8,425 research outputs found

    Perturbations to observed ambient neutral densities due to presence of an Orbiting Geophysical Observatory

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    Perturbations in density of ions and neutral particles in upper atmosphere due to OG

    Age-related increase of kynurenic acid in human cerebrospinal fluid-IgG and beta(2)-microglobulin changes

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    Kynurenic acid (KYNA) is an endogenous metabolite in the kynurenine pathway of tryptophan degradation and is an antagonist at the glycine site of the N-methyl-D-aspartate as well as at the alpha 7 nicotinic cholinergic receptors. In the brain tissue KYNA is synthesised from L-kynurenine by kynurenine aminotransferases (KAT) I and II. A host of immune mediators influence tryptophan degradation. In the present study, the levels of KYNA in cerebrospinal fluid (CSF) and serum in a group of human subjects aged between 25 and 74 years were determined by using a high performance liquid chromatography method. In CSF and serum KAT I and II activities were investigated by radioenzymatic assay, and the levels of β2-microglobulin, a marker for cellular immune activation, were determined by ELISA. The correlations between neurochemical and biological parameters were evaluated. Two subject groups with significantly different ages, i.e. 50 years, p < 0.001, showed statistically significantly different CSF KYNA levels, i.e. 2.84 ± 0.16 fmol/μl vs. 4.09 ± 0.14 fmol/μl, p < 0.001, respectively; but this difference was not seen in serum samples. Interestingly, KYNA is synthesised in CSF principally by KAT I and not KAT II, however no relationship was found between enzyme activity and ageing. A positive relationship between CSF KYNA levels and age of subjects indicates a 95% probability of elevated CSF KYNA with ageing (R = 0.6639, p = 0.0001). KYNA levels significantly correlated with IgG and β2-microglobulin levels (R = 0.5244, p = 0.0049; R = 0.4253, p = 0.043, respectively). No correlation was found between other biological parameters in CSF or serum. In summary, a positive relationship between the CSF KYNA level and ageing was found, and the data would suggest age-dependent increase of kynurenine metabolism in the CNS. An enhancement of CSF IgG and β2-microglobulin levels would suggest an activation of the immune system during ageing. Increased KYNA metabolism may be involved in the hypofunction of the glutamatergic and/or nicotinic cholinergic neurotransmission in the ageing CNS

    Bounds on the electromagnetic interactions of excited spin-3/2 leptons

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    We discuss possible deviations from QED produced by a virtual excited spin-3/2 lepton in the reaction e+e2γe^+e^- \longrightarrow 2\gamma. Data recorded by the OPAL Collaboration at a c.m. energy s=183GeV\sqrt{s} = 183 GeV are used to establish bounds on the nonstandard-lepton mass and coupling strengths.Comment: Latex, 5 pages, 7 ps figures. To be published in Phys. Rev.

    Efeito da irrigação no crescimento de plantas de seringueira em viveiro.

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    Durante tres anos (1981-1983) foi conduzido, em viveiro, na Estacao Experimental do CNPSD, em Manaus-AM, um estudo objetivando avaliar os efeitos da irrigacao e da interacao irrigacao x fertilizantes sobre a altura e diametro de caule da seringueira (Hevea spp.). O delineamento experimental utilizado foi o de blocos ao acaso em esquema fatorial, contendo os seguintes tratamentos: irrigado/adubado (IA), irrigado/nao adubado (INA), nao irrigado/adubado (NIA) e nao irrigado/nao adubado (NINA). Nos tratamentos irrigados, o solo foi abastecido ate a capacidade de campo, a profundidade de 25 cm, toda vez que o potencial matricial por metro atingia -0,5 bar, ao passo que, nos adubados, uma mistura de NPKMg foi parcelada em cinco aplicacoes a cada 30 dias, sendo a primeira efetuada aos 60 dias apos o plantio. Nos dois primeiros anos analisados, verificou-se que os tratamentos irrigados foram significativamente superiores aos nao irrigados, particularmente quando a irrigacao esteve associada a adubacao. Em geral, o comportamenteo das diferentes praticas testadas apresentaram a seguinte ordem decrescente: IA>INA>NIA>NINA. Nao foi observada interacao dos efeitos principais (irrigacao x adubacao)

