31 research outputs found
Association between statin therapy and outcomes in critically ill patients: a nested cohort study
- Author
- AP Liappis
- B Zingarelli
- BM Livingston
- CP Martin
- DG Hackam
- EM Mortensen
- FL Ferreira
- G Weitz-Schmidt
- G Weitz-Schmidt
- G Weitz-Schmidt
- Hani M Tamim
- K Iijima
- KA Weant
- KC Yang
- L Kronmann
- LM Blanco-Colio
- M Terblanche
- ME Falagas
- MM Levy
- P Dobesh
- P Kruger
- PP Dobesh
- R Fernandez
- RW Thomsen
- S Aslanyan
- S Christensen
- S Janda
- Shmeylan A Al Harbi
- SR Majumdar
- U Stenestrand
- WA Knaus
- Y Almog
- Y Arabi
- Y Arabi
- Yaseen M Arabi
- YM Arabi
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
Association of knowledge on ART line of treatment, scarcity of treatment options and adherence
- Author
- C Kanjala
- CA Koss
- Charles Muiruri
- D Boateng
- DL Paterson
- DR Bangsberg
- DR Bangsberg
- DR Bangsberg
- E Slaymaker
- Eileen S. Lirhunde
- Habib O. Ramadhani
- HO Ramadhani
- HO Ramadhani
- IB Wilson
- J Gare
- JJ Parienti
- John A. Bartlett
- Julian B. Mushi
- LM Terblanche
- M Mbonye
- MA Thompson
- Michael Omondi
- MS Cohen
- R Demessie
- R Zachariah
- SA Safren
- SP Wasti
- T Bärnighausen
- V Senkomago
- Venance P. Maro
- Y Potchoo
- Y Sasaki
- Z El-Khatib
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
- A Abbott
- A Abou-Raya
- A Aljandali
- A Ambesi-Impiombato
- A Aydin
- A Balcerczyk
- A Besarab
- A Brzezinski
- A Campbell
- A Carrillo-Vico
- A Cavalli
- A Chattopadhyay
- A Chattopadhyay
- A Cherubini
- A Dey
- A Doms
- A Donovan
- A Donovan
- A Dávalos
- A Gaeta
- A Garny
- A Gnjec
- A Gomes
- A Gopalakrishnan
- A Hald
- A Henney
- A Hirayama
- A Hoffmann
- A Huber
- A Hugman
- A Iannetti
- A Ide-Ektessabi
- A Jacobs
- A Jeyabalan
- A Kahvejian
- A Karrar
- A Kasztler
- A Kibel
- A Kocyigit
- A Kotha
- A Kumral
- A Lass
- A Lecube
- A Lewén
- A Lotery
- A Maggio
- A Malek
- A Malik
- A Mantovani
- A Matsuzawa
- A Mitra
- A Monge
- A Murakami
- A Murakami
- A Murakami
- A Murakami
- A Mutti
- A Nijnik
- A Nunomura
- A Nunomura
- A Patt
- A Persson
- A Pietrangelo
- A Piga
- A Pirat
- A Post
- A Pradhan
- A Protti
- A Rattner
- A Ravati
- A Rehman
- A Reynolds
- A Richmond
- A Roetto
- A Roetto
- A Rostom
- A Rumbold
- A Russo
- A Rötig
- A Saltelli
- A Saltelli
- A Sandek
- A Sassano
- A Scalbert
- A Scalbert
- A Scalbert
- A Sica
- A Smahi
- A Sola
- A Stintzi
- A Szewczyk
- A Taguchi
- A Tedgui
- A Terman
- A Terman
- A Terman
- A Undas
- A Virdis
- A Wagner
- A Wagner
- A Wagner
- A Wagner
- A Wojas-Pelc
- A Wong
- A Xu
- A Yoritaka
- A Yoshimura
- A-L Barabási
- AA Andreadis
- AA Borisy
- AA Farooqui
- AA Qutub
- AA Qutub
- AA Vlessis
- AB Nathens
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- AB Parsons
- AB Thompson
- AB Thomson
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- Ad hoc committee on systemic lupus erythematosus response criteria for fatigue
- ADL van der
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- B Chakravarti
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- B Desoize
- B Drayer
- B Faller
- B Goodell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
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- Y Ge
- Y Gilgun-Sherki
- Y Haruna
- Y Honda
- Y Hua
- Y Ikeda
- Y Jiao
- Y Jung
- Y Ke
- Y Ke
- Y Kohgo
- Y Kohgo
- Y Levites
- Y Li
- Y Okatani
- Y Okatani
- Y Sai
- Y Sai
- Y Sun
- Y Takada
- Y Wang
- Y Wang
- Y Wei
- Y Wei
- Y Wu
- Y Wu
- Y Zhang
- Y Zhang
- Y Zhang
- Y Zhao
- Y Zheng
- YE Henrotin
- YF Chu
- YH Lee
- YH Suh
- YH Wei
- YJ Surh
- YJ Surh
- YJ Surh
- YK Wu
- YM Kim
- YS Keum
- YS Sohn
- YX Ma
- YZ Fang
- Z Cai
- Z Cai
- Z Cheng
- Z Pei
- Z Serdar
- Z Tong
- Z Tong
- Z Yu
- Z Zhang
- ZD Liu
- ZD Liu
- ZE Karanjawala
- ZE Suntres
- ZI Cabantchik
- ZZ Chong
- ZZ Chong
- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.
