628 research outputs found
Optimum size of a molecular bond cluster in adhesion
The strength of a bonded interface is considered for the case in which bonding is the result of clusters of discrete bonds distributed along the interface. Assumptions appropriate for the case of adhesion of biological cells to an extracellular matrix are introduced as a basis for the discussion. It is observed that those individual bonds nearest to the edges of a cluster are necessarily subjected to disproportionately large forces in transmitting loads across the interface, in analogy with well-known behavior in elastic crack mechanics. Adopting Bell's model for the kinetics of bond response under force, a stochastic model leading to a dependence of interface strength on cluster size is developed and analyzed. On the basis of this model, it is demonstrated that there is an optimum cluster size for maximum strength. This size arises from the competition between the nonuniform force distribution among bonds, which tends to promote smaller clusters, and stochastic response allowing bond reformation, which tends to promote larger clusters. The model results have been confirmed by means of direct Monte Carlo simulations. This analysis may be relevant to the observation that mature focal adhesion zones in cell bonding are found to have a relatively uniform size. © 2008 The American Physical Society.published_or_final_versio
Concurrent factors determine toughening in the hydraulic fracture of poroelastic composites
Brittle materials fail catastrophically. In consequence of their limited flaw-tolerance, failure occurs by localized fracture and is typically a dynamic process. Recently, experiments on epithelial cell monolayers have revealed that this scenario can be significantly modified when the material susceptible to cracking is adhered to a hydrogel substrate. Thanks to the hydraulic coupling between the brittle layer and the poroelastic substrate, such a composite can develop a toughening mechanism that relies on the simultaneous growth of multiple cracks. Here, we study this remarkable behaviour by means of a detailed model, and explore how the material and loading parameters concur in determining the macroscopic toughness of the system. By extending a previous study, our results show that rapid loading conveys material toughness by promoting distributed cracking. Moreover, our theoretical findings may suggest innovative architectures of flaw-insensitive materials with higher toughness. ArXI
Mechanical theory of the film-on-substrate-foil structure : curvature and overlay alignment in amorphous silicon thin-film devices fabricated on free-standing foil substrates
Flexible electronics will have inorganic devices grown at elevated temperatures on free-standing foil substrates. The thermal contraction mismatch between the substrate and the deposited device films, and the built-in stresses in these films, cause curving and a change in the in-plane dimensions of the workpiece. This change causes misalignment between the device layers. The thinner and more compliant the substrate, the larger the curvature and the misalignment. We model this situation with the theory of a bimetallic strip, which suggests that the misalignment can be minimized by tailoring the built-in stress introduced during film growth. Amorphous silicon thin-film transistors (a-Si:H TFTs) fabricated on stainless steel or polyimide (PI) (Kapton E®) foils need tensile built-in stress to compensate for the differential thermal contraction between the silicon films and the substrate. Experiments show that by varying the built-in stress in just one device layer, the gate silicon nitride (SiNx), one can reduce the misalignment between the source/drain and the gate levels from ∼400 parts-per-million to ∼100 parts-per-million
Acoustic Emission from a Crack Growth Event
Acoustic emission is a nondestructive testing technique that detects the stress wave emissions from deformation and fracture processes within a loaded structure; these signals are the result of various processes that occur within the body. Some potential sources of acoustic emission include: crack propagation and arrest, fretting between fracture surfaces, dislocation movement, microcracking, twinning and phase transformations. In addition to these failure related mechanisms, other phenomena such as fastener and joint fretting, structural vibration, cavitation, and electromagnetic noise can create signals which are picked up by acoustic emission instrumentation. The ability to isolate crack growth signals from other events would greatly enhance the current acoustic emission signal processing capability
Theory of dynamic crack branching in brittle materials
The problem of dynamic symmetric branching of an initial single brittle crack
propagating at a given speed under plane loading conditions is studied within a
