118 research outputs found

    Self-energies in itinerant magnets: A focus on Fe and Ni

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    We present a detailed study of local and non-local correlations in the electronic structure of elemental transition metals carried out by means of the Quasiparticle Self-consistent GW (QSGW ) and Dynamical Mean Field Theory (DMFT). Recent high resolution ARPES and Haas-van Alphen data of two typical transition metal systems (Fe and Ni) are used as case study. (i) We find that the properties of Fe are very well described by QSGW. Agreement with cyclotron and very clean ARPES measurements is excellent, provided that final-state scattering is taken into account. This establishes the exceptional reliability of QSGW also in metallic systems. (ii) Nonetheless QSGW alone is not able to provide an adequate description of the Ni ARPES data due to strong local spin fluctuations. We surmount this deficiency by combining nonlocal charge fluctuations in QSGW with local spin fluctuations in DMFT (QSGW + 'Magnetic DMFT'). (iii) Finally we show that the dynamics of the local fluctuations are actually not crucial. The addition of an external static field can lead to similarly good results if non-local correlations are included through QSGW

    met overexpression turns human primary osteoblasts into osteosarcomas

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    The MET oncogene was causally involved in the pathogenesis of a rare tumor, i.e., the papillary renal cell carcinoma, in which activating mutations, either germline or somatic, were identified. MET activating mutations are rarely found in other human tumors, whereas at higher frequencies, MET is amplified and/or overexpressed in sporadic tumors of specific histotypes, including osteosarcoma. In this work, we provide experimental evidence that overexpression of the MET oncogene causes and sustains the full-blown transformation of osteoblasts. Overexpression of MET , obtained by lentiviral vector–mediated gene transfer, resulted in the conversion of primary human osteoblasts into osteosarcoma cells, displaying the transformed phenotype in vitro and the distinguishing features of human osteosarcomas in vivo . These included atypical nuclei, aberrant mitoses, production of alkaline phosphatase, secretion of osteoid extracellular matrix, and striking neovascularization. Although with a lower tumorigenicity, this phenotype was superimposable to that observed after transfer of the MET gene activated by mutation. Both transformation and tumorigenesis were fully abrogated when MET expression was quenched by short-hairpin RNA or when signaling was impaired by a dominant-negative MET receptor. These data show that MET overexpression is oncogenic and that it is essential for the maintenance of the cancer phenotype. (Cancer Res 2006; 66(9): 4750-7

    The Additional Representative Images for Legacy (ARI-L) project for the ALMA Science Archive

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    The Additional Representative Images for Legacy (ARI-L) project is a European Development project for ALMA Upgrade approved by the Joint ALMA Observatory (JAO) and the European Southern Observatory (ESO), started in June 2019. It aims to increase the legacy value of the ALMA Science Archive (ASA) by bringing the reduction level of ALMA data from Cycles 2-4 close to that of data from more recent Cycles processed for imaging with the ALMA Pipeline. As of mid-2021 more than 150000 images have been returned to the ASA for public use. At its completion in 2022, the project will have provided enhanced products for at least 70% of the observational data from Cycles 2-4 processable with the ALMA Pipeline. In this paper we present the project rationale, its implementation, and the new opportunities offered to ASA users by the ARI-L products. The ARI-L cubes and images complement the much limited number of archival image products generated during the data quality assurance stages (QA2), which cover only a small fraction of the available data for those Cycles. ARI-L imaging products are highly relevant for many science cases and significantly enhance the possibilities for exploiting archival data. Indeed, ARI-L products facilitate archive access and data usage for science purposes even for non-expert data miners, provide a homogeneous view of all data for better dataset comparisons and download selections, make the archive more accessible to visualization and analysis tools, and enable the generation of preview images and plots similar to those possible for subsequent Cycles.Comment: 15 pages. Accepted for publication in PAS

    On the Role of Inhibition Processes in Modeling Control Strategies for Composting Plants

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    We introduce a mathematical model for the composting process in biocells where several chemical phenomena, like the aerobic biodegradation, the hydrolysis of insoluble substrate and the biomass decay, occur. We investigate the best aeration strategies in presence of inhibition processes due to high concentrations of oxygen. Optimal stategries are obtained as result of a suitable optimal control problem. The dynamics exhibits an enhanced level of the oxygen concentration that guarantees the aerobic feature of the biodegradation process. Then, a nonlinear bioeconomic term is included in the objective functional to take into account of the external operational cost. The role of the economic cost in the control policy is analyzed and discussed

