The effect of cultural origin on COVID-19 infection rates

We examine whether a community’s cultural origin affects COVID-19 infection rates by exploiting cultural differences in the bilingual province of South Tyrol in Northern Italy. We find lower infection rates in municipalities with a relatively higher proportion of German speakers, even after controlling for widely used measures of social and civic capital. Our findings can be explained by a more future-oriented behaviour of German speakers in comparison with Italian speakers

Managers' cultural origin and corporate response to an economic shock

We exploit the exogenous Covid-19 shock in a bicultural area of Italy to identify cultural differences in the way companies respond to economic shocks. Firms with managers of diverse cultural backgrounds resort to different forms of government aid, diverge in their investment decisions, and have different growth rates. These findings are consistent with cultural differences in time preferences and debt aversion. Specifically, we find that the response of managers belonging to a more long-term oriented culture is characterized by a lower recourse to debt, more investments and higher growth rates. Overall, our results show that the cultural origin of managers significantly affects firms’ reaction to economic shocks and real economic outcome

Linearly and Circularly Polarized Emission in Sagittarius A*

We perform general relativistic ray-tracing calculations of the transfer of polarized synchrotron radiation through the relativistic accretion flow in Sagittarius (Sgr) A*. Based on a two-temperature magneto-rotational-instability (MRI) induced accretion mode, the birefringence effects are treated self-consistently. By fitting the spectrum and polarization of Sgr A* from millimeter to near-infrared bands, we are able to not only constrain the basic parameters related to the MRI and the electron heating rate, but also limit the orientation of the accretion torus. These constraints lead to unique polarimetric images, which may be compared with future millimeter and sub-millimeter VLBI observations. In combination with general relativistic MHD simulations, the model has the potential to test the MRI with observations of Sgr A*.Comment: 12 pages, 2 figures, ApJL accepte

Probing the Density in the Galactic Center Region: Wind-Blown Bubbles and High-Energy Proton Constraints

Recent observations of the Galactic center in high-energy gamma-rays (above 0.1TeV) have opened up new ways to study this region, from understanding the emission source of these high-energy photons to constraining the environment in which they are formed. We present a revised theoretical density model of the inner 5pc surrounding Sgr A* based on the fact that the underlying structure of this region is dominated by the winds from the Wolf-Rayet stars orbiting Sgr A*. An ideal probe and application of this density structure is this high energy gamma-ray emission. We assume a proton-scattering model for the production of these gamma-rays and then determine first whether such a model is consistent with the observations and second whether we can use these observations to further constrain the density distribution in the Galactic center.Comment: 36 pages including 17 figures, submitted to ApJ, comments welcom

Stochastic Electron Acceleration in Shell-Type Supernova Remnants II

We discuss the generic characteristics of stochastic particle acceleration by a fully developed turbulence spectrum and show that resonant interactions of particles with high speed waves dominate the acceleration process. To produce the relativistic electrons inferred from the broadband spectrum of a few well-observed shell-type supernova remnants in the leptonic scenario for the TeV emission, fast mode waves must be excited effectively in the downstream and dominate the turbulence in the subsonic phase. Strong collisionless non-relativistic astrophysical shocks are studied with the assumption of a constant Aflven speed. The energy density of non-thermal electrons is found to be comparable to that of the magnetic field. With reasonable parameters, the model explains observations of shell-type supernova remnants. More detailed studies are warranted to better understand the nature of supernova shocks.Comment: 5 pages, 7 figures, submitted to Proceedings of the Conference on "2008 Heidelberg International Symposium on High Energy Gamma-Ray Astronomy

Molecular signatures of aneuploidy-driven adaptive evolution.

Alteration of normal ploidy (aneuploidy) can have a number of opposing effects, such as unbalancing protein abundances and inhibiting cell growth but also accelerating genetic diversification and rapid adaptation. The interplay of these detrimental and beneficial effects remains puzzling. Here, to understand how cells develop tolerance to aneuploidy, we subject disomic (i.e. with an extra chromosome copy) strains of yeast to long-term experimental evolution under strong selection, by forcing disomy maintenance and daily population dilution. We characterize mutations, karyotype alterations and gene expression changes, and dissect the associated molecular strategies. Cells with different extra chromosomes accumulated mutations at distinct rates and displayed diverse adaptive events. They tended to evolve towards normal ploidy through chromosomal DNA loss and gene expression changes. We identify genes with recurrent mutations and altered expression in multiple lines, revealing a variant that improves growth under genotoxic stresses. These findings support rapid evolvability of disomic strains that can be used to characterize fitness effects of mutations under different stress conditions

Occurrence of Grapevine Leafroll-Associated Virus Complex in Napa Valley

Grapevine leafroll disease (GLD) is caused by a complex of several virus species (grapevine leafroll-associated viruses, GLRaV) in the family Closteroviridae. Because of its increasing importance, it is critical to determine which species of GLRaV is predominant in each region where this disease is occurring. A structured sampling design, utilizing a combination of RT-PCR based testing and sequencing methods, was used to survey GLRaVs in Napa Valley (California, USA) vineyards (n = 36). Of the 216 samples tested for GLRaV-1, -2, -3, -4, -5, and -9, 62% (n = 134) were GLRaV positive. Of the positives, 81% (n = 109) were single infections with GLRaV-3, followed by GLRaV-2 (4%, n = 5), while the remaining samples (15%, n = 20) were mixed infections of GLRaV-3 with GLRaV-1, 2, 4, or 9. Additionally, 468 samples were tested for genetic variants of GLRaV-3, and of the 65% (n = 306) of samples positive for GLRaV-3, 22% were infected with multiple GLRaV-3 variants. Phylogenetic analysis utilizing sequence data from the single infection GLRaV-3 samples produced seven well-supported GLRaV-3 variants, of which three represented 71% of all GLRaV-3 positive samples in Napa Valley. Furthermore, two novel variants, which grouped with a divergent isolate from New Zealand (NZ-1), were identified, and these variants comprised 6% of all positive GLRaV-3 samples. Spatial analyses showed that GLRaV-3a, 3b, and 3c were not homogeneously distributed across Napa Valley. Overall, 86% of all blocks (n = 31) were positive for GLRaVs and 90% of positive blocks (n = 28) had two or more GLRaV-3 variants, suggesting complex disease dynamics that might include multiple insect-mediated introduction events

On metastable configurations of small-world networks

We calculate the number of metastable configurations of Ising small-world networks which are constructed upon superimposing sparse Poisson random graphs onto a one-dimensional chain. Our solution is based on replicated transfer-matrix techniques. We examine the denegeracy of the ground state and we find a jump in the entropy of metastable configurations exactly at the crossover between the small-world and the Poisson random graph structures. We also examine the difference in entropy between metastable and all possible configurations, for both ferromagnetic and bond-disordered long-range couplings.Comment: 9 pages, 4 eps figure