Optimizing The Inspection Routine For The Detection Of Electrical Energy Theft In Aes Eletropaulo In São Paulo, Brazil

This work describes the development of a non-invasive and low-cost process that allows for the improvement of the energy theft inspection routine, increasing the field inspection team productivity and reducing the customer's embarrassment in cases where no irregularity is found. This new process is based on the development of an electronic Ah meter device that can be installed on the customer's pole input connections to the power lines. Using the recorded Ah value in the device, it is possible to estimate, within a margin of error, the energy consumption of the customer during a small period, typically one week. This energy value is compared to the customer's regular energy meter reading for the same period. A comprehensive statistical study performed with a database of more than 80000 customers in distribution area of the utility company AES Eletropaulo in São Paulo, Brazil concludes that the comparison between these readings can clearly indicate when tampered or defective meters are found.728089Depuru, S., Wang, L., Devabhaktuni, V., Gudi, N., Measures and setbacks for controlling electricity theft (2010) IEEE North American Power Symposium-NAPS(2009) Bureau for Economic Growth, Agriculture and Trade, , U. S. Agency for International Development Washington, D. C., Transforming Electricity Consumers into Customers: Case Study of a Slum Electrification and Loss Reduction Project in São Paulo, BrazilOnat, N., Transmission and distribution losses of Turkey's power system (2010) Proceedings of the 4th WSEAS Conference on Advances in Energy Planning, Environmental Education and Renewable Energy SourcesSmith, T., Electricity theft comparative analysis (2003) Energy Policy, 32, pp. 2067-2076Fitch, M., Graham, C., (2000) Electricity and Gas Theft, , Centre for Utility Consumer Law, University of Leicester, UKKenny, C., Soreide, T., (2008) Grand Corruption in Utilities, , World Bank Policy Research Working Paper 4805Sarpa, C., (2008) Electricity Theft and Non-payment: Impact on the sa Generation Capacity Crisis, , Yelland, Conference PaperOnat, N., Techno-economic analysis of illegal electricity usage in Turkey and policy proposals (2010) WSEAS Transactions on Power Systems, 3, pp. 213-222Stajic, Z., Janjic, A., Simendic, Z., Power quality and electrical energy losses as a key drivers for smart grid platform development (2011) Proceedings of the 15th WSEAS International Conference on Systems - Recent Researches in System Science, pp. 417-422Kadurek, P., Blom, J., Cobben, J., Kling, W., Theft detection and smart metering practices and expectations in the Netherlands (2010) Innovative Smart Grid Technologies Conference Europe (ISGT Europe) IEEE PESOliveira-De Jesus, P., Alvarez, M., De Ponce Leao, M., Yusta, J., A novel approach to evaluate incremental transmission losses (2009) WSEAS Transactions on Power Systems, 1, pp. 12-21Ghajar, R.F., Khalife, J., Cost/benefit analysis of an AMR system to reduce electricity theft and maximize revenues for Électricité du Liban (2003) Applied Energy, 76 (1-3), pp. 25-37. , DOI 10.1016/S0306-2619(03)00044-8Nagi, J., Mohammad, A., Yap, K., Tiong, S., Ahmed, S., Non-technical loss analysis for detection of electricity theft using support vector machines (2008) Proceedings of the 2nd IEEE International Conference on Power and Energy (PECon 08), pp. 907-912(2008) MSP430FE42x Mixed Signal Microcontroller Data-sheet, , Texas Instruments(2011) CC2550 Low-cost Low-power 2.4 GHz RF Transmitter Data-Sheet, , Texas InstrumentsMorais, F., (2011) Development of an Electronic Wireless RMS Current Meter for Applications in Detection of Electrical Energy Theft, , M. Sc. Thesis in Electrical Engineering, Faculty of Computer and Electrical Engineering, University of Campinas, BrazilPomilio, J., Deckmann, S., Characterization and compensation of harmonics and reactive power of residential and commercial loads (2007) IEEE Transactions on Power Delivery,

Microwave dielectric permittivity and photoluminescence of Eu 2O3 doped laser heated pedestal growth Ta 2O5 fibers

