Depicting the tree of life in museums: guiding principles from psychological research

The Tree of Life is revolutionizing our understanding of life on Earth, and, accordingly, evolutionary trees are increasingly important parts of exhibits on biodiversity and evolution. The authors argue that in using these trees to effectively communicate evolutionary principles, museums need to take into account research results from cognitive, developmental, and educational psychology while maintaining a focus on visitor engagement and enjoyment. Six guiding principles for depicting evolutionary trees in museum exhibits distilled from this research literature were used to evaluate five current or recent museum trees. One of the trees was then redesigned in light of the research while preserving the exhibit’s original learning goals. By attending both to traditional factors that influence museum exhibit design and to psychological research on how people understand diagrams in general and Tree of Life graphics in particular, museums can play a key role in fostering 21st century scientific literacy

Investigating a training supporting shared decision making (IT'S SDM 2011): study protocol for a randomized controlled trial

<p/> <p>Background</p> <p>Shared Decision Making (SDM) is regarded as the best practice model for the communicative challenge of decision making about treatment or diagnostic options. However, randomized controlled trials focusing the effectiveness of SDM trainings are rare and existing measures of SDM are increasingly challenged by the latest research findings. This study will 1) evaluate a new physicians' communication training regarding patient involvement in terms of SDM, 2) validate SDM_MASS, a new compound measure of SDM, and 3) evaluate the effects of SDM on the perceived quality of the decision process and on the elaboration of the decision.</p> <p>Methods</p> <p>In a multi-center randomized controlled trial with a waiting control group, 40 physicians from 7 medical fields are enrolled. Each physician contributes a sequence of four medical consultations including a diagnostic or treatment decision.</p> <p>The intervention consists of two condensed video-based individual coaching sessions (15min.) supported by a manual and a DVD. The interventions alternate with three measurement points plus follow up (6 months).</p> <p>Realized patient involvement is measured using the coefficient SDM_MASSdrawn from the Multifocal Approach to the Sharing in SDM (MAPPIN'SDM) which includes objective involvement, involvement as perceived by the patient, and the doctor-patient concordance regarding their judges of the involvement. For validation purposes, all three components of SDM_MASSare supplemented by similar measures, the OPTION observer scale, the Shared Decision Making Questionnaire (SDM-Q) and the dyadic application of the Decisional Conflict Scale (DCS). Training effects are analyzed using t-tests. Spearman correlation coefficients are used to determine convergent validities, the influence of involvement (SDM_MASS) on the perceived decision quality (DCS) and on the elaboration of the decision. The latter is operationalised by the ELAB coefficient from the UP24 (Uncertainty Profile, 24 items version).</p> <p>Discussion</p> <p>Due to the rigorous blinded randomized controlled design, the current trial promises valid and reliable results. On the one hand, we expect this condensed time-saving training to be adopted in clinical routine more likely than previous trainings. On the other hand, the exhaustivity of the MAPPIN'SDM measurement system qualifies it as a reference measure for simpler instruments and to deepen understanding of decision-making processes.</p> <p>Trial registration</p> <p>Current Controlled Trials <a href="http://www.controlled-trials.com/ISRCTN78716079">ISRCTN78716079</a></p

Evolutionary Determinants of Genetic Variation in Susceptibility to Infectious Diseases in Humans

Although genetic variation among humans in their susceptibility to infectious diseases has long been appreciated, little focus has been devoted to identifying patterns in levels of variation in susceptibility to different diseases. Levels of genetic variation in susceptibility associated with 40 human infectious diseases were assessed by a survey of studies on both pedigree-based quantitative variation, as well as studies on different classes of marker alleles. These estimates were correlated with pathogen traits, epidemiological characteristics, and effectiveness of the human immune response. The strongest predictors of levels of genetic variation in susceptibility were disease characteristics negatively associated with immune effectiveness. High levels of genetic variation were associated with diseases with long infectious periods and for which vaccine development attempts have been unsuccessful. These findings are consistent with predictions based on theoretical models incorporating fitness costs associated with the different types of resistance mechanisms. An appreciation of these observed patterns will be a valuable tool in directing future research given that genetic variation in disease susceptibility has large implications for vaccine development and epidemiology

Acculturation of Pacific mothers in New Zealand over time: findings from the Pacific Islands Families study