continuum mechanics approach. Griffith's energy criterion and the principle of
local symmetry are used to determine the cracks paths. The bifurcation is
predicted at a given critical speed and at a specific branching angle: both
correlated very well with experiments. The curvature of the subsequent branches
is also studied: the sign of , with being the non singular stress at the
initial crack tip, separates branches paths that diverge from or converge to
the initial path, a feature that may be tested in future experiments. The model
rests on a scenario of crack branching with some reasonable assumptions based
on general considerations and in exact dynamic results for anti-plane
branching. It is argued that it is possible to use a static analysis of the
crack bifurcation for plane loading as a good approximation to the dynamical
case. The results are interesting since they explain within a continuum
mechanics approach the main features of the branching instabilities of fast
cracks in brittle materials, i.e. critical speeds, branching angle and the
geometry of subsequent branches paths.Comment: 41 pages, 15 figures. Accepted to International Journal of Fractur
Crack-Like Processes Governing the Onset of Frictional Slip
We perform real-time measurements of the net contact area between two blocks
of like material at the onset of frictional slip. We show that the process of
interface detachment, which immediately precedes the inception of frictional
sliding, is governed by three different types of detachment fronts. These
crack-like detachment fronts differ by both their propagation velocities and by
the amount of net contact surface reduction caused by their passage. The most
rapid fronts propagate at intersonic velocities but generate a negligible
reduction in contact area across the interface. Sub-Rayleigh fronts are
crack-like modes which propagate at velocities up to the Rayleigh wave speed,
VR, and give rise to an approximate 10% reduction in net contact area. The most
efficient contact area reduction (~20%) is precipitated by the passage of slow
detachment fronts. These fronts propagate at anomalously slow velocities, which
are over an order of magnitude lower than VR yet orders of magnitude higher
than other characteristic velocity scales such as either slip or loading
velocities. Slow fronts are generated, in conjunction with intersonic fronts,
by the sudden arrest of sub-Rayleigh fronts. No overall sliding of the
interface occurs until either of the slower two fronts traverses the entire
interface, and motion at the leading edge of the interface is initiated. Slip
at the trailing edge of the interface accompanies the motion of both the slow
and sub-Rayleigh fronts. We might expect these modes to be important in both
fault nucleation and earthquake dynamics.Comment: 19 page, 5 figures, to appear in International Journal of Fractur
Damage of woven composite under tensile and shear stress using infrared thermography and micrographic cuts
Infrared thermography was used to study damage developing in woven fabrics. Two different experiments were performed, a ±45° tensile test and a rail shear test. These two different types of tests show different damage scenarios, even if the shear stress/strain curves are similar. The ±45° tension test shows matrix hardening and matrix cracking whereas the rail shear test shows only matrix hardening. The infrared thermography was used to perform an energy balance, which enabled the visualization of the portion of dissipated energy caused by matrix cracking. The results showed that when the resin is subjected to pure shear, a larger amount of energy is stored by the material, whereas when the resin is subjected to hydrostatic pressure, the main part of mechanical energy is dissipated as heat
Imaging-guided chest biopsies: techniques and clinical results
Background
This article aims to comprehensively describe indications, contraindications, technical aspects, diagnostic accuracy and complications of percutaneous lung biopsy.
Methods
Imaging-guided biopsy currently represents one of the predominant methods for obtaining tissue specimens in patients with lung nodules; in many cases treatment protocols are based on histological information; thus, biopsy is frequently performed, when technically feasible, or in case other techniques (such as bronchoscopy with lavage) are inconclusive.
Results
Although a coaxial system is suitable in any case, two categories of needles can be used: fine-needle aspiration biopsy (FNAB) and core-needle biopsy (CNB), with the latter demonstrated to have a slightly higher overall sensitivity, specificity and accuracy.
Conclusion
Percutaneous lung biopsy is a safe procedure even though a few complications are possible: pneumothorax, pulmonary haemorrhage and haemoptysis are common complications, while air embolism and seeding are rare, but potentially fatal complications
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