14,584 research outputs found

    Harvesting the Twittersphere: Qualitative Research Methods Using Twitter

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    Harvesting the Twittersphere explores the current state of research, by comparing quantitative to qualitative and analyzing the current market. In a consumer driven market, it seems that most businesses are neglecting to perfomr qualitative research. It could be because of the falling cost and increasing convenience of quantitative research methods provided by cloud systems such as: Salesforce.com, IBM, SAP, and Mckinsey. Another reason may be that there is no efficient or inexpensive way to conduct qualitative research on a digital platform. While certain companies try to conduct qualitative studies online by using chat rooms, discussion boards or Facebook prompts, there is no method that is as widespread or respective as the traditional methods. While focus groups and participant observation offer unique insights into consumers, both methods can be costly and difficult to set up. Harvesting the Twittershpere proposes a new methodology of using Twitter to conduct a qualitative study . By searching a specific term, a researcher can search through a constantly generated tweets to see what people are saying about the term. The tweets should be captured, sorted and analyzed in order to proivde a unique insight from the consumer. By nature, Twitter offers feelings of users since what they tweet is usually their individual perspective on the subject. This is the perfect field in order to conduct a qualitative study since it is about sharing emotions, sentiments and feelings, rather than numbers, facts or statistics. The paper also presents an example of this methodology by conducting research on Spotify, a music streaming application. The case presents how collection, sorting, analysis and the report were conducted and prepared in order to gtive readers a deeper understanding of the type of insights that can be gained from this method

    BiplotGUI: Interactive Biplots in R

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    Biplots simultaneously provide information on both the samples and the variables of a data matrix in two- or three-dimensional representations. The BiplotGUI package provides a graphical user interface for the construction of, interaction with, and manipulation of biplots in R. The samples are represented as points, with coordinates determined either by the choice of biplot, principal coordinate analysis or multidimensional scaling. Various transformations and dissimilarity metrics are available. Information on the original variables is incorporated by linear or non-linear calibrated axes. Goodness-of-fit measures are provided. Additional descriptors can be superimposed, including convex hulls, alpha-bags, point densities and classification regions. Amongst the interactive features are dynamic variable value prediction, zooming and point and axis drag-and-drop. Output can easily be exported to the R workspace for further manipulation. Three-dimensional biplots are incorporated via the rgl package. The user requires almost no knowledge of R syntax.

    Study of contamination sensors. Volume I - Executive summary report

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    Design criteria for automatic remotely indicating fluid contamination sensors, monitors, counters, and recorders and for sampling equipment and technique

    For post-statist geographies

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    This article critically investigates past and contemporary treatments of the state within geographical scholarship. We propose that there is a silent statism within geography that has shaped it in ways that limit geographical imaginations. Statism, herein, refers to a pervasive, historically contingent organisational logic that valourises and naturalises sovereign, coercive, and hierarchical relationships, within and beyond state spaces. We argue that although the explicit, colonial statism that characterised early geography is past, traces of statism nonetheless underpin much of the discipline. While political geography has increasingly critiqued ‘state-centrism’, we argue that it is essential to move beyond critique alone. Using anarchist state theory to critically build upon perspectives in geography, we argue that statism is intellectually and politically problematic and should be recast as an active constituent of unequal social relations. In turn, we outline five core myths that form its logical foundations. In concluding, three initial areas in which post-statist geographies can make inroads are identified: interrogating intersections between statism and other power relations; constructing post-statist epistemologies and methodologies; and addressing how the state is represented in geographical work

    Obsidian Sourcing at Uliland Bundok Site and its Implications for Mobility, Exchange, and Social Contexts in the Philippine Metal Age

