80 research outputs found

    Les programmes de formation initiale (FI) Ă  l’enseignement : Bilan des rĂ©formes rĂ©centes et nouvelles tendances pour une formation professionnelle efficace

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    La question directrice qui oriente cette Ă©tude est la suivante : Dans l’état actuel de nos connaissances et compte tenu de l’expĂ©rience accumulĂ©e aprĂšs plus d’une dĂ©cennie de rĂ©formes de la formation des maĂźtres en AmĂ©rique du Nord, comment concevoir et mettre en pratique dans les facultĂ©s et/ou les dĂ©partements d’éducation des programmes de formation initiale des enseignants qui soient pleinement adaptĂ©s aux besoins et rĂ©alitĂ©s du travail enseignant en milieu scolaire, et, par consĂ©quent, aux rĂŽles et compĂ©tences exigĂ©s aujourd’hui des praticiens de l’enseignement des niveaux primaire et secondaire

    Field Measurements of Terrestrial and Martian Dust Devils

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    Surface-based measurements of terrestrial and martian dust devils/convective vortices provided from mobile and stationary platforms are discussed. Imaging of terrestrial dust devils has quantified their rotational and vertical wind speeds, translation speeds, dimensions, dust load, and frequency of occurrence. Imaging of martian dust devils has provided translation speeds and constraints on dimensions, but only limited constraints on vertical motion within a vortex. The longer mission durations on Mars afforded by long operating robotic landers and rovers have provided statistical quantification of vortex occurrence (time-of-sol, and recently seasonal) that has until recently not been a primary outcome of more temporally limited terrestrial dust devil measurement campaigns. Terrestrial measurement campaigns have included a more extensive range of measured vortex parameters (pressure, wind, morphology, etc.) than have martian opportunities, with electric field and direct measure of dust abundance not yet obtained on Mars. No martian robotic mission has yet provided contemporaneous high frequency wind and pressure measurements. Comparison of measured terrestrial and martian dust devil characteristics suggests that martian dust devils are larger and possess faster maximum rotational wind speeds, that the absolute magnitude of the pressure deficit within a terrestrial dust devil is an order of magnitude greater than a martian dust devil, and that the time-of-day variation in vortex frequency is similar. Recent terrestrial investigations have demonstrated the presence of diagnostic dust devil signals within seismic and infrasound measurements; an upcoming Mars robotic mission will obtain similar measurement types

    Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2

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    Viral protein R (Vpr), an apoptogenic accessory protein encoded by HIV-1, induces mitochondrial membrane permeabilization (MMP) via a specific interaction with the permeability transition pore complex, which comprises the voltage-dependent anion channel (VDAC) in the outer membrane (OM) and the adenine nucleotide translocator (ANT) in the inner membrane. Here, we demonstrate that a synthetic Vpr-derived peptide (Vpr52-96) specifically binds to the intermembrane face of the ANT with an affinity in the nanomolar range. Taking advantage of this specific interaction, we determined the role of ANT in the control of MMP. In planar lipid bilayers, Vpr52-96 and purified ANT cooperatively form large conductance channels. This cooperative channel formation relies on a direct protein–protein interaction since it is abolished by the addition of a peptide corresponding to the Vpr binding site of ANT. When added to isolated mitochondria, Vpr52-96 uncouples the respiratory chain and induces a rapid inner MMP to protons and NADH. This inner MMP precedes outer MMP to cytochrome c. Vpr52-96–induced matrix swelling and inner MMP both are prevented by preincubation of purified mitochondria with recombinant Bcl-2 protein. In contrast to König's polyanion (PA10), a specific inhibitor of the VDAC, Bcl-2 fails to prevent Vpr52-96 from crossing the mitochondrial OM. Rather, Bcl-2 reduces the ANT–Vpr interaction, as determined by affinity purification and plasmon resonance studies. Concomitantly, Bcl-2 suppresses channel formation by the ANT–Vpr complex in synthetic membranes. In conclusion, both Vpr and Bcl-2 modulate MMP through a direct interaction with ANT

    Genetic Structure, Nestmate Recognition and Behaviour of Two Cryptic Species of the Invasive Big-Headed Ant Pheidole megacephala

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    A History of Universalism: Conceptions of the Internationality of Science from the Enlightenment to the Cold War

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    That science is fundamentally universal has been proclaimed innumerable times. But the precise geographical meaning of this universality has changed historically. This article examines conceptions of scientific internationalism from the Enlightenment to the Cold War, and their varying relations to cosmopolitanism, nationalism, socialism, and 'the West'. These views are confronted with recent tendencies to cast science as a uniquely European product

    Recherches sur la castramĂ©tation romaine. Établissement, traduction et commentaires du texte du pseudo-Hygin, De munitionibus castrorum

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    Lenoir Maurice. Recherches sur la castramĂ©tation romaine. Établissement, traduction et commentaires du texte du pseudo-Hygin, De munitionibus castrorum. In: École pratique des hautes Ă©tudes. 4e section, Sciences historiques et philologiques. Annuaire 1975-1976. 1976. pp. 1071-1080

    De Kairouan Ă  Volubilis

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    Le rĂ©examen des Ă©vĂ©nements militaires et diplomatiques dans le Maghreb pendant la seconde moitiĂ© du VIIe siĂšcle de notre Ăšre permet de mieux apprĂ©cier le rĂŽle et l'importance de la tribu des Awraba et de son chef Kusayla. Cette tribu doit ĂȘtre assimilĂ©e aux Ouerbikai/Ouereis, connus par PtolĂ©mĂ©e, qu'il faut localiser pour l'Ă©poque romaine sur les pentes du Rif dominant le fleuve Ouerrha. H est lĂ©gitime de supposer que la tribu, qui contrĂŽlait ainsi un des grands itinĂ©raires entre la Tingitane et la CĂ©sarienne, ait ultĂ©rieurement connu une expansion qui l'amena Ă  dominer aussi bien l'Ouest algĂ©rien que le Maroc central. L'ancienne ville romaine de Volubilis Ă©tait certainement devenu le «centre de gravité» de cette tribu. La grande famille des Caecilii, qui domine la vie municipale de Volubilis depuis l'Ă©poque prĂ©-romaine et a prĂ©sidĂ© au dernier amĂ©nagement du fo- rum de la ville, y a cependant maintenu sa suprĂ©matie : le nom du chef des Awraba, Kusayla, probable dĂ©formation de Caecilius comme l'a montrĂ© Ch.-E. Dufourcq, en est un indice assez clair.Lenoir Maurice. De Kairouan Ă  Volubilis. In: «Alla Signorina». MĂ©langes offerts Ă  NoĂ«lle de La BlanchardiĂšre. Rome : École Française de Rome, 1995. pp. 207-224. (Publications de l'École française de Rome, 204

    Bosra (Syrie) : le camp de la légion IIIe Cyrénaïque

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    Lenoir Maurice. Bosra (Syrie) : le camp de la lĂ©gion IIIe CyrĂ©naĂŻque. In: MĂ©langes de l'École française de Rome. AntiquitĂ©, tome 113, n°1. 2001. AntiquitĂ©. pp. 547-551
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