245 research outputs found

    Executing Whiteness: Fictional and Nonfictional Accounts of Capital Punishment in the United States, 1915-1940

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    Over the course of the nineteenth century, elites in the United States increasingly sought to privatize executions and rationalize execution protocols. The source of this change is well known to historians of punishment: a fear that public executions had become unwieldy spectacles drove state actors to move these events into jail yards, at first, and then, with the advent of new technologies, into the interior of centralized prisons that were often far from the county in which the crime had occurred. The centralization of executions and the rationalization of execution protocols reflected and reinforced a more bureaucratic image of the state as an abstract entity run by professionals operating in rule-bound roles rather than particular actors governing in an unsystematic way. After this period of change, the aesthetics of the execution ceremony had so thoroughly changed that abolitionist critics were beginning, by the late 1950s, to cite their hyper-rationality as evidence of their inhumanity. But if changes to the modes, protocols, and settings of state killing seemed to diminish the recognition of human dignity in the nation’s execution chambers, they were countered by the existence and, with the birth of film, the expansion of popular renderings of the death penalty aimed at preserving the sacredness of the execution ceremony. Fictional and nonfictional execution stories, disproportionately centered around the execution of white men, offered evidence to those who did not have direct access to executions that modernity had not fully captured the soul of punishment. In newspapers, on stage, and on screen, accounts of condemned men surrounded the institution of capital punishment with a melodramatic buffer that maintained executions as events in which the humanity of the state that killed and the condemned who died was constantly foregrounded, even as execution modes and protocols themselves became rationalized and machine-like

    Vegetation dynamics on an abandoned vacuum-mined peatland: 5 years of monitoring.

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    Abstract We studied from 1998 to 2002 the fine-scale vegetation dynamics of a poorly regenerated vacuum-mined bog located in southern Quebec. We selected mined sites that have been abandoned for 14 years and monitored the vascular and non-vascular plants, and some hydrological characteristics. We focussed our study on the monitoring of cotton-grass (Eriophorum vaginatum L.) tussocks. Major changes in the plant cover were observed during the five-year period, such as a decrease (26-31%) in the number of cotton-grass tussocks and an increase in the ericaceous shrub cover. The water table level (lower than 40 cm below the soil surface) and frost heaving appear to be the main factors explaining the failure of cotton-grass and of other typical bog plant species to colonize abandoned mined surfaces. The ericaceous shrub cover, although increasing, was still sparse even after two decades of abandonment, and it may take several additional decades before a complete shrub cover establishes itself. While the natural revegetation process of this vacuum-mined bog is still dynamic after two decades of abandonment, there is no evidence to suggest that vegetation assemblages will eventually resemble those of undisturbed peatlands

    Transcriptional approach to study porcine tracheal epithelial cells individually or dually infected with swine influenza virus and Streptococcus suis

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    Background: Swine influenza is a highly contagious viral infection in pigs affecting the respiratory tract that can have significant economic impacts. Streptococcus suis serotype 2 is one of the most important post-weaning bacterial pathogens in swine causing different infections, including pneumonia. Both pathogens are important contributors to the porcine respiratory disease complex. Outbreaks of swine influenza virus with a significant level of co-infections due to S. suis have lately been reported. In order to analyze, for the first time, the transcriptional host response of swine tracheal epithelial (NPTr) cells to H1N1 swine influenza virus (swH1N1) infection, S. suis serotype 2 infection and a dual infection, we carried out a comprehensive gene expression profiling using a microarray approach. Results: Gene clustering showed that the swH1N1 and swH1N1/S. suis infections modified the expression of genes in a similar manner. Additionally, infection of NPTr cells by S. suis alone resulted in fewer differentially expressed genes compared to mock-infected cells. However, some important genes coding for inflammatory mediators such as chemokines, interleukins, cell adhesion molecules, and eicosanoids were significantly upregulated in the presence of both pathogens compared to infection with each pathogen individually. This synergy may be the consequence, at least in part, of an increased bacterial adhesion/invasion of epithelial cells previously infected by swH1N1, as recently reported. Conclusion: Influenza virus would replicate in the respiratory epithelium and induce an inflammatory infiltrate comprised of mononuclear cells and neutrophils. In a co-infection situation, although these cells would be unable to phagocyte and kill S. suis, they are highly activated by this pathogen. S. suis is not considered a primary pulmonary pathogen, but an exacerbated production of proinflammatory mediators during a co-infection with influenza virus may be important in the pathogenesis and clinical outcome of S. suis-induced respiratory diseases

    Frequency of false-positive FISH 1p/19q codeletion in adult diffuse astrocytic gliomas

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    Oligodendroglioma is genetically defined by concomitant IDH (IDH1/IDH2) mutation and whole-arm 1p/19q codeletion. Codeletion of 1p/19q traditionally evaluated by fluorescence in situ hybridization (FISH) cannot distinguish partial from whole-arm 1p/19q codeletion. Partial 1p/19q codeletion called positive by FISH is diagnostically a "false-positive" result. Chromosomal microarray (CMA) discriminates partial from whole-arm 1p/19q codeletion. Herein, we aimed to estimate the frequency of partial 1p/19q codeletion that would lead to a false-positive FISH result

    Spinal intradural extraosseous Ewing's sarcoma

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    Extraosseous Ewing's sarcoma (EES) involving the central nervous system is rare, but can be diagnosed and distinguished from other primitive neuroectodermal tumors (PNET) by identification of the chromosomal translocation (11;22)(q24;q12). We report EES arising from the spinal intradural extramedullary space, based on imaging, histopathological, and molecular data in two men, ages 50 and 60 years old and a review of the literature using PubMed (1970–2009). Reverse transcriptase polymerase chain reaction (RT-PCR) identified the fusion product FL1-EWS. Multimodal therapy, including radiation and alternating chemotherapy including vincristine, cyclophosphamide, doxorubicin and ifosfamide and etoposide led to local tumor control and an initial, favorable therapeutic response. No systemic involvement was seen from the time of diagnosis to the time of last follow-up (26 months) or death (4 years). This report confirms that EES is not confined to the earliest decades of life, and like its rare occurrence as an extra-axial meningeal based mass intracranially, can occasionally present as an intradural mass in the spinal canal without evidence of systemic tumor. Gross total resection followed by multimodal therapy may provide for extended progression free and overall survival
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