4,850 research outputs found
A Project Portfolio Management model adapted to non-profit organizations
As they strive towards greater professionalism in carrying out their activities, non-profit organizations (NPOs) have begun paying attention to project management. The non-profit sector (NPS) has also begun to adopt strategic planning techniques, thus making the acceptance of project portfolio management (PPM) methodology a natural consequence. This article aims to propose a project portfolio management model adapted to the context of NPOs
Detection of Contact Binaries Using Sparse High Phase Angle Lightcurves
We show that candidate contact binary asteroids can be efficiently identified
from sparsely sampled photometry taken at phase angles >60deg. At high phase
angle, close/contact binary systems produce distinctive lightcurves that spend
most of the time at maximum or minimum (typically >1mag apart) brightness with
relatively fast transitions between the two. This means that a few (~5) sparse
observations will suffice to measure the large range of variation and identify
candidate contact binary systems. This finding can be used in the context of
all-sky surveys to constrain the fraction of contact binary near-Earth objects.
High phase angle lightcurve data can also reveal the absolute sense of the
spin.Comment: 4 pages, 4 figures, 1 table. Accepted for publication in ApJ
The formation of the solar system
The solar system started to form about 4.56 Gyr ago and despite the long
intervening time span, there still exist several clues about its formation. The
three major sources for this information are meteorites, the present solar
system structure and the planet-forming systems around young stars. In this
introduction we give an overview of the current understanding of the solar
system formation from all these different research fields. This includes the
question of the lifetime of the solar protoplanetary disc, the different stages
of planet formation, their duration, and their relative importance. We consider
whether meteorite evidence and observations of protoplanetary discs point in
the same direction. This will tell us whether our solar system had a typical
formation history or an exceptional one. There are also many indications that
the solar system formed as part of a star cluster. Here we examine the types of
cluster the Sun could have formed in, especially whether its stellar density
was at any stage high enough to influence the properties of today's solar
system. The likelihood of identifying siblings of the Sun is discussed.
Finally, the possible dynamical evolution of the solar system since its
formation and its future are considered.Comment: 36 pages, 7 figures, invited review in Physica Script
Transplante autólogo de células estaminais em leucemiamielóide aguda: factores com Influência na sobrevida: experiência de 13 anos de uma Instituição
© Ordem dos MédicosWe report our results of autologous stem cell transplantation (SCT) in patients with AML during the last 13 years. Between August 1990 and December 2003, 42 patients with acute myeloid leukemia (AML) received an autologous SCT. Patients were classified as standard risk if first complete remission (CR) was induced after one or two chemotherapy regimens and the white blood cell count at presentation was below 50,000/mL (n=12), while patients requiring more than two induction regimens to attain first CR and with CR2 ou more advanced disease and/or had a higher white blood cell count at presentation were defined as high risk (n=30). Twenty one patients were transplanted in first CR. The median patient age was 24 years (range, 2-56 years), and the median time interval from diagnosis to autologous SCT was 9 months (range 3-87 months). The conditioning regimen for SCT consisted of busulfan (BU) 16 mg/kg and melfalan (MEL) 180 mg/m2 (BUMEL) in 17 (40%) patients and busulfan 16 mg/kg and VP-16 60 mg/kg (BUVP16) in 22 (52%) patients. Three patients received a different conditioning regimen with BCNU 300 mg/m2, VP16 2 g/m2 and melphalan 160 mg/m2 (BEM). Twenty five (60%) patients received bone marrow (BM), 11 (26%) patients received peripheral blood stem cells (PBSC) and 6 patients (14%) received BM plus PBSC. With a median follow-up of 7 years, the 13 year overall survival (OS) and diseasefree survival (DFS) of all patients is 52% and 40%, respectively. In univariate analysis, males had a significantly superior DFS than females (55% vs 22%, p=0.003), and patients younger than 15 years of age had significantly superior OS and DFS than older patients (50% vs 35%, p=0.05; and 50% vs 28%, p=0.03, respectively). Patients with FAB M3 subtype also had a superior OS than the other FAB subtypes (100% vs 44%, p=0.05). There was a strong statistical correlation between risk group and survival. In fact, the patients with standard risk had a superior OS and DFS than those with high risk disease (67% vs 23%, p=0.0004; and 50% vs 27%, p=0.01, respectively). When patients with FAB M3 disease were excluded from the analysis, the group with standard risk continue to have a superior OS and DFS (67% vs 13%, p=0.008; and 50% vs 14%, p=0.02, respectively). We conclude that autologous SCT is an effective treatment in AML with the possibility of long survivorship, particularly in patients with standard risk disease.info:eu-repo/semantics/publishedVersio
Quantum critical 5f-electrons avoid singularities in U(Ru,Rh)2Si2
We present specific heat measurements of 4% Rh-doped U(Ru,Rh)2Si2 at magnetic
fields above the proposed metamagnetic transition field Hm~34 T, revealing
striking similarities to the isotructural Ce analog CeRu2Si2, suggesting that
strongly renormalized hybridized band models apply equally well to both
systems. The vanishing bandwidths as H --> Hm are consistent with a putative
quantum critical point close to Hm. The existence of a phase transition into an
ordered phase in the vicinity of Hm for 4% Rh-doped U(Ru,Rh)2Si2, but not for
CeRu2Si2, is consistent with a stronger super-exchange in the case of the U 5-f
system, with irreversible processes at the transition revealing a strong
coupling of the 5f orbitals to the lattice, most suggestive of orbital or
electric quadrupolar order.Comment: 4 pages, 4 figure
Near-infrared spatially resolved spectroscopy of (136108) Haumea's multiple system
The transneptunian region of the solar system is populated by a wide variety
of icy bodies showing great diversity. The dwarf planet (136108) Haumea is
among the largest TNOs and displays a highly elongated shape and hosts two
moons, covered with crystalline water ice like Hamuea. Haumea is also the
largest member of the sole TNO family known to date. A catastrophic collision
is likely responsible for its unique characteristics. We report here on the
analysis of a new set of observations of Haumea obtained with SINFONI at the
ESO VLT. Combined with previous data, and using light-curve measurements in the
optical and far infrared, we carry out a rotationally resolved spectroscopic
study of the surface of Haumea. We describe the physical characteristics of the
crystalline water ice present on the surface of Haumea for both regions, in and
out of the Dark Red Spot (DRS), and analyze the differences obtained for each
individual spectrum. The presence of crystalline water ice is confirmed over
more than half of the surface of Haumea. Our measurements of the average
spectral slope confirm the redder characteristic of the spot region. Detailed
analysis of the crystalline water-ice absorption bands do not show significant
differences between the DRS and the remaining part of the surface. We also
present the results of applying Hapke modeling to our data set. The best
spectral fit is obtained with a mixture of crystalline water ice (grain sizes
smaller than 60 micron) with a few percent of amorphous carbon. Improvements to
the fit are obtained by adding ~10% of amorphous water ice. Additionally, we
used the IFU-reconstructed images to measure the relative astrometric position
of the largest satellite Hi`iaka and determine its orbital elements. An orbital
solution was computed with our genetic-based algorithm GENOID and our results
are in full agreement with recent results.Comment: Accepted for publication in A&
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