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    This article discusses the results of chemical analysis to trace the source of the obsidian artifacts from the site of Ulilang Bundok in Batangas, Philippines. The obsidian artifacts used in this study were excavated from the site of Ulilang Bundok while samples of obsidian were also collected from known obsidian sources in Nagcarlan, Batangas, and Pagudpod, Ilocos Norte, for comparative purposes. Chemical analyses of the obsidian artifacts and source samples were carried out on a scanning electron microscope using the energy dispersive X-ray spectrometer at the University of Science Malaysia, Penang and the electron microprobe at the University of Malaya, Kuala Lumpur. Multi-elemental analysis and statistical procedures performed on elemental data obtained from the obsidian artifacts and sources provided strong indications that the obsidian artifacts from Ulilang Bundok were made using obsidian obtained from the Nagcarlan source. The chemical sourcing results are significant in that they suggest that obsidian was a limited and valued raw material that was likely mined and traded through expanding social exchange networks. This has further implications for understanding how the complexity and spatial extent of trade reflects emerging social complexity in the Philippines Metal Age

    Redox sulfur chemistry of the copper chaperone Atox1 is regulated by the enzyme glutaredoxin 1, the reduction potential of the glutathione couple GSSG/2GSH and the availability of Cu(I)

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    Glutaredoxins have been characterised as enzymes regulating the redox status of protein thiols via cofactors GSSG/GSH. However, such a function has not been demonstrated with physiologically relevant protein substrates in in vitro experiments. Their active sites frequently feature a Cys-xx-Cys motif that is predicted not to bind metal ions. Such motifs are also present in copper-transporting proteins such as Atox1, a human cytosolic copper metallo-chaperone. In this work, we present the first demonstration that: (i) human glutaredoxin 1 (hGrx1) efficiently catalyses interchange of the dithiol and disulfide forms of the Cys(12)-xx-Cys(15) fragment in Atox1 but does not act upon the isolated single residue Cys(41); (ii) the direction of catalysis is regulated by the GSSG/2GSH ratio and the availability of Cu(I); (iii) the active site Cys(23)-xx-Cys(26) in hGrx1 can bind Cu(I) tightly with femtomolar affinity (K(D) = 10(-15.5) M) and possesses a reduction potential of E(o)\u27 = -118 mV at pH 7.0. In contrast, the Cys(12)-xx-Cys(15) motif in Atox1 has a higher affinity for Cu(I) (K(D) = 10(-17.4) M) and a more negative potential (E(o)\u27 = -188 mV). These differences may be attributed primarily to the very low pKa of Cys23 in hGrx1 and allow rationalisation of conclusion (ii) above: hGrx1 may catalyse the oxidation of Atox1(dithiol) by GSSG, but not the complementary reduction of the oxidised Atox1(disulfide) by GSH unless Cu(aq)(+) is present at a concentration that allows binding of Cu(I) to reduced Atox1 but not to hGrx1. In fact, in the latter case, the catalytic preferences are reversed. Both Cys residues in the active site of hGrx1 are essential for the high affinity Cu(I) binding but the single Cys(23) residue only is required for the redox catalytic function. The molecular properties of both Atox1 and hGrx1 are consistent with a correlation between copper homeostasis and redox sulfur chemistry, as suggested by recent cell experiments. These proteins appear to have evolved the features necessary to fill multiple roles in redox regulation, Cu(I) buffering and Cu(I) transport

    Developing questionnaires for educational research: AMEE Guide No. 87

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    In this AMEE Guide, we consider the design and development of self-administered surveys, commonly called questionnaires. Questionnaires are widely employed in medical education research. Unfortunately, the processes used to develop such questionnaires vary in quality and lack consistent, rigorous standards. Consequently, the quality of the questionnaires used in medical education research is highly variable. To address this problem, this AMEE Guide presents a systematic, seven-step process for designing high-quality questionnaires, with particular emphasis on developing survey scales. These seven steps do not address all aspects of survey design, nor do they represent the only way to develop a high-quality questionnaire. Instead, these steps synthesize multiple survey design techniques and organize them into a cohesive process for questionnaire developers of all levels. Addressing each of these steps systematically will improve the probabilities that survey designers will accurately measure what they intend to measure