- Author
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- Wang D
- Wang F
- Wang G
- Wang H
- Wang H
- Wang J
- Wang J
- Wang J
- Wang J
- Wang J
- Wang K
- Wang L
- Wang L
- Wang L
- Wang S
- Wang S
- Wang S
- Wang T
- Wang W
- Wang X-L
- Wang Y
- Wang Y
- Wang Z
- Wang Z
- Wang Z
- Wang Z
- Ward J
- Wasmund C
- Wassall R
- Watanabe Oliveira HR
- Watson A
- Watson N
- Watt P
- Waugh D
- Waweru P
- Waworuntu N
- Waymouth E
- Weatherall L
- Weatherill J
- Webb S
- Weber E
- Wei J
- Weimann J
- Weller D
- Welsh S
- Wen XH
- Wen Y
- Wen Z
- Wendling PR
- Wessels JD
- Wetzel P
- Weyland A
- White S
- White S
- whitehouse A
- Whitman Z
- Whittle N
- Whitworth H
- Whysall K
- Wibrandt I
- Wickboldt N
- Wickenhauser R
- Wid WM
- Widmark C
- Wiegand-Loehnert C
- Wighton E
- Wigmore G
- Wijeysundera D
- Wikner M
- Wild J
- Wildes T
- Wildi S
- Williams A
- Williams M
- Williams S
- Wilscott-Davids C
- Wilson A
- Wilson D
- Wilson L
- Wilson N
- Wima S
- Winch D
- Winstone U
- Winterton D
- Wir WM
- Wise R
- Wittmann M
- Wolfer A
- Wollaston J
- Wong C
- Wong CW
- Wong JY
- Wong K
- Wong KWK
- Wong SM
- Wong T
- Wong WL
- Woodgate A
- Woolsey A
- Woon YL
- Worreth M
- Wouters P
- Wrench I
- Wright S
- Wu C
- Wu C
- Wu J
- Wu J
- Wu Q
- Wu S
- Wyffels P
- Wylie K
- Xia J
- Xia Y
- Xia Z-Y
- Xiao W
- Xiao W
- Xie G
- Xie J
- Xie J
- Xie K
- Xifara A
- Xiong X
- Xiong Y
- Xouplidis K
- Xu G-J
- Xu L
- Xu L
- Xu Q
- Xu S
- Xue R
- Yagnik A
- Yan Y
- Yang J
- Yang L
- Yang Q
- Yang S
- Yang T
- Yang Y
- Yao S
- Yao Y
- Yap HL
- Yarwood J
- Yassaee A
- Ye H
- Ye H
- Yegnaram S
- Yeh E
- Yin N
- Yip CP
- Yong J
- Yu HC
- Yu S
- Yu T
- Yu Y
- Yuan D
- Yuan F
- Yuan J
- Yuan J
- Yuan Y
- Yuliana A
- Zaimi D
- Zakynthinos S
- Zamudio D
- Zangrillo A
- Zapata DDM
- Zbitnew G
- Zeidan L
- Zeng Q
- Zerman L
- Zettergren J
- Zhang B
- Zhang E
- Zhang H
- Zhang H
- Zhang H
- Zhang J
- Zhang K
- Zhang L
- Zhang M
- Zhang M
- Zhang Q
- Zhang R
- Zhang S
- Zhang W
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhao B
- Zhao B
- Zhao C
- Zhao J
- Zhao J
- Zhao L
- Zhao L
- Zhao S
- Zhao T
- Zhao W
- Zhao W
- Zhao X
- Zhen J
- Zheng K
- Zheng L
- Zheng T
- Zhong Y
- Zhou C
- Zhou D
- Zhou H
- Zhou H
- Zhou J
- Zhou J
- Zhou J
- Zhou X-J
- Zhu X
- Zhu X
- Zhu Y
- Zhu Z
- Zhuang X
- Zilis G
- Zin NHM
- Zingerle N
- Zingg U
- Zoerner F
- Zonneveldt H
- Zou X
- Zoulamoglou M
- Zsisku L
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2016
- Field of study
BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700
Plant species diversity for sustainable management of crop pests and diseases in agroecosystems: a review
- Author
- A Calegari
- A Fereres
- A Ratnadass
- A Sarniguet
- A Sarniguet
- AA Brunt
- AB Pepperman
- AG Power
- AHC Bruggen Van
- AHEE Kaut
- AL Rypstra
- Alain Ratnadass
- AM Primavesi
- AM Reynolds
- AM Shelton
- AM Shelton
- AP Andrianaivo
- AR Weinhold
- AT Simmons
- B Leroi
- B Ricci
- BGH Timmermans
