1,054 research outputs found
Phase-Controlled Force and Magnetization Oscillations in Superconducting Ballistic Nanowires
The emergence of superconductivity-induced phase-controlled forces in the
(0.01-0.1) nN range, and of magnetization oscillations, in nanowire junctions,
is discussed. A giant magnetic response to applied weak magnetic fields, is
predicted in the ballistic Josephson junction formed by a superconducting tip
and a surface, bridged by a normal metal nanowire where Andreev states form.Comment: 5 pages, 3 figure
Strongly correlated wave functions for artificial atoms and molecules
A method for constructing semianalytical strongly correlated wave functions
for single and molecular quantum dots is presented. It employs a two-step
approach of symmetry breaking at the Hartree-Fock level and of subsequent
restoration of total spin and angular momentum symmetries via Projection
Techniques. Illustrative applications are presented for the case of a
two-electron helium-like single quantum dot and a hydrogen-like quantum dot
molecule.Comment: 9 pages. Revtex with 2 GIF and 1 EPS figures. Published version with
extensive clarifications. A version of the manuscript with high quality
figures incorporated in the text is available at
http://calcite.physics.gatech.edu/~costas/qdhelproj.html For related papers,
see http://www.prism.gatech.edu/~ph274c
Which is more cost‐effective under the MELD system: primary liver transplantation, or salvage transplantation after hepatic resection or after loco‐regional therapy for hepatocellular carcinoma within Milan criteria?
AbstractObjectiveThe optimal strategy for treating hepatocellular carcinoma (HCC), a disease with increasing incidence, in patients with Child–Pugh class A cirrhosis has long been debated. This study evaluated the cost‐effectiveness of hepatic resection (HR) or locoregional therapy (LRT) followed by salvage orthotopic liver transplantation (SOLT) vs. that of primary orthotopic liver transplantation (POLT) for HCC within the Milan Criteria.MethodsA Markov‐based decision analytic model simulated outcomes, expressed in costs and quality‐adjusted life years (QALYs), for the three treatment strategies. Baseline parameters were determined from a literature review. Sensitivity analyses tested model strength and parameter variability.ResultsBoth HR and LRT followed by SOLT were associated with earlier recurrence, decreased survival, increased costs and decreased quality of life (QoL), whereas POLT resulted in decreased recurrence, increased survival, decreased costs and increased QoL. Specifically, HR/SOLT yielded 3.1QALYs (at US74000/QALY), whereas POLT yielded 5.5QALYs (at US$52000/QALY). Sensitivity analyses supported these findings at clinically meaningful probabilities.ConclusionsUnder the Model for End‐stage Liver Disease (MELD) system, in patients with HCC within the Milan Criteria, POLT increases survival and QoL at decreased costs compared with HR or LRT followed by SOLT. Therefore, POLT is the most cost‐effective strategy for the treatment of HCC
Which is more cost‐effective under the MELD system: primary liver transplantation, or salvage transplantation after hepatic resection or after loco‐regional therapy for hepatocellular carcinoma within Milan criteria?
AbstractObjectiveThe optimal strategy for treating hepatocellular carcinoma (HCC), a disease with increasing incidence, in patients with Child–Pugh class A cirrhosis has long been debated. This study evaluated the cost‐effectiveness of hepatic resection (HR) or locoregional therapy (LRT) followed by salvage orthotopic liver transplantation (SOLT) vs. that of primary orthotopic liver transplantation (POLT) for HCC within the Milan Criteria.MethodsA Markov‐based decision analytic model simulated outcomes, expressed in costs and quality‐adjusted life years (QALYs), for the three treatment strategies. Baseline parameters were determined from a literature review. Sensitivity analyses tested model strength and parameter variability.ResultsBoth HR and LRT followed by SOLT were associated with earlier recurrence, decreased survival, increased costs and decreased quality of life (QoL), whereas POLT resulted in decreased recurrence, increased survival, decreased costs and increased QoL. Specifically, HR/SOLT yielded 3.1QALYs (at US74000/QALY), whereas POLT yielded 5.5QALYs (at US$52000/QALY). Sensitivity analyses supported these findings at clinically meaningful probabilities.ConclusionsUnder the Model for End‐stage Liver Disease (MELD) system, in patients with HCC within the Milan Criteria, POLT increases survival and QoL at decreased costs compared with HR or LRT followed by SOLT. Therefore, POLT is the most cost‐effective strategy for the treatment of HCC
Premelting of Thin Wires
Recent work has raised considerable interest on the nature of thin metallic
wires. We have investigated the melting behavior of thin cylindrical Pb wires
with the axis along a (110) direction, using molecular dynamics and a
well-tested many-body potential. We find that---in analogy with cluster
melting---the melting temperature of a wire with radius is lower
than that of a bulk solid, , by . Surface melting
effects, with formation of a thin skin of highly diffusive atoms at the wire
surface, is observed. The diffusivity is lower where the wire surface has a
flat, local (111) orientation, and higher at (110) and (100) rounded areas. The
possible relevance to recent results on non-rupturing thin necks between an STM
tip and a warm surface is addressed.Comment: 10 pages, 4 postscript figures are appended, RevTeX, SISSA Ref.
