11,864 research outputs found

    Charged rotating noncommutative black holes

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    In this paper we complete the program of the noncomutative geometry inspired black holes, providing the richest possible solution, endowed with mass, charge and angular momentum. After providing a prescription for employing the Newman-Janis algorithm in the case of nonvanishing stress tensors, we find regular axisymmetric charged black holes in the presence of a minimal length. We study also the new thermodynamics and we determine the corresponding higher-dimensional solutions. As a conclusion we make some consideration about possible applications.Comment: 13 pages, 3 figures, correction of a typesetting inattention, updated reference list, version accepted for publication on Physical Review

    Induced pluripotent stem cells, a giant leap for mankind therapeutic applications

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    Induced pluripotent stem cells (iPSC) technology has propelled the field of stem cells biology, providing new cells to explore the molecular mechanisms of pluripotency, cancer biology and aging. A major advantage of human iPSC, compared to the pluripotent embryonic stem cells, is that they can be generated from virtually any embryonic or adult somatic cell type without destruction of human blastocysts. In addition, iPSC can be generated from somatic cells harvested from normal individuals or patients, and used as a cellular tool to unravel mechanisms of human development and to model diseases in a manner not possible before. Besides these fundamental aspects of human biology and physiology that are revealed using iPSC or iPSC-derived cells, these cells hold an immense potential for cell-based therapies, and for the discovery of new or personalized pharmacological treatments for many disorders. Here, we review some of the current challenges and concerns about iPSC technology. We introduce the potential held by iPSC for research and development of novel health-related applications. We briefly present the efforts made by the scientific and clinical communities to create the necessary guidelines and regulations to achieve the highest quality standards in the procedures for iPSC generation, characterization and long-term preservation. Finally, we present some of the audacious and pioneer clinical trials in progress with iPSC-derived cells.info:eu-repo/semantics/publishedVersio

    Spectral dimension of a quantum universe

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    In this paper, we calculate in a transparent way the spectral dimension of a quantum spacetime, considering a diffusion process propagating on a fluctuating manifold. To describe the erratic path of the diffusion, we implement a minimal length by averaging the graininess of the quantum manifold in the flat space case. As a result we obtain that, for large diffusion times, the quantum spacetime behaves like a smooth differential manifold of discrete dimension. On the other hand, for smaller diffusion times, the spacetime looks like a fractal surface with a reduced effective dimension. For the specific case in which the diffusion time has the size of the minimal length, the spacetime turns out to have a spectral dimension equal to 2, suggesting a possible renormalizable character of gravity in this regime. For smaller diffusion times, the spectral dimension approaches zero, making any physical interpretation less reliable in this extreme regime. We extend our result to the presence of a background field and curvature. We show that in this case the spectral dimension has a more complicated relation with the diffusion time, and conclusions about the renormalizable character of gravity become less straightforward with respect to what we found with the flat space analysis.Comment: 5 pages, 1 figure, references added, typos corrected, title changed, final version published in Physical Review

    Decoherence induced by a chaotic environment: A quantum walker with a complex coin

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    We study the differences between the process of decoherence induced by chaotic and regular environments. For this we analyze a family of simple models wich contain both regular and chaotic environments. In all cases the system of interest is a "quantum walker", i.e. a quantum particle that can move on a lattice with a finite number of sites. The walker interacts with an environment wich has a D dimensional Hilbert space. The results we obtain suggest that regular and chaotic environments are not distinguishable from each other in a (short) timescale t*, wich scales with the dimensionality of the environment as t*~log(D). Howeber, chaotic environments continue to be effective over exponentially longer timescales while regular environments tend to reach saturation much sooner. We present both numerical and analytical results supporting this conclusion. The family of chaotic evolutions we consider includes the so-called quantum multi-baker-map as a particular case.Comment: 7 pages, 8 figure

    Long wavelength structural anomalies in jammed systems

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    The structural properties of static, jammed packings of monodisperse spheres in the vicinity of the jamming transition are investigated using large-scale computer simulations. At small wavenumber kk, we argue that the anomalous behavior in the static structure factor, S(k)kS(k) \sim k, is consequential of an excess of low-frequency, collective excitations seen in the vibrational spectrum. This anomalous feature becomes more pronounced closest to the jamming transition, such that S(0)0S(0) \to 0 at the transition point. We introduce an appropriate dispersion relation that accounts for these phenomena that leads us to relate these structural features to characteristic length scales associated with the low-frequency vibrational modes of these systems. When the particles are frictional, this anomalous behavior is suppressed providing yet more evidence that jamming transitions of frictional spheres lie at lower packing fractions that that for frictionless spheres. These results suggest that the mechanical properties of jammed and glassy media may therefore be inferred from measurements of both the static and dynamical structure factors.Comment: 8 pages, 6 figure captions. Completely revised version to appear in Phys. Rev.

    Rheology and Contact Lifetime Distribution in Dense Granular Flows

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    We study the rheology and distribution of interparticle contact lifetimes for gravity-driven, dense granular flows of non-cohesive particles down an inclined plane using large-scale, three dimensional, granular dynamics simulations. Rather than observing a large number of long-lived contacts as might be expected for dense flows, brief binary collisions predominate. In the hard particle limit, the rheology conforms to Bagnold scaling, where the shear stress is quadratic in the strain rate. As the particles are made softer, however, we find significant deviations from Bagnold rheology; the material flows more like a viscous fluid. We attribute this change in the collective rheology of the material to subtle changes in the contact lifetime distribution involving the increasing lifetime and number of the long-lived contacts in the softer particle systems.Comment: 4 page

    invariant convex sets in polar representations

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    We study a compact invariant convex set E in a polar representation of a compact Lie group. Polar rapresentations are given by the adjoint action of K on p, where K is a maximal compact subgroup of a real semisimple Lie group G with Lie algebra g=k⊕p. If a⊂p is a maximal abelian subalgebra, then P=E∩a is a convex set in a. We prove that up to conjugacy the face structure of E is completely determined by that of P and that a face of E is exposed if and only if the corresponding face of P is exposed. We apply these results to the convex hull of the image of a restricted momentum map

    Parametric Amplification in the Dynamic Radiation Force of Acoustic Waves in Fluids

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    We report on parametric amplification in dynamic radiation force produced by a bichromatic acoustic beam in a fluid. To explain this effect we develop a theory taking into account the nonlinearity of the fluid. The theory is validated through an experiment to measure the dynamic radiation force on an acrylic sphere. Results exhibit an amplification of 66 dB in water and 80 dB in alcohol as the difference of the frequencies is increased from 10 Hz to 240 kHz

    Signals of Warped Extra Dimensions at the LHC

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    We discuss the signatures of the spin-2 graviton excitations predicted by the Randall-Sundrum model with one warped extra dimension, in dilepton and diphoton production at LHC. By using a specific angular analysis, we assess the ranges in mass and coupling constant where such gravitons can be discriminated against competitor spin-1 and spin-0 objects, that potentially could manifest themselves in these processes with the same mass and rate of events. Depending on the value of the coupling constant to quarks and leptons, the numerical results indicate graviton identification mass ranges up to 1.1-2.4 TeV and 1.6-3.2 TeV for LHC nominal energy of 14 TeV and time-integrated luminosity of 10 and 100~fb1{\rm fb}^{-1}, respectively.Comment: 8 pages, Talk given at QCD@Work - International Workshop on QCD - Theory and Experiment, 20 - 23 June, 2010, Martina Franca Ital
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