- C Dordas
- C Staver
- CA Palm
- CC Mundt
- CE Mitchell
- CI Nicholls
- CLC Lelivelt
- CM Cox
- CM Messiaen
- CM Messiaen
- CP Ohmart
- CRR Hooks
- D Pimentel
- D Tilman
- D Wood
- DA Andow
- DA Landis
- DA Landis
- DA Wardle
- DH Long
- DJ Mills
- DK Letourneau
- DM Weller
- DN Byrne
- DR Walters
- E Blanchart
- E Malézieux
- E Scopel
- EC Bernard
- F Chaboussou
- F Schulthess
- FA Rodrigues
- FJ Bannon
- FJ Gommers
- FJJA Bianchi
- FL Wäckers
- FR Badenes-Perez
- G Caubel
- G Jones
- G Schroth
- GC Jahn
- GC Papavizas
- GD Leroux
- GJK Griffiths
- GL Teetes
- GR Stirling
- H Hauggaard-Nielsen
- H Hokkanen
- H Tian
- HA Smith
- HC Evans
- HC Evans
- HF Emden Van
- HJ Smith
- HK Ngugi
- HS Rataul
- I Perfecto
- I Perfecto
- I Perfecto
- IB Lavandero
- IH Mian
- III Uvah
- IMB Knudsen
- IMG Vollhardt
- J Avelino
- J Avelino
- J Avelino
- J A’Brook
- J Beer
- J Berg Van den
- J Fargues
- J Halaj
- J Halaj
- J Kayeke
- J LaMondia
- J Mailloux
- J Muller
- J Styrsky
- J Terblanche
- J Theunissen
- J Vandermeer
- JA Elzinga
- JA Kirkegaard
- JA Kirkegaard
- JA McMurtry
- JA Mouen Bedimo
- Jacques Avelino
- JB Ristaino
- JB Smithson
- JC Zadoks
- JE Banks
- JE Banks
- JE Pasek
- JG Smith
- JKM Brown
- JM Hickman
- JM Krupinsky
- JM Tylianakis
- JN Matthiessen
- JN Thompson
- JN Thompson
- JR Miller
- JR Prasifka
- JR Yu
- JS Virk
- JSO Epila
- JW Klopper
- JW Klopper
- K Ammann
- K Asman
- K Paustian
- K Scholte
- K Scholte
- K Scholte
- K Thorup-Kristensen
- K-H Wang
- KA Robinson
- KE Dover
- KH Wang
- KH Wang
- L Bush
- L Hilje
- L Séguy
- LA Weston
- LCA Barbosa
- LE Datnoff
- LEB Blum
- LM Schoonhoven
- LR Baggen
- M Bigger
- M Liebman
- M Sarwar
- M Schloter
- M Wolfe
- MA Altieri
- MA Altieri
- MA Boudreau
- MA Latheef
- MA Latheef
- MA Latheef
- MA Nogueira
- MH Schmidt
- MH Schmidt
- MJ Way
- MR Colley
- MR Finckh
- MTJ Johnson
- N Greco
- N Kokalis-Burelle
- N Ntahimpera
- NA Schellhorn
- NA Schlathoelter
- NE Vicente
- NP Castilla
- O Gomez-Rodriguez
- O Youm
- OL Kvedaras
- OL Kvedaras
- OT Lewis
- P Davet
- P Feeny
- P Ferron
- P Mele Van
- PA Matson
- Paula Fernandes
- PD King
- PD Peterson
- PE Rasmussen
- PG Tillman
- PM Room
- PR Grundy
- R Mac Sorley
- R Miethling
- R Rodriguez-Kabana
- RB Root
- RE Peachey
- RH Maclean
- RJ Cook
- Robert Habib
- RP Jaques
- RPP Almeida
- RS Kanwar
- RW Mc Leod
- S England
- S Finch
- S Finch
- S Neuman
- S Nouhuys Van
- S Sanchez de Viala
- SA Tiyagi
- SB Hill
- SH Ou
- SL Lima
- SL Vail
- SM Cook
- SM Kimani
- SN Sall
- SP Foster
- SR Sharma
- SR Voleti
- T Brévault
- T Dawson
- T Tscharntke
- T Tscharntke
- TCJ Turlings
- TE Condeso
- TE Perkins
- TJ Ridsill Smith
- TL Widmer
- TL Widmer
- V Insunza
- V Vilich-Meller
- VSA Odunfa
- VV Michel
- W Jackson
- WB McGill
- WJ Mattson Jr
- WML Crombie
- XG Zhou
- Y Oka
- Y Spiegel
- Y Zhu
- Z-X Lu
- ZR Khan
- ZR Khan
- ZR Khan
- ZR Khan
- ZR Khan
