Determining the physical conditions of extremely young Class 0 circumbinary disk around VLA1623A

We present detailed analysis of high-resolution C18O (2-1), SO (88-77), CO (3-2) and DCO+ (3-2) data obtained by the Atacama Large Millimeter/sub-millimeter Array (ALMA) towards a Class 0 Keplerian circumbinary disk around VLA1623A, which represents one of the most complete analysis towards a Class 0 source. From the dendrogram analysis, we identified several accretion flows feeding the circumbinary disk in a highly anisotropic manner. Stream-like SO emission around the circumbinary disk reveals the complicated shocks caused by the interactions between the disk, accretion flows and outflows. A wall-like structure is discovered south of VLA1623B. The discovery of two outflow cavity walls at the same position traveling at different velocities suggests the two outflows from both VLA1623A and VLA1623B overlays on top of each other in the plane of sky. Our detailed flat and flared disk modeling shows that Cycle 2 C18O J = 2-1 data is inconsistent with the combined binary mass of 0.2 Msun as suggested by early Cycle 0 studies. The combined binary mass for VLA1623A should be modified to 0.3 ~ 0.5 Msun.Comment: 26 pages, 20 figures, accepted by ApJ 2020.2.2

Thickness-dependent Dielectric Constant of Few-layer In2Se3 Nano-flakes

The dielectric constant or relative permittivity of a dielectric material, which describes how the net electric field in the medium is reduced with respect to the external field, is a parameter of critical importance for charging and screening in electronic devices. Such a fundamental material property is intimately related to not only the polarizability of individual atoms, but also the specific atomic arrangement in the crystal lattice. In this letter, we present both experimental and theoretical investigations on the dielectric constant of few-layer In2Se3 nano-flakes grown on mica substrates by van der Waals epitaxy. A nondestructive microwave impedance microscope is employed to simultaneously quantify the number of layers and local electrical properties. The measured dielectric constant increases monotonically as a function of the thickness and saturates to the bulk value at around 6 ~ 8 quintuple layers. The same trend of layer-dependent dielectric constant is also revealed by first-principle calculations. Our results of the dielectric response, being ubiquitously applicable to layered 2D semiconductors, are expected to be significant for this vibrant research field.Comment: 15 pages, 4 figures, 1 table in Nano letters, 2015 ASA

Dimension-six CP-conserving operators of the third-family quarks and their effects on collider observables

We list all possible dimension-six CP-conserving $SU_c(3)\times SU_L(2) \times U_Y(1)$ invariant operators involving the third-family quarks which could be generated by new physics at a higher scale. Expressions for these operators after electroweak gauge symmetry breaking and the induced effective couplings $Wt\bar b$, $Xb\bar b$ and $Xt\bar t$ $( X=Z,\gamma,g,H)$ are presented. Analytic expressions for the tree level contributions of all these operators to the observables $R_b$ and $A^b_{FB}$ at LEP I, $\sigma(e^+e^-\rightarrow b\bar b)$ and $A^b_{FB}$ at LEP II, $\sigma(e^+e^-\rightarrow t\bar t)$ and $A_{FB}^t$ at the NLC, as well as $\sigma(p\bar p\rightarrow t\bar b+X)$ at the Tevatron upgrade, are provided. The effects of these operators on different electroweak observables are discussed and numerical examples presented. Numerical analyses show that in the coupling region allowed by $R_b$ and $A^b_{FB}$ at LEP I, some of the new physics operators can still have significant contributions at LEP II, the Tevatron and the NLC.Comment: 25 page

Postoperative hyperphosphatemia significantly associates with adverse survival in colorectal cancer patients

BACKGROUND: Hyperphosphatemia has been implicated in the development and treatment of various cancers. However, whether it can be used as a direct prognostic marker of colorectal cancer (CRC) has remained unexplored. Given new insights into the importance of hyperphosphatemia in CRC, we sought to evaluate the association of hyperphosphatemia with the clinical outcomes of this disease. METHODS: In a retrospective analysis of a well-characterized clinic-based cohort with 1,241 CRC patients, we assessed the association of postoperative hyperphosphatemia with patient overall survival. RESULTS: Postoperative hyperphosphatemia measured within the first month after surgery was significantly associated with CRC survival. Compared to patients with a normal phosphate level, those with hyperphosphatemia exhibited a significant unfavorable overall survival with a hazard ratio (HR) of 1.84 (95% confidence interval [CI] 1.49–2.29, P=2.6×10(−8), (log-rank P=1.2×10(−7)). Stratified analyses indicated the association was more pronounced in patients with colon (HR=2.00, 95% CI 1.57–2.56, P=3.17×10(−8)) but not rectal cancer (HR=0.96, 95% CI 0.58–1.59, P=0.889) (P interaction=0.023), as well as in those not receiving chemotherapy (HR=2.15, 95% CI 1.59–2.90, P=6.2×10(−7)) but not in those receiving chemotherapy (HR=1.30, 95% CI 0.92–1.82, P=0.136) (P interaction=0.012). Flexible parametric survival model demonstrated that the increased risk for death conferred by postoperative hyperphosphatemia persisted over 150 months after surgery. CONCLUSION: Our data indicated that postoperative hyperphosphatemia might be used as a prognostic marker of CRC patients after surgery. Since phosphate level is routinely tested in clinics, it may be incorporated into clinical models to predict CRC survival

Genotoxic Klebsiella pneumoniae in Taiwan

Colibactin is a nonribosomal peptide-polyketide synthesized by multi-enzyme complexes encoded by the pks gene cluster. Colibactin-producing Escherichia coli have been demonstrated to induce host DNA damage and promote colorectal cancer (CRC) development. In Taiwan, the occurrence of pyogenic liver abscess (PLA) has been suggested to correlate with an increasing risk of CRC, and Klebsiella pneumoniae is the predominant PLA pathogen in Taiwan

Efficient learning of tt-doped stabilizer states with single-copy measurements

One of the primary objectives in the field of quantum state learning is to develop algorithms that are time-efficient for learning states generated from quantum circuits. Earlier investigations have demonstrated time-efficient algorithms for states generated from Clifford circuits with at most $\log(n)$ non-Clifford gates. However, these algorithms necessitate multi-copy measurements, posing implementation challenges in the near term due to the requisite quantum memory. On the contrary, using solely single-qubit measurements in the computational basis is insufficient in learning even the output distribution of a Clifford circuit with one additional $T$ gate under reasonable post-quantum cryptographic assumptions. In this work, we introduce an efficient quantum algorithm that employs only nonadaptive single-copy measurement to learn states produced by Clifford circuits with a maximum of $O(\log n)$ non-Clifford gates, filling a gap between the previous positive and negative results.Comment: 6 page

Automatic age estimation system for face images

Humans are the most important tracking objects in surveillance systems. However, human tracking is not enough to provide the required information for personalized recognition. In this paper, we present a novel and reliable framework for automatic age estimation based on computer vision. It exploits global face features based on the combination of Gabor wavelets and orthogonal locality preserving projections. In addition, the proposed system can extract face aging features automatically in real-time. This means that the proposed system has more potential in applications compared to other semi-automatic systems. The results obtained from this novel approach could provide clearer insight for operators in the field of age estimation to develop real-world applications. © 2012 Lin et al