Traumatic and non-traumatic spinal cord lesions: an Italian comparison of neurological and functional outcomes

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Fundamental limits of repeaterless quantum communications

Quantum communications promises reliable transmission of quantum information, efficient distribution of entanglement and generation of completely secure keys. For all these tasks, we need to determine the optimal point-to-point rates that are achievable by two remote parties at the ends of a quantum channel, without restrictions on their local operations and classical communication, which can be unlimited and two-way. These two-way assisted capacities represent the ultimate rates that are reachable without quantum repeaters. Here, by constructing an upper bound based on the relative entropy of entanglement and devising a dimension-independent technique dubbed ‘teleportation stretching’, we establish these capacities for many fundamental channels, namely bosonic lossy channels, quantum-limited amplifiers, dephasing and erasure channels in arbitrary dimension. In particular, we exactly determine the fundamental rate-loss tradeoff affecting any protocol of quantum key distribution. Our findings set the limits of point-to-point quantum communications and provide precise and general benchmarks for quantum repeaters

Il progetto “ceraNEApolis”: un sistema informativo cartografico delle produzioni ceramiche a Neapolis (IV a.C.-VII d.C.)

In the last few decades, urban archaeology in Naples has contributed to outline the history of the city. The discovery of a great amount of pottery gave information about the daily life of ancient Naples. It was therefore decided to draw up a thematic archaeological map of the ceramics finds to reconstruct their production and distribution from the 4th century B.C. to the 7th century A.D. The project ceraNEApolis consists of a pottery map linked to a bibliographic database, which will be made available online: a working tool for experts, useful to outline the cultural city stratification and to understand the Neapolitan archaeological sites through the material. It is useful in defining the topography of production (workshop, raw materials, and resources), distribution (communication routes, harbour, market), uses and consumption patterns (house, habitat, sacred areas, burials) in the city, even if lacking monumental evidence. It contributes to the reconstruction and analysis of the cultural and urban landscape, taking into account the geomorphological elements and the data contexts even in diachronic and transversal multi-disciplinary perspective. The analysis of some significant cases shows its validity also for potential alternative fruition. The integration of virtual reality systems is a possible extension also for the knowledge, enhancement, communication and use of cultural heritage

A retrospective, multicentre study of perampanel given as monotherapy in routine clinical care in people with epilepsy

PURPOSE: Perampanel is approved for adjunctive treatment of focal seizures, with or without secondarily generalised seizures, and for primary generalised tonic-clonic seizures in people with epilepsy aged ≥12 years. Perampanel was recently approved for monotherapy use for partial seizures in the United States. This study provides insight into the feasibility of perampanel monotherapy in real-world settings. METHODS: This retrospective, non-interventional, multicentre study (NCT02736162) was conducted between January 2013 and March 2016 in specialist epilepsy centres in Europe and Russia. Eligible individuals had a diagnosis of epilepsy and received perampanel primary or secondary monotherapy as routine clinical care. The primary endpoint was proportion of individuals remaining on perampanel monotherapy, after conversion from perampanel adjunctive treatment, at 3, 6, 12, 18 and 24 months (retention rate). RESULTS: Sixty individuals were in the safety set (female, 63%; white, 97%; aged 18 to <65 years, 73%). Most (85%) received secondary monotherapy with perampanel. At study cut-off, 68% of individuals were continuing on perampanel monotherapy (secondary monotherapy: 55%). The median duration of retention was not calculable due to the high number of individuals ongoing on monotherapy. Twelve individuals had treatment-emergent adverse events that started during perampanel monotherapy, the most frequent was dizziness (5%). One serious treatment-emergent adverse event was reported (pneumonia during adjunctive perampanel treatment). CONCLUSIONS: In this small retrospective study of individuals who received perampanel monotherapy, the majority maintained monotherapy. Perampanel monotherapy may be an achievable option in some people with epilepsy

Galactic cosmic-ray flux short-term variations and associated interplanetary structures with LISA Pathfinder

The European Space Agency LISA Pathfinder (LPF) mission orbited around the Sun-Earth first Lagrangian point L1 between January 2016 and July 2017. A particle detector aboard LPF allowed for galactic cosmic-ray (GCR) integral flux measurements above 70 MeV n−1 between 2016 February 18 and 2017 July 3 during the descending phase of the present solar cycle N. 24, which is characterized by a positive polarity period. The statistical uncertainty on hourly-averaged GCR countings was of 1%. The characteristics of recurrent and non-recurrent GCR flux short-term variations observed with LPF are reported here. In particular, it is focused on GCR flux variation profiles and their association with the passage of large-scale interplanetary structures. Forbush decrease observations and geomagnetic storm occurrence during LPF are also briefly discussed

