Some reasons to build a new laser Doppler flowmeter to monitor microvascular blood flow

Disturbance in the blood microcirculation is a frequent complication in a number of common diseases including diabetes, arteriosclerosis and Raynaud’s phenomenon. In order to effectively diagnose these diseases, clinical tools able to monitor non-invasively the microvascular perfusion are required. For that purpose several techniques have been proposed. Among them, laser Doppler flowmetry (LDF) has been developed over the years, from experimental tools into commercial products, and several thousands of publications cite its use in the scientific literature. Nowadays, the LDF technique is commonly proposed in diverse applications. However, the dependence of the LDF signal on the microvascular architecture is still not known. A scientific understanding and knowledge of the LDF signal origin is not yet accessible to clinicians. Some studies proposed the use of different fiber separations or several wavelengths in order to modify the sampling depth of the LDF technique. However, further work is required to have knowledge and control over the mean sampling depth (and hence volume) in skin tissue

Effect of Sr substitution on superconductivity in Hg2(Ba1-ySry)2YCu2O8-d (part2): bond valence sum approach of the hole distribution

The effects of Sr substitution on superconductivity, and more particulary the changes induced in the hole doping mechanism, were investigated in Hg2(Ba1-ySry)2YCu2O8-d by a "bond valence sum" analysis with Sr content from y = 0.0 to y = 1.0. A comparison with CuBa2YCu2O7-d and Cu2Ba2YCu2O8 systems suggests a possible explanation of the Tc enhancement from 0 K for y = 0.0 to 42 K for y = 1.0. The charge distribution among atoms of the unit cell was determined from the refined structure, for y = 0.0 to 1.0. It shows a charge transfer to the superconducting CuO2 plane via two doping channels pi(1) and pi(2), i.e. through O2(apical)-Cu and Ba/Sr-O1 bonds respectively.Comment: 13 pages, 5 figures, accepted for publication in Journal of Physics: Condensed Matte

High-density genetic mapping for coffee leaf rust resistance.

Coffee leaf rust caused by the fungus Hemileia vastatrix causes considerable economic losses for coffee producers. Although agrochemical products can provide sufficient disease control, the use of resistant cultivars is a safer alternative. This resistance may be constrained by one or a few genetic factors, mainly those found in material originating from interspecific hybrids. In this study, the genetic analysis of an F2 population consisting of 224 plants derived from a crossing of Híbrido de Timor UFV 427-15 (resistant) with Catuaí Amarelo IAC 30 (susceptible) showed that a dominant gene confers the resistance of coffee to race II of H. vastatrix. From a genetic map saturated with 25 amplified fragment length polymorphism (AFLP) markers linked to the resistance gene, we developed a high-density genetic map with six sequence-characterized amplified region (SCAR) markers delimiting a chromosomal region of 9.45 cM and flanking the dominant gene at 0.7 and 0.9 cM. This is the first saturated and high-density genetic map obtained from this region containing the resistance gene. The results of this study are of great importance for the introduction of molecular markers for marker-assisted selection; they will also facilitate studies related to the cloning, structure, and function of race-specific genes involved in the resistance of coffee trees to H. vastatrix

Experimental study of fragmentation products in the reactions 112Sn + 112Sn and 124Sn + 124Sn at 1 AGeV

Production cross-sections and longitudinal velocity distributions of the projectile-like residues produced in the reactions 112Sn + 112Sn and 124Sn + 124Sn both at an incident beam energy of 1 AGeV were measured with the high-resolution magnetic spectrometer, the Fragment Separator (FRS) of GSI. For both reactions the characteristics of the velocity distributions and nuclide production cross sections were determined for residues with atomic number Z $\geq$ 10. A comparison of the results of the two reactions is presented.Comment: 14 pages, 12 figure

Mapeamento genético de marcadores AFLP ligados ao gene de resistência do híbrido de timor à Hemileia vastatrix.

A ferrugem alaranjada do cafeeiro causada por Hemileia vastatrix é tida como a mais devastadora doença do cafeeiro. Este trabalho objetivou estudar a herança gênica e a identificação de marcadores moleculares ligados ao gene que confere resistência a esta doença. Para este estudo foram utilizados a população F2 (160 indivíduos), o retrocruzamento resistente (RCr, 20 indivíduos) e o suscetível (RCs, 135 indivíduos), derivados do cruzamento entre o Híbrido de Timor UFV 427-15, genitor resistente e o suscetível Catuai amarelo UFV 2143-236. A análise da segregação das populações, em estudo, indicou que um único gene dominante, presente no acesso do Híbrido de Timor UFV 427-15, é responsável pela resistência. Foram utilizadas as metodologias de BSA (Bulked Segregant Analysis) e AFLP, e analisadas 852 combinações de primers, que permitiram identificar três marcadores ligados ao gene de resistência localizados flanqueando ambos os lados, e distantes a 8.69, 20.50 e 25.10 cM. Estes são os primeiros marcadores identificados para o gene de resistência a ferrugem presente no Híbrido de Timor, e auxiliarão na seleção em programas de melhoramento para a resistência a ferrugem no Brasil