    Decolorization and partial mineralization of a polyazo dye by Bacillus firmus immobilized within tubular polymeric gel

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    The degradation of C.I. Direct red 80, a polyazo dye, was investigated using Bacillus firmus immobilized by entrapment in tubular polymeric gel. This bacterial strain was able to completely decolorize 50 mg/L of C.I. Direct red 80 under anoxic conditions within 12 h and also degrade the reaction intermediates (aromatic amines) during the subsequent 12 h under aerobic conditions. The tubular gel harboring the immobilized cells consisted of anoxic and aerobic regions integrated in a single unit which was ideal for azo dye degradation studies. Results obtained show that effective dye decolorization (97.8%), chemical oxygen demand (COD) reduction (91.7%) and total aromatic amines removal were obtained in 15 h with the immobilized bacterial cell system whereas for the free cells, a hydraulic residence time of 24 h was required for an equivalent performance in a sequential anoxic and aerobic process. Repeated-batch experiments indicate the immobilized cells could decolorize C.I. Direct red 80 and reduce medium COD in five successive batch runs with enhanced activity obtained after each consecutive run, thus suggesting its stability and potential for repeated use in wastewater treatment. UV–visible spectrophotometry and HPLC analysis were used to confirm the partial mineralization of the dye. Data from this study could be used as a reference for the development of effective industrial scale biotechnological process for the removal of dyes and their metabolites in textile wastewater

    Toxicity of wine effluents and assessment of a depuration system for their control: assay with tadpoles of Rhinella arenarum (BUFONIDAE)

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    We evaluated the toxicity of the winery effluent and the efficiency of a symbiotic depuration system by means an experiment with Rhinella arenarum tadpoles. The studied effluent was taken from warehouses during the cleaning season. These effluents subsequently subjected to the purification treatment under evaluation. The effluent samples differentiated into two treatment levels: “raw” where the effluent was evaluated with field conditions and “treated” where the effluent was previously filtered with the symbiotic depuration system. The results of the bioassays compared with the physicochemical parameters determined in the effluent samples. The lethal response had a clear-cut correspondence with the effluent quality assessed utilizing physicochemical parameters. In all cases, dilution of the samples resulted in a significant reduction of their toxicity. It concluded that (a) winery effluents could be harmful to tadpoles of R. arenarum, (b) the symbiotic purification system used to treat wine effluents it would produce a significant reduction in the contaminant levels of the effluent. However, this reduction in contaminant levels does not provide sufficient safety for the release of the effluents into the environment.Fil: Navas Romero, Ana Laura. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - Mendoza. Instituto Argentino de Investigaciones de las Zonas Áridas. Provincia de Mendoza. Instituto Argentino de Investigaciones de las Zonas Áridas. Universidad Nacional de Cuyo. Instituto Argentino de Investigaciones de las Zonas Áridas; ArgentinaFil: Herrera Moratta, Mario Andres. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - Mendoza. Instituto Argentino de Investigaciones de las Zonas Áridas. Provincia de Mendoza. Instituto Argentino de Investigaciones de las Zonas Áridas. Universidad Nacional de Cuyo. Instituto Argentino de Investigaciones de las Zonas Áridas; ArgentinaFil: RodrĂ­guez, MarĂ­a Rosa. Universidad Nacional de San Juan. Facultad de IngenierĂ­a; ArgentinaFil: Quiroga, Lorena Beatriz. Universidad Nacional de San Juan. Facultad de FilosofĂ­a, Humanidades y Artes. Instituto de Ciencias BĂĄsicas; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - San Juan; ArgentinaFil: Echegaray, Marcelo Eduardo. Universidad Nacional de San Juan. Facultad de IngenierĂ­a; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - San Juan; ArgentinaFil: Sanabria, Eduardo Alfredo. Universidad Nacional de San Juan. Facultad de FilosofĂ­a, Humanidades y Artes. Instituto de Ciencias BĂĄsicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Exactas y Naturales; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - San Juan; Argentin

    Merging GW with DMFT and non-local correlations beyond

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    The Italian poor in nineteenth-century Britain

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    SIGLEAvailable from British Library Document Supply Centre-DSC:DX196014 / BLDSC - British Library Document Supply CentreGBUnited Kingdo
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