Partilhar documento na coleção da comunidade Laboratório Associado I3NWe report the microwave dielectric properties and photoluminescence of undoped and europium oxide doped Ta2O5 fibers, grown by laser heated pedestal growth technique. The effects of Eu2O3 doping 1–3 mol % on the structural, optical, and dielectric properties were investigated. At a frequency of 5 GHz, the undoped material exhibits a dielectric permittivity of 21 and for Eu2O3 doped Ta2O5 samples it increases, reaching up to 36 for the highest doping concentration. Nevertheless, the dielectric losses maintain a very low value. For this wide band gap oxide, Eu3+ optical activation was achieved and the emission is observed up to room temperature. Thus, the transparency and high permittivity make this material promising for electronic devices and microwave applications. © 2008 American Institute of Physics.FCT-PTDC/FIS/66262/06FCT-PTDC/CTM/66195/200

Structural and optical properties on thulium-doped LHPG-grown Ta2O5 fibres

Structural, spectroscopic and dielectric properties of thulium-doped laser-heated pedestal Ta2O5 as-grown fibres were studied. Undoped samples grow preferentially with a single crystalline monoclinic structure. The fibre with the lowest thulium content (0.1 at%) also shows predominantly a monoclinic phase and no intra-4f12 Tm3+ recombination was observed. For sample with the highest thulium amount (1.0 at%), the appearance of a dominant triclinic phase as well as intraionic optical activation was observed. The dependence of photoluminescence on excitation energy allows identification of different site locations of Tm3+ ions in the lattice. The absence of recombination between the first and the ground-state multiplets as well as the temperature dependence of the observed transitions was justified by an efficient energy transfer between the Tm3+ ions. Microwave dielectric properties were investigated using the small perturbation theory. At a frequency of 5 GHz, the undoped material exhibits a dielectric permittivity of 21 and for thulium-doped Ta2O5 samples it decreases to 18 for the highest doping concentration. Nevertheless, the dielectric losses maintain a very low value.FCT - PTDC/CTM/66195/2006FCT - PTDC/FIS/66262/2006FCT - PTDC/FIS/72843/200

Automatic diameter control system applied to the laser heated pedestal growth technique

We described an automatic diameter control system (ADC), for the laser heated pedestal growth technique, that reduces the diameter fluctuations in oxide fibers grown from unreacted and non-sinterized pedestals, to less than 2% of the average fiber diameter, and diminishes the average diameter fluctuation, over the entire length of the fiber, to less than 1%. The ADC apparatus is based on an artificial vision system that controls the pulling speed and the height of the molten zone within a precision of 30 mum. We also show that this system can be used for periodic in situ axial doping the fiber. Pure and Cr3+ doped LaAlO3 and pure LiNbO3 were usedas model materials

Relação entre distância geográfica e variabilidade genética de uma população de Bidens spp. com resistência aos herbicidas inibidores de ALS Relation between geographic distance and genetic variability within a population of Bidens spp. with resistance to ALS inhibitors

Espécies de plantas daninhas apresentam elevada variabilidade genética entre plantas dentro de uma população e exibem potencial para adaptar-se ao manejo realizado para o seu controle. Sementes de picão-preto foram coletadas em uma área retangular de 60 hectares, numa propriedade do município de Almirante Tamandaré do Sul-RS, com suspeita de resistência aos inibidores de ALS e cultivada com soja por aproximadamente 20 anos. Os objetivos deste trabalho foram avaliar a variabilidade genética de acessos de Bidens spp. oriundos de uma única propriedade, verificar a dispersão da resistência na gleba amostrada e determinar a relação entre o coeficiente de similaridade genética e a distância geográfica entre os acessos da mesma população. A área foi dividida em 100 pontos de coleta georreferenciados, dentre os quais apenas 40 possuíam plantas de Bidens spp. Essas sementes foram colocadas em potes plásticos com capacidade de 300 ml e, quando as plântulas apresentavam duas folhas, foram submetidas à aspersão de chlorimuron na dose de 200 g ha-1, para confirmação da resistência. A extração do DNA foi realizada a partir de adaptações de protocolos existentes na literatura. No mínimo 20 plantas de cada ponto amostrado foram utilizadas para a formação de bulk's de DNA. Vinte e seis primers do kit operon foram utilizados. Os acessos de Bidens spp. apresentaram grande variabilidade genética dentro da população. A análise de RAPD não permitiu separar as espécies Bidens pilosa e Bidens subalternans. A resistência aos herbicidas inibidores de ALS está disseminada em toda a área amostrada dentro da propriedade. Não ocorre relação entre distância geográfica e similaridade genética entre os acessos da população.<br>Weed species present high genetic variability among plants within a population and show potential to adapt to control tactics. Seeds of Bidens spp. (BIDSS) were collected in a 60 ha rectangular area, in a property located in Almirante Tamandaré do Sul, RS, with suspected ALS resistance, and cultivated with soybean during approximately 20 years. The objectives of this work were to evaluate the genetic variability of accesses of Bidens spp. collected in only one property, to verify resistance dispersion and to determine the relation between the coefficient of genetic similarity and the geographic distance among accesses of the same population. The area was divided into 100 geo-referenced points of seed samplings, among which only 40 points had BIDSS plants. These seeds had been placed in plastic pots with capacity of 300 mL and when seedlings presented two leaves, they were sprayed with chlorimuron at a dose of 200 of g ha-1 for resistance confirmation. DNA extraction was conducted according to the literature protocols. Twenty plants from each sampled site were used for the formation of DNA bulk. Twenty and six primers of the operon kit were also used. The BIDSS accesses presented great genetic variability within the population. RAPD analysis did not allow the separation of the species Bidens pilosa and Bidens subalternans. The resistance to the ALS inhibitors was spread in all the sampled area inside the property. No relation was verified between geographic distance and genetic similarity, suggesting no founder effect occurred in the area

