28,574 research outputs found
0.75 atoms improve the clock signal of 10,000 atoms
Since the pioneering work of Ramsey, atom interferometers are employed for
precision metrology, in particular to measure time and to realize the second.
In a classical interferometer, an ensemble of atoms is prepared in one of the
two input states, whereas the second one is left empty. In this case, the
vacuum noise restricts the precision of the interferometer to the standard
quantum limit (SQL). Here, we propose and experimentally demonstrate a novel
clock configuration that surpasses the SQL by squeezing the vacuum in the empty
input state. We create a squeezed vacuum state containing an average of 0.75
atoms to improve the clock sensitivity of 10,000 atoms by 2.05 dB. The SQL
poses a significant limitation for today's microwave fountain clocks, which
serve as the main time reference. We evaluate the major technical limitations
and challenges for devising a next generation of fountain clocks based on
atomic squeezed vacuum.Comment: 9 pages, 6 figure
Sulfited Tannin Capsules: Novel Stimuli-Responsive Delivery Systems
Microcapsules of sulfited Acacia mearnsii tannin (AmST-MCs) were generated for the first time via the sonochemical method. Their stability profile was assessed and set in the general context of tannin microcapsules (TMCs) generated under the same experimental conditions. The analytical data gathered in this work indicate an excellent stability of TMCs over time as well as under high temperature and pressure, which is a major milestone toward the meaningful applications of TMCs in industrial, pharmaceutical, and biomedical applications in which sterilization of TMCs might be a prerequisite. Active release is shown to be efficiently triggered by varying pH and/or salinity, with different profiles for TMCs from sulfited and nonsulfited species. Surfactants also affect the stability of TMCs significantly, with effects eventually amplifiable by pH and the inherent kosmotropic and chaotropic characteristics of salt components in solutions
An analytical toolbox for fast and straightforward structural characterisation of commercially available tannins
Both condensed and hydrolysable tannins represent versatile natural polyphenolic structures exhibiting a broad range of activities that could be exploited in various fields including nutraceutics, cosmesis, consumer care, household and pharmaceutical applications. Various tannins are commercially available nowadays for use in such application fields. We have analysed a representative selection of commercially available condensed and hydrolysable tannins for structural features and purity. Using a combination of quantitative31 P NMR spectroscopy, HSQC measurements, MALDI-ToF analyses, gel permeation chromatography and wet chemical analysis, detailed structural characterisations and descriptions were possible, allowing for verification and falsification of claimed structural features
Markov Chain Beam Randomization: a study of the impact of PLANCK beam measurement errors on cosmological parameter estimation
We introduce a new method to propagate uncertainties in the beam shapes used
to measure the cosmic microwave background to cosmological parameters
determined from those measurements. The method, which we call Markov Chain Beam
Randomization, MCBR, randomly samples from a set of templates or functions that
describe the beam uncertainties. The method is much faster than direct
numerical integration over systematic `nuisance' parameters, and is not
restricted to simple, idealized cases as is analytic marginalization. It does
not assume the data are normally distributed, and does not require Gaussian
priors on the specific systematic uncertainties. We show that MCBR properly
accounts for and provides the marginalized errors of the parameters. The method
can be generalized and used to propagate any systematic uncertainties for which
a set of templates is available. We apply the method to the Planck satellite,
and consider future experiments. Beam measurement errors should have a small
effect on cosmological parameters as long as the beam fitting is performed
after removal of 1/f noise.Comment: 17 pages, 23 figures, revised version with improved explanation of
the MCBR and overall wording. Accepted for publication in Astronomy and
Astrophysics (to appear in the Planck pre-launch special issue
Digital Availability of Product Information for Collaborative Engineering of Spacecraft
In this paper, we introduce a system to collect product information from
manufacturers and make it available in tools that are used for concurrent
design of spacecraft. The planning of a spacecraft needs experts from different
disciplines, like propulsion, power, and thermal. Since these different
disciplines rely on each other there is a high need for communication between
them, which is often realized by a Model-Based Systems Engineering (MBSE)
process and corresponding tools. We show by comparison that the product
information provided by manufacturers often does not match the information
needed by MBSE tools on a syntactic or semantic level. The information from
manufacturers is also currently not available in machine-readable formats.
