluci贸n postoperatoria en los enfermos
operados de cirug铆a cardiaca.
PACIENTES Y M脡TODOS: Se dise帽贸 un estudio transversal
en el que se incluyeron consecutivamente pacientes
intervenidos de cirug铆a cardiaca. Se analiz贸 el efecto de
la presi贸n venosa central, el tiempo de recalentamiento
hasta alcanzar los 35,5潞C de temperatura central y los
l铆quidos totales administrados en 24 horas, sobre la mortalidad
y las complicaciones cardiacas, pulmonares y
renales.
RESULTADOS: Se incluyeron 236 pacientes. Se observ贸
que la presi贸n venosa central mayor de 18 mmHg, el
tiempo de recalentamiento mayor de 6 horas y la administraci贸n
de l铆quidos mayores a 5 litros durante las primeras
24 horas, se asoci贸 a un incremento de la mortalidad
y a la aparici贸n de complicaciones cardiovasculares,
pulmonares y renales.
CONCLUSIONES: La presi贸n venosa central, el tiempo
de recalentamiento y los l铆quidos administrados durante
el primer d铆a son determinantes de la evoluci贸n postoperatoria
Los factores motivacionales y competencias laborales en una entidad de producci贸n y venta de gases industriales, Cusco 2021
El presente trabajo de investigaci贸n tuvo como objetivo determinar el grado de relaci贸n de
los factores motivacionales con las competencias laborales de los trabajadores de una
entidad de producci贸n y venta de gases industriales, Cusco 2021; el estudio fue de enfoque
cuantitativo, de tipo aplicada, de dise帽o no experimental, la muestra fue censal, la poblaci贸n
estuvo compuesta por 33 trabajadores, la t茅cnica de recolecci贸n de datos fue la encuesta,
en la que se pudo concluir que: El grado de relaci贸n de los factores motivacionales con las
competencias laborales de los trabajadores, alcanz贸 un nivel de significancia de p<0,05,
por ello existe una correlaci贸n entre las variables de estudio en 0,736; la relaci贸n existente
entre la dimensi贸n factores motivacionales intr铆nsecos con las competencias laborales de
los trabajadores, tuvo una significancia de p<0,05, el valor del coeficiente de la dimensi贸n
de factores motivacionales intr铆nsecos y las competencias laborales fue 0,634 de valor de
relaci贸n, la relaci贸n existente entre la dimensi贸n factores motivacionales extr铆nsecos con
las competencias laborales de los trabajadores, tuvo una significancia de p<0,05, el valor
del coeficiente de la dimensi贸n de factores motivacionales intr铆nsecos y las competencias
laborales fue 0,481 valor moderado
Self-reported drug allergies and the diagnostic work-up in the surgical population
Producci贸n Cient铆ficaObjective The diagnostic work-up of a drug hypersensitivity reaction is indeed difficult. In
general, medical documentation of allergic reactions in medical reports is usually highly
deficient or non-existent. The aim of this study was to analyse the prevalence of selfreported
drug allergies in the surgical population as well as the criteria used in the diagnosis
of drug hypersensitivity reactions.
Methods A prospective study with the consecutive participation of 1439 patients, following
surgical intervention, attended the Post-Operative Care Unit. Previously, as a routine
process during the pre-anesthesia consultation, all patients were questioned about whether
they had any drug allergies to report and diagnostic work-up.
Results The prevalence of self-reported drug allergies was 8.3% (119/1439): 3.6% considered
themselves allergic to b-lactams and 2.4% to non-steroidal anti-inflammatory
drugs. Approximately one-third of the subjects (40 out of the 119) had not been subjected
to any allergy diagnostic procedure and with 79 (66.4%), the only diagnostic test used by
the Allergy Unit had been the skin prick-test. None of those participating in the study had
tryptase, methylhistamine, specific IgE or intradermal tests carried out to characterize the
diagnosis of the allergic reaction.
Conclusions These results show that self-reported drug allergies are highly prevalent and
as yet little explored. It is an important prevalence which should bring about modifications
to the prescription of certain medicaments. The medical personnel must be made aware of
the need to make an accurate diagnosis of allergies to medicaments
Genetic polymorphisms located in TGFB1, AGTR1, and VEGFA genes are associated to chronic renal allograft dysfunction
Background: Persistent inflammation and fibrosis have been related to active progression of renal deterioration and reduced survival of kidney transplant. The aim of this study was to determine the impact of single-nucleotide polymorphisms (SNPs) located in regions related to inflammatory and immune processes on the development of chronic renal allograft dysfunction (CRAD). Methods: A retrospective study was carried out on 276 patients who received kidney transplant (KT). SNPs were genotyped via the SNPlex platform. Statistical analysis was performed with SNPstat and regression logistic analyses were adjusted by age and gender of recipients and donors, cold ischemia time and the number of human leukocyte antigen (HLA) mismatches. Results: From 276 patients with KT, 118 were non-CRAD and 158 were CRAD. Three SNPs showed significant associations with CRAD development: rs1800471 in transforming growth factor beta 1 (TGFB1), rs5186 in angiotensin II receptor type 1 (AGTR1), and rs699947 in vascular endothelial growth factor A (VEGFA). GC genotype of rs1800471 was associated with increased odds of CRAD compared to GG genotype (OR=2.65 (95% confidence interval (CI)=1.09; 6.47), p=0.025), as well as AC and AA genotype of rs699947 assuming a dominant model (OR=1.80 (95% CI=1.02; 3.20), p=0.044). Besides, AC and CC genotypes of rs5186 were associated with reduced odds of CRAD assuming a dominant model (OR=0.56 (95% CI=0.33; 0.96), p=0.033). Conclusion: Our findings suggest that three genes related to immunity and inflammation (rs1800471, rs5186 and rs699947) are associated to susceptibility or protection to CRAD, and might have diagnostic utility in predicting the likelihood of developing CRAD.This work was supported by two Grants from Instituto de Salud Carlos III (Ref: PI08/0738 and PI11/00245) and from Junta de Castilla y Le贸n (Ref: GRS 234/A/08). MAJs, AFR and MGF are supported by Grants from Instituto de Salud Carlos III, CM10/00105, UIPY-1377/08 and CM09/00031, respectively.S
Biblioteca virtual redELE
Resumen basado en el de la publicaci贸nT铆tulo del encuentro: 鈥淓xpresi贸n, interacci贸n y mediaci贸n orales en el aula de ELE鈥漇e analiza el concepto de error, su clasificaci贸n, las causas de 茅ste y el concepto de interlengua b谩sico para comprender el proceso de adquisici贸n de una L2 o una LE. Conjunto de actividades pr谩cticas para evitar la aparici贸n de ciertos errores en los aprendientes de espa帽ol.ES