X-point collapse and saturation in the nonlinear tearing mode reconnection

We study the nonlinear evolution of the resistive tearing mode in slab geometry in two dimensions. We show that, in the strongly driven regime (large Delta'), a collapse of the X-point occurs once the island width exceeds a certain critical value ~1/Delta'. A current sheet is formed and the reconnection is exponential in time with a growth rate ~eta^1/2, where eta is the resistivity. If the aspect ratio of the current sheet is sufficiently large, the sheet can itself become tearing-mode unstable, giving rise to secondary islands, which then coalesce with the original island. The saturated state depends on the value of Delta'. For small Delta', the saturation amplitude is ~Delta' and quantitatively agrees with the theoretical prediction. If Delta' is large enough for the X-point collapse to have occured, the saturation amplitude increases noticeably and becomes independent of Delta'.Comment: revtex4, 4 pages, 18 figure

Factors shaping young tourists' intentions to travel to Greece, Israel and Portugal: Universal or idisyncratic perceptions of young Greeks, Israelis and Portugese?

Tourism constitutes an important branch of economy, especially in countries experiencing economic crisis and harsh socio-political events. The current study compares the intention of young people from three different countries – Greece, Israel and Portugal - to travel to two selected destinations. For each country of origin the other two countries were the destination of interest. This research examined the factors affecting young tourists' intention to travel to different destinations assuming that those determinants depend on the country of origin as well as on the destination country. The sample comprised of 648 students: Israelis (277), Portuguese (200), Greeks (171). The research questionnaire was distributed in Israeli, Greek and Portuguese academic institutions in 2014. The results indicate that over half of the Israelis intend to visit Greece or Portugal. The majority of the Portuguese anticipate visiting Greece, while only 32.5% expect to visit Israel. Among the Greeks nearly 50% intend to visit Portugal and do not intend to visit Israel. The study showed that the main factors affecting the decisions of young Portuguese to travel to Israel were: the image of Israel, the perceived risk of traveling to a country with political unrest and the number of trips abroad. The main factors affecting the decisions of young Greeks were the perceived risk of traveling to a country with political unrest and Israel's image. Israelis' decision to travel to Greece was affected by their image of Greece; the Portuguese also took into account the perceived risk regarding economic situation. For Israelis, considering Portugal as a traveling destination was related to the destination's image. The Greeks were affected by the number of Facebook friends and the Innovation, Entrepreneurship and Digital Ecosystems perceived economic risk. This research suggests that the socio-economic, political context of the country of origin and of the tourist destination plays an important role in young tourists' travelling-related decision-making.info:eu-repo/semantics/publishedVersio

Analyzing the effect of socio-political context on tourism: perceptions of young tourists in Greece, Portugal and Israel

International crises that affect tourism, such as terror attacks, political unrest, and economic crises have become more frequent, and their influence has become broader. The influence of such extreme events depends on their salience in the tourists' awareness. Hence, it is important to understand the mechanisms underlying tourists' selection of travel destinations, especially their perceptions of crisis-related events and the impact of the sociopolitical and economic context in their countries of origin. The current study examined how the socio-political and economic context in the home countries of potential young tourists affected their selection of travel destinations. The objective was to elucidate how the salience of various crises (economic and political) in the tourists' perceptions, due to their experiences at home, color their construal of destinations affected by similar hazards and influence their travel intentions. The study focused on student tourists from Israel, Greece, and Portugal. Today about a fifth of international tourism is based on young people, especially students. These countries were chosen since Greece and Portugal are in the midst of economic crises. In addition, Greece and Portugal have experienced political instability, while Israel has security-related problems (including terrorist incidents). In 2013, a total of 648 students, responded to a questionnaire that included questions concerning attitudes and risk perceptions regarding travel to destinations with various risk hazards as well as socio-demographic details. The results indicate that over half of the Israelis intend to visit Greece or Portugal. The majority of the Portuguese intend to visit Greece, while less than a third of them intend to visit Israel. About half of the Greeks intend to visit Portugal, and most of them do not intend to visit Israel. The results indicate that greater perceived importance of economic crises mitigates the intention to travel to destinations with economic crises for tourists from origin countries that are also marked by economic crises, such as Greece and Portugal. However, for tourists from Israel, a country with a relatively stable economy, issues related to the economy barely affect their intention to travel to the other two countries. The findings also suggest that Greeks and Portuguese who are highly concerned about political unrest are unlikely to select Israel as a tourist destination. In addition, strong apprehension regarding terrorism impedes the intention to travel to destinations marked by terrorist incidents, such as Israel. The current research contributes to the existing literature by highlighting the impact of travelers' personal previous experience with crisis on their risk perceptions and in turn on their intentions to travel to countries with similar risks. Therefore, in a world where such incidents are on the rise, understanding tourists' risk perceptions and behavior and the factors influencing their destination-related decisions are crucial for countries that wish to increase the numbers of incoming tourists.info:eu-repo/semantics/publishedVersio