    Modélisation de l'évolution thermique saisonnière du lac du Bourget

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    Le lac du Bourget, l'un des principaux lacs alpins situé en France, a fait l'objet en 1981 d'importants travaux d'aménagement en vue de ta restauration de la qualité de ses eaux. Une campagne de mesure portant sur les années 1988-89 a été mise en place afin de faire le point sur l'évolution du lac depuis la fin des travaux.Un modèle thermique et biogéochimique (phosphore, oxygène, azote) sera utilisé pour synthétiser les connaissances, prévoir l'évolution de la qualité des eaux du lac ainsi que l'influence d'éventuels aménagements complémentaires. Les résultats présentés ici concernent la première étape du projet d'études, la modélisation thermique du lac du Bourget.Le modèle utilisé est un modèle unidimensionnel, vertical, basé sur l'équation d'advection-diffusion.L'expression des coefficients de dispersion selon la profondeur reprend celle d'un modèle du lac Léman (Tassin, 1986). Les équations utilisées distinguent l'épilimnion, le métalimnion et l'hypolimnion.Les résultats présentés montrent que le modèle décrit de façon satisfaisante le cycle thermique annuel et l'évolution inter-annuelle des températures dans le lac du Bourget.Les profils et les valeurs des coefficients de dispersion calculés sur le lac du Bourget sont proches de ceux obtenus sur d'autres lacs à partir de mesures fines de température ou de concentrations d'isotopes naturels.Les coefficients de dispersion obtenus pourront donc être utilisés dans la modélisation des substances dissoutes dans le lac.In 1981, important works including the diversion of the main sewers entering Lake Bourget (one of the largest French alpine lakes) were undertaken in order to restore acceptable water quality standards. A detailed water quality survey will be performed in 1988-89 to complete the data base which already covers ten years. It should help in quantifying the evolution of the lake since the 1981 restoration works. The following activities will be undertaken as part of the survey : measurements within the water column, a study of the bottom sediments, the setting-up of sediment traps and the coupling of Landsat satellite images with measurements performed at some stations at the lake surface. A thermal and biogeochemical (phosphorus, oxygen, nitrogen) model will be used to summarise the information available and to forecast the evolution of water quality and the effect of other restoration measures. This paper reports on the first part of the study : the thermal modelling of Lake Bourget. A one-dimensional, vertical model based on the advection-diffusion equation is used. This equation is solved using a finite difference, semi-implicit method. The resolution grid has 145 layers (1 meter high) and the time step is 3 hours.The heat fluxes at the air-water interface are computed with the three-hourly meteorological data collected at the Chambéry airport station, at the south end of the lake. The formulas are empirical and well established in the literature.The expression for the eddy diffusion coefficients is based on a model of the lake of Geneva (Tassin, 1986). Different equations are used for the epilimnion, metalimnion and hypolimnion. In the epilimnion, the eddy diffusion coefficient expresses, by the Richardson gradients number, the interaction between the shear stress of the wind and the water column stability. It depends on the value of the eddy diffusion in neutral conditions and on a stability function which includes the Richardson number. The vertical profile of the horizontal number. The vertical profile of the horizontal currents is computed following Ekman (1905) and Simons (1981) and is approximated by a gradient which decays exponentially.In the metalimnion and the hypolimnion, the water layer stability is characterised by the Brünt-Väisälä frequency. In the hypolimnion, the eddy diffusion coefficient includes a corrective term, which is a function of depth; this term serves to reduce the dispersion near the bottom of the lake.The thermal model also includes the mixing of the first layers by waves, the vertical advective transport induced by rivers inflows into the lake and by surface water withdrawal, as well as the thermal convection induced by local instabilities of the water column.The eight parameters occurring in the heat flux equations and the eddy diffusion coefficients were estimated using data from 1981. The model has been validated over an 8 years period 1976-1983).Results of the model agree with the observed seasonal and long-term evolutions of temperature in Lake Bourget. The main characteristics of the annual cycle are reproduced : set-up of the thermocline in spring, depth of the epilimnion, thermocline and metalimnion, value of the temperature gradient in the metalimnion, deepening of the thermocline in fall and winter overturn. Significant differences between observed and simulated temperatures occur in the metalimnion and they may be partially explained by internal waves which are dominant features at this level during summer stratification. This kind of mechanism cannot be accounted for in a one-dimensional vertical model.Profiles and values of eddy diffusion coefficients calculated for Lake Bourget show a good agreement with those obtained in other large takes from measurements of temperature or natural isotopes concentrations.In general, the thermal model gives a good account of heat transport mechanisms in Lake Bourget. Accordingly, it provides acceptable dispersion coefficients which can be used to model the distribution of dissolved species in the lake

    The OGO-2 neutral and ion mass spectrometer experiment

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    Statistical analysis of neutral and ion mass spectroscopy data for OGO-

    Effects of Different Number of Sets of Resistance Training on Flexibility

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    International Journal of Exercise Science 10(3): 354-364, 2017. The aim of this study was to investigate the effects of six months of training with three different number of sets of resistance training on flexibility in young men. Forty-seven men (mean ± SD age = 24 ± 1yrs; body mass = 79.39 ± 9.12 kg; height = 174.5 ± 5.6 cm) were randomly divided into three training groups performing either one set (G1S), three sets (G3S), or five sets (G5S) of all exercises in a resistance training session or a control group (CG). All groups were assessed pre- and post-training for Sit-and-Reach test and range of motion of 10 joints using goniometry. The training protocol included three weekly sessions and was composed of nine exercises performed at a moderate intensity (eight to 12RM). The results demonstrated significant differences pre- to post-training for the Sit-and-Reach test for all training groups; however, only the G5S showed significant differences when compared to the CG (31.04 ± 5.94cm vs. 23.56 ± 6.76cm, respectively; p \u3c 0.05). Of the ten joint movements measured, there were range of motion increases only to shoulder flexion (G1S), shoulder extension (G3S), elbow flexion (G3S), and knee flexion (G3S) when comparing pre- to post-training (p \u3c 0.05). In conclusion, different resistance training volumes improved flexibility for some joints of young men. These findings indicate that performing only resistance training can result in increases in flexibility

    Avaliação agronômica de acessos do banco ativo de germoplasma de cebola da Embrapa Clima Temperado em sistema convencional e orgânico de cultivo.

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    Objetivou-se avaliar o desempenho de oito acessos do banco ativo de germoplasma de cebola (Allium cepa) da Embrapa Clima Temperado nos sistemas orgânico e convencional de cultivo, em Pelotas-RS, na safra 2013/2014

    Concentração e época de aplicação de AminoetoxiVinilGlicine (AVG) na maturação de macieiras 'Fuji Suprema'.

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