    NGC2180: a disrupting open cluster

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    The spatial dependence of luminosity and mass functions of evolved open clusters is discussed in this work using J and H 2MASS photometry. The target objects are the overlooked open cluster NGC2180 and the intermediate-age open cluster NGC3680. We conclude that, although in an advanced dynamical state (mass segregated), NGC3680 does not present strong signs of dissolution. On the other hand, NGC2180 presents flat, eroded LFs throughout its structure, indicating that in addition to mass segregation, Galactic tidal stripping has been effective in depleting this cluster of stars. Accordingly, NGC2180 may be the missing link between evolved open clusters and remnants. We study both clusters in the context of dynamical states estimated from diagnostic-diagrams involving photometric and structural parameters. Both clusters are dynamically evolved systems. In particular, NGC2180 is closer to open cluster remnants than NGC3680.Comment: 9 pages, 8 figure

    BiplotGUI: Interactive Biplots in R

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    Biplots simultaneously provide information on both the samples and the variables ofa data matrix in two- or three-dimensional representations. The BiplotGUI package provides a graphical user interface for the construction of, interaction with, and manipulation of biplots in R. The samples are represented as points, with coordinates determined either by the choice of biplot, principal coordinate analysis or multidimensional scaling. Various transformations and dissimilarity metrics are available. Information on the original variables is incorporated by linear or non-linear calibrated axes. Goodness-of-t measures are provided. Additional descriptors can be superimposed, including convex hulls, alpha-bags, point densities and classication regions. Amongst the interactive features are dynamic variable value prediction, zooming and point and axis drag-and-drop. Output can easily be exported to the R workspace for further manipulation. Three-dimensional biplots are incorporated via the rgl package. The user requires almost no knowledge of R syntax

    Implementing social health insurance in Ireland: Report of a meeting and workshop held in Dublin, on December 6th 2010

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    We considered two basic questions, 'Is it possible to implement Social Health Insurance in Ireland?', and 'How can this be done?'. Can Social Health Insurance be implemented in Ireland? Our answer is a very definite yes. Furthermore, there would be many opportunities, while working towards this end, to improve the performance of our health care system. How can it be implemented? This process will need to be actively managed. There are many difficulties in the Irish health services, but also many opportunities. The greatest strengths are the talented, well-trained and very committed staff. Getting and keeping the support of these staff, for the necessary changes in service delivery, will be critical. Ireland has the capacity to make these changes, but without high quality management, a detailed focussed plan for change, and political support, little will happen. Each step in the change needs to be planned to maintain services, improve service delivery, improve service accountability, and improve service governance. Each sector of the service will need someone to lead the change, and mind that service during the change. Primary care remains under-developed. The HSE plan to develop primary care teams (PCT) has not succeeded. There are several established PCTs which work well. In other areas there are informal arrangements for collaboration, which work well. Overall, there are many useful lessons to learn from the experience so far. Future developments will need to place general practice at the centre of primary care. The mechanisms for doing this will vary from place to place, but need to be developed urgently. Acute hospitals face a crisis of governance. Maurice Hayes' (1) recent report on Tallaght hospital gives an idea of the scale of the changes needed. Tallaght is, we believe, not atypical, and is reputed to be by no means the worst governed hospital in the system. This, alone, should provide a pressing motive for change. Redesigning Irish hospitals to a new mission of supporting primary care, of supporting care in the community where possible can, and must, be done. Long-term care for older people is also a challenge. We advise moving to an integrated needs based system with smooth transitions between different degrees of support at home, and different degrees of support in specialized housing facilities including nursing homes. A similar model should apply to other forms of long-term care, for example for people with a substantial disability. Information systems and management processes both need a major overhaul. The health service remains strikingly under-managed, and fixing this will need a substantial culture change within the services. Wide use of standardized formal project management processes will be vital. There is a separate plan being developed to improve health service IT systems, and implementing this needs to be a high priority. We have not considered other key sectors, for example mental health, disability services, and social services. This does not mean that these are unimportant, merely that we had limited time, and a great deal to cover
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