997 research outputs found

    Work-Life Balance: Perceived Differences of Teleworkers and Non-Teleworkers

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    As the growth in the number of dual-career couples continues, couples attempt to balance the demands of career and family (Berlato & CorrĂȘa, 2017). A healthy work environment potentially supports a positive work-life balance for employees. Supportive work environments increase morale, job satisfaction, job retention, productivity, as well as a fulfilling family life (Molla, 2015). Failure to assist employees with finding work-life balance risk the loss of a positive work environment for a company’s employees and the entire organization. Therefore, this human capital study seeks to build on the current research surrounding assisting organizations to find work-life balance for their telework employees. This study surveyed teleworkers and non-teleworkers to compare perceived differences of work-family conflict, family-work conflict, and role overload. Supported by Emery and Trist’s (1969) Sociotechnical Systems Theory, and DeSanctis and Poole’s (1994) Adaptive Structuration theory, this study sought to determine differences between telework and work-life balance. Using an ANOVA to compare the teleworkers and non-teleworkers, the study analyzes the participants’ (N = 68) answers of the Work-Family Interface Scale. The study did not find a statistically significant difference between teleworkers and non-teleworkers’ work-life balance. Recommendations include conducting this study with a larger population and using additional demographic data as independent variables

    La question du standard : entre mono/unilinguisme, pluricentrisme et polynomie

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    It is hard to conceive languages without standard. Then it must be defined and elaborated within sociolinguistic patterns and linguistic ideologies. These processes will be considered in the case of established vehicular languages and minorized languages, according to a single (i.e. monolingualism and unilingualism) or plural (i.e. pluricentric and polynomic) normative prescription centre. The latter two apply, the one for a compositional model, the other without any standard. This paper tries to demonstrate how these options have been growing and revolve around intralinguistic and interlinguistic “travelling”, according to the way suggested by Corsican sociolinguist Marcellesi for his own language, and appropriate set limits using it.On ne conçoit pas de langue sans standard. Encore faut-il le dĂ©finir et l’élaborer, selon les configurations sociolinguistiques et les idĂ©ologies linguistiques. On envisagera ces processus dans le cas des grandes langues Ă©tablies puis des langues minorĂ©es, selon le questionnement existant entre centre de prescription unique (mono et unilinguisme) et pluriel (pluricentrisme et polynomie). Ces derniers postulent, l’un un modĂšle compositionnel, l’autre, l’absence de standard. On montrera comment ces deux notions ont prospĂ©rĂ© et trouvent Ă  s’articuler Ă  travers le « jeu Â» intra et interlinguistique suggĂ©rĂ© par le sociolinguiste corse J.-B. Marcellesi pour sa langue, et enfin quelles sont les limitations qu’il prĂ©sente

    La Catalogne et les Communautés Autonomes espagnoles : un modÚle pour les « langues de France » ?

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    Les « langues rĂ©gionales » sont devenues « langues de France » grĂące au volontarisme de Bernard Cerquiglini, qui a impulsĂ© du sommet de l’État, au pays de l’unilinguisme (mais sans grands moyens il est vrai), une vĂ©ritable politique linguistique prenant en compte la « diversité ». On vise ici Ă  rendre compte de cette Ă©volution en Ă©tablissant un parallĂšle avec les politiques menĂ©es dans le cadre de l’Espagne des Autonomies, et singuliĂšrement de la Catalogne

    Guest displacement in silicon clathrates

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    We study both theoretically and experimentally the structure of the doped silicon clathrate II NaxSi34. We find that contrary to published works, the sodium atoms do not retain the T-d symmetry inside the Si-28 cages and move about 1 A away from the center of the cage. This displacement, in conjunction with that of a sodium atom in an adjacent Si-28 cage, leads to a "dimerization" of sodium atoms. As a consequence, Rietveld refinements of x-ray diffraction spectra and transport, vibrational, and electronic properties must be revisited

    Crystal structure of a novel type of odorant binding protein from Anopheles gambiae, belonging to the C+ class

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    International audienceAnopheles gambiae (Agam) relies on its olfactory system to target human prey, leading eventually to injection of Plasmodium falciparum, the malaria vector. Odorant-binding proteins (OBPs) are the first line of proteins involved in odorant recognition. They interact with olfactory receptors and thus constitute an interesting target for insect control. We undertook a large-scale study of proteins belonging to the olfactory system of Agam with the aim of preventing insect bites by designing strong olfactory repellents. We determined the 3D structures of several Agam OBPs alone or in complex with model compounds. Here, we report the first 3D structure of a member of the OBP C+ class, AgamOBP47, which has a longer sequence than classical OBPs and contains 6 disulphide bridges. AgamOBP47 possesses a core of six a-helices and three disulphide bridges, similar to the classical OBP fold. Two extra loops and the N- and C-terminal extra segments contain two additional a-helices and are maintained together by three disulphide bridges. They are embrace the classical OBP core domain. The binding site of OBP47 is located between the core and the additional domains. Two crevices are observed on opposite sides of OBP47, which are joined together by a shallow channel of sufficient size to accommodate a model of the best tested ligand. The binding sites of C+ class OBPs exhibit therefore different characteristics of their binding site, as compared to classical OBPs, which should leave to markedly diverse functional implications

