9,050 research outputs found
Magnetic loop behind an interplanetary shock: Voyager, Helios and IMP-8 observations
The shock was followed by a turbulent sheath in which there were large fluctuations in both the strength and direction of the magnetic field. This in turn was followed by a region (magnetic cloud) in which the magnetic field vectors were observed to change by rotating nearly parallel to a plane, consistent with the passage of a magnetic loop. This loop extended at least 30 deg in longitude between 1-2 AU, and its radial dimension was approximately 0.5 AU. In the cloud the field strength was high and the density and temperature were relatively low. Thus, the dominant pressure in the cloud was that of the magnetic field
Parametric resonance and spin-charge separation in 1D fermionic systems
We show that the periodic modulation of the Hamiltonian parameters for 1D
correlated fermionic systems can be used to parametrically amplify their
bosonic collective modes. Treating the problem within the Luttinger liquid
picture, we show how charge and spin density waves with different momenta are
simultaneously amplified. We discuss the implementation of our predictions for
cold atoms in 1D modulated optical lattices, showing that the fermionic
momentum distribution directly provides a clear signature of spin-charge
separation.Comment: 6 pages, 3 figures, published versio
Temperature-dependent resistivity of suspended graphene
In this paper we investigate the electron-phonon contribution to the
resistivity of suspended single layer graphene. In-plane as well as flexural
phonons are addressed in different temperature regimes. We focus on the
intrinsic electron-phonon coupling due to the interaction of electrons with
elastic deformations in the graphene membrane. The competition between screened
deformation potential vs fictitious gauge field coupling is discussed, together
with the role of tension in the suspended flake. In the absence of tension,
flexural phonons dominate the phonon contribution to the resistivity at any
temperature with a and dependence at low and high
temperatures, respectively. Sample-specific tension suppresses the contribution
due to flexural phonons, yielding a linear temperature dependence due to
in-plane modes. We compare our results with recent experiments.Comment: 11 pages, 3 figure
The effect of individual, group, and shared organizational identification on job satisfaction and collective actual turnover
Drawing on the Social Identity Approach principles, we explored the relationship between organizational identification (individual, group, and shared), job satisfaction, and collective actual turnover. We hypothesize that (a) shared identification moderates the within-person relationship between individual organizational identification and job satisfaction, namely, the effect is stronger for groups in which the level of shared organizational identification is higher; (b) group job satisfaction mediates the relationship between group organizational identification and collective actual turnover. This study was conducted in a large Italian firm (N = 1090; sale locations = 91). Data were collected using both surveys (e.g., job satisfaction) and archive data (collective actual turnover). By means of Bayesian Multilevel Structural Equation Models, we supported the moderating role played by shared organizational identification in the relationship between individual organizational identification and job satisfaction, while no evidence was found for the mediational hypothesis. We discuss the theoretical and practical implications for management
Flexural phonons in free-standing graphene
Rotation and reflection symmetries impose that out-of-plane (flexural)
phonons of free-standing graphene membranes have a quadratic dispersion at long
wavelength and can be excited by charge carriers in pairs only. As a result, we
find that flexural phonons dominate the phonon contribution to the resistivity
below a crossover temperature T_x where we obtain an anomalous
temperature dependence . The logarithmic factor
arises from renormalizations of the flexural phonon dispersion due to coupling
between bending and stretching degrees of freedom of the membrane.Comment: 4 pages, 2 figure
Sequential polarization and imprinting of type 1 T-helper lymphocytes by interferon-γ and interleukin-12
Differentiation of naive T lymphocytes into type I T helper (Th1) cells requires interferon-γ and interleukin-12. It is puzzling that interferon-γ induces the Th1 transcription factor T-bet, whereas interleukin-12 mediates Th1 cell lineage differentiation. We use mathematical modeling to analyze the expression kinetics of T-bet, interferon-γ, and the IL-12 receptor β2 chain (IL-12Rβ2) during Th1 cell differentiation, in the presence or absence of interleukin-12 or interferon-γ signaling. We show that interferon-γ induced initial T-bet expression, whereas IL-12Rβ2 was repressed by T cell receptor (TCR) signaling. The termination of TCR signaling permitted upregulation of IL-12Rβ2 by T-bet and interleukin-12 signaling that maintained T-bet expression. This late expression of T-bet, accompanied by the upregulation of the transcription factors Runx3 and Hlx, was required to imprint the Th cell for interferon-γ re-expression. Thus initial polarization and subsequent imprinting of Th1 cells are mediated by interlinked, sequentially acting positive feedback loops of TCR-interferon-γ-Stat1-T-bet and interleukin-12-Stat4-T-bet signaling
Circulating SIRT1 inversely correlates with epicardial fat thickness in patients with obesity
Background and aim: Obesity is increasing worldwide and is related to undesirable cardiovascular outcomes. Epicardial fat (EF), the heart visceral fat depot, increases with obesity and correlates with cardiovascular risk. SIRT1, an enzyme regulating metabolic circuits linked with obesity, has a cardioprotective effect and is a predictor of cardiovascular events. We aimed to assess the relationship of EF thickness (EFT) with circulating SIRT1 in patients with obesity.