Comparative Study Of β-carotene And Microencapsulated β-carotene: Evaluation Of Their Genotoxic And Antigenotoxic Effects

β-Carotene (BC) is one of the natural pigments that is most commonly added to food; however, the utilization of BC is limited due to its instability. Microencapsulation techniques are commonly used because they can protect the microencapsulated material from oxidization. Nevertheless, the properties of the encapsulated compounds must be studied. We compared the antigenotoxic potential of pure and microencapsulated β-carotene (mBC) in Wistar rats. Two doses of BC or mBC (2.5 or 5.0. mg/kg) were administered by gavage over a period of 14. days. The final gavage was followed by an injection of doxorubicin (DXR). After 24. h the animals were euthanized. The micronucleus test results showed that when both mBC and DXR were given, only the higher dose was antigenotoxic. The results of the comet assay show that when given in association with DXR, mBC had protective effects in the liver. The differences between the results obtained with BC and mBC suggest that possibly the carotenoid biodisponibility was modified by the process of microencapsulation. In conclusion, mBC does not lose its protective properties, but higher doses must be used to observe antigenotoxic effects. This is the first time that the genotoxicity and antigenotoxicity of a microencapsulated compound was evaluated in vivo. © 2012 Elsevier Ltd.50514181424Agarwal, S., Rao, A.V., Carotenoids and chronic diseases (2000) Drug Metabol. Drug Interact., 17, pp. 189-210Alija, A.J., Bresgen, N., Sommerburg, O., Siems, W., Eckl, P.M., Cytotoxic and genotoxic effects of beta-carotene breakdown products on primary rat hepatocytes (2004) Carcinogenesis, 25, pp. 827-831Arriaga-Alba, M., Rivera-Sanchez, R., Parra-Cervantes, G., Barro-Moreno, F., Flores-Paz, R., Garcia-Jimenez, E., Antimutagenesis of beta-carotene to mutations induced by quinolone on Salmonella typhimurium (2000) Arch. Med. Res., 31, pp. 156-161Augustin, M.A., Hemar, Y., Nano- and micro-structured assemblies for encapsulation of food ingredients (2009) Chem. Soc. Rev., 38, pp. 902-912Barbosa, M.I.M.J., Borsarelli, C.D., Mercadante, A.Z., Light stability of spray-dried bixin encapsulated with different edible polysaccharide preparations (2005) Food Res. Int., 38, pp. 989-994Bisby, R.H., Morgan, C.G., Hamblett, I., Gorman, A.A., Quenching of singlet oxygen by Trolox C, ascorbate, and amino acids: effects of pH and temperature (1999) J. Phys. Chem. A, 103, pp. 7454-7459Boon, C.S., McClements, D.J., Weiss, J., Decker, E.A., Role of iron and hydroperoxides in the degradation of lycopene in oil-in-water emulsions (2009) J. Agric. Food Chem., 57, pp. 2993-2998Boon, C.S., McClements, D.J., Weiss, J., Decker, E.A., Factors influencing the chemical stability of carotenoids in foods (2010) Crit. Rev. Food Sci. Nutr., 50, pp. 515-532Bowen, D.E., Whitwell, J.H., Lillford, L., Henderson, D., Kidd, D., Mc Garry, S., Pearce, G., Kirkland, D.J., Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test (2011) Mutat. Res./Genet. Toxicol. Environ. Mutagen., 722, pp. 7-19Celik, A., Ogenler, O., Comelekoglu, U., The evaluation of micronucleus frequency by acridine orange fluorescent staining in peripheral blood of rats treated with lead acetate (2005) Mutagenesis, 20, pp. 411-415Davies, B.H., (1976) Chemistry