131/94/CM/S
CHIANTI - an Atomic Database for Emission Lines. Paper VI: Proton Rates and Other Improvements
The CHIANTI atomic database contains atomic energy levels, wavelengths,
radiative transition probabilities and electron excitation data for a large
number of ions of astrophysical interest. Version 4 has been released, and
proton excitation data is now included, principally for ground configuration
levels that are close in energy. The fitting procedure for excitation data,
both electrons and protons, has been extended to allow 9 point spline fits in
addition to the previous 5 point spline fits. This allows higher quality fits
to data from close-coupling calculations where resonances can lead to
significant structure in the Maxwellian-averaged collision strengths. The
effects of photoexcitation and stimulated emission by a blackbody radiation
field in a spherical geometry on the level balance equations of the CHIANTI
ions can now be studied following modifications to the CHIANTI software. With
the addition of H I, He I and N I, the first neutral species have been added to
CHIANTI. Many updates to existing ion data-sets are described, while several
new ions have been added to the database, including Ar IV, Fe VI and Ni XXI.
The two-photon continuum is now included in the spectral synthesis routines,
and a new code for calculating the relativistic free-free continuum has been
added. The treatment of the free-bound continuum has also been updated.Comment: CHIANTI is available at http://wwwsolar.nrl.navy.mil/chianti.htm
Four electrons in a two-leg Hubbard ladder: exact ground states
In the case of a two-leg Hubbard ladder we present a procedure which allows
the exact deduction of the ground state for the four particle problem in
arbitrary large lattice system, in a tractable manner, which involves only a
reduced Hilbert space region containing the ground state. In the presented
case, the method leads to nine analytic, linear, and coupled equations
providing the ground state. The procedure which is applicable to few particle
problems and other systems as well is based on an r-space representation of the
wave functions and construction of symmetry adapted orthogonal basis wave
vectors describing the Hilbert space region containing the ground state. Once
the ground state is deduced, a complete quantum mechanical characterization of
the studied state can be given. Since the analytic structure of the ground
state becomes visible during the use of the method, its importance is not
reduced only to the understanding of theoretical aspects connected to exact
descriptions or potential numerical approximation scheme developments, but is
relevant as well for a large number of potential technological application
possibilities placed between nano-devices and quantum calculations, where the
few particle behavior and deep understanding are important key aspects to know.Comment: 19 pages, 5 figure
Dislocation Emission around Nanoindentations on a (001) fcc Metal Surface Studied by STM and Atomistic Simulations
We present a combined study by Scanning Tunneling Microscopy and atomistic
simulations of the emission of dissociated dislocation loops by nanoindentation
on a (001) fcc surface. The latter consist of two stacking-fault ribbons
bounded by Shockley partials and a stair-rod dislocation. These dissociated
loops, which intersect the surface, are shown to originate from loops of
interstitial character emitted along the directions and are usually
located at hundreds of angstroms away from the indentation point. Simulations
reproduce the nucleation and glide of these dislocation loops.Comment: 10 pages, 4 figure
Aharonov-Bohm effect and plasma oscillations in superconducting tubes and rings
Low frequency plasma oscillations in superconducting tubes are considered.
The emergence of two different dimensionality regimes of plasma oscillations in
tubes, exhibiting a crossover from one-dimensional to two-dimensional behavior,
depending on whether or , where is the plasmon wave
vector and is the radius of the tube, is discussed. The Aharonov-Bohm
effect pertaining to plasma oscillations in superconducting tubes and rings,
resulting in an oscillatory behavior of the plasmon frequency as a function of
the magnetic flux, with a flux quantum period (analog of the
Little-Parks effect), is studied. The amplitude of the oscillations is
proportional to , where is the superconducting coherence
length.Comment: 18 pages, 4 figure
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