    Protein kinase C inhibitors stimulate arachidonic and docosahexaenoic acids release from uterine stromal cells through a Ca2+-independent pathway1Enzymes: Phospholipase A2 (EC 3.1.1.4).1

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    AbstractThe mechanisms underlying arachidonic acid (AA) release by uterine stromal (UIII) cells were studied. Stimulation of AA release by calcium ionophore and PMA are inhibited by various PKC inhibitors and by calcium deprivation. These results suggest the involvement of an AA-specific cPLA2 as the release of docosahexaenoic acid (DHA) from prelabelled cells is much lower than the release of AA. The results also show a more original stimulation of AA and DHA release induced by PKC inhibitors, which is insensitive to calcium deprivation. This stimulation is not due to acyltransferase inhibition, suggesting the participation of a Ca2+-independent PLA2 (iPLA2). However, iPLA2 activity measured in UIII cells is inhibited by the specific iPLA2 inhibitor, BEL, and is not stimulated by PKC inhibitors, in contrast with the AA and DHA release. It seems therefore that this iPLA2 cannot be involved in this mechanism. The participation of another iPLA2, BEL-insensitive, is discussed

    Commercial Logging and HIV Epidemic, Rural Equatorial Africa

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    We found a high seroprevalence of HIV among young women in a commercial logging area in Cameroon. The vulnerability of these young women could be related to commercial logging and the social and economic networks it induces. The environmental changes related to this industry in Equatorial Africa may facilitate HIV dissemination

    Intraoperative Music to Promote Patient Outcome (IMPROMPTU):A Double-Blind Randomized Controlled Trial

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    Introduction: Perioperative music can have beneficial effects on postoperative pain, anxiety, opioid requirement, and the physiological stress response to surgery. The aim was to assess the effects of intraoperative music during general anesthesia in patients undergoing surgery for esophagogastric cancer. Materials and methods: The IMPROMPTU study was a double-blind, placebo-controlled, randomized multicenter trial. Adult patients undergoing surgery for stage II-III esophagogastric cancer were eligible. Exclusion criteria were a hearing impairment, insufficient Dutch language knowledge, corticosteroids use, or objection to hearing unknown music. Patients wore active noise-cancelling headphones intraoperatively with preselected instrumental classical music (intervention) or no music (control). Computerized randomization with centralized allocation, stratified according to surgical procedure using variable block sizes, was employed. Primary endpoint was postoperative pain on the first postoperative day. Secondary endpoints were postoperative pain during the first postoperative week, postoperative opioid requirement, intraoperative medication requirement, the stress response to surgery, postoperative complication rate, length of stay, and mortality, with follow-up lasting 30 d. Results: From November 2018 to September 2020, 145 patients were assessed and 83 randomized. Seventy patients (music n = 31, control n = 39) were analyzed. Median age was 70 [IQR 63–70], and 48 patients (69%) were male. Music did not reduce postoperative pain (numeric rating scale 1.8 (SD0.94) versus 2.0 (1.0), mean difference −0.28 [95% CI -0.76–0.19], P = 0.236). No statistically significant differences were seen in medication requirement, stress response, complication rate, or length of stay. Conclusions: Intraoperative, preselected, classical music during esophagogastric cancer surgery did not significantly improve postoperative outcome and recovery when compared to no music using noise-cancelling headphones.</p

    Intraoperative Music to Promote Patient Outcome (IMPROMPTU):A Double-Blind Randomized Controlled Trial

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    Introduction: Perioperative music can have beneficial effects on postoperative pain, anxiety, opioid requirement, and the physiological stress response to surgery. The aim was to assess the effects of intraoperative music during general anesthesia in patients undergoing surgery for esophagogastric cancer. Materials and methods: The IMPROMPTU study was a double-blind, placebo-controlled, randomized multicenter trial. Adult patients undergoing surgery for stage II-III esophagogastric cancer were eligible. Exclusion criteria were a hearing impairment, insufficient Dutch language knowledge, corticosteroids use, or objection to hearing unknown music. Patients wore active noise-cancelling headphones intraoperatively with preselected instrumental classical music (intervention) or no music (control). Computerized randomization with centralized allocation, stratified according to surgical procedure using variable block sizes, was employed. Primary endpoint was postoperative pain on the first postoperative day. Secondary endpoints were postoperative pain during the first postoperative week, postoperative opioid requirement, intraoperative medication requirement, the stress response to surgery, postoperative complication rate, length of stay, and mortality, with follow-up lasting 30 d. Results: From November 2018 to September 2020, 145 patients were assessed and 83 randomized. Seventy patients (music n = 31, control n = 39) were analyzed. Median age was 70 [IQR 63–70], and 48 patients (69%) were male. Music did not reduce postoperative pain (numeric rating scale 1.8 (SD0.94) versus 2.0 (1.0), mean difference −0.28 [95% CI -0.76–0.19], P = 0.236). No statistically significant differences were seen in medication requirement, stress response, complication rate, or length of stay. Conclusions: Intraoperative, preselected, classical music during esophagogastric cancer surgery did not significantly improve postoperative outcome and recovery when compared to no music using noise-cancelling headphones.</p
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