and Biochemistry of Plant Pigments, 2, pp. 38-165. , Academic Press, Londonde Vos, W.M., Castenmiller, J.J.M., Hamer, R.J., Brummer, R.J.M., Nutridynamics - Studying the dynamics of food components in products and in the consumer (2006) Curr. Opin. Biotechnol., 17, pp. 217-225Dhawan, A., Bajpayee, M., Parmar, D., Comet assay: a reliable tool for the assessment of DNA damage in different models (2009) Cell Biol. Toxicol., 25, pp. 5-32Druesne-Pecollo, N., Latino-Martel, P., Norat, T., Barrandon, E., Bertrais, S., Galan, P., Hercberg, S., Beta-carotene supplementation and cancer risk: a systematic review and metaanalysis of randomized controlled trials (2010) Int. J. Cancer, 127, pp. 172-184Evangelista, C.M.W., Antunes, L.M.G., Francescato, H.D.C., Bianchi, M.L.P., Effects of the olive, extra virgin olive and canola oils on cisplatin-induced clastogenesis in Wistar rats (2004) Food Chem. Toxicol., 42, pp. 1291-1297Faria, A.F., Mignone, R.A., Montenegro, M.A., Mercadante, A.Z., Borsarelli, C.D., Characterization and singlet oxygen quenching capacity of spray-dried microcapsules of edible biopolymers containing antioxidant molecules (2010) J. Agric. Food Chem., 58, pp. 8004-8011Fenech, M., Nutrition and genome health Nutrigenomics - Opportunities in Asia (2007) Forum Nutr., 60, pp. 49-65Ferreira, A.L.A., Salvadori, D.M.F., Nascimento, M.C.M.O., Rocha, N.S., Correa, C.R., Pereira, E.J., Matsubara, L.S., Ladeira, M.S.P., Tomato-oleoresin supplement prevents doxorubicin-induced cardiac myocyte oxidative DNA damage in rats (2007) Mutat. Res./Genet. Toxicol. Environ. Mutagen., 631, pp. 26-35Gharsallaoui, A., (2008), Microencapsulation of food ingredients by spray-drying, in: SciTopics (Ed.), SciTopics. SciTopicsGradecka-Meesters, D., Palus, J., Prochazka, G., Segerbäck, D., Dziubałtowska, E., Kotova, N., Jenssen, D., Stepnik, M., Assessment of the protective effects of selected dietary anticarcinogens against DNA damage and cytogenetic effects induced by benzo[a]pyrene in C57BL/6J mice (2011) Food Chem. Toxicol., 49, pp. 1674-1683Hayashi, M., Sofuni, T., Morita, T., Simulation study of the effects of multiple treatments in the mouse bone marrow micronucleus test (1991) Mutat. Res., 252, pp. 281-287Hayashi, M., MacGregor, J.T., Gatehouse, D.G., Adler, I.D., Blakey, D.H., Dertinger, S.D., Krishna, G., Sutou, S., In vivo rodent erythrocyte micronucleus assay (2000) II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring. Environ. Mol. Mutagen., 35, pp. 234-252Krinsky, N.I., Johnson, E.J., Carotenoid actions and their relation to health and disease (2005) Mol. Aspects Med., 26, pp. 459-516Kuang, S.S., Oliveira, J.C., Crean, A.M., Microencapsulation as a tool for incorporating bioactive ingredients into food (2010) Crit. Rev. Food Sci. Nutr., 50, pp. 951-968Lissi, E.A., Encinas, M.V., Lemp, E., Rubio, M.A., Singlet oxygen O2(1-Delta-G) bimolecular processes - Solvent and compartmentalization effects (1993) Chem. Rev., 93, pp. 699-723Lu, Q.Y., Hung, J.C., Heber, D., Go, V.L.W., Reuter, V.E., Cordon-Cardo, C., Scher, H.I., Zhang, Z.F., Inverse associations between plasma lycopene and other carotenoids and prostate cancer (2001) Cancer Epidemiol. Biomarkers Prev., 10, pp. 749-756Macgregor, J.T., Heddle, J.A., Hite, M., Margolin, B.H., Ramel, C., Salamone, M.F., Tice, R.R., Wild, D., Guidelines for the conduct of micronucleus