- Ö Östman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: a randomized double-blind placebo controlled clinical trial
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Survival and Hsp70 Gene Expression in Plutella xylostella and Its Larval Parasitoid Diadegma insulare Varied between Slowly Ramping and Abrupt Extreme Temperature Regimes
- Author
- AA Hoffmann
- BJ Sinclair
- C Wu
- Cathy Coutu
- CL Lyons
- D Waagner
- Diana Bekkaoui
- DM McMillan
- Dwayne Hegedus
- I Karl
- J Overgaard
- J Overgaard
- JG Kiang
- JG Sørensen
- JM Scriber
- JS Terblanche
- JS Terblanche
- JS Terblanche
- Juliana Soroka
- KA Mitchell
- Lloyd Dosdall
- LM Dosdall
- M Belén Arias
- M Sarfraz
- Md Habibullah Bahar
- ME Feder
- MH Bahar
- MJ Furlong
- MJ Jr Angilletta
- NR Andrew
- P Xu
- R Bosch
- R Mahroof
- S Bahrndorff
- S Sonoda
- S Taylor
- SAS Institute
- SL Chown
- SL Chown
- Suzannah Rutherford
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Cold tolerance is similar but heat tolerance is higher in the alien insect Trichocera maculipennis than in the native Parochlus steinenii in Antarctica
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Intraoperative ultrasound during bile tract surgery
- Author
- A Escalon
- A Evander
- A Peracchia
- A Puglionisi
- AM Gaetano De
- B Eiseman
- B Launois
- B Sigel
- B Sigel
- B Sigel
- B Sigel
- B Sigel
- C Huguet
- C Tremolada
- CA Herbest
- CR Voyles
- D Houssin
- DG Gibby
- EA Detich
- G Gozzetti
- GM Gazzaniga
- H Bismuth
- H Bismuth
- IC Langer
- J Machi
- J Terblanche
- JJ Jakimowicz
- JJ Jakimowicz
- L Bolondi
- LH Blumgart
- LH Blumgart
- LM Vincent
- MA Adson
- MC Plainfosse
- MC Plainfosse
- MD Custer
- MJ Hart
- R Chardavonne
- R Ottow
- R Soupault
- RC Hall
- RC Purdon
- RJ Lane
- RJ Lane
- RJ Lane
- RM Beazley
- RR Knight
- S Bengmark
- SE Dudely
- T Tsuzuki
- WP Longmire Jr.
- WR Chitwood
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1989
- Field of study
Cold tolerance is unaffected by oxygen availability despite changes in anaerobic metabolism
- Author
- A Malmendal
- AM Makarieva
- AM Wade
- B Groenewald
- BJ Sinclair
- BYF Goller
- CF Herreid
- CH Basson
- CJ Klok
- CM Williams
- CM Williams
- DJ Marshall
- DP Yeager
- DR Joanisse
- GD Yocum
- H Colinet
- H Colinet
- HA MacMillan
- HA MacMillan
- HA MacMillan
- HM Lease
- HO Pörtner
- J Harrison
- J Lemire
- J Overgaard
- J Overgaard
- J Xia
- J Xia
- JRB Lighton
- JRB Lighton
- JRB Lighton
- JRB Lighton
- JS Terblanche
- JS Terblanche
- KJ Greenlee
- L Boardman
- L Boardman
- L Boardman
- L Boardman
- L Boardman
- LM Pujol-Lereis
- M Robert Michaud
- ME Dillon
- MM Stevens
- MR Michaud
- P Holter
- PG Fields
- RE Lee
- RE Lee
- S Ben-Yehoshua
- S Clusella-Trullas
- S Slotsbo
- S Zhou
- S-P Huang
- SG Goto
- SJ Coulson
- SK Hetz
- SM Vereshtchagin
- SP Hazell
- T Grové
- TL Nilson
- V Callier
- V Koštál
- WA Van Voorhies
- WCEP Verberk
- WCEP Verberk
- WCEP Verberk
- WW Hoback
- Y Benjamini
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study