Nanofriction behavior of cluster-assembled carbon films

We have characterized the frictional properties of nanostructured (ns) carbon films grown by Supersonic Cluster Beam Deposition (SCBD) via an Atomic Force-Friction Force Microscope (AFM-FFM). The experimental data are discussed on the basis of a modified Amonton's law for friction, stating a linear dependence of friction on load plus an adhesive offset accounting for a finite friction force in the limit of null total applied load. Molecular Dynamics simulations of the interaction of the AFM tip with the nanostructured carbon confirm the validity of the friction model used for this system. Experimental results show that the friction coefficient is not influenced by the nanostructure of the films nor by the relative humidity. On the other hand the adhesion coefficient depends on these parameters.Comment: 22 pages, 6 figures, RevTex

Effect of an antiandrogenic H<inf>2</inf> receptor antagonist on hepatic regeneration in rats

Because biochemical 'feminization' of the liver in males is observed with hepatic regeneration and because the hepatic regenerative response in females is greater than that in males, the posibility that antiandrogens might potentiate liver regeneration was investigated. Before 70% hepatectomy, adult male Wistar rats were treated with cimetidine, and antiandrogenic H2 antagonist, at doses up to 10 times greater than those used clinically. Control animals received either the saline vehicle or ranitidine, an H2 antagonist without antiandrogenic properties. Treatment with cimetidine reduced the hepatic cytosolic androgen receptor content compared with ranitidine treatment. Hepatectomy caused a further reduction in androgen receptor activity in all groups. Hepatic cytosolic estrogen receptor activity was comparable in all groups throughout the study. Moreover, the rate of liver growth and the levels of ornithine decarboxylase and thymidine kinase activity induced as part of the regenerative response were similar in all groups. Thus, cimetidine, despite its ability to bind to androgen receptors, and ranitidine, an H2 receptor antagonist without antiandrogen action, do not modulate the hepatic regenerative response to a 70% partial hepatectomy

A case report of solitary caecal diverticulum presenting with melena

Paper read at a meeting of the Societa` Italiana di Gastroenterologia held in Rome in June 1973. An extensive review of the literature has shown that cases of solitary caecal diverticulum presenting with melena are rare. A case of solitary caecal diverticulum presenting with melena is described and the relevant literature reviewed. Furthermore, the role of diverticular disease in the differential diagnosis of melena is discussed. Diverticula of the caecum are one of the causes of melena and must be considered in the differential diagnosis of rectal bleeding. The case reported here conforms to the group with which hemorrhage as a complication of diverticular disease is usually associated, specifically, elderly people over 60 with hypertension.peer-reviewe

Diverticula of the right colon

Diverticula of the right colon are usually asymptomatic unless they give rise to complications. Asymptomatic diverticula can only be diagnosed radiologically or at post-mortem. In a survey on the incidence of diverticular disease in Malta based on radiology and necropsy studies, 8 cases of diverticula limited to the right colon were found from a total of 5094 barium studies and 80 postmortem investigations. The cases are presented and the relevant literature reviewed. The major complications which may arise from diverticula of the right colon are acute and chronic inflammation and gastrointestinal bleeding. Diverticula of the right colon are uncommon. They rarely give rise to clinical symptoms but should be considered and excluded in the differential diagnosis of doubtful lesions of the right colon.peer-reviewe

Scale-dependent angle of alignment between velocity and magnetic field fluctuations in solar wind turbulence

Under certain conditions, freely decaying magnetohydrodynamic (MHD) turbulence evolves in such a way that velocity and magnetic field fluctuations delta v and delta B approach a state of alignment in which delta v proportional to delta B. This process is called dynamic alignment. Boldyrev has suggested that a similar kind of alignment process occurs as energy cascades from large to small scales through the inertial range in strong incompressible MHD turbulence. In this study, plasma and magnetic field data from the Wind spacecraft, data acquired in the ecliptic plane near 1 AU, are employed to investigate the angle theta(tau) between velocity and magnetic field fluctuations in the solar wind as a function of the time scale tau of the fluctuations and to look for the scaling relation similar to tau(1/4) predicted by Boldyrev. We find that the angle appears to scale like a power law at large inertial range scales, but then deviates from power law behavior at medium to small inertial range scales. We also find that small errors in the velocity vector measurements can lead to large errors in the angle measurements at small time scales. As a result, we cannot rule out the possibility that the observed deviations from power law behavior arise from errors in the velocity measurements. When we fit the data from 2 x 10(3) s to 2 x 10(4) s with a power law of the form proportional to tau(p), our best fit values for p are in the range 0.27-0.36

Anatomical distribution of diverticula of the large intestine

The literature on the anatomical distribution of diverticula in the large intestine has been reviewed and compared with the findings obtained from a survey of 5094 barium investigations carried out in the period 1967-1972. Of 310 patients with colonic diverticula the anatomical distribution of the diverticula was studied in 259. Though there is general agreement that the commonest sites of involvement are the sigmoid and descending colon, the anatomical distribution of diverticula as reported by various authors shows considerable variations; possible reasons for these variations are mentioned. The relation of the age of the patient to the extent or involvement and to the number of diverticula and the age and sex differences between patients with right sided and those with left sided colonic diverticula are discussed.peer-reviewe

Certifying and removing disparate impact

What does it mean for an algorithm to be biased? In U.S. law, unintentional bias is encoded via disparate impact, which occurs when a selection process has widely different outcomes for different groups, even as it appears to be neutral. This legal determination hinges on a definition of a protected class (ethnicity, gender, religious practice) and an explicit description of the process. When the process is implemented using computers, determining disparate impact (and hence bias) is harder. It might not be possible to disclose the process. In addition, even if the process is open, it might be hard to elucidate in a legal setting how the algorithm makes its decisions. Instead of requiring access to the algorithm, we propose making inferences based on the data the algorithm uses. We make four contributions to this problem. First, we link the legal notion of disparate impact to a measure of classification accuracy that while known, has received relatively little attention. Second, we propose a test for disparate impact based on analyzing the information leakage of the protected class from the other data attributes. Third, we describe methods by which data might be made unbiased. Finally, we present empirical evidence supporting the effectiveness of our test for disparate impact and our approach for both masking bias and preserving relevant information in the data. Interestingly, our approach resembles some actual selection practices that have recently received legal scrutiny.Comment: Extended version of paper accepted at 2015 ACM SIGKDD Conference on Knowledge Discovery and Data Minin

Liver transplantation: an unfinished product.

Liver transplantation has become an extraordinarily valuable and useful operation, but one that is not perfect and that has not been exploited to anything like its full potential. Better immunosuppression may become available soon as exemplified by developments with the Japanese drug, FK506. Improved preservation with the UW solution is already here. With these advantages, liver transplantation is certain to become far more widely used than at any time in the past. Examples were cited of innovative approaches using liver transplantation for the treatment of hepatic malignancies

Amelioration of normothermic canine liver ischemia with prostacyclin.

A model of hepatic ischemia was developed in dogs using a pump-driven splanchnic-to-jugular vein bypass during crossclamping of the portal triad. An LD50 was established with three hours of ischemia. PGI2 given for one hour before the ischemic insult ameliorated the ischemic injury and increased survival