assays in mammalian bone-marrow erythrocytes (1987) Mutat. Res., 189, pp. 103-112Maiani, G., Periago Castón, M.J., Catasta, G., Toti, E., Cambrodón, I.G., Bysted, A., Granado-Lorencio, F., Schlemmer, U., Carotenoids: actual knowledge on food sources, intakes, stability and bioavailability and their protective role in humans (2009) Mol. Nutr. Food Res., 53, pp. S194-S218Manca, D., Rovaglio, M., Modeling the controlled release of microencapsulated drugs: theory and experimental validation (2003) Chem. Eng. 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Res., 52, pp. 173-184Namitha, K.K., Negi, P.S., Chemistry and biotechnology of carotenoids (2010) Crit. Rev. Food Sci. Nutr., 50, pp. 728-760Nunes, I.L., Mercadante, A.Z., Encapsulation of lycopene using spray-drying and molecular inclusion processes (2007) Braz. Arch. Biol. Technol., 50, pp. 893-900Ostling, O., Johanson, K.J., Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells (1984) Biochem. Biophys. Res. Commun., 123, pp. 291-298Parada, J., Aguilera, J.M., Food microstructure affects the bioavailability of several nutrients (2007) J. Food Sci., 72, pp. R21-R32Prado, S.M., Buera, M.P., Elizalde, B.E., Structural collapse prevents β-carotene loss in a supercooled polymeric matrix (2005) J. Agric. Food Chem., 54, pp. 79-85Ribeiro, J.C., Antunes, L.M.G., Aissa, A.F., Darin, J.D.C., De Rosso, V.V., Mercadante, A.Z., Bianchi, M.D.P., Evaluation of the genotoxic and antigenotoxic effects after acute and subacute treatments with acai pulp (Euterpe oleracea Mart.) on mice using the erythrocytes micronucleus test and the comet assay (2010) Mutat. Res./Genet. Toxicol. Environ. Mutagen., 695, pp. 22-28Rodriguez-Amaya, D.B., Food carotenoids: analysis, composition and alterations during storage and processing of foods (2003) Forum Nutr., 56, pp. 35-37Salvadori, D.M.F., Ribeiro, L.R., Oliveira, M.D.M., Pereira, C.A.B., Becak, W., The protective effect of beta-carotene on genotoxicity induced by cyclophosphamide (1992) Mutat. Res., 265, pp. 237-244Sendao, M.C., Behling, E.B., dos Santos, R.A., Antunes, L.M.G., Bianchi, M.D.L.P., Comparative effects of acute and subacute lycopene administration on chromosomal aberrations induced by cisplatin in male rats (2006) Food Chem. Toxicol., 44, pp. 1334-1339Sies, H., Stahl, W., Sundquist, A.R., Antioxidant functions of vitamins (1992) Ann. NY Acad. Sci., 669, pp. 7-20Singh, N.P., Mccoy, M.T., Tice, R.R., Schneider, E.L., A Simple Technique for Quantitation of Low-Levels of DNA Damage in Individual Cells (1988) Exp. Cell Res., 175, pp. 184-191Singh, M., Kaur, P., Sandhir, R., Kiran, R., Protective effects of vitamin E against atrazine-induced genotoxicity in rats (2008) Mutat. Res./Genet. Toxicol. Environ. Mutagen., 654, pp. 145-149Tweats, D.J., Blakey, D., Heflich, R.H., Jacobs, A., Jacobsen, S.D., Morita, T., Nohmi, T., Tice, R., Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests - II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test (2007) Mutat. Res./Genet. Toxicol. Environ. Mutagen., 627, pp. 92-105Wang, Y., Lu, Z., Wu, H., Lv, F., Study on the antibiotic activity of microcapsule curcumin against foodborne pathogens (2009) Int. J. 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In Vivo Assessment Of The Cytotoxic, Genotoxic And Antigenotoxic Potential Of Maná-cubiu (solanum Sessiliflorum Dunal) Fruit