Methods and results: Sixty-two patients affected by obesity and 23 lean controls were studied. Plasma SIRT1 concentration was determined by enzyme-linked immunosorbent assay (ELISA). EFT was measured by echocardiography. Body mass index (BMI), waist circumference, heart rate (HR), blood pressure, and laboratory findings (fasting glucose, insulin, HbA1c, cholesterol, and triglycerides) were assessed. SIRT1 was significantly lower (P = 0.002) and EFT was higher (P < 0.0001) in patients with obesity compared with lean controls. SIRT1 showed a negative correlation with EFT and HR in the obesity group (rho = -0.350, P = 0.005; rho = -0.303, P = 0.008, respectively). After adjustment for obesity-correlated variables, multiple linear regression analysis showed that EFT remained the best correlate of SIRT1 (beta = -0.352, P = 0.016).
Conclusions: Circulating SIRT1 correlates with the visceral fat content of the heart. Serum SIRT1 levels might provide additional information for risk assessment of coronary artery disease in patients with obesity. (C) 2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved
Mangosteen Extract Shows a Potent Insulin Sensitizing Effect in Obese Female Patients: A Prospective Randomized Controlled Pilot Study.
There is a widely acknowledged association between insulin resistance and obesity/type 2 diabetes (T2DM), and insulin sensitizing treatments have proved effective in preventing diabetes and inducing weight loss. Obesity and T2DM are also associated with increased inflammation. Mangosteen is a tropical tree, whose fruits—known for their antioxidant properties—have been recently suggested having a possible further role in the treatment of obesity and T2DM. The objective of this pilot study has been to evaluate safety and efficacy of treatment with mangosteen extract on insulin resistance, weight management, and inflammatory status in obese female patients with insulin resistance. Twenty-two patients were randomized 1:1 to behavioral therapy alone or behavioral therapy and mangosteen and 20 completed the 26-week study. The mangosteen group reported a significant improvement in insulin sensitivity (homeostatic model assessment-insulin resistance, HOMA-IR −53.22% vs. −15.23%, p = 0.004), and no side effect attributable to treatment was reported. Given the positive preliminary results we report and the excellent safety profile, we suggest a possible supplementary role of mangosteen extracts in the treatment of obesity, insulin resistance, and inflammation
NMR and SR detection of unconventional spin dynamics in Er(trensal) and Dy(trensal) molecular magnets
Measurements of proton Nuclear Magnetic Resonance (1H NMR) spectra and
relaxation and of Muon Spin Relaxation (SR) have been performed as a
function of temperature and external magnetic field on two isostructural
lanthanide complexes, Er(trensal) and Dy(trensal) featuring
crystallographically imposed trigonal symmetry. Both the nuclear 1/T1 and muon
longitudinal relaxation rates, LRR, exhibit a peak for temperatures T
lower than 30K, associated to the slowing down of the spin dynamics, and the
width of the NMR absorption spectra starts to increase significantly at T ca.
50K, a temperature sizably higher than the one of the LRR peaks. The LRR peaks
have a field and temperature dependence different from those previously
reported for all Molecular Nanomagnets. They do not follow the
Bloembergen-Purcell-Pound scaling of the amplitude and position in temperature
and field and thus cannot be explained in terms of a single dominating
correlation time c determined by the spin slowing down at low
temperature. Further, for T lower than 50K the spectral width does not follow
the temperature behavior of the magnetic susceptibility chi. We suggest, using
simple qualitative considerations, that the observed behavior is due to a
combination of two different relaxation processes characterized by the
correlation times LT and HT, dominating for T lower than 30K and T
higher than 50K, respectively. Finally, the observed flattening of LRR for T
lower than 5K is suggested to have a quantum origin
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