3,755 research outputs found
Carrier and polarization dynamics in monolayer MoS2
In monolayer MoS2 optical transitions across the direct bandgap are governed
by chiral selection rules, allowing optical valley initialization. In time
resolved photoluminescence (PL) experiments we find that both the polarization
and emission dynamics do not change from 4K to 300K within our time resolution.
We measure a high polarization and show that under pulsed excitation the
emission polarization significantly decreases with increasing laser power. We
find a fast exciton emission decay time on the order of 4ps. The absence of a
clear PL polarization decay within our time resolution suggests that the
initially injected polarization dominates the steady state PL polarization. The
observed decrease of the initial polarization with increasing pump photon
energy hints at a possible ultrafast intervalley relaxation beyond the
experimental ps time resolution. By compensating the temperature induced change
in bandgap energy with the excitation laser energy an emission polarization of
40% is recovered at 300K, close to the maximum emission polarization for this
sample at 4K.Comment: 7 pages, 7 figures including supplementary materia
Abolishing user fees for children and pregnant women trebled uptake of malaria-related interventions in Kangaba, Mali.
Malaria is the most common cause of morbidity and mortality in children under 5 in Mali. Health centres provide primary care, including malaria treatment, under a system of cost recovery. In 2005, Médecins sans Frontieres (MSF) started supporting health centres in Kangaba with the provision of rapid malaria diagnostic tests and artemisinin-based combination therapy. Initially MSF subsidized malaria tests and drugs to reduce the overall cost for patients. In a second phase, MSF abolished fees for all children under 5 irrespective of their illness and for pregnant women with fever. This second phase was associated with a trebling of both primary health care utilization and malaria treatment coverage for these groups. MSF's experience in Mali suggests that removing user fees for vulnerable groups significantly improves utilization and coverage of essential health services, including for malaria interventions. This effect is far more marked than simply subsidizing or providing malaria drugs and diagnostic tests free of charge. Following the free care strategy, utilization of services increased significantly and under-5 mortality was reduced. Fee removal also allowed for more efficient use of existing resources, reducing average cost per patient treated. These results are particularly relevant for the context of Mali and other countries with ambitious malaria treatment coverage objectives, in accordance with the United Nations Millennium Development Goals. This article questions the effectiveness of the current national policy, and the effectiveness of reducing the cost of drugs only (i.e. partial subsidies) or providing malaria tests and drugs free for under-5s, without abolishing other related fees. National and international budgets, in particular those that target health systems strengthening, could be used to complement existing subsidies and be directed towards effective abolition of user fees. This would contribute to increasing the impact of interventions on population health and, in turn, the effectiveness of aid
Perception and prediction of simple object interactions
For humans, it is useful to be able to visually detect an object's physical properties. One potentially important source of information is the way the object moves and interacts with other objects in the environment. Here, we use computer simulations of a virtual ball bouncing on a horizontal plane to study the correspondence between our ability to estimate the ball's elasticity and to predict its future path. Three experiments were conducted to address (1) perception of the ball's elasticity, (2) interaction with the ball, and (3) prediction of its trajectory. The results suggest that different strategies and information sources are used for passive perception versus actively predicting future behavior
AMBER/VLTI high spectral resolution observations of the Br emitting region in HD 98922. A compact disc wind launched from the inner disc region
We analyse the main physical parameters and the circumstellar environment of
the young Herbig Be star HD 98922. We present AMBER/VLTI high spectral
resolution (R =12000) interferometric observations across the Br line,
accompanied by UVES high-resolution spectroscopy and SINFONI-AO assisted
near-infrared integral field spectroscopic data. To interpret our observations,
we develop a magneto-centrifugally driven disc-wind model. Our analysis of the
UVES spectrum shows that HD 98922 is a young (~5x10^5 yr) Herbig Be star
(SpT=B9V), located at a distance of 440(+60-50) pc, with a mass accretion rate
of ~9+/-3x10^(-7) M_sun yr^(-1). SINFONI K-band AO-assisted imaging shows a
spatially resolved circumstellar disc-like region (~140 AU in diameter) with
asymmetric brightness distribution. Our AMBER/VLTI UT observations indicate
that the Br emitting region (radius ~0.31+/-0.04 AU) is smaller than
the continuum emitting region (inner dust radius ~0.7+/-0.2 AU), showing
significant non-zero V-shaped differential phases (i.e. non S-shaped, as
expected for a rotating disc). The value of the continuum-corrected pure
Br line visibility at the longest baseline (89 m) is ~0.8+/-0.1, i.e.