Solanum sessiliflorum Dunal is a native shrub often found in the Amazon Forest. Its fruits, known as maná-cubiu, possess an unusual flavor and are consumed in salads and juices, mainly by the local community of Northern Brazil. Because these fruits are used in traditional medicine as hypoglycemic and hypocholesterolemic agents, it is important to establish whether the consumption of maná-cubiu is safe using in vivo genotoxicity tests. Here, we investigated the genotoxic and antigenotoxic potential of maná-cubiu for doxorubicin (DXR)-induced DNA damage using the micronucleus test and the comet assay in Wistar rats. Moreover, oxidative stress parameters were determined in the heart and liver of the animals by measuring the thiobarbituric acid reactive substances (TBARS), a biomarker of lipid peroxidation, and reduced glutathione (GSH) content. The relative expression of Ptgs2 mRNA in the livers of the animals was also determined. The tests were performed with maná-cubiu pulp (125, 250, 375 or 500. mg/kg body weight - b.w.) by gavage for 14. days, followed by intraperitoneal injection of saline or DXR (16. mg/kg b.w.) immediately after the last gavage, which occurred 24. h before euthanasia. The results showed that maná-cubiu at all tested doses had no cytotoxic effects on bone marrow cells and was not genotoxic to heart or liver cells. In addition, maná-cubiu treatments decreased DXR-induced DNA damage according to the comet assay in heart and liver cells. Reductions in micronucleus frequency in peripheral blood cells occurred at 125, 250 and 375. mg/kg b.w. doses of maná-cubiu, and the TBARS content induced by DXR was also reduced by maná-cubiu. Furthermore, maná-cubiu did not modulate the transcription of the Ptgs2 gene. In conclusion, maná-cubiu pulp fruit was not cytotoxic or genotoxic in Wistar rats, suggesting its safety for human consumption, at least considering genotoxic effects. The antioxidant capacity of maná-cubiu pulp fruit may contribute to the antigenotoxic effects of this fruit at the doses used in this study. © 2014 Elsevier Ltd.62121127Aissa, A.F., Bianchi, M.L.P., Ribeiro, J.C., Hernandes, L.C., de Faria, A.F., Mercadante, A.Z., Comparative study of beta-carotene and microencapsulated beta-carotene: Evaluation of their genotoxic and antigenotoxic effects (2012) Food and Chemical Toxicology, 50 (5), pp. 1418-1424Almeida, M.R., Aissa, A.F., Gomes, T.D.U.H., Darin, J.D.C., Chiste, R.C., Mercadante, A.Z., In vivo genotoxicity and oxidative stress evaluation of an ethanolic extract from piquia (Caryocar villosum) pulp (2013) Journal of Medicinal Food, 16 (3), pp. 268-271Boeing, H., Bechthold, A., Bub, A., Ellinger, S., Haller, D., Kroke, A., Critical review: Vegetables and fruit in the prevention of chronic diseases (2012) European Journal of Nutrition, 51 (6), pp. 637-663Bowen, D.E., Whitwell, J.H., Lillford, L., Henderson, D., Kidd, D., Mc Garry, S., Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test (2011) Mutation Research, 722 (1), pp. 7-19Buege, J.A., Aust, S.D., Microsomal lipid peroxidation (1978) Methods in Enzymology, 52, pp. 302-310Carvalho, C., Santos, R.X., Cardoso, S., Correia, S., Oliveira, P.J., Santos, M.S., Doxorubicin: The good, the bad and the ugly effect (2009) Current Medicinal Chemistry, 16 (25), pp. 3267-3285Chang, C.V., Felicio, A.C., Reis, J.E., Guerra Mde, O., Peters, V.M., Fetal toxicity of Solanum lycocarpum (Solanaceae) in rats (2002) Journal of Ethnopharmacology, 81 (2), pp. 265-269de Angelis Pereira, M.C., Carvalho, J.C., Lima, L.M., Caputo, L.R., Ferreira, L.R., Fiorini, J.E., Toxicity of a subchronic treatment with hydroalcoholic crude extract from Solanum grandiflorum (Ruiz et Pav) in rats (2003) Journal of Ethnopharmacology, 89 (1), pp. 97-99Doroshow, J.H., Davies, K.J.A., Redox cycling of anthracyclines by cardiac mitochondria. 2. 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