Cell biology, SevERing mitochondria

The endoplasmic reticulum is an active participant in the division of another organelle, the mitochondrion

Characterization of causes of signal phase and frequency instability Final report

Characteristic instabilities in phase and frequency errors of reference oscillator

On (2,3)-agreeable Box Societies

The notion of $(k,m)$-agreeable society was introduced by Deborah Berg et al.: a family of convex subsets of $\R^d$ is called $(k,m)$-agreeable if any subfamily of size $m$ contains at least one non-empty $k$-fold intersection. In that paper, the $(k,m)$-agreeability of a convex family was shown to imply the existence of a subfamily of size $\beta n$ with non-empty intersection, where $n$ is the size of the original family and $\beta\in[0,1]$ is an explicit constant depending only on $k,m$ and $d$. The quantity $\beta(k,m,d)$ is called the minimal \emph{agreement proportion} for a $(k,m)$-agreeable family in $\R^d$. If we only assume that the sets are convex, simple examples show that $\beta=0$ for $(k,m)$-agreeable families in $\R^d$ where $k<d$. In this paper, we introduce new techniques to find positive lower bounds when restricting our attention to families of $d$-boxes, i.e. cuboids with sides parallel to the coordinates hyperplanes. We derive explicit formulas for the first non-trivial case: the case of $(2,3)$-agreeable families of $d$-boxes with $d\geq 2$.Comment: 15 pages, 10 figure

Graph-Convolutional Autoencoder Ensembles for the Humanities, Illustrated with a Study of the American Slave Trade

We introduce a graph-aware autoencoder ensemble framework, with associated formalisms and tooling, designed to facilitate deep learning for scholarship in the humanities. By composing sub-architectures to produce a model isomorphic to a humanistic domain we maintain interpretability while providing function signatures for each sub-architectural choice, allowing both traditional and computational researchers to collaborate without disrupting established practices. We illustrate a practical application of our approach to a historical study of the American post-Atlantic slave trade, and make several specific technical contributions: a novel hybrid graph-convolutional autoencoder mechanism, batching policies for common graph topologies, and masking techniques for particular use-cases. The effectiveness of the framework for broadening participation of diverse domains is demonstrated by a growing suite of two dozen studies, both collaborations with humanists and established tasks from machine learning literature, spanning a variety of fields and data modalities. We make performance comparisons of several different architectural choices and conclude with an ambitious list of imminent next steps for this research.Comment: More in-depth technical companion to "A general neural ensemble technique to support traditional scholarship", Digital Humanities 202

Spectral analysis of oscillation instabilities in frequency standards

Phase and frequency fluctuations, inherent in oscillators used as frequency standards, are measured over spectral frequency range of 1 Hz to 5 kHz. Basic measurement system consists of electromechanical phase-locked loop that extracts phase and frequency fluctuations and error multiplier that extends threshold sensitivity

Depoliticizing Sovereign Wealth Funds Through International Arbitration

Since their inception in the 1950s, Sovereign Wealth Funds (SWFs) have dramatically expanded with the purpose of investing government revenue and maximizing returns for states with surplus funds. While SWF investments benefit their sovereign owners and can bring stability and growth to the economies the) invest in, concerns about the use of investments for political gains and about the defense of national security have led to calls for regulation of SWF investment worldwide. But rather than entangle these investments in a series of varied and complex domestic law solutions, this Comment argues that SWF investment can be effectively monitored through international arbitration. If SWFs are held accountable in international arbitration, they will increasingly behave as private investors and politically motivated investing will be more easily identified and prevented. The International Centre for Settlement of Investment Disputes (ICSID) provides just the forum for resolution of disputes regarding SWF investments. Through ICSID arbitration, international standards can be developed and enforced to protect commercially minded investing and to condemn politically motivated investing

The Design of a Morse-To-Teletype Signal Converter Using Intergrated Micrologic Circuitry.

This paper investigates the use of a Morse to teletype signal converter with existing teletype equipment to continuously monitor and display received Morse signals. This device would greatly reduce operator fatigue and provide increased efficiency. Important aspects of the converter design problem are presented and different approaches to the problems encountered in this design are developed. A micrologic digital design is presented and its operation discussed. Although not fully implemented, it is considered far superior to other methods of implementation. It will accept Morse keyed audio signals in the 300-3000 hz. range at keying speeds of 10 to 100 words per minute and convert them to teletype code.http://archive.org/details/thedesignofmorse1094540077Lieutenant, United States NavyApproved for public release; distribution is unlimited

Predictors of shoulder injuries in female collegiate swimmers

Competitive swimmers frequently injure their shoulders. The risk factors for shoulder injuries in competitive swimmers have not been clearly identified. The primary purposes of this study were to describe the characteristics of female collegiate swimmers at the onset of a swim season, identify the risk factors of shoulder injury in female collegiate swimmers, characterize the swim volume of female collegiate swimmers, and determine if swim volume is a predictor of shoulder injury. A prospective longitudinal cohort multi-center design was utilized. Female collegiate swimmers [n=53, mean age=19.3+/– 1.2] from four NCAA Division II universities were recruited to participate in this study. Preseason screening data that included demographics and sport history, swimming characteristics, and a musculoskeletal assessment was collected on 106 shoulders. Participants completed a weekly survey to track exposure data over the course of the season. Shoulder injury data was also collected. A shoulder injury was defined as swimming-related shoulder pain that resulted in one or more limited or modified athletic practices or competitions. Female swimmers reported a history of shoulder pain in 18/106 (17.0%) shoulders, and 14/106 (13.2%) of swimmers presented with obvious scapular dyskinesis at preseason. No differences in shoulder characteristics were found between swimmers with a history of shoulder pain and those without and those with obvious dyskinesis compared to those with normal scapular motion. There was a positive correlation between anterior glenohumeral laxity and shoulder external rotation range of motion (r=0.37, p Previous injury was the sole predictor of new shoulder injury in the group studied. Further research into the predictors of shoulder injury in female collegiate swimmers is warranted

Letter from J[oshua] B[ertram] Lippincott Co. to John Muir, 1910 Nov 8.

London 5, Henrietta Street, Covent GardenJ. B. Lippincott CompanyPublishers Washington SquarePhiladelphia November 8, 1910. Mr. John Muir, Martinez, Calif. Dear Sir:- We were so much interested by your sketch, Stickeen, that we are moved to ask if you have prepared anything of similar animal-human interest which might first be run in our Magazine and, perhaps, later in book form. Very truly yours, J. B. LIPPINCOTT COMPANY[illegible] 0489

Investigation of thermodynamic mechanisms for the production of complex compounds essential for the origin of life Final report, 1 Oct. 1965 - 30 Sep. 1966

Thermodynamic equilibria in planetary atmospheres and in origin of organic matter - determination of amino acid pairing and sequences in protein