the Br emitting region is partially resolved. Our modelling suggests
that the observed Br line-emitting region mainly originates from a disc
wind with a half opening angle of 30deg, and with a mass-loss rate of ~2x10(-7)
M_sun yr^(-1). The observed V-shaped differential phases are reliably
reproduced by combining a simple asymmetric continuum disc model with our
Br disc-wind model. The Br emission of HD 98922 can be modelled
with a disc wind that is able to approximately reproduce all interferometric
observations if we assume that the intensity distribution of the dust continuum
disc is asymmetric.Comment: Accepted for publication on Astronomy \& Astrophysics. High
resolution figures published on the main journal (see Astronomy &
Astrophysics: Forthcoming) or at
www.researchgate.net/profile/Alessio_Caratti_o_Garatti/publication
Selective ablation of pillar and deiters' cells severely affects cochlear postnatal development and hearing in mice.
Mammalian auditory hair cells (HCs) are inserted into a well structured environment of supporting cells (SCs) and acellular matrices. It has been proposed that when HCs are irreversibly damaged by noise or ototoxic drugs, surrounding SCs seal the epithelial surface and likely extend the survival of auditory neurons. Because SCs are more resistant to damage than HCs, the effects of primary SC loss on HC survival and hearing have received little attention. We used the Cre/loxP system in mice to specifically ablate pillar cells (PCs) and Deiters' cells (DCs). In Prox1CreER(T2)+/-;Rosa26(DTA/+) (Prox1DTA) mice, Cre-estrogen receptor (CreER) expression is driven by the endogenous Prox1 promoter and, in presence of tamoxifen, removes a stop codon in the Rosa26(DTA/+) allele and induces diphtheria toxin fragment A (DTA) expression. DTA produces cell-autonomous apoptosis. Prox1DTA mice injected with tamoxifen at postnatal days 0 (P0) and P1 show significant DC and outer PC loss at P2-P4, that reaches ∼70% by 1 month. Outer HC loss follows at P14 and is almost complete at 1 month, while inner HCs remain intact. Neural innervation to the outer HCs is disrupted in Prox1DTA mice and auditory brainstem response thresholds in adults are 40-50 dB higher than in controls. The hearing deficit correlates with loss of cochlear amplification. Remarkably, in Prox1DTA mice, the auditory epithelium preserves the ability to seal the reticular lamina and spiral ganglion neuron counts are normal, a key requirement for cochlear implant success. In addition, our results show that cochlear SC pools should be appropriately replenished during HC regeneration strategies
Spin-dependent electron dynamics and recombination in GaAs(1-x)N(x) alloys at room temperature
We report on both experimental and theoretical study of conduction-electron
spin polarization dynamics achieved by pulsed optical pumping at room
temperature in GaAs(1-x)N(x) alloys with a small nitrogen content (x = 2.1,
2.7, 3.4%). It is found that the photoluminescence circular polarization
determined by the mean spin of free electrons reaches 40-45% and this giant
value persists within 2 ns. Simultaneously, the total free-electron spin decays
rapidly with the characteristic time ~150 ps. The results are explained by
spin-dependent capture of free conduction electrons on deep paramagnetic
centers resulting in dynamical polarization of bound electrons. We have
developed a nonlinear theory of spin dynamics in the coupled system of
spin-polarized free and localized carriers which describes the experimental
dependencies, in particular, electron spin quantum beats observed in a
transverse magnetic field.Comment: 5 pages, 4 figures, Submitted to JETP Letter
The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.