Afterwards, we present a prototype of a system that makes product information
from manufacturers directly available in MBSE tools, in a machine-readable way.Comment: accepted at CDVE201
Quantum Correction in Exact Quantization Rules
An exact quantization rule for the Schr\"{o}dinger equation is presented. In
the exact quantization rule, in addition to , there is an integral term,
called the quantum correction. For the exactly solvable systems we find that
the quantum correction is an invariant, independent of the number of nodes in
the wave function. In those systems, the energy levels of all the bound states
can be easily calculated from the exact quantization rule and the solution for
the ground state, which can be obtained by solving the Riccati equation. With
this new method, we re-calculate the energy levels for the one-dimensional
systems with a finite square well, with the Morse potential, with the symmetric
and asymmetric Rosen-Morse potentials, and with the first and the second
P\"{o}schl-Teller potentials, for the harmonic oscillators both in one
dimension and in three dimensions, and for the hydrogen atom.Comment: 10 pages, no figure, Revte
Resolving Non-Determinism in Choreographies
Resolving non-deterministic choices of choreographies is a crucial task. We introduce a novel notion of realisability for choreographies âcalled whole-spectrum implementationâ that rules out deterministic implementations of roles that, no matter which context they are placed in, will never follow one of the branches of a non-deterministic choice. We show that, under some conditions, it is decidable whether an implementation is whole-spectrum. As a case study, we analyse the POP protocol under the lens of whole-spectrum implementation
Reversing quantum trajectories with analog feedback
We demonstrate the active suppression of transmon qubit dephasing induced by
dispersive measurement, using parametric amplification and analog feedback. By
real-time processing of the homodyne record, the feedback controller reverts
the stochastic quantum phase kick imparted by the measurement on the qubit. The
feedback operation matches a model of quantum trajectories with measurement
efficiency , consistent with the result obtained by
postselection. We overcome the bandwidth limitations of the amplification chain
by numerically optimizing the signal processing in the feedback loop and
provide a theoretical model explaining the optimization result.Comment: 5 pages, 4 figures, and Supplementary Information (7 figures
Apoptotic and chemotherapeutic properties of iron(III)-salophene in an ovarian cancer animal model
The cytotoxicity of organometallic compounds iron(III)-, cobalt(III)-, manganese(II)-, and copper(II)-salophene (-SP) on platinum-resistant ovarian cancer cell lines was compared. Fe-SP displayed selective cytotoxicity (IC 50 at âŒ1 ÎŒM) against SKOV-3 and OVCAR-3 cell lines while Co-SP caused cytotoxic effects only at higher concentrations (IC50 at 60 ?M) and Cu-SP effects were negligible. High cytotoxicity of Mn-SP (30-60 ÎŒM) appeared to be nonspecific because the Mn-chloride salt reduced cell viability similarly. The effect of Fe-SP at 1 ÎŒM proved to be ovarian cancer cell selective when compared to a panel of cell lines derived from different tumors. The first irreversible step in the induction of cell death by Fe-SP occurred after 3 hrs as indicated by the mitochondrial transmembrane potential (ÎΚm) and was mainly linked to apoptotic, not necrotic events. To evaluate the toxicity of Fe-SP in vivo we conducted an acute toxicity study in rats. The LD 50 of Fe-SP is >2000 mg/kg orally and >5.5 mg/kg body weight by intraperitoneal injection. An ovarian cancer animal model showed that the chemotherapeutic relevant dose of Fe-SP in rats is 0.5-1 mg/kg body weight. The present report suggests that Fe-SP is a potential therapeutic drug to treat ovarian cancer. © 2009 Lange et al, publisher and licensee Dove Medical Press Ltd
Satisfying the Einstein-Podolsky-Rosen criterion with massive particles
In 1935, Einstein, Podolsky and Rosen (EPR) questioned the completeness of
quantum mechanics by devising a quantum state of two massive particles with
maximally correlated space and momentum coordinates. The EPR criterion
qualifies such continuous-variable entangled states, where a measurement of one
subsystem seemingly allows for a prediction of the second subsystem beyond the
Heisenberg uncertainty relation. Up to now, continuous-variable EPR
correlations have only been created with photons, while the demonstration of
such strongly correlated states with massive particles is still outstanding.
Here, we report on the creation of an EPR-correlated two-mode squeezed state in
an ultracold atomic ensemble. The state shows an EPR entanglement parameter of
0.18(3), which is 2.4 standard deviations below the threshold 1/4 of the EPR
criterion. We also present a full tomographic reconstruction of the underlying
many-particle quantum state. The state presents a resource for tests of quantum
nonlocality and a wide variety of applications in the field of
continuous-variable quantum information and metrology.Comment: 8 pages, 7 figure
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