Immigration and acculturation are increasingly recognized as important explanatory factors for health disparities, although their impact on oral health is less well understood. This study investigates the relationship between Pacific children's cultural orientation and oral health, after adjusting for potentially moderating and confounding variables

Influences of Domestication and Island Evolution on Dental Growth in Sheep

Abstract: Domestication and island evolution can lead to changes of life history along the slow-fast gradient. Shifts of life history patterns, in turn, are potentially related to alterations of patterns and timing of tooth eruption. Schultz’s rule predicts an earlier eruption of molars relative to premolars as fecundity increases during the domestication process. On the other hand, evolution on a predator-free, resource limited island might lead to a generally slow life history and delayed tooth eruption, as in the Plio-Pleistocene Balearic caprine Myotragus. In this study, we investigate tooth eruption and its relation to life history in a unique sheep population that is an example of both domestication and island evolution: the ancient and feral Soay sheep (Ovis aries) of the St. Kilda archipelago, Scotland. Tooth eruption timing and sequence is investigated in a comparative framework featuring new data on other domestic sheep (O. aries), including European mouflon (O. a. musimon), as well as wild sheep (O. vignei, O. cycloceros, O. arkal, O. orientalis, O. ammon). These data indicate that the order of eruption is similar in wild and domestic sheep, despite the fundamental life history changes that came about with domestication. However, in contrast to other domestic sheep breeds, Soay sheep erupt their teeth at an absolute older age and also tend to grow more slowly, which resembles the evolutionary trend in island-adapted Myotragus. Despite these similarities, Soay sheep do not share the slow life history pattern inferred for Myotragus, highlighting the distinctive nature of tooth eruption in Soay sheep

An Agent-based Approach for Structured Modeling, Analysis and Improvement of Safety Culture

Safety culture is broadly recognized as important for operational safety in various fields, including air traffic management, power plant control and health care. Previous studies addressed characterization and assessment of safety culture extensively. Nevertheless, relations between safety culture and formal and informal organizational structures and processes are yet not well understood. To address this gap, a new, formal, agent-based approach is proposed. This paper shows the application of the approach to an air navigation service provider, including structured modeling, analysis and identification of improvement strategies for the organizational safety culture. The model results have been validated using safety culture data that had been achieved by an independent safety culture survey study. © 2011 The Author(s)

Iberomeryx minor (Mammalia, Artiodactyla) from the Early Oligocene of Soulce (Canton Jura, NW Switzerland): systematics and palaeodiet

The primitive ruminant genus Iberomeryx is poorly documented, as it is essentially only known from rare occurrences of dental remains. Therefore, the phylogeny and palaeobiology of Iberomeryx remain rather enigmatic. Only two species have been described: the type species I. parvus from the Benara locality in Georgia, and the Western European species I. minor reported from France, Spain, and Switzerland. Iberomeryx savagei from India has recently been placed in the new genus Nalameryx. All these localities are dated to the Rupelian and correspond mainly to MP23 (European mammal reference level). Based on the short height of the tooth-crown and the bunoselenodont pattern of the molars, Iberomeryx has often been considered as a folivore/frugivore. The I. minor remains from Soulce (NW Switzerland) are preserved in Rupelian lacustrine lithographic limestones. One specimen from this locality represents the most complete mandible of the taxon with a partially persevered ramus. Moreover, the unpreserved portion of the mandible left an imprint in the sediment, permitting the reconstruction of the mandible outline. Based on a new description of these specimens, anatomical comparisons and Relative Warp Analysis (24 landmarks) of 94 mandibles (11 fossil and 83 extant) from 31 ruminant genera (10 fossil and 21 extant) and 40 species (11 fossil and 29 extant), this study attempts a preliminary discussion of the phylogeny and the diet of the species I. minor. The results permit to differentiate Pecora and Tragulina on the first principal component axis (first Relative warp) on behalf of the length of the diastema c/cheek teeth, the length of the premolars and the angular process. The mandible shape of I. minor is similar to those of the primitive Tragulina, but it differs somewhat from those of the extant Tragulidae, the only extant family in the Tragulina. This difference is essentially due to a stockier mandible and a deeper incisura vasorum. However, in consideration of the general pattern of its cheek teeth, I. minor as well as possibly Nalameryx should be considered to represent the only known primitive Tragulidae from the Oligocene. Moreover, I. minor should have been a selective browser (fruit and dicot foliage) but, similarly to small Hypertragulidae and Tragulidae, may also have exceptionally consumed animal matter