From the Sun to Earth: effects of the 25 August 2018 geomagnetic storm

Abstract. On 25 August 2018 the interplanetary counterpart of the 20 August 2018 coronal mass ejection (CME) hit Earth, giving rise to a strong G3 geomagnetic storm. We present a description of the whole sequence of events from the Sun to the ground as well as a detailed analysis of the observed effects on Earth's environment by using a multi-instrumental approach. We studied the ICME (interplanetary-CME) propagation in interplanetary space up to the analysis of its effects in the magnetosphere, ionosphere and at ground level. To accomplish this task, we used ground- and space-collected data, including data from CSES (China Seismo-Electric Satellite), launched on 11 February 2018. We found a direct connection between the ICME impact point on the magnetopause and the pattern of Earth's auroral electrojets. Using the Tsyganenko TS04 model prevision, we were able to correctly identify the principal magnetospheric current system activating during the different phases of the geomagnetic storm. Moreover, we analysed the space weather effects associated with the 25 August 2018 solar event in terms of the evaluation of geomagnetically induced currents (GICs) and identification of possible GPS (Global Positioning System) losses of lock. We found that, despite the strong geomagnetic storm, no loss of lock had been detected. On the contrary, the GIC hazard was found to be potentially more dangerous than other past, more powerful solar events, such as the 2015 St Patrick's Day geomagnetic storm, especially at latitudes higher than 60∘ in the European sector

Preface

Not abstract available

Recurrent flares in active region NOAA 11283

Context. Flares and coronal mass ejections (CMEs) are solar phenomena that are not yet fully understood. Several investigations have been performed to single out their related physical parameters that can be used as indices of the magnetic complexity leading to their occurrence. Aims. In order to shed light on the occurrence of recurrent flares and subsequent associated CMEs, we studied the active region NOAA 11283 where recurrent M and X GOES-class flares and CMEs occurred. Methods. We use vector magnetograms taken by HMI/SDO to calculate the horizontal velocity fields of the photospheric magnetic structures, the shear and the dip angles of the magnetic field, the magnetic helicity flux distribution, and the Poynting fluxes across the photosphere due to the emergence and the shearing of the magnetic field. Results. Although we do not observe consistent emerging magnetic flux through the photosphere during the observation time interval, we detected a monotonic increase of the magnetic helicity accumulated in the corona. We found that both the shear and the dip angles have high values along the main polarity inversion line (PIL) before and after all the events. We also note that before the main flare of X2.1 GOES class, the shearing motions seem to inject a more significant energy than the energy injected by the emergence of the magnetic field. Conclusions. We conclude that the very long duration (about 4 days) of the horizontal displacement of the main photospheric magnetic structures along the PIL has a primary role in the energy release during the recurrent flares. This peculiar horizontal velocity field also contributes to the monotonic injection of magnetic helicity into the corona. This process, coupled with the high shear and dip angles along the main PIL, appears to be responsible for the consecutive events of loss of equilibrium leading to the recurrent flares and CMEs

Solar Intensity X-Ray and Particle Spectrometer SIXS : Instrument Design and First Results

The Solar Intensity X-ray and particle Spectrometer (SIXS) on the BepiColombo Mercury Planetary Orbiter ("Bepi") measures the direct solar X-rays, energetic protons, and electrons that bombard, and interact with, the Hermean surface. The interactions result in X-ray fluorescence and scattering, and particle induced X-ray emission (PIXE), i.e. "glow" of the surface in X-rays. Simultaneous monitoring of the incident and emitted radiation enables derivation of the abundances of some chemical elements and scattering properties of the outermost surface layer of the planet, and it may reveal other sources of X-ray emission, due to, for example, weak aurora-like phenomena in Mercury's exosphere. Mapping of the Hermean X-ray emission is the main task of the MIXS instrument onboard BepiColombo. SIXS data will also be used for investigations of the solar X-ray corona and solar energetic particles (SEP), both in the cruise phase and the passes of the Earth, Venus and Mercury before the arrival at Mercury's orbit, and the final science phase at Mercury's orbit. These observations provide the first-ever opportunity for in-situ measurements of the propagation of SEPs, their interactions with the interplanetary magnetic field, and space weather phenomena in multiple locations throughout the inner solar system far away from the Earth, and more extensively at Mercury's orbit. In this paper we describe the scientific objectives, design and calibrations, operational principles, and scientific performance of the final SIXS instrument launched to the mission to planet Mercury onboard BepiColombo. We also provide the first analysis results of science observations with SIXS, that were made during the Near-Earth Commissioning Phase and early cruise phase operations in 2018-19, including the background X-ray sky observations and "first light" observations of the Sun with the SIXS X-ray detection system (SIXS-X), and in-situ energetic electron and proton observations with the SIXS Particle detection system (SIXS-P).Peer reviewe