Economic Impact of a Rotavirus Vaccine in Brazil

The study was done to evaluate the cost-effectiveness of a national rotavirus vaccination programme in Brazilian children from the healthcare system perspective. A hypothetical annual birth-cohort was followed for a five-year period. Published and national administrative data were incorporated into a model to quantify the consequences of vaccination versus no vaccination. Main outcome measures included the reduction in disease burden, lives saved, and disability-adjusted life-years (DALYs) averted. A rotavirus vaccinationprogramme in Brazil would prevent an estimated 1,804 deaths associated with gastroenteritis due to rotavirus, 91,127 hospitalizations, and 550,198 outpatient visits. Vaccination is likely to reduce 76% of the overall healthcare burden of rotavirus-associated gastroenteritis in Brazil. At a vaccine price of US$7-8 per dose, the cost-effectiveness ratio would be US$ 643 per DALY averted. Rotavirus vaccination can reduce the burden of gastroenteritis due to rotavirus at a reasonable cost-effectiveness ratio

Economic Impact of a Rotavirus Vaccine in Brazil

The study was done to evaluate the cost-effectiveness of a national rotavirus vaccination programme in Brazilian children from the healthcare system perspective. A hypothetical annual birth-cohort was followed for a five-year period. Published and national administrative data were incorporated into a model to quantify the consequences of vaccination versus no vaccination. Main outcome measures included the reduction in disease burden, lives saved, and disability-adjusted life-years (DALYs) averted. A rotavirus vaccinationprogramme in Brazil would prevent an estimated 1,804 deaths associated with gastroenteritis due to rotavirus, 91,127 hospitalizations, and 550,198 outpatient visits. Vaccination is likely to reduce 76% of the overall healthcare burden of rotavirus-associated gastroenteritis in Brazil. At a vaccine price of US$7-8 per dose, the cost-effectiveness ratio would be US$ 643 per DALY averted. Rotavirus vaccination can reduce the burden of gastroenteritis due to rotavirus at a reasonable cost-effectiveness ratio

Revision and cladistics of the Neotropical genus Pseudoptilolepis Snyder (Diptera, Muscidae) Revisão e cladística do gênero neotropical Pseudoptilolepis Snyder (Diptera, Muscidae)

Pseudoptilolepis Snyder, 1949, a monophyletic Neotropical muscid genus of six species, is reviewed to include four new species, P. centralis sp. nov., P. chrysella sp. nov., P. crocina sp. nov. and P. elbida sp. nov. A taxonomic key is provided for the genus. The phylogenetic relationship among the studied species is: (P. centralis ((P. chrysella (P. fluminensis, P. fulvapoda)) (P. nudapleura (P. elbida (P. nigripoda, P. crocina))))). The geographic distribution of the species is also presented and briefly discussed.<br>O gênero Neotropical monofilético Pseudoptilolepis Snyder, 1949 é revisado para a inclusão de quatro espécies novas, P. centralis sp. nov., P. chrysella sp. nov., P. crocina sp. nov. and P. elbida sp. nov. Uma chave taxonômica para o gênero é fornecida. A relação filogenética entre as espécies estudadas é: (P. centralis ((P. chrysella (P. fluminensis, P. fulvapoda)) (P. nudapleura (P. elbida (P. nigripoda, P. crocina))))). A distribuição geográfica das espécies é também apresentada e brevemente discutida