BACKGROUND: Despite recent decreases in HIV incidence in many sub-Saharan African countries, there is little evidence that specific behavioural interventions have led to a reduction in HIV among young people. Further and wider-scale decreases in HIV require better understanding of when behaviour change occurs and why. The MEMA kwa Vijana adolescent sexual and reproductive health intervention has been implemented in rural Mwanza, Tanzania since 1999. A long-term evaluation in 2007/8 found that the intervention improved knowledge, attitudes to sex and some reported risk behaviours, but not HIV or HSV2 prevalence. The aim of this paper was to assess the differential impact of the intervention according to gender, age, marital status, number of years of exposure and time since last exposure to the intervention. METHODS: In 2007, a cross-sectional survey was conducted in the 20 trial communities among 13,814 young people (15-30 yrs) who had attended intervention or comparison schools between 1999 and 2002. Outcomes for which the intervention had an impact in 2001 or 2007 were included in this subgroup analysis. Data were analysed using cluster-level methods for stratified cluster-randomised trials, using interaction tests to determine if intervention impact differed by subgroup. RESULTS: Taking into account multiplicity of testing, concurrence with a priori hypotheses and consistency within the results no strong effect-modifiers emerged. Impact on pregnancy knowledge and reported attitudes to sex increased with years of exposure to high-quality intervention. CONCLUSIONS: The desirable long-term impact of the MEMA kwa Vijana intervention did not vary greatly according to the subgroups examined. This suggests that the intervention can have an impact on a broad cross-section of young people in rural Mwanza. TRIAL REGISTRATION: ClinicalTrials.gov NCT00248469
Barking up the Wrong Evidence Tree. Comment on Lurie & Rosenthal, “Concurrent Partnerships as a Driver of the HIV Epidemic in Sub-Saharan Africa? The Evidence is Limited”
The Magnetic Fields at the Surface of Active Single G-K Giants
We investigate the magnetic field at the surface of 48 red giants selected as
promising for detection of Stokes V Zeeman signatures in their spectral lines.
We use the spectropolarimeters Narval and ESPaDOnS to detect circular
polarization within the photospheric absorption lines of our targets and use
the least-squares deconvolution (LSD) method. We also measure the classical
S-index activity indicator, and the stellar radial velocity. To infer the
evolutionary status of our giants and to interpret our results, we use
state-of-the-art stellar evolutionary models with predictions of convective
turnover times. We unambiguously detect magnetic fields via Zeeman signatures
in 29 of the 48 red giants in our sample. Zeeman signatures are found in all
but one of the 24 red giants exhibiting signs of activity, as well as 6 out of
17 bright giant stars.The majority of the magnetically detected giants are
either in the first dredge up phase or at the beginning of core He burning,
i.e. phases when the convective turnover time is at a maximum: this corresponds
to a 'magnetic strip' for red giants in the Hertzsprung-Russell diagram. A
close study of the 16 giants with known rotational periods shows that the
measured magnetic field strength is tightly correlated with the rotational
properties, namely to the rotational period and to the Rossby number Ro. Our
results show that the magnetic fields of these giants are produced by a dynamo.
Four stars for which the magnetic field is measured to be outstandingly strong
with respect to that expected from the rotational period/magnetic field
relation or their evolutionary status are interpreted as being probable
descendants of magnetic Ap stars. In addition to the weak-field giant Pollux, 4
bright giants (Aldebaran, Alphard, Arcturus, eta Psc) are detected with
magnetic field strength at the sub-gauss level.Comment: 34 pages, 22 Figures, accepted for publication in Astronomy &
Astrophysic
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